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Items: 1 to 50 of 144

1.

Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.

Bonacina F, Coe D, Wang G, Longhi MP, Baragetti A, Moregola A, Garlaschelli K, Uboldi P, Pellegatta F, Grigore L, Da Dalt L, Annoni A, Gregori S, Xiao Q, Caruso D, Mitro N, Catapano AL, Marelli-Berg FM, Norata GD.

Nat Commun. 2018 Aug 6;9(1):3083. doi: 10.1038/s41467-018-05322-1.

2.

PCSK9 deficiency reduces insulin secretion and promotes glucose intolerance: the role of the low-density lipoprotein receptor.

Da Dalt L, Ruscica M, Bonacina F, Balzarotti G, Dhyani A, Di Cairano E, Baragetti A, Arnaboldi L, De Metrio S, Pellegatta F, Grigore L, Botta M, Macchi C, Uboldi P, Perego C, Catapano AL, Norata GD.

Eur Heart J. 2018 Jul 2. doi: 10.1093/eurheartj/ehy357. [Epub ahead of print]

PMID:
29982592
3.

Cluster-assembled zirconia substrates promote long-term differentiation and functioning of human islets of Langerhans.

Galli A, Maffioli E, Sogne E, Moretti S, Di Cairano ES, Negri A, Nonnis S, Norata GD, Bonacina F, Borghi F, Podestà A, Bertuzzi F, Milani P, Lenardi C, Tedeschi G, Perego C.

Sci Rep. 2018 Jul 2;8(1):9979. doi: 10.1038/s41598-018-28019-3.

4.

Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth.

Pacella I, Procaccini C, Focaccetti C, Miacci S, Timperi E, Faicchia D, Severa M, Rizzo F, Coccia EM, Bonacina F, Mitro N, Norata GD, Rossetti G, Ranzani V, Pagani M, Giorda E, Wei Y, Matarese G, Barnaba V, Piconese S.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6546-E6555. doi: 10.1073/pnas.1720113115. Epub 2018 Jun 25.

PMID:
29941600
5.

Trained immunity and cardiovascular disease: is it time for translation to humans?

Norata GD.

Cardiovasc Res. 2018 May 1;114(6):e41-e42. doi: 10.1093/cvr/cvy043. No abstract available.

PMID:
29897493
6.

Biological consequences of dysfunctional HDL.

Pirillo A, Catapano AL, Norata GD.

Curr Med Chem. 2018 May 29. doi: 10.2174/0929867325666180530110543. [Epub ahead of print]

PMID:
29848265
7.

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H, Bonacina F, Wang G, Coe D, Ward EJ, Colamatteo A, Jangani M, Baragetti A, Matarese G, Smith DM, Haas R, Mauro C, Wraith DC, Okkenhaug K, Catapano AL, De Rosa V, Norata GD, Marelli-Berg FM.

Immunity. 2018 Apr 17;48(4):831-832. doi: 10.1016/j.immuni.2018.03.034. No abstract available.

8.

Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

Lorenz MW, Gao L, Ziegelbauer K, Norata GD, Empana JP, Schmidtmann I, Lin HJ, McLachlan S, Bokemark L, Ronkainen K, Amato M, Schminke U, Srinivasan SR, Lind L, Okazaki S, Stehouwer CDA, Willeit P, Polak JF, Steinmetz H, Sander D, Poppert H, Desvarieux M, Ikram MA, Johnsen SH, Staub D, Sirtori CR, Iglseder B, Beloqui O, Engström G, Friera A, Rozza F, Xie W, Parraga G, Grigore L, Plichart M, Blankenberg S, Su TC, Schmidt C, Tuomainen TP, Veglia F, Völzke H, Nijpels G, Willeit J, Sacco RL, Franco OH, Uthoff H, Hedblad B, Suarez C, Izzo R, Zhao D, Wannarong T, Catapano A, Ducimetiere P, Espinola-Klein C, Chien KL, Price JF, Bergström G, Kauhanen J, Tremoli E, Dörr M, Berenson G, Kitagawa K, Dekker JM, Kiechl S, Sitzer M, Bickel H, Rundek T, Hofman A, Mathiesen EB, Castelnuovo S, Landecho MF, Rosvall M, Gabriel R, de Luca N, Liu J, Baldassarre D, Kavousi M, de Groot E, Bots ML, Yanez DN, Thompson SG; PROG-IMT study group.

PLoS One. 2018 Apr 12;13(4):e0191172. doi: 10.1371/journal.pone.0191172. eCollection 2018.

9.

Zc3h10 is a novel mitochondrial regulator.

