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Items: 1 to 50 of 156

1.

The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.

Rosenbaum JC, Bonilla B, Hengel SR, Mertz TM, Herken BW, Kazemier HG, Pressimone CA, Ratterman TC, MacNary E, De Magis A, Kwon Y, Godin SK, Van Houten B, Normolle DP, Sung P, Das SR, Paeschke K, Roberts SA, VanDemark AP, Bernstein KA.

Nat Commun. 2019 Aug 5;10(1):3515. doi: 10.1038/s41467-019-11374-8.

2.

Expression patterns of small numbers of transcripts from functionally-related pathways predict survival in multiple cancers.

Mandel J, Wang H, Normolle DP, Chen W, Yan Q, Lucas PC, Benos PV, Prochownik EV.

BMC Cancer. 2019 Jul 12;19(1):686. doi: 10.1186/s12885-019-5851-6.

3.

Current good manufacturing practices-compliant manufacture and measurement of biotin-labeled red blood cells.

Donnenberg AD, Kanias T, Triulzi DJ, Dennis CJ, Moore LR, Meyer EM, Sinchar D, Kiss JE, Normolle DP, Gladwin MT.

Cytotherapy. 2019 Jul;21(7):793-800. doi: 10.1016/j.jcyt.2019.04.052. Epub 2019 May 14.

PMID:
31097327
4.

Safety and Efficacy of a Five-Fraction Stereotactic Body Radiotherapy Schedule for Centrally Located Non-Small-Cell Lung Cancer: NRG Oncology/RTOG 0813 Trial.

Bezjak A, Paulus R, Gaspar LE, Timmerman RD, Straube WL, Ryan WF, Garces YI, Pu AT, Singh AK, Videtic GM, McGarry RC, Iyengar P, Pantarotto JR, Urbanic JJ, Sun AY, Daly ME, Grills IS, Sperduto P, Normolle DP, Bradley JD, Choy H.

J Clin Oncol. 2019 May 20;37(15):1316-1325. doi: 10.1200/JCO.18.00622. Epub 2019 Apr 3.

PMID:
30943123
5.

Factors influencing recurrence following anatomic lung resection for clinical stage I non-small cell lung cancer.

Schuchert MJ, Normolle DP, Awais O, Pennathur A, Wilson DO, Luketich JD, Landreneau RJ.

Lung Cancer. 2019 Feb;128:145-151. doi: 10.1016/j.lungcan.2018.12.026. Epub 2018 Dec 26.

PMID:
30642447
6.

A phase 2 trial of regorafenib as a single agent in patients with chemotherapy-refractory, advanced, and metastatic biliary tract adenocarcinoma.

Sun W, Patel A, Normolle D, Patel K, Ohr J, Lee JJ, Bahary N, Chu E, Streeter N, Drummond S.

Cancer. 2019 Mar 15;125(6):902-909. doi: 10.1002/cncr.31872. Epub 2018 Dec 18.

PMID:
30561756
7.

Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells.

Asan A, Skoko JJ, Woodcock CC, Wingert BM, Woodcock SR, Normolle D, Huang Y, Stark JM, Camacho CJ, Freeman BA, Neumann CA.

J Biol Chem. 2019 Jan 11;294(2):397-404. doi: 10.1074/jbc.AC118.005899. Epub 2018 Nov 26.

8.

Flow cytometric detection of most proteins in the cell surface proteome is unaffected by trypsin treatment.

Donnenberg VS, Corselli M, Normolle DP, Meyer EM, Donnenberg AD.

Cytometry A. 2018 Aug;93(8):803-810. doi: 10.1002/cyto.a.23525. Epub 2018 Aug 14.

9.

Systemic Depletion of Nerve Growth Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma.

Saloman JL, Singhi AD, Hartman DJ, Normolle DP, Albers KM, Davis BM.

Pancreas. 2018 Aug;47(7):856-863. doi: 10.1097/MPA.0000000000001090.

10.

Location matters in early stage nodal diffuse large B-cell lymphoma.

Lontos K, Tsagianni A, Yuan JM, Normolle DP, Boyiadzis M, Hou JZ, Swerdlow SH, Dorritie KA.

