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Items: 1 to 50 of 161

1.

Lipid accumulation impairs lysosomal acid lipase activity in hepatocytes: Evidence in NAFLD patients and cell cultures.

Gomaraschi M, Fracanzani AL, Dongiovanni P, Pavanello C, Giorgio E, Da Dalt L, Norata GD, Calabresi L, Consonni D, Lombardi R, Branchi A, Fargion S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Sep 7;1864(12):158523. doi: 10.1016/j.bbalip.2019.158523. [Epub ahead of print]

PMID:
31505261
2.

Hormonal control of trained immunity: aldosterone at the crossroad between activation of innate immunity and cardiovascular diseases.

Matarese G, Norata GD.

Cardiovasc Res. 2019 Jul 25. pii: cvz191. doi: 10.1093/cvr/cvz191. [Epub ahead of print] No abstract available.

PMID:
31346597
3.

Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism.

Puca AA, Carrizzo A, Spinelli C, Damato A, Ambrosio M, Villa F, Ferrario A, Maciag A, Fornai F, Lenzi P, Valenti V, di Nonno F, Accarino G, Madonna M, Forte M, Calì G, Baragetti A, Norata GD, Catapano AL, Cattaneo M, Izzo R, Trimarco V, Montella F, Versaci F, Auricchio A, Frati G, Sciarretta S, Madeddu P, Ciaglia E, Vecchione C.

Eur Heart J. 2019 Jul 10. pii: ehz459. doi: 10.1093/eurheartj/ehz459. [Epub ahead of print]

PMID:
31289820
4.

Fuel for thought: immunometabolism is a paradigm shift in understanding immunity in cardiovascular disease.

Caligiuri G, Norata GD.

Cardiovasc Res. 2019 Jul 1;115(9):1383-1384. doi: 10.1093/cvr/cvz155. No abstract available.

PMID:
31199480
5.

Immunometabolic function of cholesterol in cardiovascular disease and beyond.

Yvan-Charvet L, Bonacina F, Guinamard RR, Norata GD.

Cardiovasc Res. 2019 Jul 1;115(9):1393-1407. doi: 10.1093/cvr/cvz127.

PMID:
31095280
6.

The Role of Monocytes and Macrophages in Human Atherosclerosis, Plaque Neoangiogenesis, and Atherothrombosis.

Moroni F, Ammirati E, Norata GD, Magnoni M, Camici PG.

Mediators Inflamm. 2019 Apr 4;2019:7434376. doi: 10.1155/2019/7434376. eCollection 2019. Review.

7.

Cholesterol metabolism, pancreatic β-cell function and diabetes.

Perego C, Da Dalt L, Pirillo A, Galli A, Catapano AL, Norata GD.

Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2149-2156. doi: 10.1016/j.bbadis.2019.04.012. Epub 2019 Apr 26. Review.

PMID:
31029825
8.

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes.

Purvis GSD, Collino M, Loiola RA, Baragetti A, Chiazza F, Brovelli M, Sheikh MH, Collotta D, Cento A, Mastrocola R, Aragno M, Cutrin JC, Reutelingsperger C, Grigore L, Catapano AL, Yaqoob MM, Norata GD, Solito E, Thiemermann C.

Front Immunol. 2019 Mar 27;10:571. doi: 10.3389/fimmu.2019.00571. eCollection 2019.

9.

The Interconnection Between Immuno-Metabolism, Diabetes, and CKD.

Bonacina F, Baragetti A, Catapano AL, Norata GD.

Curr Diab Rep. 2019 Mar 19;19(5):21. doi: 10.1007/s11892-019-1143-4. Review.

PMID:
30888513
10.

Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity.

Bonacina F, Moregola A, Porte R, Baragetti A, Bonavita E, Salatin A, Grigore L, Pellegatta F, Molgora M, Sironi M, Barbati E, Mantovani A, Bottazzi B, Catapano AL, Garlanda C, Norata GD.

Cardiovasc Res. 2019 Mar 12. pii: cvz068. doi: 10.1093/cvr/cvz068. [Epub ahead of print]

PMID:
30859179
11.

Lysosomal Acid Lipase: From Cellular Lipid Handler to Immunometabolic Target.

Gomaraschi M, Bonacina F, Norata GD.

Trends Pharmacol Sci. 2019 Feb;40(2):104-115. doi: 10.1016/j.tips.2018.12.006. Epub 2019 Jan 18. Review.

12.

Novel strategies to target proprotein convertase subtilisin kexin 9: beyond monoclonal antibodies.

