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Items: 44


Single-cell RNA-Seq analysis identifies a putative epithelial stem cell population in human primary prostate cells in monolayer and organoid culture conditions.

McCray T, Moline D, Baumann B, Vander Griend DJ, Nonn L.

Am J Clin Exp Urol. 2019 Jun 15;7(3):123-138. eCollection 2019.


High levels of PIWI-interacting RNAs are present in the small RNA landscape of prostate epithelium from vitamin D clinical trial specimens.

Baumann B, Lugli G, Gao S, Zenner M, Nonn L.

Prostate. 2019 Jun;79(8):840-855. doi: 10.1002/pros.23789. Epub 2019 Mar 24.


Genetic Ancestry Analysis Reveals Misclassification of Commonly Used Cancer Cell Lines.

Hooker SE Jr, Woods-Burnham L, Bathina M, Lloyd S, Gorjala P, Mitra R, Nonn L, Kimbro KS, Kittles RA.

Cancer Epidemiol Biomarkers Prev. 2019 Jun;28(6):1003-1009. doi: 10.1158/1055-9965.EPI-18-1132. Epub 2019 Feb 20.


Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids.

Richards Z, McCray T, Marsili J, Zenner ML, Manlucu JT, Garcia J, Kajdacsy-Balla A, Murray M, Voisine C, Murphy AB, Abdulkadir SA, Prins GS, Nonn L.

iScience. 2019 Feb 22;12:304-317. doi: 10.1016/j.isci.2019.01.028. Epub 2019 Jan 23.


Handling and Assessment of Human Primary Prostate Organoid Culture.

McCray T, Richards Z, Marsili J, Prins GS, Nonn L.

J Vis Exp. 2019 Jan 17;(143). doi: 10.3791/59051.


Association of High miR-182 Levels with Low-Risk Prostate Cancer.

Baumann B, Acosta AM, Richards Z, Deaton R, Sapatynska A, Murphy A, Kajdacsy-Balla A, Gann PH, Nonn L.

Am J Pathol. 2019 Apr;189(4):911-923. doi: 10.1016/j.ajpath.2018.12.014. Epub 2019 Jan 29.


GPX1 Localizes to the Nucleus in Prostate Epithelium and its Levels are not Associated with Prostate Cancer Recurrence.

Ekoue DN, Ansong E, Hong LK, Nonn L, Macias V, Deaton R, Rupnow R, Gann PH, Kajdacsy-Balla A, Diamond AM.

Antioxidants (Basel). 2018 Nov 18;7(11). pii: E167. doi: 10.3390/antiox7110167.


Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer.

Kumar B, Rosenberg AZ, Choi SM, Fox-Talbot K, De Marzo AM, Nonn L, Brennen WN, Marchionni L, Halushka MK, Lupold SE.

Sci Rep. 2018 May 8;8(1):7189. doi: 10.1038/s41598-018-25320-z.


Correlations of SELENOF and SELENOP genotypes with serum selenium levels and prostate cancer.

Ekoue DN, Ansong E, Liu L, Macias V, Deaton R, Lacher C, Picklo M, Nonn L, Gann PH, Kajdacsy-Balla A, Prins GS, Freeman VL, Diamond AM.

Prostate. 2018 Mar;78(4):279-288. doi: 10.1002/pros.23471. Epub 2018 Jan 5.


Organoids model distinct Vitamin E effects at different stages of prostate cancer evolution.

Njoroge RN, Unno K, Zhao JC, Naseem AF, Anker JF, McGee WA, Nonn L, Abdulkadir SA.

Sci Rep. 2017 Nov 24;7(1):16285. doi: 10.1038/s41598-017-16459-2.


Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids.

Unno K, Roh M, Yoo YA, Al-Shraideh Y, Wang L, Nonn L, Abdulkadir SA.

Oncotarget. 2017 Apr 19;8(31):51264-51276. doi: 10.18632/oncotarget.17230. eCollection 2017 Aug 1.


