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Items: 1 to 50 of 202

1.

Quantifying autophagy using novel LC3B and p62 TR-FRET assays.

Bresciani A, Spiezia MC, Boggio R, Cariulo C, Nordheim A, Altobelli R, Kuhlbrodt K, Dominguez C, Munoz-Sanjuan I, Wityak J, Fodale V, Marchionini DM, Weiss A.

PLoS One. 2018 Mar 19;13(3):e0194423. doi: 10.1371/journal.pone.0194423. eCollection 2018.

2.

Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease.

Fitzgerald JC, Zimprich A, Carvajal Berrio DA, Schindler KM, Maurer B, Schulte C, Bus C, Hauser AK, Kübler M, Lewin R, Bobbili DR, Schwarz LM, Vartholomaiou E, Brockmann K, Wüst R, Madlung J, Nordheim A, Riess O, Martins LM, Glaab E, May P, Schenke-Layland K, Picard D, Sharma M, Gasser T, Krüger R.

Brain. 2017 Sep 1;140(9):2444-2459. doi: 10.1093/brain/awx202.

PMID:
29050400
3.

Characterization of a novel murine model for spontaneous hemorrhagic stroke using in vivo PET and MR multiparametric imaging.

Castaneda Vega S, Weinl C, Calaminus C, Wang L, Harant M, Ehrlichmann W, Thiele D, Kohlhofer U, Reischl G, Hempel JM, Ernemann U, Quintanilla Martinez L, Nordheim A, Pichler BJ.

Neuroimage. 2017 Jul 15;155:245-256. doi: 10.1016/j.neuroimage.2017.04.071. Epub 2017 May 1.

PMID:
28473286
4.

The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.

Hermanns C, Hampl V, Holzer K, Aigner A, Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S.

Oncogene. 2017 Jun 15;36(24):3464-3476. doi: 10.1038/onc.2016.496. Epub 2017 Jan 23.

PMID:
28114277
5.

Vps4A-mediated tumor suppression upon exosome modulation?

Akrap I, Thavamani A, Nordheim A.

Ann Transl Med. 2016 May;4(9):180. doi: 10.21037/atm.2016.04.18. No abstract available.

6.

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression.

Tatler AL, Habgood A, Porte J, John AE, Stavrou A, Hodge E, Kerama-Likoko C, Violette SM, Weinreb PH, Knox AJ, Laurent G, Parfrey H, Wolters PJ, Wallace W, Alberti S, Nordheim A, Jenkins G.

J Biol Chem. 2016 Apr 29;291(18):9540-53. doi: 10.1074/jbc.M115.692368. Epub 2016 Feb 9.

7.

Frequent DPH3 promoter mutations in skin cancers.

Denisova E, Heidenreich B, Nagore E, Rachakonda PS, Hosen I, Akrap I, Traves V, García-Casado Z, López-Guerrero JA, Requena C, Sanmartin O, Serra-Guillén C, Llombart B, Guillén C, Ferrando J, Gimeno E, Nordheim A, Hemminki K, Kumar R.

Oncotarget. 2015 Nov 3;6(34):35922-30. doi: 10.18632/oncotarget.5771.

8.

Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke.

Weinl C, Castaneda Vega S, Riehle H, Stritt C, Calaminus C, Wolburg H, Mauel S, Breithaupt A, Gruber AD, Wasylyk B, Olson EN, Adams RH, Pichler BJ, Nordheim A.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9914-9. doi: 10.1073/pnas.1509047112. Epub 2015 Jul 28.

9.

The Cellular Proteins Grb2 and DDX3 Are Increased upon Human Cytomegalovirus Infection and Act in a Proviral Fashion.

Cavignac Y, Lieber D, Laib Sampaio K, Madlung J, Lamkemeyer T, Jahn G, Nordheim A, Sinzger C.

PLoS One. 2015 Jun 29;10(6):e0131614. doi: 10.1371/journal.pone.0131614. eCollection 2015.

10.