Seidah NG, Prat A, Pirillo A, Catapano AL, Norata GD.

Cardiovasc Res. 2019 Mar 1;115(3):510-518. doi: 10.1093/cvr/cvz003.

PMID:
30629143
13.

Author Correction: Cluster-assembled zirconia substrates promote long-term differentiation and functioning of human islets of Langerhans.

Galli A, Maffioli E, Sogne E, Moretti S, Di Cairano ES, Negri A, Nonnis S, Norata GD, Bonacina F, Borghi F, Podestà A, Bertuzzi F, Milani P, Lenardi C, Tedeschi G, Perego C.

Sci Rep. 2018 Nov 27;8(1):17472. doi: 10.1038/s41598-018-35958-4.

14.

Corrigendum to "Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation" [Biochim. Biophys. Acta, 1862 (2016) 1182-1190].

Bonacina F, Barbieri SS, Cutuli L, Amadi P, Don A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):262. doi: 10.1016/j.bbadis.2018.09.017. Epub 2018 Oct 16. No abstract available.

PMID:
30340914
15.

Impact of Cardiovascular Risk Factors and Pharmacologic Treatments on Carotid Intraplaque Neovascularization Detected by Contrast-Enhanced Ultrasound.

Magnoni M, Ammirati E, Moroni F, Norata GD, Camici PG.

J Am Soc Echocardiogr. 2019 Jan;32(1):113-120.e6. doi: 10.1016/j.echo.2018.09.001. Epub 2018 Oct 16.

PMID:
30340893
16.

High-density lipoprotein cholesterol levels, cardiovascular disease risk, and cancer: a relation which does not apply to all?

Catapano AL, Pirillo A, Norata GD.

Cardiovasc Res. 2019 Jan 1;115(1):6-7. doi: 10.1093/cvr/cvy247. No abstract available.

PMID:
30295742
17.

Correction: Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

Lorenz MW, Gao L, Ziegelbauer K, Norata GD, Empana JP, Schmidtmann I, Lin HJ, McLachlan S, Bokemark L, Ronkainen K, Amato M, Schminke U, Srinivasan SR, Lind L, Okazaki S, Stehouwer CDA, Willeit P, Polak JF, Steinmetz H, Sander D, Poppert H, Desvarieux M, Ikram MA, Johnsen SH, Staub D, Sirtori CR, Iglseder B, Beloqui O, Engström G, Friera A, Rozza F, Xie W, Parraga G, Grigore L, Plichart M, Blankenberg S, Su TC, Schmidt C, Tuomainen TP, Veglia F, Völzke H, Nijpels G, Willeit J, Sacco RL, Franco OH, Uthoff H, Hedblad B, Suarez C, Izzo R, Zhao D, Wannarong T, Catapano A, Ducimetiere P, Espinola-Klein C, Chien KL, Price JF, Bergström G, Kauhanen J, Tremoli E, Dörr M, Berenson G, Kitagawa K, Dekker JM, Kiechl S, Sitzer M, Bickel H, Rundek T, Hofman A, Mathiesen EB, Castelnuovo S, Landecho MF, Rosvall M, Gabriel R, de Luca N, Liu J, Baldassarre D, Kavousi M, de Groot E, Bots ML, Yanez DN, Thompson SG; PROG-IMT study group.

PLoS One. 2018 Sep 20;13(9):e0204633. doi: 10.1371/journal.pone.0204633. eCollection 2018.

18.

Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.

Bonacina F, Coe D, Wang G, Longhi MP, Baragetti A, Moregola A, Garlaschelli K, Uboldi P, Pellegatta F, Grigore L, Da Dalt L, Annoni A, Gregori S, Xiao Q, Caruso D, Mitro N, Catapano AL, Marelli-Berg FM, Norata GD.

Nat Commun. 2018 Aug 6;9(1):3083. doi: 10.1038/s41467-018-05322-1.

19.

PCSK9 deficiency reduces insulin secretion and promotes glucose intolerance: the role of the low-density lipoprotein receptor.

Da Dalt L, Ruscica M, Bonacina F, Balzarotti G, Dhyani A, Di Cairano E, Baragetti A, Arnaboldi L, De Metrio S, Pellegatta F, Grigore L, Botta M, Macchi C, Uboldi P, Perego C, Catapano AL, Norata GD.

Eur Heart J. 2019 Jan 21;40(4):357-368. doi: 10.1093/eurheartj/ehy357.

20.

Cluster-assembled zirconia substrates promote long-term differentiation and functioning of human islets of Langerhans.

