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Breast cancer outcome prediction with tumour tissue images and machine learning.

Turkki R, Byckhov D, Lundin M, Isola J, Nordling S, Kovanen PE, Verrill C, von Smitten K, Joensuu H, Lundin J, Linder N.

Breast Cancer Res Treat. 2019 Aug;177(1):41-52. doi: 10.1007/s10549-019-05281-1. Epub 2019 May 22.


Detection of breast cancer lymph node metastases in frozen sections with a point-of-care low-cost microscope scanner.

Holmström O, Linder N, Moilanen H, Suutala A, Nordling S, Ståhls A, Lundin M, Diwan V, Lundin J.

PLoS One. 2019 Mar 19;14(3):e0208366. doi: 10.1371/journal.pone.0208366. eCollection 2019.


Radical Prostatectomy or Watchful Waiting in Prostate Cancer - 29-Year Follow-up.

Bill-Axelson A, Holmberg L, Garmo H, Taari K, Busch C, Nordling S, Häggman M, Andersson SO, Andrén O, Steineck G, Adami HO, Johansson JE.

N Engl J Med. 2018 Dec 13;379(24):2319-2329. doi: 10.1056/NEJMoa1807801.


Healthcare Resource Use, Cost, and Sick Leave Following Kidney Transplantation in Sweden: A Population-Based, 5-Year, Retrospective Study of Outcomes: COIN.

von Zur-Mühlen B, Wintzell V, Levine A, Rosenlund M, Kilany S, Nordling S, Wadström J.

Ann Transplant. 2018 Dec 14;23:852-866. doi: 10.12659/AOT.911843.


Perfusion of Porcine Kidneys With Macromolecular Heparin Reduces Early Ischemia Reperfusion Injury.

Sedigh A, Nordling S, Carlsson F, Larsson E, Norlin B, Lübenow N, Lennmyr F, Tufveson G, Magnusson PU, Lorant T.

Transplantation. 2019 Feb;103(2):420-427. doi: 10.1097/TP.0000000000002469.


Increased HSF1 expression predicts shorter disease-specific survival of prostate cancer patients following radical prostatectomy.

Björk JK, Ahonen I, Mirtti T, Erickson A, Rannikko A, Bützow A, Nordling S, Lundin J, Lundin M, Sistonen L, Nees M, Åkerfelt M.

Oncotarget. 2018 Jul 27;9(58):31200-31213. doi: 10.18632/oncotarget.25756. eCollection 2018 Jul 27.


Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse.

Nordling S, Brännström J, Carlsson F, Lu B, Salvaris E, Wanders A, Buijs J, Estrada S, Tolmachev V, Cowan PJ, Lorant T, Magnusson PU.

Sci Rep. 2018 Mar 26;8(1):5220. doi: 10.1038/s41598-018-21463-1.


Deep learning based tissue analysis predicts outcome in colorectal cancer.

Bychkov D, Linder N, Turkki R, Nordling S, Kovanen PE, Verrill C, Walliander M, Lundin M, Haglund C, Lundin J.

Sci Rep. 2018 Feb 21;8(1):3395. doi: 10.1038/s41598-018-21758-3.


New prostate cancer grade grouping system predicts survival after radical prostatectomy.

Erickson A, Sandeman K, Lahdensuo K, Nordling S, Kallajoki M, Seikkula H, Bützow A, Vasarainen H, Boström PJ, Taimen P, Rannikko A, Mirtti T.

Hum Pathol. 2018 May;75:159-166. doi: 10.1016/j.humpath.2018.01.027. Epub 2018 Feb 13. No abstract available.


ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer.

Pellinen T, Blom S, Sánchez S, Välimäki K, Mpindi JP, Azegrouz H, Strippoli R, Nieto R, Vitón M, Palacios I, Turkki R, Wang Y, Sánchez-Alvarez M, Nordling S, Bützow A, Mirtti T, Rannikko A, Montoya MC, Kallioniemi O, Del Pozo MA.

Sci Rep. 2018 Feb 5;8(1):2338. doi: 10.1038/s41598-018-20161-2.


Dirofilaria repens transmission in southeastern Finland.

Pietikäinen R, Nordling S, Jokiranta S, Saari S, Heikkinen P, Gardiner C, Kerttula AM, Kantanen T, Nikanorova A, Laaksonen S, Lavikainen A, Oksanen A.