Neuronal expression of the transcription factor serum response factor modulates myelination in a mouse multiple sclerosis model.

Anastasiadou S, Liebenehm S, Sinske D, Meyer zu Reckendorf C, Moepps B, Nordheim A, Knöll B.

Glia. 2015 Jun;63(6):958-76. doi: 10.1002/glia.22794. Epub 2015 Feb 2.

PMID:
25639799
11.

Dysregulated serum response factor triggers formation of hepatocellular carcinoma.

Ohrnberger S, Thavamani A, Braeuning A, Lipka DB, Kirilov M, Geffers R, Autenrieth SE, Römer M, Zell A, Bonin M, Schwarz M, Schütz G, Schirmacher P, Plass C, Longerich T, Nordheim A.

Hepatology. 2015 Mar;61(3):979-89. doi: 10.1002/hep.27539. Epub 2015 Jan 30. Erratum in: Hepatology. 2015 May;61(5):1772. Authenrieth, Stella E [corrected to Autenrieth, Stella E].

12.

Elk3 deficiency causes transient impairment in post-natal retinal vascular development and formation of tortuous arteries in adult murine retinae.

Weinl C, Wasylyk C, Garcia Garrido M, Sothilingam V, Beck SC, Riehle H, Stritt C, Roux MJ, Seeliger MW, Wasylyk B, Nordheim A.

PLoS One. 2014 Sep 9;9(9):e107048. doi: 10.1371/journal.pone.0107048. eCollection 2014.

13.

Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase.

Werfel S, Jungmann A, Lehmann L, Ksienzyk J, Bekeredjian R, Kaya Z, Leuchs B, Nordheim A, Backs J, Engelhardt S, Katus HA, Müller OJ.

Cardiovasc Res. 2014 Oct 1;104(1):15-23. doi: 10.1093/cvr/cvu174. Epub 2014 Jul 31.

PMID:
25082846
14.

SRF is essential for mesodermal cell migration during elongation of the embryonic body axis.

Schwartz B, Marks M, Wittler L, Werber M, Währisch S, Nordheim A, Herrmann BG, Grote P.

Mech Dev. 2014 Aug;133:23-35. doi: 10.1016/j.mod.2014.07.001. Epub 2014 Jul 11.

15.

MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.

Hinkel R, Trenkwalder T, Petersen B, Husada W, Gesenhues F, Lee S, Hannappel E, Bock-Marquette I, Theisen D, Leitner L, Boekstegers P, Cierniewski C, Müller OJ, le Noble F, Adams RH, Weinl C, Nordheim A, Reichart B, Weber C, Olson E, Posern G, Deindl E, Niemann H, Kupatt C.

Nat Commun. 2014 Jun 9;5:3970. doi: 10.1038/ncomms4970.

PMID:
24910328
16.

SRF regulation - actin branches out.

Nordheim A.

Nat Rev Mol Cell Biol. 2014 Jun;15(6):368. doi: 10.1038/nrm3803. Epub 2014 Apr 30. No abstract available.

PMID:
24781641
17.

The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction.

Stern S, Haverkamp S, Sinske D, Tedeschi A, Naumann U, Di Giovanni S, Kochanek S, Nordheim A, Knöll B.

J Neurosci. 2013 Nov 27;33(48):18836-48. doi: 10.1523/JNEUROSCI.3029-13.2013.

18.

A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.

Wuestefeld T, Pesic M, Rudalska R, Dauch D, Longerich T, Kang TW, Yevsa T, Heinzmann F, Hoenicke L, Hohmeyer A, Potapova A, Rittelmeier I, Jarek M, Geffers R, Scharfe M, Klawonn F, Schirmacher P, Malek NP, Ott M, Nordheim A, Vogel A, Manns MP, Zender L.

Cell. 2013 Apr 11;153(2):389-401. doi: 10.1016/j.cell.2013.03.026.

19.

Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae.