Leuk Lymphoma. 2019 Jan;60(1):250-253. doi: 10.1080/10428194.2018.1471600. Epub 2018 Jun 22. No abstract available.

11.

A phase-1 study of dasatinib plus all-trans retinoic acid in acute myeloid leukemia.

Redner RL, Beumer JH, Kropf P, Agha M, Boyiadzis M, Dorritie K, Farah R, Hou JZ, Im A, Lim SH, Raptis A, Sehgal A, Christner SM, Normolle D, Johnson DE.

Leuk Lymphoma. 2018 Nov;59(11):2595-2601. doi: 10.1080/10428194.2018.1443330. Epub 2018 Apr 4.

12.

Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate.

Singh KB, Hahm ER, Rigatti LH, Normolle DP, Yuan JM, Singh SV.

Cancer Prev Res (Phila). 2018 Jun;11(6):337-346. doi: 10.1158/1940-6207.CAPR-17-0389. Epub 2018 Mar 15.

13.

The Anti-inflammatory Effect of Personalized Omega-3 Fatty Acid Dosing for Reducing Prostaglandin E2 in the Colonic Mucosa Is Attenuated in Obesity.

Djuric Z, Turgeon DK, Sen A, Ren J, Herman K, Ramaswamy D, Zhao L, Ruffin MT 4th, Normolle DP, Smith WL, Brenner DE.

Cancer Prev Res (Phila). 2017 Dec;10(12):729-737. doi: 10.1158/1940-6207.CAPR-17-0091. Epub 2017 Nov 13.

14.

Intracranial Hemorrhage in Patients Newly Diagnosed with Acute Myeloid Leukemia and Hyperleukocytosis.

Lieberman F, Villgran V, Normolle D, Boyiadzis M.

Acta Haematol. 2017;138(2):116-118. doi: 10.1159/000478690. Epub 2017 Sep 1. No abstract available.

PMID:
28858876
15.

Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage: A Phase 2 Clinical Trial.

Feng M, Suresh K, Schipper MJ, Bazzi L, Ben-Josef E, Matuszak MM, Parikh ND, Welling TH, Normolle D, Ten Haken RK, Lawrence TS.

JAMA Oncol. 2018 Jan 1;4(1):40-47. doi: 10.1001/jamaoncol.2017.2303.

16.

LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes.

Zhang Q, Chikina M, Szymczak-Workman AL, Horne W, Kolls JK, Vignali KM, Normolle D, Bettini M, Workman CJ, Vignali DAA.

Sci Immunol. 2017 Mar 31;2(9). pii: eaah4569. doi: 10.1126/sciimmunol.aah4569.

17.

Gemcitabine/nab-paclitaxel as second-line therapy following FOLFIRINOX in metastatic/advanced pancreatic cancer-retrospective analysis of response.

Nguyen KT, Kalyan A, Beasley HS, Singhi AD, Sun W, Zeh HJ, Normolle D, Bahary N.

J Gastrointest Oncol. 2017 Jun;8(3):556-565. doi: 10.21037/jgo.2017.01.23.

18.

Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity.

Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, Bruno TC, Workman CJ, Vignali DAA.

Cell. 2017 Jun 1;169(6):1130-1141.e11. doi: 10.1016/j.cell.2017.05.005. Epub 2017 May 25.

19.

A Multicenter Study of a Fluorescence In Situ Hybridization Probe Set for Diagnosing High-Grade Dysplasia and Adenocarcinoma in Barrett's Esophagus.

Poneros JM, Faye AS, Barr Fritcher EG, Sen A, Anandasabapathy S, Bresalier RS, Marcon N, Turgeon DK, Appelman H, Normolle D, Morrison LE, Brenner DE, Halling KC.

Dig Dis Sci. 2017 May;62(5):1216-1222. doi: 10.1007/s10620-017-4517-y. Epub 2017 Mar 6.

20.

Downregulation of estrogen receptor and modulation of growth of breast cancer cell lines mediated by paracrine stromal cell signals.

Huang J, Woods P, Normolle D, Goff JP, Benos PV, Stehle CJ, Steinman RA.