Galli A, Maffioli E, Sogne E, Moretti S, Di Cairano ES, Negri A, Nonnis S, Norata GD, Bonacina F, Borghi F, Podestà A, Bertuzzi F, Milani P, Lenardi C, Tedeschi G, Perego C.

Sci Rep. 2018 Jul 2;8(1):9979. doi: 10.1038/s41598-018-28019-3. Erratum in: Sci Rep. 2018 Nov 27;8(1):17472.

21.

Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth.

Pacella I, Procaccini C, Focaccetti C, Miacci S, Timperi E, Faicchia D, Severa M, Rizzo F, Coccia EM, Bonacina F, Mitro N, Norata GD, Rossetti G, Ranzani V, Pagani M, Giorda E, Wei Y, Matarese G, Barnaba V, Piconese S.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6546-E6555. doi: 10.1073/pnas.1720113115. Epub 2018 Jun 25.

22.

Trained immunity and cardiovascular disease: is it time for translation to humans?

Norata GD.

Cardiovasc Res. 2018 May 1;114(6):e41-e42. doi: 10.1093/cvr/cvy043. No abstract available.

23.

Biological Consequences of Dysfunctional HDL.

Pirillo A, Catapano AL, Norata GD.

Curr Med Chem. 2019;26(9):1644-1664. doi: 10.2174/0929867325666180530110543. Review.

24.

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H, Bonacina F, Wang G, Coe D, Ward EJ, Colamatteo A, Jangani M, Baragetti A, Matarese G, Smith DM, Haas R, Mauro C, Wraith DC, Okkenhaug K, Catapano AL, De Rosa V, Norata GD, Marelli-Berg FM.

Immunity. 2018 Apr 17;48(4):831-832. doi: 10.1016/j.immuni.2018.03.034. No abstract available.

25.

Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

Lorenz MW, Gao L, Ziegelbauer K, Norata GD, Empana JP, Schmidtmann I, Lin HJ, McLachlan S, Bokemark L, Ronkainen K, Amato M, Schminke U, Srinivasan SR, Lind L, Okazaki S, Stehouwer CDA, Willeit P, Polak JF, Steinmetz H, Sander D, Poppert H, Desvarieux M, Ikram MA, Johnsen SH, Staub D, Sirtori CR, Iglseder B, Beloqui O, Engström G, Friera A, Rozza F, Xie W, Parraga G, Grigore L, Plichart M, Blankenberg S, Su TC, Schmidt C, Tuomainen TP, Veglia F, Völzke H, Nijpels G, Willeit J, Sacco RL, Franco OH, Uthoff H, Hedblad B, Suarez C, Izzo R, Zhao D, Wannarong T, Catapano A, Ducimetiere P, Espinola-Klein C, Chien KL, Price JF, Bergström G, Kauhanen J, Tremoli E, Dörr M, Berenson G, Kitagawa K, Dekker JM, Kiechl S, Sitzer M, Bickel H, Rundek T, Hofman A, Mathiesen EB, Castelnuovo S, Landecho MF, Rosvall M, Gabriel R, de Luca N, Liu J, Baldassarre D, Kavousi M, de Groot E, Bots ML, Yanez DN, Thompson SG; PROG-IMT study group.

PLoS One. 2018 Apr 12;13(4):e0191172. doi: 10.1371/journal.pone.0191172. eCollection 2018. Erratum in: PLoS One. 2018 Sep 20;13(9):e0204633.

26.

Zc3h10 is a novel mitochondrial regulator.

Audano M, Pedretti S, Cermenati G, Brioschi E, Diaferia GR, Ghisletti S, Cuomo A, Bonaldi T, Salerno F, Mora M, Grigore L, Garlaschelli K, Baragetti A, Bonacina F, Catapano AL, Norata GD, Crestani M, Caruso D, Saez E, De Fabiani E, Mitro N.

EMBO Rep. 2018 Apr;19(4). pii: e45531. doi: 10.15252/embr.201745531. Epub 2018 Mar 5.

27.

The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis.

Pirillo A, Bonacina F, Norata GD, Catapano AL.

Curr Atheroscler Rep. 2018 Feb 14;20(3):12. doi: 10.1007/s11883-018-0715-0. Review.

28.

Proprotein Convertase Subtilisin-Kexin type-9 (PCSK9) and triglyceride-rich lipoprotein metabolism: Facts and gaps.

Baragetti A, Grejtakova D, Casula M, Olmastroni E, Jotti GS, Norata GD, Catapano AL, Bellosta S.

Pharmacol Res. 2018 Apr;130:1-11. doi: 10.1016/j.phrs.2018.01.025. Epub 2018 Feb 8. Review.