Weinl C, Riehle H, Park D, Stritt C, Beck S, Huber G, Wolburg H, Olson EN, Seeliger MW, Adams RH, Nordheim A.

J Clin Invest. 2013 May;123(5):2193-206. doi: 10.1172/JCI64201. Epub 2013 Apr 8.

20.

Analysis of the Plasmodium falciparum proteasome using Blue Native PAGE and label-free quantitative mass spectrometry.

Sessler N, Krug K, Nordheim A, Mordmüller B, Macek B.

Amino Acids. 2012 Sep;43(3):1119-29. doi: 10.1007/s00726-012-1296-9. Epub 2012 Jul 22.

PMID:
22821270
21.

Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells.

Franz-Wachtel M, Eisler SA, Krug K, Wahl S, Carpy A, Nordheim A, Pfizenmaier K, Hausser A, Macek B.

Mol Cell Proteomics. 2012 May;11(5):160-70. doi: 10.1074/mcp.M111.016014. Epub 2012 Apr 10.

22.

Probabilistic consensus scoring improves tandem mass spectrometry peptide identification.

Nahnsen S, Bertsch A, Rahnenführer J, Nordheim A, Kohlbacher O.

J Proteome Res. 2011 Aug 5;10(8):3332-43. doi: 10.1021/pr2002879. Epub 2011 Jun 23.

PMID:
21644507
23.

Degeneration of the mouse retina upon dysregulated activity of serum response factor.

Sandström J, Heiduschka P, Beck SC, Philippar U, Seeliger MW, Schraermeyer U, Nordheim A.

Mol Vis. 2011 Apr 29;17:1110-27.

24.

Proteomic analysis of the GlnR-mediated response to nitrogen limitation in Streptomyces coelicolor M145.

Tiffert Y, Franz-Wachtel M, Fladerer C, Nordheim A, Reuther J, Wohlleben W, Mast Y.

Appl Microbiol Biotechnol. 2011 Feb;89(4):1149-59. doi: 10.1007/s00253-011-3086-9. Epub 2011 Jan 13.

PMID:
21229241
25.

Staphylococcal major autolysin (Atl) is involved in excretion of cytoplasmic proteins.

Pasztor L, Ziebandt AK, Nega M, Schlag M, Haase S, Franz-Wachtel M, Madlung J, Nordheim A, Heinrichs DE, Götz F.

J Biol Chem. 2010 Nov 19;285(47):36794-803. doi: 10.1074/jbc.M110.167312. Epub 2010 Sep 16.

26.

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis.

Burbulla LF, Schelling C, Kato H, Rapaport D, Woitalla D, Schiesling C, Schulte C, Sharma M, Illig T, Bauer P, Jung S, Nordheim A, Schöls L, Riess O, Krüger R.

Hum Mol Genet. 2010 Nov 15;19(22):4437-52. doi: 10.1093/hmg/ddq370. Epub 2010 Sep 2.

27.

Ternary complex factors SAP-1 and Elk-1, but not net, are functionally equivalent in thymocyte development.

Costello P, Nicolas R, Willoughby J, Wasylyk B, Nordheim A, Treisman R.

J Immunol. 2010 Jul 15;185(2):1082-92. doi: 10.4049/jimmunol.1000472. Epub 2010 Jun 16.

28.

Identification of a novel Plasmopara halstedii elicitor protein combining de novo peptide sequencing algorithms and RACE-PCR.

Jung S, Fladerer C, Braendle F, Madlung J, Spring O, Nordheim A.

Proteome Sci. 2010 May 10;8:24. doi: 10.1186/1477-5956-8-24.

29.

Linking actin dynamics and gene transcription to drive cellular motile functions.

Olson EN, Nordheim A.

Nat Rev Mol Cell Biol. 2010 May;11(5):353-65. doi: 10.1038/nrm2890. Review.

30.

Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models.

Borchert N, Dieterich C, Krug K, Schütz W, Jung S, Nordheim A, Sommer RJ, Macek B.