Audano M, Pedretti S, Cermenati G, Brioschi E, Diaferia GR, Ghisletti S, Cuomo A, Bonaldi T, Salerno F, Mora M, Grigore L, Garlaschelli K, Baragetti A, Bonacina F, Catapano AL, Norata GD, Crestani M, Caruso D, Saez E, De Fabiani E, Mitro N.

EMBO Rep. 2018 Apr;19(4). pii: e45531. doi: 10.15252/embr.201745531. Epub 2018 Mar 5.

PMID:
29507079
10.

The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis.

Pirillo A, Bonacina F, Norata GD, Catapano AL.

Curr Atheroscler Rep. 2018 Feb 14;20(3):12. doi: 10.1007/s11883-018-0715-0. Review.

PMID:
29445885
11.

Proprotein Convertase Subtilisin-Kexin type-9 (PCSK9) and triglyceride-rich lipoprotein metabolism: Facts and gaps.

Baragetti A, Grejtakova D, Casula M, Olmastroni E, Jotti GS, Norata GD, Catapano AL, Bellosta S.

Pharmacol Res. 2018 Apr;130:1-11. doi: 10.1016/j.phrs.2018.01.025. Epub 2018 Feb 8. Review.

PMID:
29428206
12.

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H, Bonacina F, Wang G, Coe D, Ward EJ, Colamatteo A, Jangani M, Baragetti A, Matarese G, Smith DM, Haas R, Mauro C, Wraith DC, Okkenhaug K, Catapano AL, De Rosa V, Norata GD, Marelli-Berg FM.

Immunity. 2017 Nov 21;47(5):875-889.e10. doi: 10.1016/j.immuni.2017.10.017. Erratum in: Immunity. 2018 Apr 17;48(4):831-832.

13.

Disease trends over time and CD4+CCR5+ T-cells expansion predict carotid atherosclerosis development in patients with systemic lupus erythematosus.

Baragetti A, Ramirez GA, Magnoni M, Garlaschelli K, Grigore L, Berteotti M, Scotti I, Bozzolo E, Berti A, Camici PG, Catapano AL, Manfredi AA, Ammirati E, Norata GD.

Nutr Metab Cardiovasc Dis. 2018 Jan;28(1):53-63. doi: 10.1016/j.numecd.2017.09.001. Epub 2017 Sep 18.

PMID:
29150407
14.

Targeting Cholesterol in Non-ischemic Heart Failure: A Role for LDLR Gene Therapy?

Catapano AL, Pirillo A, Norata GD.

Mol Ther. 2017 Nov 1;25(11):2435-2437. doi: 10.1016/j.ymthe.2017.10.008. Epub 2017 Oct 19. No abstract available.

PMID:
29056399
15.

Anti-PCSK9 antibodies for the treatment of heterozygous familial hypercholesterolemia: patient selection and perspectives.

Catapano AL, Pirillo A, Norata GD.

Vasc Health Risk Manag. 2017 Sep 4;13:343-351. doi: 10.2147/VHRM.S130338. eCollection 2017. Review.

16.

Strategies for the use of nonstatin therapies.

Pirillo A, Norata GD, Catapano AL.

Curr Opin Lipidol. 2017 Dec;28(6):458-464. doi: 10.1097/MOL.0000000000000459. Review.

PMID:
28914630
17.

PCSK9 deficiency results in increased ectopic fat accumulation in experimental models and in humans.

Baragetti A, Balzarotti G, Grigore L, Pellegatta F, Guerrini U, Pisano G, Fracanzani AL, Fargion S, Norata GD, Catapano AL.

Eur J Prev Cardiol. 2017 Nov;24(17):1870-1877. doi: 10.1177/2047487317724342. Epub 2017 Jul 31.

PMID:
28758421
18.

PCSK9 inhibition in statin-intolerant HeFH patients: What's new?

Casula M, Pirillo A, Norata GD, Catapano AL.

Eur J Prev Cardiol. 2017 Sep;24(14):1525-1527. doi: 10.1177/2047487317721980. Epub 2017 Jul 21. No abstract available.

PMID:
28728483
19.

Arctigenin improves vascular tone and decreases inflammation in human saphenous vein.

Daci A, Neziri B, Krasniqi S, Cavolli R, Alaj R, Norata GD, Beretta G.

Eur J Pharmacol. 2017 Sep 5;810:51-56. doi: 10.1016/j.ejphar.2017.06.004. Epub 2017 Jun 8.

PMID:
28603045
20.

A past and present overview of macrophage metabolism and functional outcomes.

Curi R, de Siqueira Mendes R, de Campos Crispin LA, Norata GD, Sampaio SC, Newsholme P.