PMID:
29428206
29.

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H, Bonacina F, Wang G, Coe D, Ward EJ, Colamatteo A, Jangani M, Baragetti A, Matarese G, Smith DM, Haas R, Mauro C, Wraith DC, Okkenhaug K, Catapano AL, De Rosa V, Norata GD, Marelli-Berg FM.

Immunity. 2017 Nov 21;47(5):875-889.e10. doi: 10.1016/j.immuni.2017.10.017. Erratum in: Immunity. 2018 Apr 17;48(4):831-832.

30.

Disease trends over time and CD4+CCR5+ T-cells expansion predict carotid atherosclerosis development in patients with systemic lupus erythematosus.

Baragetti A, Ramirez GA, Magnoni M, Garlaschelli K, Grigore L, Berteotti M, Scotti I, Bozzolo E, Berti A, Camici PG, Catapano AL, Manfredi AA, Ammirati E, Norata GD.

Nutr Metab Cardiovasc Dis. 2018 Jan;28(1):53-63. doi: 10.1016/j.numecd.2017.09.001. Epub 2017 Sep 18.

PMID:
29150407
31.

Targeting Cholesterol in Non-ischemic Heart Failure: A Role for LDLR Gene Therapy?

Catapano AL, Pirillo A, Norata GD.

Mol Ther. 2017 Nov 1;25(11):2435-2437. doi: 10.1016/j.ymthe.2017.10.008. Epub 2017 Oct 19. No abstract available.

32.

Anti-PCSK9 antibodies for the treatment of heterozygous familial hypercholesterolemia: patient selection and perspectives.

Catapano AL, Pirillo A, Norata GD.

Vasc Health Risk Manag. 2017 Sep 4;13:343-351. doi: 10.2147/VHRM.S130338. eCollection 2017. Review.

33.

Strategies for the use of nonstatin therapies.

Pirillo A, Norata GD, Catapano AL.

Curr Opin Lipidol. 2017 Dec;28(6):458-464. doi: 10.1097/MOL.0000000000000459. Review.

PMID:
28914630
34.

PCSK9 deficiency results in increased ectopic fat accumulation in experimental models and in humans.

Baragetti A, Balzarotti G, Grigore L, Pellegatta F, Guerrini U, Pisano G, Fracanzani AL, Fargion S, Norata GD, Catapano AL.

Eur J Prev Cardiol. 2017 Nov;24(17):1870-1877. doi: 10.1177/2047487317724342. Epub 2017 Jul 31.

PMID:
28758421
35.

PCSK9 inhibition in statin-intolerant HeFH patients: What's new?

Casula M, Pirillo A, Norata GD, Catapano AL.

Eur J Prev Cardiol. 2017 Sep;24(14):1525-1527. doi: 10.1177/2047487317721980. Epub 2017 Jul 21. No abstract available.

PMID:
28728483
36.

Arctigenin improves vascular tone and decreases inflammation in human saphenous vein.

Daci A, Neziri B, Krasniqi S, Cavolli R, Alaj R, Norata GD, Beretta G.

Eur J Pharmacol. 2017 Sep 5;810:51-56. doi: 10.1016/j.ejphar.2017.06.004. Epub 2017 Jun 8.

PMID:
28603045
37.

A past and present overview of macrophage metabolism and functional outcomes.

Curi R, de Siqueira Mendes R, de Campos Crispin LA, Norata GD, Sampaio SC, Newsholme P.

Clin Sci (Lond). 2017 Jun 15;131(12):1329-1342. doi: 10.1042/CS20170220. Review.

PMID:
28592702
38.

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.

Marat AL, Wallroth A, Lo WT, Müller R, Norata GD, Falasca M, Schultz C, Haucke V.

Science. 2017 Jun 2;356(6341):968-972. doi: 10.1126/science.aaf8310.

PMID:
28572395
39.

Long pentraxin PTX3 as a prognostic marker of cardiovascular mortality in patients with chronic kidney disease.

Baragetti A, Norata GD.

Pol Arch Intern Med. 2017 Mar 31;127(3):152-153. doi: 10.20452/pamw.3989. Epub 2017 Mar 31. No abstract available.

40.

Vascular inflammation and low-density lipoproteins: is cholesterol the link? A lesson from the clinical trials.

Catapano AL, Pirillo A, Norata GD.

Br J Pharmacol. 2017 Nov;174(22):3973-3985. doi: 10.1111/bph.13805. Epub 2017 May 5. Review.

41.

