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A Phase II Trial of Older Adults With Metastatic Breast Cancer Receiving nab-Paclitaxel: Melding the Fields of Geriatrics and Oncology.

Hurria A, Soto-Perez-de-Celis E, Blanchard S, Burhenn P, Yeon CH, Yuan Y, Li D, Katheria V, Waisman JR, Luu TH, Somlo G, Noonan AM, Lee T, Sudan N, Chung S, Rotter A, Arsenyan A, Levi A, Choi J, Rubalcava A, Morrison R, Mortimer JE.

Clin Breast Cancer. 2018 Oct 16. pii: S1526-8209(18)30328-8. doi: 10.1016/j.clbc.2018.10.002. [Epub ahead of print]


Circulating interleukin-6 is associated with disease progression, but not cachexia in pancreatic cancer.

Ramsey ML, Talbert E, Ahn D, Bekaii-Saab T, Badi N, Bloomston PM, Conwell DL, Cruz-Monserrate Z, Dillhoff M, Farren MR, Hinton A, Krishna SG, Lesinski GB, Mace T, Manilchuk A, Noonan A, Pawlik TM, Rajasekera PV, Schmidt C, Guttridge D, Hart PA.

Pancreatology. 2018 Nov 10. pii: S1424-3903(18)30747-6. doi: 10.1016/j.pan.2018.11.002. [Epub ahead of print]


LBA-002A phase 1b/II study of cancer stemness inhibitor napabucasin in combination with gemcitabine (gem) & nab-paclitaxel (nabptx) in metastatic pancreatic adenocarcinoma (mpdac) patients (pts).

Bekaii-Saab T, Starodub A, El-Rayes B, O'Neil B, Shahda S, Ciombor K, Noonan A, Hanna W, Sehdev A, Shaib W, Mikhail S, Neki A, Oh C, Li YZ, Li W, Borodyansky L, Li CJ.

Ann Oncol. 2017 Jun 1;28(suppl_3). doi: 10.1093/annonc/mdx302.001. No abstract available.


Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer.

Krishnamurthy A, Dasari A, Noonan AM, Mehnert JM, Lockhart AC, Leong S, Capasso A, Stein MN, Sanoff HK, Lee JJ, Hansen A, Malhotra U, Rippke S, Gustafson DL, Pitts TM, Ellison K, Davis SL, Messersmith WA, Eckhardt SG, Lieu CH.

Cancer Res. 2018 Sep 15;78(18):5398-5407. doi: 10.1158/0008-5472.CAN-18-0316. Epub 2018 Jul 24.


Impaired spatial processing in a mouse model of fragile X syndrome.

Ghilan M, Bettio LEB, Noonan A, Brocardo PS, Gil-Mohapel J, Christie BR.

Behav Brain Res. 2018 Sep 17;350:72-79. doi: 10.1016/j.bbr.2018.05.012. Epub 2018 May 17.


Factors Associated With Poor Sleep in Older Women Diagnosed With Breast Cancer.

Overcash J, Tan A, Patel K, Noonan AM.

Oncol Nurs Forum. 2018 May 1;45(3):359-371. doi: 10.1188/18.ONF.359-371.


Veterans' Preferences for Exchanging Information Using Veterans Affairs Health Information Technologies: Focus Group Results and Modeling Simulations.

Haun JN, Chavez M, Nazi K, Antinori N, Melillo C, Cotner BA, Hathaway W, Cook A, Wilck N, Noonan A.

J Med Internet Res. 2017 Oct 23;19(10):e359. doi: 10.2196/jmir.8614.


Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

Hart T, Tong AHY, Chan K, Van Leeuwen J, Seetharaman A, Aregger M, Chandrashekhar M, Hustedt N, Seth S, Noonan A, Habsid A, Sizova O, Nedyalkova L, Climie R, Tworzyanski L, Lawson K, Sartori MA, Alibeh S, Tieu D, Masud S, Mero P, Weiss A, Brown KR, Usaj M, Billmann M, Rahman M, Constanzo M, Myers CL, Andrews BJ, Boone C, Durocher D, Moffat J.

G3 (Bethesda). 2017 Aug 7;7(8):2719-2727. doi: 10.1534/g3.117.041277.


A modified regimen of biweekly gemcitabine and nab-paclitaxel in patients with metastatic pancreatic cancer is both tolerable and effective: a retrospective analysis.

Ahn DH, Krishna K, Blazer M, Reardon J, Wei L, Wu C, Ciombor KK, Noonan AM, Mikhail S, Bekaii-Saab T.