Parasit Vectors. 2017 Nov 10;10(1):561. doi: 10.1186/s13071-017-2499-4.


Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood.

Bongoni AK, Salvaris E, Nordling S, Klymiuk N, Wolf E, Ayares DL, Rieben R, Magnusson PU, Cowan PJ.

Sci Rep. 2017 Jun 30;7(1):4450. doi: 10.1038/s41598-017-04898-w.


Loss of PTEN expression in ERG-negative prostate cancer predicts secondary therapies and leads to shorter disease-specific survival time after radical prostatectomy.

Lahdensuo K, Erickson A, Saarinen I, Seikkula H, Lundin J, Lundin M, Nordling S, Bützow A, Vasarainen H, Boström PJ, Taimen P, Rannikko A, Mirtti T.

Mod Pathol. 2016 Dec;29(12):1565-1574. doi: 10.1038/modpathol.2016.154. Epub 2016 Aug 26.


PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma.

Saukkonen K, Hagström J, Mustonen H, Juuti A, Nordling S, Kallio P, Alitalo K, Seppänen H, Haglund C.

BMC Cancer. 2016 Jul 13;16:472. doi: 10.1186/s12885-016-2497-5.


The Results of Pancreatic Resections and Long-Term Survival for Pancreatic Ductal Adenocarcinoma: A Single-Institution Experience.

Seppänen H, Juuti A, Mustonen H, Haapamäki C, Nordling S, Carpelan-Holmström M, Sirén J, Luettges J, Haglund C, Kiviluoto T.

Scand J Surg. 2017 Mar;106(1):54-61. doi: 10.1177/1457496916645963. Epub 2016 Jun 23.


Tumor-like Chronic Pancreatitis Is Often Autoimmune Pancreatitis.

Ráty S, Sand J, Nordback I, Rinta-Kiikka I, Vasama K, Hagström J, Nordling S, Sirén J, Kiviluoto T, Haglund C.

Anticancer Res. 2015 Nov;35(11):6163-6.


Podocalyxin Is a Marker of Poor Prognosis in Pancreatic Ductal Adenocarcinoma.

Saukkonen K, Hagström J, Mustonen H, Juuti A, Nordling S, Fermér C, Nilsson O, Seppänen H, Haglund C.

PLoS One. 2015 Jun 8;10(6):e0129012. doi: 10.1371/journal.pone.0129012. eCollection 2015.


Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria.

Berg A, Otterdal K, Patel S, Gonca M, David C, Dalen I, Nymo S, Nilsson M, Nordling S, Magnusson PU, Ueland T, Prato M, Giribaldi G, Mollnes TE, Aukrust P, Langeland N, Nilsson PH.

J Infect Dis. 2015 Dec 1;212(11):1835-40. doi: 10.1093/infdis/jiv283. Epub 2015 May 15.


[A way to better quality registries: "The profession should demand open comparisons between labs"].

Silvestri M, Nordling S.

Lakartidningen. 2015 Apr 20;112. pii: DFW4. Swedish. No abstract available.


Vascular repair utilising immobilised heparin conjugate for protection against early activation of inflammation and coagulation.

Nordling S, Hong J, Fromell K, Edin F, Brännström J, Larsson R, Nilsson B, Magnusson PU.

Thromb Haemost. 2015 Jun;113(6):1312-22. doi: 10.1160/TH14-09-0724. Epub 2015 Mar 5.


A novel in vitro model for studying the interactions between human whole blood and endothelium.

Nordling S, Nilsson B, Magnusson PU.

J Vis Exp. 2014 Nov 21;(93):e52112. doi: 10.3791/52112.


Androgen receptor-interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions.

Saeed K, Östling P, Björkman M, Mirtti T, Alanen K, Vesterinen T, Sankila A, Lundin J, Lundin M, Rannikko A, Nordling S, Mpindi JP, Kohonen P, Iljin K, Kallioniemi O, Rantala JK.

Int J Cancer. 2015 Jun 1;136(11):2535-45. doi: 10.1002/ijc.29303. Epub 2014 Nov 20.