Genome Res. 2010 Jun;20(6):837-46. doi: 10.1101/gr.103119.109. Epub 2010 Mar 17.

31.

Loss of the serum response factor in the dopamine system leads to hyperactivity.

Parkitna JR, Bilbao A, Rieker C, Engblom D, Piechota M, Nordheim A, Spanagel R, Schütz G.

FASEB J. 2010 Jul;24(7):2427-35. doi: 10.1096/fj.09-151423. Epub 2010 Mar 11.

PMID:
20223941
32.

Optimal de novo design of MRM experiments for rapid assay development in targeted proteomics.

Bertsch A, Jung S, Zerck A, Pfeifer N, Nahnsen S, Henneges C, Nordheim A, Kohlbacher O.

J Proteome Res. 2010 May 7;9(5):2696-704. doi: 10.1021/pr1001803.

PMID:
20201589
33.

Proliferation of human primary vascular smooth muscle cells depends on serum response factor.

Werth D, Grassi G, Konjer N, Dapas B, Farra R, Giansante C, Kandolf R, Guarnieri G, Nordheim A, Heidenreich O.

Eur J Cell Biol. 2010 Feb-Mar;89(2-3):216-24. doi: 10.1016/j.ejcb.2009.12.002. Epub 2010 Jan 22.

PMID:
20096952
34.

Regulation of the pericycle proteome in maize (Zea mays L.) primary roots by RUM1 which is required for lateral root initiation.

Liu Y, von Behrens I, Muthreich N, Schütz W, Nordheim A, Hochholdinger F.

Eur J Cell Biol. 2010 Feb-Mar;89(2-3):236-41. doi: 10.1016/j.ejcb.2009.11.013. Epub 2009 Dec 4.

PMID:
19962783
35.

Regulation of the maize (Zea mays L.) embryo proteome by RTCS which controls seminal root initiation.

Muthreich N, Schützenmeister A, Schütz W, Madlung J, Krug K, Nordheim A, Piepho HP, Hochholdinger F.

Eur J Cell Biol. 2010 Feb-Mar;89(2-3):242-9. doi: 10.1016/j.ejcb.2009.11.014. Epub 2009 Dec 3.

PMID:
19962210
36.

Specification of cortical parenchyma and stele of maize primary roots by asymmetric levels of auxin, cytokinin, and cytokinin-regulated proteins.

Saleem M, Lamkemeyer T, Schützenmeister A, Madlung J, Sakai H, Piepho HP, Nordheim A, Hochholdinger F.

Plant Physiol. 2010 Jan;152(1):4-18. doi: 10.1104/pp.109.150425. Epub 2009 Nov 20.

37.

Downstream of FGF during mesoderm formation in Xenopus: the roles of Elk-1 and Egr-1.

Nentwich O, Dingwell KS, Nordheim A, Smith JC.

Dev Biol. 2009 Dec 15;336(2):313-26. doi: 10.1016/j.ydbio.2009.09.039. Epub 2009 Sep 30.

38.

Functional versatility of transcription factors in the nervous system: the SRF paradigm.

Knöll B, Nordheim A.

Trends Neurosci. 2009 Aug;32(8):432-42. doi: 10.1016/j.tins.2009.05.004. Epub 2009 Jul 28. Review.

PMID:
19643506
39.

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice.

Koegel H, von Tobel L, Schäfer M, Alberti S, Kremmer E, Mauch C, Hohl D, Wang XJ, Beer HD, Bloch W, Nordheim A, Werner S.

J Clin Invest. 2009 Apr;119(4):899-910. doi: 10.1172/JCI37771. Epub 2009 Mar 23.

40.

Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression.

Stritt C, Stern S, Harting K, Manke T, Sinske D, Schwarz H, Vingron M, Nordheim A, Knöll B.

Nat Neurosci. 2009 Apr;12(4):418-27. doi: 10.1038/nn.2280. Epub 2009 Mar 8.

PMID:
19270689
41.