Clin Sci (Lond). 2017 Jun 15;131(12):1329-1342. doi: 10.1042/CS20170220. Review.

PMID:
28592702
21.

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.

Marat AL, Wallroth A, Lo WT, Müller R, Norata GD, Falasca M, Schultz C, Haucke V.

Science. 2017 Jun 2;356(6341):968-972. doi: 10.1126/science.aaf8310.

PMID:
28572395
22.

Long pentraxin PTX3 as a prognostic marker of cardiovascular mortality in patients with chronic kidney disease.

Baragetti A, Norata GD.

Pol Arch Intern Med. 2017 Mar 31;127(3):152-153. doi: 10.20452/pamw.3989. Epub 2017 Mar 31. No abstract available.

23.

Vascular inflammation and low-density lipoproteins: is cholesterol the link? A lesson from the clinical trials.

Catapano AL, Pirillo A, Norata GD.

Br J Pharmacol. 2017 Nov;174(22):3973-3985. doi: 10.1111/bph.13805. Epub 2017 May 5. Review.

24.

Translating the microRNA signature of microvesicles derived from human coronary artery smooth muscle cells in patients with familial hypercholesterolemia and coronary artery disease.

de Gonzalo-Calvo D, Cenarro A, Garlaschelli K, Pellegatta F, Vilades D, Nasarre L, Camino-Lopez S, Crespo J, Carreras F, Leta R, Catapano AL, Norata GD, Civeira F, Llorente-Cortes V.

J Mol Cell Cardiol. 2017 May;106:55-67. doi: 10.1016/j.yjmcc.2017.03.005. Epub 2017 Mar 23.

PMID:
28342976
25.

T Follicular Helper Cells Promote a Beneficial Gut Ecosystem for Host Metabolic Homeostasis by Sensing Microbiota-Derived Extracellular ATP.

Perruzza L, Gargari G, Proietti M, Fosso B, D'Erchia AM, Faliti CE, Rezzonico-Jost T, Scribano D, Mauri L, Colombo D, Pellegrini G, Moregola A, Mooser C, Pesole G, Nicoletti M, Norata GD, Geuking MB, McCoy KD, Guglielmetti S, Grassi F.

Cell Rep. 2017 Mar 14;18(11):2566-2575. doi: 10.1016/j.celrep.2017.02.061.

26.

Translating the biology of adipokines in atherosclerosis and cardiovascular diseases: Gaps and open questions.

Ruscica M, Baragetti A, Catapano AL, Norata GD.

Nutr Metab Cardiovasc Dis. 2017 May;27(5):379-395. doi: 10.1016/j.numecd.2016.12.005. Epub 2016 Dec 23. Review.

PMID:
28237179
27.

Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals.

Mauro C, Smith J, Cucchi D, Coe D, Fu H, Bonacina F, Baragetti A, Cermenati G, Caruso D, Mitro N, Catapano AL, Ammirati E, Longhi MP, Okkenhaug K, Norata GD, Marelli-Berg FM.

Cell Metab. 2017 Mar 7;25(3):593-609. doi: 10.1016/j.cmet.2017.01.008. Epub 2017 Feb 9.

28.

Circulating CD14+ and CD14highCD16- classical monocytes are reduced in patients with signs of plaque neovascularization in the carotid artery.

Ammirati E, Moroni F, Magnoni M, Di Terlizzi S, Villa C, Sizzano F, Palini A, Garlaschelli K, Tripiciano F, Scotti I, Catapano AL, Manfredi AA, Norata GD, Camici PG.

Atherosclerosis. 2016 Dec;255:171-178. doi: 10.1016/j.atherosclerosis.2016.10.004. Epub 2016 Oct 6.

PMID:
27751505
29.

Epicardial Adipose Tissue (EAT) Thickness Is Associated with Cardiovascular and Liver Damage in Nonalcoholic Fatty Liver Disease.

Fracanzani AL, Pisano G, Consonni D, Tiraboschi S, Baragetti A, Bertelli C, Norata GD, Dongiovanni P, Valenti L, Grigore L, Tonella T, Catapano A, Fargion S.

PLoS One. 2016 Sep 14;11(9):e0162473. doi: 10.1371/journal.pone.0162473. eCollection 2016.

30.

Genetically determined telomeres shortening is associated with carotid atherosclerosis progression and increased incidence of cardiovascular events.

Baragetti A, Palmen J, Garlaschelli K, Grigore L, Humphries SE, Talmud PJ, Catapano AL, Norata GD.

Int J Cardiol. 2016 Nov 15;223:43-45. doi: 10.1016/j.ijcard.2016.08.164. Epub 2016 Aug 8. No abstract available.