Breast Cancer Res Treat. 2017 Jan;161(2):229-243. doi: 10.1007/s10549-016-4052-0. Epub 2016 Nov 16.

21.

Intratumor Heterogeneity Affects Gene Expression Profile Test Prognostic Risk Stratification in Early Breast Cancer.

Gyanchandani R, Lin Y, Lin HM, Cooper K, Normolle DP, Brufsky A, Fastuca M, Crosson W, Oesterreich S, Davidson NE, Bhargava R, Dabbs DJ, Lee AV.

Clin Cancer Res. 2016 Nov 1;22(21):5362-5369. Epub 2016 May 16.

22.

5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers.

Van Der Kraak L, Goel G, Ramanan K, Kaltenmeier C, Zhang L, Normolle DP, Freeman GJ, Tang D, Nason KS, Davison JM, Luketich JD, Dhupar R, Lotze MT.

J Immunother Cancer. 2016 Oct 18;4:65. doi: 10.1186/s40425-016-0163-8. eCollection 2016.

23.

Leukapheresis in patients newly diagnosed with acute myeloid leukemia.

Villgran V, Agha M, Raptis A, Hou JZ, Farah R, Lim SH, Redner RL, Im A, Sehgal A, Dorritie KA, Kiss JE, Normolle D, Boyiadzis M.

Transfus Apher Sci. 2016 Oct;55(2):216-220. doi: 10.1016/j.transci.2016.07.001. Epub 2016 Jul 14.

PMID:
27470709
24.

Antigen-specific immunoreactivity and clinical outcome following vaccination with glioma-associated antigen peptides in children with recurrent high-grade gliomas: results of a pilot study.

Pollack IF, Jakacki RI, Butterfield LH, Hamilton RL, Panigrahy A, Normolle DP, Connelly AK, Dibridge S, Mason G, Whiteside TL, Okada H.

J Neurooncol. 2016 Dec;130(3):517-527. Epub 2016 Sep 13.

25.

Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane.

Bauman JE, Zang Y, Sen M, Li C, Wang L, Egner PA, Fahey JW, Normolle DP, Grandis JR, Kensler TW, Johnson DE.

Cancer Prev Res (Phila). 2016 Jul;9(7):547-57. doi: 10.1158/1940-6207.CAPR-15-0290. Epub 2016 Jun 23.

26.

Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease.

Fu J, Li S, Feng R, Ma H, Sabeh F, Roodman GD, Wang J, Robinson S, Guo XE, Lund T, Normolle D, Mapara MY, Weiss SJ, Lentzsch S.

J Clin Invest. 2016 May 2;126(5):1759-72. doi: 10.1172/JCI80276. Epub 2016 Apr 4.

27.

Immune responses and outcome after vaccination with glioma-associated antigen peptides and poly-ICLC in a pilot study for pediatric recurrent low-grade gliomas.

Pollack IF, Jakacki RI, Butterfield LH, Hamilton RL, Panigrahy A, Normolle DP, Connelly AK, Dibridge S, Mason G, Whiteside TL, Okada H.

Neuro Oncol. 2016 Aug;18(8):1157-68. doi: 10.1093/neuonc/now026. Epub 2016 Mar 15.

28.

Phase I Trial of Dose-escalated Whole Liver Irradiation With Hepatic Arterial Fluorodeoxyuridine/Leucovorin and Streptozotocin Followed by Fluorodeoxyuridine/Leucovorin and Chemoembolization for Patients With Neuroendocrine Hepatic Metastases.

Shilkrut M, Sapir E, Hanasoge S, Schipper MJ, Normolle DP, Ben-Josef E, Ensminger W, Lawrence TS, Feng M.

Am J Clin Oncol. 2018 Apr;41(4):326-331. doi: 10.1097/COC.0000000000000276.

29.

Gemcitabine Plus Radiation Therapy for High-Grade Glioma: Long-Term Results of a Phase 1 Dose-Escalation Study.

Kim MM, Camelo-Piragua S, Schipper M, Tao Y, Normolle D, Junck L, Mammoser A, Betz BL, Cao Y, Kim CJ, Heth J, Sagher O, Lawrence TS, Tsien CI.