The miR-183 family cluster alters zinc homeostasis in benign prostate cells, organoids and prostate cancer xenografts.

Dambal S, Baumann B, McCray T, Williams L, Richards Z, Deaton R, Prins GS, Nonn L.

Sci Rep. 2017 Aug 9;7(1):7704. doi: 10.1038/s41598-017-07979-y.


Isolation and functional interrogation of adult human prostate epithelial stem cells at single cell resolution.

Hu WY, Hu DP, Xie L, Li Y, Majumdar S, Nonn L, Hu H, Shioda T, Prins GS.

Stem Cell Res. 2017 Aug;23:1-12. doi: 10.1016/j.scr.2017.06.009. Epub 2017 Jun 16.


Prostatic compensation of the vitamin D axis in African American men.

Richards Z, Batai K, Farhat R, Shah E, Makowski A, Gann PH, Kittles R, Nonn L.

JCI Insight. 2017 Jan 26;2(2):e91054. doi: 10.1172/jci.insight.91054.


microRNAs and DICER1 are regulated by 1,25-dihydroxyvitamin D in prostate stroma.

Dambal S, Giangreco AA, Acosta AM, Fairchild A, Richards Z, Deaton R, Wagner D, Vieth R, Gann PH, Kajdacsy-Balla A, Van der Kwast T, Nonn L.

J Steroid Biochem Mol Biol. 2017 Mar;167:192-202. doi: 10.1016/j.jsbmb.2017.01.004. Epub 2017 Jan 12.


Vitamin D and Immune Response: Implications for Prostate Cancer in African Americans.

Batai K, Murphy AB, Nonn L, Kittles RA.

Front Immunol. 2016 Feb 22;7:53. doi: 10.3389/fimmu.2016.00053. eCollection 2016. Review.


Laser-capture Microdissection of Human Prostatic Epithelium for RNA Analysis.

Lugli G, Kataria Y, Richards Z, Gann P, Zhou X, Nonn L.

J Vis Exp. 2015 Nov 26;(105). doi: 10.3791/53405.


A Phase II Randomized Trial of Lycopene-Rich Tomato Extract Among Men with High-Grade Prostatic Intraepithelial Neoplasia.

Gann PH, Deaton RJ, Rueter EE, van Breemen RB, Nonn L, Macias V, Han M, Ananthanarayanan V.

Nutr Cancer. 2015;67(7):1104-12. doi: 10.1080/01635581.2015.1075560.


The microRNA-183 cluster: the family that plays together stays together.

Dambal S, Shah M, Mihelich B, Nonn L.

Nucleic Acids Res. 2015 Sep 3;43(15):7173-88. doi: 10.1093/nar/gkv703. Epub 2015 Jul 13. Review.


Elevated serum microRNA levels associate with absence of high-grade prostate cancer in a retrospective cohort.

Mihelich BL, Maranville JC, Nolley R, Peehl DM, Nonn L.

PLoS One. 2015 Apr 14;10(4):e0124245. doi: 10.1371/journal.pone.0124245. eCollection 2015.


Differential expression and regulation of vitamin D hydroxylases and inflammatory genes in prostate stroma and epithelium by 1,25-dihydroxyvitamin D in men with prostate cancer and an in vitro model.

Giangreco AA, Dambal S, Wagner D, Van der Kwast T, Vieth R, Prins GS, Nonn L.

J Steroid Biochem Mol Biol. 2015 Apr;148:156-65. doi: 10.1016/j.jsbmb.2014.10.004. Epub 2014 Oct 8.


Inhibition of CHOP accentuates the apoptotic effect of α-mangostin from the mangosteen fruit (Garcinia mangostana) in 22Rv1 prostate cancer cells.

Li G, Petiwala SM, Nonn L, Johnson JJ.

Biochem Biophys Res Commun. 2014 Oct 10;453(1):75-80. doi: 10.1016/j.bbrc.2014.09.054. Epub 2014 Sep 26.