Ther Adv Med Oncol. 2017 Feb;9(2):75-82. doi: 10.1177/1758834016676011. Epub 2016 Nov 2.


The Effects of Ethanol Exposure During Distinct Periods of Brain Development on Oxidative Stress in the Adult Rat Brain.

Brocardo PS, Gil-Mohapel J, Wortman R, Noonan A, McGinnis E, Patten AR, Christie BR.

Alcohol Clin Exp Res. 2017 Jan;41(1):26-37. doi: 10.1111/acer.13266. Epub 2016 Nov 11.


Improving the health of African Americans in the USA: an overdue opportunity for social justice.

Noonan AS, Velasco-Mondragon HE, Wagner FA.

Public Health Rev. 2016 Oct 3;37:12. doi: 10.1186/s40985-016-0025-4. eCollection 2016. Review.


Next-generation sequencing survey of biliary tract cancer reveals the association between tumor somatic variants and chemotherapy resistance.

Ahn DH, Javle M, Ahn CW, Jain A, Mikhail S, Noonan AM, Ciombor K, Wu C, Shroff RT, Chen JL, Bekaii-Saab T.

Cancer. 2016 Dec 1;122(23):3657-3666. doi: 10.1002/cncr.30247. Epub 2016 Aug 6. Erratum in: Cancer. 2017 Jun 15;123(12 ):2376.


Characterization of ovarian cancer cell lines as in vivo models for preclinical studies.

Hernandez L, Kim MK, Lyle LT, Bunch KP, House CD, Ning F, Noonan AM, Annunziata CM.

Gynecol Oncol. 2016 Aug;142(2):332-40. doi: 10.1016/j.ygyno.2016.05.028. Epub 2016 May 28.


Cost description of chemotherapy regimens for the treatment of metastatic pancreas cancer.

Goldstein DA, Krishna K, Flowers CR, El-Rayes BF, Bekaii-Saab T, Noonan AM.

Med Oncol. 2016 May;33(5):48. doi: 10.1007/s12032-016-0762-8. Epub 2016 Apr 11.


Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma.

Noonan AM, Farren MR, Geyer SM, Huang Y, Tahiri S, Ahn D, Mikhail S, Ciombor KK, Pant S, Aparo S, Sexton J, Marshall JL, Mace TA, Wu CS, El-Rayes B, Timmers CD, Zwiebel J, Lesinski GB, Villalona-Calero MA, Bekaii-Saab TS.

Mol Ther. 2016 Jun;24(6):1150-1158. doi: 10.1038/mt.2016.66. Epub 2016 Apr 4.


Systemic Immune Activity Predicts Overall Survival in Treatment-Naïve Patients with Metastatic Pancreatic Cancer.

Farren MR, Mace TA, Geyer S, Mikhail S, Wu C, Ciombor K, Tahiri S, Ahn D, Noonan AM, Villalona-Calero M, Bekaii-Saab T, Lesinski GB.

Clin Cancer Res. 2016 May 15;22(10):2565-74. doi: 10.1158/1078-0432.CCR-15-1732. Epub 2015 Dec 30.


A dual role for Caspase8 and NF-κB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival.

Hernandez L, Kim MK, Noonan AM, Sagher E, Kohlhammer H, Wright G, Lyle LT, Steeg PS, Anver M, Bowtell DD; Australian Ovarian Cancer Study Group 57, Annunziata CM.

Cell Death Discov. 2015 Dec 14;1:15053. doi: 10.1038/cddiscovery.2015.53. eCollection 2015.


Pharmacodynamic markers and clinical results from the phase 2 study of the SMAC mimetic birinapant in women with relapsed platinum-resistant or -refractory epithelial ovarian cancer.

Noonan AM, Bunch KP, Chen JQ, Herrmann MA, Lee JM, Kohn EC, O'Sullivan CC, Jordan E, Houston N, Takebe N, Kinders RJ, Cao L, Peer CJ, Figg WD, Annunziata CM.

Cancer. 2016 Feb 15;122(4):588-597. doi: 10.1002/cncr.29783. Epub 2015 Nov 13.


Upfront molecular testing in patients with advanced gastro-esophageal cancer: Is it time yet?

Mikhail S, Ciombor K, Noonan A, Wu C, Goldberg R, Zhao W, Wei L, Mathey K, Yereb M, Timmers C, Bekaii-Saab T.

Oncotarget. 2015 Sep 8;6(26):22206-13.


Using optical coherence tomography to rapidly phenotype and quantify congenital heart defects associated with prenatal alcohol exposure.

Karunamuni G, Gu S, Doughman YQ, Noonan AI, Rollins AM, Jenkins MW, Watanabe M.