Cost-Effectiveness of Fidaxomicin for the Treatment of Clostridium Difficile Infection (CDI) in Sweden.

Van Engen A, Lie X, Norén T, Nordling S, Nørgaard K.

Value Health. 2014 Nov;17(7):A673-4. doi: 10.1016/j.jval.2014.08.2498. Epub 2014 Oct 26. No abstract available.


The Burden of Clostridium Difficile (CDI) Infection in Hospitals, in Denmark, Finland, Norway And Sweden.

Nordling S, Anttila VJ, Norén T, Cockburn E.

Value Health. 2014 Nov;17(7):A670. doi: 10.1016/j.jval.2014.08.2480. Epub 2014 Oct 26. No abstract available.


The Budget Impact of Using Fidaxomicin for Hospitalised Cdi Patients from the Danish Health Care Perspective.

Nordling S, Cockburn E.

Value Health. 2014 Nov;17(7):A668. doi: 10.1016/j.jval.2014.08.2466. Epub 2014 Oct 26. No abstract available.


Radical prostatectomy or watchful waiting in early prostate cancer.

Bill-Axelson A, Holmberg L, Garmo H, Rider JR, Taari K, Busch C, Nordling S, Häggman M, Andersson SO, Spångberg A, Andrén O, Palmgren J, Steineck G, Adami HO, Johansson JE.

N Engl J Med. 2014 Mar 6;370(10):932-42. doi: 10.1056/NEJMoa1311593.


Inflammation and disease duration have a cumulative effect on the risk of dysplasia and carcinoma in IBD: a case-control observational study based on registry data.

Nieminen U, Jussila A, Nordling S, Mustonen H, Färkkilä MA.

Int J Cancer. 2014 Jan 1;134(1):189-96. doi: 10.1002/ijc.28346. Epub 2013 Jul 16.


PSA forms complexes with α1-antichymotrypsin in prostate.

Zhu L, Jäämaa S, Af Hällström TM, Laiho M, Sankila A, Nordling S, Stenman UH, Koistinen H.

Prostate. 2013 Jan;73(2):219-26. doi: 10.1002/pros.22560. Epub 2012 Jul 16.


Effect of image compression and scaling on automated scoring of immunohistochemical stainings and segmentation of tumor epithelium.

Konsti J, Lundin M, Linder N, Haglund C, Blomqvist C, Nevanlinna H, Aaltonen K, Nordling S, Lundin J.

Diagn Pathol. 2012 Mar 21;7:29. doi: 10.1186/1746-1596-7-29.


Identification of tumor epithelium and stroma in tissue microarrays using texture analysis.

Linder N, Konsti J, Turkki R, Rahtu E, Lundin M, Nordling S, Haglund C, Ahonen T, Pietikäinen M, Lundin J.

Diagn Pathol. 2012 Mar 2;7:22. doi: 10.1186/1746-1596-7-22.


Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, Orešič M, Kallioniemi O, Iljin K.

Oncotarget. 2011 Dec;2(12):1176-90.


Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer.

Sahu B, Laakso M, Ovaska K, Mirtti T, Lundin J, Rannikko A, Sankila A, Turunen JP, Lundin M, Konsti J, Vesterinen T, Nordling S, Kallioniemi O, Hautaniemi S, Jänne OA.

EMBO J. 2011 Sep 13;30(19):3962-76. doi: 10.1038/emboj.2011.328.


Radical prostatectomy versus watchful waiting in early prostate cancer.

Bill-Axelson A, Holmberg L, Ruutu M, Garmo H, Stark JR, Busch C, Nordling S, Häggman M, Andersson SO, Bratell S, Spångberg A, Palmgren J, Steineck G, Adami HO, Johansson JE; SPCG-4 Investigators.

N Engl J Med. 2011 May 5;364(18):1708-17. doi: 10.1056/NEJMoa1011967.


MMP-7 as a prognostic marker in colorectal cancer.

Koskensalo S, Louhimo J, Nordling S, Hagström J, Haglund C.

Tumour Biol. 2011 Apr;32(2):259-64. doi: 10.1007/s13277-010-0080-2. Epub 2010 Aug 28.


MMP-7 overexpression is an independent prognostic marker in gastric cancer.

Koskensalo S, Mrena J, Wiksten JP, Nordling S, Kokkola A, Hagström J, Haglund C.