PMID:
27532233
31.

Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering.

Norata GD, Tavori H, Pirillo A, Fazio S, Catapano AL.

Cardiovasc Res. 2016 Oct;112(1):429-42. doi: 10.1093/cvr/cvw194. Epub 2016 Aug 5. Review.

32.

Applicability of the 2013 ACC/AHA Risk Assessment and Cholesterol Treatment Guidelines in the real world: results from a multiethnic case-control study.

Magnoni M, Berteotti M, Norata GD, Limite LR, Peretto G, Cristell N, Maseri A, Cianflone D.

Ann Med. 2016;48(4):282-92. doi: 10.3109/07853890.2016.1168934. Epub 2016 Apr 7.

PMID:
27052543
33.

Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation.

Bonacina F, Barbieri SS, Cutuli L, Amadio P, Doni A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta. 2016 Jun;1862(6):1182-90. doi: 10.1016/j.bbadis.2016.03.007. Epub 2016 Mar 11.

34.

Niemann-Pick C1-Like 1 (NPC1L1) Inhibition and Cardiovascular Diseases.

Pirillo A, Catapano AL, Norata GD.

Curr Med Chem. 2016;23(10):983-99. Review.

35.

Subclinical atherosclerosis is associated with Epicardial Fat Thickness and hepatic steatosis in the general population.

Baragetti A, Pisano G, Bertelli C, Garlaschelli K, Grigore L, Fracanzani AL, Fargion S, Norata GD, Catapano AL.

Nutr Metab Cardiovasc Dis. 2016 Feb;26(2):141-53. doi: 10.1016/j.numecd.2015.10.013. Epub 2015 Nov 2.

PMID:
26777475
36.

Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin?

Liao X, Norata GD, Polak JF, Stehouwer CD, Catapano A, Rundek T, Ezhov M, Sander D, Thompson SG, Lorenz MW; PROG-IMT study group, Balakhonova T, Safarova M, Grigore L, Empana JP, Lin HJ, McLachlan S, Bokemark L, Ronkainen K, Schminke U, Lind L, Willeit P, Yanez DN, Steinmetz H, Poppert H, Desvarieux M, Ikram MA, Johnsen SH, Iglseder B, Friera A, Xie W, Plichart M, Su TC, Srinivasan SR, Schmidt C, Tuomainen TP, Völzke H, Nijpels G, Willeit J, Franco OH, Suarez C, Zhao D, Ducimetiere P, Chien KL, Robertson C, Bergström G, Kauhanen J, Dörr M, Dekker JM, Kiechl S, Sitzer M, Bickel H, Sacco RL, Hofman A, Mathiesen EB, Gabriel R, Liu J, Berenson G, Kavousi M, Price JF.

Eur J Prev Cardiol. 2016 Jul;23(11):1165-73. doi: 10.1177/2047487315625543. Epub 2016 Jan 8. Review.

PMID:
26746227
37.

Polymorphic Variants of SCN1A and EPHX1 Influence Plasma Carbamazepine Concentration, Metabolism and Pharmacoresistance in a Population of Kosovar Albanian Epileptic Patients.

Daci A, Beretta G, Vllasaliu D, Shala A, Govori V, Norata GD, Krasniqi S.

PLoS One. 2015 Nov 10;10(11):e0142408. doi: 10.1371/journal.pone.0142408. eCollection 2015.

38.

Apolipoprotein C-III: From Pathophysiology to Pharmacology.

Norata GD, Tsimikas S, Pirillo A, Catapano AL.

Trends Pharmacol Sci. 2015 Oct;36(10):675-687. doi: 10.1016/j.tips.2015.07.001. Review.

PMID:
26435212
39.

The Cellular and Molecular Basis of Translational Immunometabolism.

Norata GD, Caligiuri G, Chavakis T, Matarese G, Netea MG, Nicoletti A, O'Neill LA, Marelli-Berg FM.

Immunity. 2015 Sep 15;43(3):421-34. doi: 10.1016/j.immuni.2015.08.023. Review.

40.

Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant.

Boardman-Pretty F, Smith AJ, Cooper J, Palmen J, Folkersen L, Hamsten A, Catapano AL, Melander O, Price JF, Kumari M, Deanfield JE, Kivimäki M, Gertow K, Baragetti A, Norata GD, Humphries SE.

Circ Cardiovasc Genet. 2015 Oct;8(5):696-706. doi: 10.1161/CIRCGENETICS.115.001062. Epub 2015 Aug 14.

PMID:
26276885
41.