Int J Radiat Oncol Biol Phys. 2016 Feb 1;94(2):305-11. doi: 10.1016/j.ijrobp.2015.10.032. Epub 2015 Nov 10.

30.

Macrophages and Myeloid Dendritic Cells Lose T Cell-Stimulating Function in Simian Immunodeficiency Virus Infection Associated with Diminished IL-12 and IFN-α Production.

Wonderlich ER, Wu WC, Normolle DP, Barratt-Boyes SM.

J Immunol. 2015 Oct 1;195(7):3284-92. doi: 10.4049/jimmunol.1500683. Epub 2015 Aug 21.

31.

Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma.

Pardee AD, Yano H, Weinstein AM, Ponce AA, Ethridge AD, Normolle DP, Vujanovic L, Mizejewski GJ, Watkins SC, Butterfield LH.

J Immunother Cancer. 2015 Jul 21;3:32. doi: 10.1186/s40425-015-0077-x. eCollection 2015.

32.

Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma.

Boone BA, Bahary N, Zureikat AH, Moser AJ, Normolle DP, Wu WC, Singhi AD, Bao P, Bartlett DL, Liotta LA, Espina V, Loughran P, Lotze MT, Zeh HJ 3rd.

Ann Surg Oncol. 2015 Dec;22(13):4402-10. doi: 10.1245/s10434-015-4566-4. Epub 2015 Apr 24.

33.

Phase I trial of radiotherapy concurrent with twice-weekly gemcitabine for head and neck cancer: translation from preclinical investigations aiming to improve the therapeutic ratio.

Popovtzer A, Normolle D, Worden FP, Prince ME, Chepeha DB, Wolf GT, Bradford CR, Lawrence TS, Eisbruch A.

Transl Oncol. 2014 Aug;7(4):479-83. doi: 10.1016/j.tranon.2014.04.016.

34.

Biomarkers for personalizing omega-3 fatty acid dosing.

Jiang Y, Djuric Z, Sen A, Ren J, Kuklev D, Waters I, Zhao L, Uhlson CL, Hong YH, Murphy RC, Normolle DP, Smith WL, Brenner DE.

Cancer Prev Res (Phila). 2014 Oct;7(10):1011-22. doi: 10.1158/1940-6207.CAPR-14-0134. Epub 2014 Aug 19.

35.

Recurrence and survival outcomes after anatomic segmentectomy versus lobectomy for clinical stage I non-small-cell lung cancer: a propensity-matched analysis.

Landreneau RJ, Normolle DP, Christie NA, Awais O, Wizorek JJ, Abbas G, Pennathur A, Shende M, Weksler B, Luketich JD, Schuchert MJ.

J Clin Oncol. 2014 Aug 10;32(23):2449-55. doi: 10.1200/JCO.2013.50.8762. Epub 2014 Jun 30.

36.

VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells.

Solomon JD, Heitzer MD, Liu TT, Beumer JH, Parise RA, Normolle DP, Leach DA, Buchanan G, DeFranco DB.

Mol Cancer Res. 2014 Aug;12(8):1166-80. doi: 10.1158/1541-7786.MCR-13-0395. Epub 2014 May 13.

37.

Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma.

Stopczynski RE, Normolle DP, Hartman DJ, Ying H, DeBerry JJ, Bielefeldt K, Rhim AD, DePinho RA, Albers KM, Davis BM.

Cancer Res. 2014 Mar 15;74(6):1718-27. doi: 10.1158/0008-5472.CAN-13-2050. Epub 2014 Jan 21.

38.

Response of Merkel cell polyomavirus-positive merkel cell carcinoma xenografts to a survivin inhibitor.

Dresang LR, Guastafierro A, Arora R, Normolle D, Chang Y, Moore PS.

PLoS One. 2013 Nov 18;8(11):e80543. doi: 10.1371/journal.pone.0080543. eCollection 2013.

39.

Concurrent whole brain radiotherapy and bortezomib for brain metastasis.

Lao CD, Friedman J, Tsien CI, Normolle DP, Chapman C, Cao Y, Lee O, Schipper M, Van Poznak C, Hamstra D, Lawrence T, Hayman J, Redman BG.