Dev Dyn. 2015 Apr;244(4):607-18. doi: 10.1002/dvdy.24246. Epub 2015 Mar 13.


Second-line outcomes in metastatic colorectal cancer--raising the bar for the high jump rather than the doing the limbo.

Noonan AM, Bekaii-Saab T.

Expert Rev Pharmacoecon Outcomes Res. 2015 Feb;15(1):133-43. doi: 10.1586/14737167.2015.972376. Epub 2014 Dec 3. Review.


Integrative advances for OCT-guided ophthalmic surgery and intraoperative OCT: microscope integration, surgical instrumentation, and heads-up display surgeon feedback.

Ehlers JP, Srivastava SK, Feiler D, Noonan AI, Rollins AM, Tao YK.

PLoS One. 2014 Aug 20;9(8):e105224. doi: 10.1371/journal.pone.0105224. eCollection 2014.


Phase I/Ib study of olaparib and carboplatin in BRCA1 or BRCA2 mutation-associated breast or ovarian cancer with biomarker analyses.

Lee JM, Hays JL, Annunziata CM, Noonan AM, Minasian L, Zujewski JA, Yu M, Gordon N, Ji J, Sissung TM, Figg WD, Azad N, Wood BJ, Doroshow J, Kohn EC.

J Natl Cancer Inst. 2014 May 19;106(6):dju089. doi: 10.1093/jnci/dju089. Print 2014 Jun.


Adaptive response to sociality and ecology drives the diversification of facial colour patterns in catarrhines.

Santana SE, Alfaro JL, Noonan A, Alfaro ME.

Nat Commun. 2013;4:2765. doi: 10.1038/ncomms3765.


Reasons identified for seeking the American Physical Therapy Association-Credentialed Clinical Instructor Program (CCIP) in Florida.

Musolino GM, van Duijn J, Noonan AC, Eargle LK, Gray DL.

J Allied Health. 2013 Fall;42(3):e51-60.


Impairments in hippocampal synaptic plasticity following prenatal ethanol exposure are dependent on glutathione levels.

Patten AR, Brocardo PS, Sakiyama C, Wortman RC, Noonan A, Gil-Mohapel J, Christie BR.

Hippocampus. 2013 Dec;23(12):1463-75. doi: 10.1002/hipo.22199. Epub 2013 Oct 1.


Adolescents' religious discordance with mothers: is there a connection to sexual risk behavior during emerging adulthood?

Grossman JM, Tracy AJ, Noonan AE.

J Prim Prev. 2013 Oct;34(5):329-43. doi: 10.1007/s10935-013-0315-2.


Deleterious BRCA1/2 mutation is an independent risk factor for carboplatin hypersensitivity reactions.

Moon DH, Lee JM, Noonan AM, Annunziata CM, Minasian L, Houston N, Hays JL, Kohn EC.

Br J Cancer. 2013 Aug 20;109(4):1072-8. doi: 10.1038/bjc.2013.389. Epub 2013 Jul 18.


Electrocardiographic studies of romidepsin demonstrate its safety and identify a potential role for K(ATP) channel.

Noonan AM, Eisch RA, Liewehr DJ, Sissung TM, Venzon DJ, Flagg TP, Haigney MC, Steinberg SM, Figg WD, Piekarz RL, Bates SE.

Clin Cancer Res. 2013 Jun 1;19(11):3095-104. doi: 10.1158/1078-0432.CCR-13-0109. Epub 2013 Apr 15.


Feasibility and safety of sequential research-related tumor core biopsies in clinical trials.

Lee JM, Hays JL, Noonan AM, Squires J, Minasian L, Annunziata C, Wood BJ, Yu M, Calvo KR, Houston N, Azad N, Kohn EC.

Cancer. 2013 Apr 1;119(7):1357-64. doi: 10.1002/cncr.27916. Epub 2012 Dec 20.


Effects of Ethanol Exposure during Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity.

Patten AR, Gil-Mohapel J, Wortman RC, Noonan A, Brocardo PS, Christie BR.

Brain Sci. 2013 Jul 19;3(3):1076-94. doi: 10.3390/brainsci3031076.


RECIST: no longer the sharpest tool in the oncology clinical trials toolbox--reply to point.

Fojo AT, Noonan A.

Cancer Res. 2012 Oct 15;72(20):5150. doi: 10.1158/0008-5472.CAN-12-1989. Epub 2012 Sep 4. No abstract available.


Why RECIST works and why it should stay--counterpoint.

Fojo AT, Noonan A.