Carotid intima-media thickness progression and risk of vascular events in people with diabetes: results from the PROG-IMT collaboration.

Lorenz MW, Price JF, Robertson C, Bots ML, Polak JF, Poppert H, Kavousi M, Dörr M, Stensland E, Ducimetiere P, Ronkainen K, Kiechl S, Sitzer M, Rundek T, Lind L, Liu J, Bergström G, Grigore L, Bokemark L, Friera A, Yanez D, Bickel H, Ikram MA, Völzke H, Johnsen SH, Empana JP, Tuomainen TP, Willeit P, Steinmetz H, Desvarieux M, Xie W, Schmidt C, Norata GD, Suarez C, Sander D, Hofman A, Schminke U, Mathiesen E, Plichart M, Kauhanen J, Willeit J, Sacco RL, McLachlan S, Zhao D, Fagerberg B, Catapano AL, Gabriel R, Franco OH, Bülbül A, Scheckenbach F, Pflug A, Gao L, Thompson SG.

Diabetes Care. 2015 Oct;38(10):1921-9. doi: 10.2337/dc14-2732. Epub 2015 Jul 15. Review.

42.

PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling.

Braccini L, Ciraolo E, Campa CC, Perino A, Longo DL, Tibolla G, Pregnolato M, Cao Y, Tassone B, Damilano F, Laffargue M, Calautti E, Falasca M, Norata GD, Backer JM, Hirsch E.

Nat Commun. 2015 Jun 23;6:7400. doi: 10.1038/ncomms8400.

43.

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode.

Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I, Stravalaci M, Pasqualini F, Laface I, Valentino S, Tartari S, Ponzetta A, Maina V, Barbieri SS, Tremoli E, Catapano AL, Norata GD, Bottazzi B, Garlanda C, Mantovani A.

J Exp Med. 2015 Jun 1;212(6):905-25. doi: 10.1084/jem.20141268. Epub 2015 May 11.

44.

Markers of inflammation associated with plaque progression and instability in patients with carotid atherosclerosis.

Ammirati E, Moroni F, Norata GD, Magnoni M, Camici PG.

Mediators Inflamm. 2015;2015:718329. doi: 10.1155/2015/718329. Epub 2015 Apr 16. Review.

45.

IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population.

Dhyani A, Tibolla G, Baragetti A, Garlaschelli K, Pellegatta F, Grigore L, Norata GD, Catapano AL.

PLoS One. 2015 Apr 30;10(4):e0122414. doi: 10.1371/journal.pone.0122414. eCollection 2015.

46.

Fibronectin extra domain A stabilises atherosclerotic plaques in apolipoprotein E and in LDL-receptor-deficient mice.

Pulakazhi Venu VK, Uboldi P, Dhyani A, Patrini A, Baetta R, Ferri N, Corsini A, Muro AF, Catapano AL, Norata GD.

Thromb Haemost. 2015 Jul;114(1):186-97. doi: 10.1160/TH14-09-0790. Epub 2015 Apr 16.

PMID:
25881051
47.

Peak inflammation in atherosclerosis, primary biliary cirrhosis and autoimmune arthritis is counter-intuitively associated with regulatory T cell enrichment.

Garetto S, Trovato AE, Lleo A, Sala F, Martini E, Betz AG, Norata GD, Invernizzi P, Kallikourdis M.

Immunobiology. 2015 Aug;220(8):1025-9. doi: 10.1016/j.imbio.2015.02.006. Epub 2015 Feb 26.

48.

Homozygous familial hypobetalipoproteinemia: two novel mutations in the splicing sites of apolipoprotein B gene and review of the literature.

Cefalù AB, Norata GD, Ghiglioni DG, Noto D, Uboldi P, Garlaschelli K, Baragetti A, Spina R, Valenti V, Pederiva C, Riva E, Terracciano L, Zoja A, Grigore L, Averna MR, Catapano AL.

Atherosclerosis. 2015 Mar;239(1):209-17. doi: 10.1016/j.atherosclerosis.2015.01.014. Epub 2015 Jan 19. Review.

PMID:
25618028
49.

HDL in infectious diseases and sepsis.

Pirillo A, Catapano AL, Norata GD.

Handb Exp Pharmacol. 2015;224:483-508. doi: 10.1007/978-3-319-09665-0_15. Review.

50.

Impact of systemic inflammation and autoimmune diseases on apoA-I and HDL plasma levels and functions.

Montecucco F, Favari E, Norata GD, Ronda N, Nofer JR, Vuilleumier N.

Handb Exp Pharmacol. 2015;224:455-82. doi: 10.1007/978-3-319-09665-0_14. Review.

PMID:
25522998

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