Radiat Oncol. 2013 Aug 21;8:204. doi: 10.1186/1748-717X-8-204.

40.

Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection.

Kader M, Smith AP, Guiducci C, Wonderlich ER, Normolle D, Watkins SC, Barrat FJ, Barratt-Boyes SM.

PLoS Pathog. 2013;9(7):e1003530. doi: 10.1371/journal.ppat.1003530. Epub 2013 Jul 25.

41.
42.

Longitudinal bone marrow evaluations for myelodysplasia in patients with myeloma before and after treatment with lenalidomide.

Monaghan SA, Dai L, Mapara MY, Normolle DP, Gollin SM, Lentzsch S.

Leuk Lymphoma. 2013 Sep;54(9):1965-74. doi: 10.3109/10428194.2012.755177. Epub 2013 Jan 28.

43.

Fine-needle aspiration of gray zone lesions of the breast: fibroadenoma versus ductal carcinoma.

Jing X, Normolle D, Michael CW.

Diagn Cytopathol. 2013 Sep;41(9):806-11. doi: 10.1002/dc.22914. Epub 2012 Aug 31.

44.

Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: a multicenter study.

Anderson MA, Zolotarevsky E, Cooper KL, Sherman S, Shats O, Whitcomb DC, Lynch HT, Ghiorzo P, Rubinstein WS, Vogel KJ, Sasson AR, Grizzle WE, Ketcham MA, Lee SY, Normolle D, Plonka CM, Mertens AN, Tripon RC, Brand RE.

Am J Gastroenterol. 2012 Nov;107(11):1730-9. doi: 10.1038/ajg.2012.288. Epub 2012 Aug 28.

45.

Randomized phase II trial of urethral sparing intensity modulated radiation therapy in low-risk prostate cancer: implications for focal therapy.

Vainshtein J, Abu-Isa E, Olson KB, Ray ME, Sandler HM, Normolle D, Litzenberg DW, Masi K, Pan C, Hamstra DA.

Radiat Oncol. 2012 Jun 9;7:82. doi: 10.1186/1748-717X-7-82.

46.

NF-κB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells.

Muthuswamy R, Berk E, Junecko BF, Zeh HJ, Zureikat AH, Normolle D, Luong TM, Reinhart TA, Bartlett DL, Kalinski P.

Cancer Res. 2012 Aug 1;72(15):3735-43. doi: 10.1158/0008-5472.CAN-11-4136. Epub 2012 May 16.

47.

Survivin is a therapeutic target in Merkel cell carcinoma.

Arora R, Shuda M, Guastafierro A, Feng H, Toptan T, Tolstov Y, Normolle D, Vollmer LL, Vogt A, Dömling A, Brodsky JL, Chang Y, Moore PS.

Sci Transl Med. 2012 May 9;4(133):133ra56. doi: 10.1126/scitranslmed.3003713.

48.

A phase I/II trial of intensity modulated radiation (IMRT) dose escalation with concurrent fixed-dose rate gemcitabine (FDR-G) in patients with unresectable pancreatic cancer.

Ben-Josef E, Schipper M, Francis IR, Hadley S, Ten-Haken R, Lawrence T, Normolle D, Simeone DM, Sonnenday C, Abrams R, Leslie W, Khan G, Zalupski MM.

Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):1166-71. doi: 10.1016/j.ijrobp.2012.02.051. Epub 2012 Apr 27.

49.

Dosimetric analysis of radiation-induced gastric bleeding.

Feng M, Normolle D, Pan CC, Dawson LA, Amarnath S, Ensminger WD, Lawrence TS, Ten Haken RK.

Int J Radiat Oncol Biol Phys. 2012 Sep 1;84(1):e1-6. doi: 10.1016/j.ijrobp.2012.02.029. Epub 2012 Apr 27.

50.

Prediction of liver function by using magnetic resonance-based portal venous perfusion imaging.

Cao Y, Wang H, Johnson TD, Pan C, Hussain H, Balter JM, Normolle D, Ben-Josef E, Ten Haken RK, Lawrence TS, Feng M.

Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):258-63. doi: 10.1016/j.ijrobp.2012.02.037. Epub 2012 Apr 18.

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