Cancer Res. 2012 Oct 15;72(20):5151-7; discussion 5158. doi: 10.1158/0008-5472.CAN-12-0733. Epub 2012 Sep 4.


IKK-ε coordinates invasion and metastasis of ovarian cancer.

Hsu S, Kim M, Hernandez L, Grajales V, Noonan A, Anver M, Davidson B, Annunziata CM.

Cancer Res. 2012 Nov 1;72(21):5494-504. doi: 10.1158/0008-5472.CAN-11-3993. Epub 2012 Aug 31.


The role of historically black colleges and universities in training the health care workforce.

Noonan A, Lindong I, Jaitley VN.

Am J Public Health. 2013 Mar;103(3):412-5. doi: 10.2105/AJPH.2012.300726. Epub 2012 Aug 16.


Correlates of age at diagnosis of autism spectrum disorders in six Canadian regions.

Coo H, Ouellette-Kuntz H, Lam M, Yu CT, Dewey D, Bernier FP, Chudley AE, Hennessey PE, Breitenbach MM, Noonan AL, Lewis ME, Holden JJ.

Chronic Dis Inj Can. 2012 Mar;32(2):90-100.


Framing the research agenda for sickle cell trait: building on the current understanding of clinical events and their potential implications.

Goldsmith JC, Bonham VL, Joiner CH, Kato GJ, Noonan AS, Steinberg MH.

Am J Hematol. 2012 Mar;87(3):340-6. doi: 10.1002/ajh.22271. Epub 2012 Feb 3.


Psychotherapy training in Ireland: A survey of college tutors.

Lee A, Noonan A.

Ir J Psychol Med. 2012 Jan;29(1):41-45. doi: 10.1017/S0790966700017602.


Frequency and outcome of neoplastic brachial plexopathy: single institution experience.

Noonan AM, McCaffrey J.

Ir Med J. 2011 Mar;104(3):76-8.


Use of seclusion in a general hospital acute psychiatric unit.

Prinsloo B, Noonan A.

Ir J Psychol Med. 2010 Dec;27(4):184-188. doi: 10.1017/S079096670000149X.


Using live tissue laboratories to promote clinical reasoning in doctor of physical therapy students.

Moore WA, Noonan AC.

Adv Physiol Educ. 2010 Jun;34(2):54-8. doi: 10.1152/advan.00059.2009.


A call to action: developing and implementing a national action plan to improve bone health.

Raisz LG, Elderkin AL, Schargorodski L, Hart T, Waldman C, King T, Noonan AS.

Osteoporos Int. 2009 Nov;20(11):1805-6. doi: 10.1007/s00198-009-1041-8. No abstract available.


Age at diagnosis of autism spectrum disorders in four regions of Canada.

Ouellette-Kuntz HM, Coo H, Lam M, Yu CT, Breitenbach MM, Hennessey PE, Holden JJ, Brown HK, Noonan AL, Gauthier RB, Crews LR.

Can J Public Health. 2009 Jul-Aug;100(4):268-73.


Drug users' failure to modify alcohol consumption in response to hepatitis C.

Noonan A, Kavanagh P, Sweeney B.

Ir J Psychol Med. 2009 Mar;26(1):27-31. doi: 10.1017/S0790966700000100.


Alpha-fetoprotein and human chorionic gonadotrophin-beta as prognostic markers in neuroendocrine tumour patients.

Shah T, Srirajaskanthan R, Bhogal M, Toubanakis C, Meyer T, Noonan A, Witney-Smith C, Amin T, Bhogal P, Sivathasan N, Warner B, Hochhauser D, Caplin ME.

Br J Cancer. 2008 Jul 8;99(1):72-7. doi: 10.1038/sj.bjc.6604428. Epub 2008 Jun 24.


Occupational contact urticaria: Australian data.

Williams JD, Lee AY, Matheson MC, Frowen KE, Noonan AM, Nixon RL.

Br J Dermatol. 2008 Jul;159(1):125-31. doi: 10.1111/j.1365-2133.2008.08583.x. Epub 2008 Jul 1.


Occupational contact dermatitis in Australia: diagnostic and management practices, and severity of worker impairment.

Keegel T, Erbas B, Cahill J, Noonan A, Dharmage S, Nixon R.

Contact Dermatitis. 2007 Jun;56(6):318-24.


Skin care in occupational contact dermatitis of the hands.

Moyle M, Keegel T, Noonan A, Nixon R.

Australas J Dermatol. 2006 May;47(2):97-101.


Nurses and occupational contact dermatitis.

Noonan A, Moyle M.

Aust Nurs J. 2005 Jun;12(11):29-31. Review. No abstract available.


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