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Items: 7

1.

HIV infection results in clonal expansions containing integrations within pathogenesis-related biological pathways.

Haworth KG, Schefter LE, Norgaard ZK, Ironside C, Adair JE, Kiem HP.

JCI Insight. 2018 Jul 12;3(13). pii: 99127. doi: 10.1172/jci.insight.99127. [Epub ahead of print]

2.

Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy.

Humbert O, Chan F, Rajawat YS, Torgerson TR, Burtner CR, Hubbard NW, Humphrys D, Norgaard ZK, O'Donnell P, Adair JE, Trobridge GD, Scharenberg AM, Felsburg PJ, Rawlings DJ, Kiem HP.

Blood Adv. 2018 May 8;2(9):987-999. doi: 10.1182/bloodadvances.2018016451.

3.

A Nonhuman Primate Transplantation Model to Evaluate Hematopoietic Stem Cell Gene Editing Strategies for β-Hemoglobinopathies.

Humbert O, Peterson CW, Norgaard ZK, Radtke S, Kiem HP.

Mol Ther Methods Clin Dev. 2017 Nov 21;8:75-86. doi: 10.1016/j.omtm.2017.11.005. eCollection 2018 Mar 16.

4.

A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.

Radtke S, Adair JE, Giese MA, Chan YY, Norgaard ZK, Enstrom M, Haworth KG, Schefter LE, Kiem HP.

Sci Transl Med. 2017 Nov 1;9(414). pii: eaan1145. doi: 10.1126/scitranslmed.aan1145.

PMID:
29093179
5.

In Vivo Murine-Matured Human CD3+ Cells as a Preclinical Model for T Cell-Based Immunotherapies.

Haworth KG, Ironside C, Norgaard ZK, Obenza WM, Adair JE, Kiem HP.

Mol Ther Methods Clin Dev. 2017 May 17;6:17-30. doi: 10.1016/j.omtm.2017.05.004. eCollection 2017 Sep 15.

6.

Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates.

Gori JL, Butler JM, Kunar B, Poulos MG, Ginsberg M, Nolan DJ, Norgaard ZK, Adair JE, Rafii S, Kiem HP.

Stem Cells Transl Med. 2017 Mar;6(3):864-876. doi: 10.5966/sctm.2016-0240. Epub 2016 Oct 14.

7.

Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates.

Peterson CW, Wang J, Norman KK, Norgaard ZK, Humbert O, Tse CK, Yan JJ, Trimble RG, Shivak DA, Rebar EJ, Gregory PD, Holmes MC, Kiem HP.

Blood. 2016 May 19;127(20):2416-26. doi: 10.1182/blood-2015-09-672337. Epub 2016 Mar 15.

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