Tissue specific control of the maize (Zea mays L.) embryo, cortical parenchyma, and stele proteomes by RUM1 which regulates seminal and lateral root initiation.

Saleem M, Lamkemeyer T, Schützenmeister A, Fladerer C, Piepho HP, Nordheim A, Hochholdinger F.

J Proteome Res. 2009 May;8(5):2285-97. doi: 10.1021/pr8009287.

PMID:
19267494
42.

Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder.

Sprossmann F, Pankert P, Sausbier U, Wirth A, Zhou XB, Madlung J, Zhao H, Bucurenciu I, Jakob A, Lamkemeyer T, Neuhuber W, Offermanns S, Shipston MJ, Korth M, Nordheim A, Ruth P, Sausbier M.

FEBS J. 2009 Mar;276(6):1680-97. doi: 10.1111/j.1742-4658.2009.06900.x. Epub 2008 Feb 12.

43.

Changes in the effective gravitational field strength affect the state of phosphorylation of stress-related proteins in callus cultures of Arabidopsis thaliana.

Barjaktarović Z, Schütz W, Madlung J, Fladerer C, Nordheim A, Hampp R.

J Exp Bot. 2009;60(3):779-89. doi: 10.1093/jxb/ern324. Epub 2009 Jan 6.

44.

Graft protection in bypass surgery: siRNA-mediated silencing of adhesion molecules.

Walker T, Wendel HP, Raabe C, Wiechnik P, Spranger L, Heidenreich O, Scheule AM, Nordheim A, Ziemer G.

Oligonucleotides. 2009 Mar;19(1):15-21. doi: 10.1089/oli.2008.0148.

PMID:
19125637
45.

Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart.

Niu Z, Iyer D, Conway SJ, Martin JF, Ivey K, Srivastava D, Nordheim A, Schwartz RJ.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17824-9. doi: 10.1073/pnas.0805491105. Epub 2008 Nov 12.

46.

Analysis of nonadditive protein accumulation in young primary roots of a maize (Zea mays L.) F(1)-hybrid compared to its parental inbred lines.

Hoecker N, Lamkemeyer T, Sarholz B, Paschold A, Fladerer C, Madlung J, Wurster K, Stahl M, Piepho HP, Nordheim A, Hochholdinger F.

Proteomics. 2008 Sep;8(18):3882-94. doi: 10.1002/pmic.200800023.

PMID:
18704907
47.

Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin.

Petit MM, Lindskog H, Larsson E, Wasteson P, Athley E, Breuer S, Angstenberger M, Hertfelder D, Mattsson E, Nordheim A, Nelander S, Lindahl P.

Circ Res. 2008 Jul 3;103(1):61-9. doi: 10.1161/CIRCRESAHA.108.177436. Epub 2008 May 29.

PMID:
18511849
48.

An exocyst complex functions in plant cell growth in Arabidopsis and tobacco.

Hála M, Cole R, Synek L, Drdová E, Pecenková T, Nordheim A, Lamkemeyer T, Madlung J, Hochholdinger F, Fowler JE, Zárský V.

Plant Cell. 2008 May;20(5):1330-45. doi: 10.1105/tpc.108.059105. Epub 2008 May 20.

49.

Time-course of changes in amounts of specific proteins upon exposure to hyper-g, 2-D clinorotation, and 3-D random positioning of Arabidopsis cell cultures.

Barjaktarović Z, Nordheim A, Lamkemeyer T, Fladerer C, Madlung J, Hampp R.

J Exp Bot. 2007;58(15-16):4357-63. doi: 10.1093/jxb/erm302.

PMID:
18182437
50.

Severe intestinal obstruction on induced smooth muscle-specific ablation of the transcription factor SRF in adult mice.

Angstenberger M, Wegener JW, Pichler BJ, Judenhofer MS, Feil S, Alberti S, Feil R, Nordheim A.

Gastroenterology. 2007 Dec;133(6):1948-59. Epub 2007 Sep 5.

PMID:
18054566

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