Translating the microRNA signature of microvesicles derived from human coronary artery smooth muscle cells in patients with familial hypercholesterolemia and coronary artery disease.

de Gonzalo-Calvo D, Cenarro A, Garlaschelli K, Pellegatta F, Vilades D, Nasarre L, Camino-Lopez S, Crespo J, Carreras F, Leta R, Catapano AL, Norata GD, Civeira F, Llorente-Cortes V.

J Mol Cell Cardiol. 2017 May;106:55-67. doi: 10.1016/j.yjmcc.2017.03.005. Epub 2017 Mar 23.

PMID:
28342976
42.

T Follicular Helper Cells Promote a Beneficial Gut Ecosystem for Host Metabolic Homeostasis by Sensing Microbiota-Derived Extracellular ATP.

Perruzza L, Gargari G, Proietti M, Fosso B, D'Erchia AM, Faliti CE, Rezzonico-Jost T, Scribano D, Mauri L, Colombo D, Pellegrini G, Moregola A, Mooser C, Pesole G, Nicoletti M, Norata GD, Geuking MB, McCoy KD, Guglielmetti S, Grassi F.

Cell Rep. 2017 Mar 14;18(11):2566-2575. doi: 10.1016/j.celrep.2017.02.061.

43.

Translating the biology of adipokines in atherosclerosis and cardiovascular diseases: Gaps and open questions.

Ruscica M, Baragetti A, Catapano AL, Norata GD.

Nutr Metab Cardiovasc Dis. 2017 May;27(5):379-395. doi: 10.1016/j.numecd.2016.12.005. Epub 2016 Dec 23. Review.

PMID:
28237179
44.

Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals.

Mauro C, Smith J, Cucchi D, Coe D, Fu H, Bonacina F, Baragetti A, Cermenati G, Caruso D, Mitro N, Catapano AL, Ammirati E, Longhi MP, Okkenhaug K, Norata GD, Marelli-Berg FM.

Cell Metab. 2017 Mar 7;25(3):593-609. doi: 10.1016/j.cmet.2017.01.008. Epub 2017 Feb 9.

45.

Circulating CD14+ and CD14highCD16- classical monocytes are reduced in patients with signs of plaque neovascularization in the carotid artery.

Ammirati E, Moroni F, Magnoni M, Di Terlizzi S, Villa C, Sizzano F, Palini A, Garlaschelli K, Tripiciano F, Scotti I, Catapano AL, Manfredi AA, Norata GD, Camici PG.

Atherosclerosis. 2016 Dec;255:171-178. doi: 10.1016/j.atherosclerosis.2016.10.004. Epub 2016 Oct 6.

PMID:
27751505
46.

Epicardial Adipose Tissue (EAT) Thickness Is Associated with Cardiovascular and Liver Damage in Nonalcoholic Fatty Liver Disease.

Fracanzani AL, Pisano G, Consonni D, Tiraboschi S, Baragetti A, Bertelli C, Norata GD, Dongiovanni P, Valenti L, Grigore L, Tonella T, Catapano A, Fargion S.

PLoS One. 2016 Sep 14;11(9):e0162473. doi: 10.1371/journal.pone.0162473. eCollection 2016.

47.

Genetically determined telomeres shortening is associated with carotid atherosclerosis progression and increased incidence of cardiovascular events.

Baragetti A, Palmen J, Garlaschelli K, Grigore L, Humphries SE, Talmud PJ, Catapano AL, Norata GD.

Int J Cardiol. 2016 Nov 15;223:43-45. doi: 10.1016/j.ijcard.2016.08.164. Epub 2016 Aug 8. No abstract available.

PMID:
27532233
48.

Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering.

Norata GD, Tavori H, Pirillo A, Fazio S, Catapano AL.

Cardiovasc Res. 2016 Oct;112(1):429-42. doi: 10.1093/cvr/cvw194. Epub 2016 Aug 5. Review.

49.

Applicability of the 2013 ACC/AHA Risk Assessment and Cholesterol Treatment Guidelines in the real world: results from a multiethnic case-control study.

Magnoni M, Berteotti M, Norata GD, Limite LR, Peretto G, Cristell N, Maseri A, Cianflone D.

Ann Med. 2016;48(4):282-92. doi: 10.3109/07853890.2016.1168934. Epub 2016 Apr 7.

PMID:
27052543
50.

Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation.

Bonacina F, Barbieri SS, Cutuli L, Amadio P, Doni A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta. 2016 Jun;1862(6):1182-90. doi: 10.1016/j.bbadis.2016.03.007. Epub 2016 Mar 11.

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