Tumour Biol. 2010 Jun;31(3):149-55. doi: 10.1007/s13277-010-0020-1. Epub 2010 Mar 19.


COX-2 is associated with proliferation and apoptosis markers and serves as an independent prognostic factor in gastric cancer.

Mrena J, Wiksten JP, Kokkola A, Nordling S, Ristimäki A, Haglund C.

Tumour Biol. 2010 Jan;31(1):1-7. doi: 10.1007/s13277-009-0001-4. Epub 2009 Dec 18.


Allergic rhinitis and the common cold--high cost to society.

Hellgren J, Cervin A, Nordling S, Bergman A, Cardell LO.

Allergy. 2010 Jun 1;65(6):776-83. doi: 10.1111/j.1398-9995.2009.02269.x. Epub 2009 Nov 26.


Xanthine oxidoreductase - clinical significance in colorectal cancer and in vitro expression of the protein in human colon cancer cells.

Linder N, Martelin E, Lundin M, Louhimo J, Nordling S, Haglund C, Lundin J.

Eur J Cancer. 2009 Mar;45(4):648-55. doi: 10.1016/j.ejca.2008.10.036. Epub 2008 Dec 26.


Expression of the androgen receptor and syndecan-1 in breast tissue during different hormonal treatments in cynomolgus monkeys.

Hofling M, Ma L, Sahlin L, Haglund C, Nordling S, von Schoultz B, Cline JM.

Climacteric. 2009 Feb;12(1):72-9. doi: 10.1080/13697130802448387.


Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial.

Bill-Axelson A, Holmberg L, Filén F, Ruutu M, Garmo H, Busch C, Nordling S, Häggman M, Andersson SO, Bratell S, Spångberg A, Palmgren J, Adami HO, Johansson JE; Scandinavian Prostate Cancer Group Study Number 4.

J Natl Cancer Inst. 2008 Aug 20;100(16):1144-54. doi: 10.1093/jnci/djn255. Epub 2008 Aug 11.


Tenascin-C expression and its prognostic significance in colorectal cancer.

Lundin M, Nordling S, Lundin J, Haglund C.

Oncology. 2007;72(5-6):403-9. doi: 10.1159/000113490. Epub 2008 Jan 15.


Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer.

Juuti A, Lundin J, Nordling S, Louhimo J, Haglund C.

Oncology. 2006;71(1-2):61-8. Epub 2007 Mar 21.


Ki-67, p53, ER receptors, ploidy and S phase as long-term prognostic factors in T1 node-negative breast cancer.

Railo M, Lundin J, Haglund C, von Smitten K, Nordling S.

Tumour Biol. 2007;28(1):45-51. Epub 2006 Dec 1.


Cytokeratin 14 is not a specific marker for renal oncocytomas.

Nordling S.

Am J Surg Pathol. 2006 Oct;30(10):1337. No abstract available.


Decreased xanthine oxidoreductase is a predictor of poor prognosis in early-stage gastric cancer.

Linder N, Haglund C, Lundin M, Nordling S, Ristimäki A, Kokkola A, Mrena J, Wiksten JP, Lundin J.

J Clin Pathol. 2006 Sep;59(9):965-71.


MMP-2 but not MMP-9 associated with COX-2 and survival in gastric cancer.

Mrena J, Wiksten JP, Nordling S, Kokkola A, Ristimäki A, Haglund C.

J Clin Pathol. 2006 Jun;59(6):618-23.


VEGF-C and COX-2 expression in papillary thyroid cancer.

Siironen P, Ristimäki A, Narko K, Nordling S, Louhimo J, Andersson S, Haapiainen R, Haglund C.

Endocr Relat Cancer. 2006 Jun;13(2):465-73.


Prognostic significance of cyclin A in gastric cancer.

Mrena J, Wiksten JP, Kokkola A, Nordling S, Haglund C, Ristimäki A.

Int J Cancer. 2006 Oct 15;119(8):1897-901.


Cyclooxygenase-2 expression correlates with poor prognosis in pancreatic cancer.

Juuti A, Louhimo J, Nordling S, Ristimäki A, Haglund C.

J Clin Pathol. 2006 Apr;59(4):382-6. Epub 2006 Feb 7.

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