Rosemary (Rosmarinus officinalis) extract modulates CHOP/GADD153 to promote androgen receptor degradation and decreases xenograft tumor growth.

Petiwala SM, Berhe S, Li G, Puthenveetil AG, Rahman O, Nonn L, Johnson JJ.

PLoS One. 2014 Mar 5;9(3):e89772. doi: 10.1371/journal.pone.0089772. eCollection 2014.


Selective modulation of endoplasmic reticulum stress markers in prostate cancer cells by a standardized mangosteen fruit extract.

Li G, Petiwala SM, Pierce DR, Nonn L, Johnson JJ.

PLoS One. 2013 Dec 18;8(12):e81572. doi: 10.1371/journal.pone.0081572. eCollection 2013.


Tumor suppressor microRNAs, miR-100 and -125b, are regulated by 1,25-dihydroxyvitamin D in primary prostate cells and in patient tissue.

Giangreco AA, Vaishnav A, Wagner D, Finelli A, Fleshner N, Van der Kwast T, Vieth R, Nonn L.

Cancer Prev Res (Phila). 2013 May;6(5):483-94. doi: 10.1158/1940-6207.CAPR-12-0253. Epub 2013 Mar 15.


Effects of lycopene on protein expression in human primary prostatic epithelial cells.

Qiu X, Yuan Y, Vaishnav A, Tessel MA, Nonn L, van Breemen RB.

Cancer Prev Res (Phila). 2013 May;6(5):419-27. doi: 10.1158/1940-6207.CAPR-12-0364. Epub 2013 Mar 12.


Randomized clinical trial of vitamin D3 doses on prostatic vitamin D metabolite levels and ki67 labeling in prostate cancer patients.

Wagner D, Trudel D, Van der Kwast T, Nonn L, Giangreco AA, Li D, Dias A, Cardoza M, Laszlo S, Hersey K, Klotz L, Finelli A, Fleshner N, Vieth R.

J Clin Endocrinol Metab. 2013 Apr;98(4):1498-507. doi: 10.1210/jc.2012-4019. Epub 2013 Mar 5.


The sum of many small changes: microRNAs are specifically and potentially globally altered by vitamin D3 metabolites.

Giangreco AA, Nonn L.

J Steroid Biochem Mol Biol. 2013 Jul;136:86-93. doi: 10.1016/j.jsbmb.2013.01.001. Epub 2013 Jan 16. Review.


miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells.

Mihelich BL, Khramtsova EA, Arva N, Vaishnav A, Johnson DN, Giangreco AA, Martens-Uzunova E, Bagasra O, Kajdacsy-Balla A, Nonn L.

J Biol Chem. 2011 Dec 30;286(52):44503-11. doi: 10.1074/jbc.M111.262915. Epub 2011 Nov 1.


Gene expression patterns in the human breast after pregnancy.

Asztalos S, Gann PH, Hayes MK, Nonn L, Beam CA, Dai Y, Wiley EL, Tonetti DA.

Cancer Prev Res (Phila). 2010 Mar;3(3):301-11. doi: 10.1158/1940-6207.CAPR-09-0069. Epub 2010 Feb 23.


mRNA and micro-RNA expression analysis in laser-capture microdissected prostate biopsies: valuable tool for risk assessment and prevention trials.

Nonn L, Vaishnav A, Gallagher L, Gann PH.

Exp Mol Pathol. 2010 Feb;88(1):45-51. doi: 10.1016/j.yexmp.2009.10.005. Epub 2009 Oct 27.


Evidence for field cancerization of the prostate.

Nonn L, Ananthanarayanan V, Gann PH.

Prostate. 2009 Sep 15;69(13):1470-9. doi: 10.1002/pros.20983. Review.


Calcitriol as a chemopreventive and therapeutic agent in prostate cancer: role of anti-inflammatory activity.

Krishnan AV, Moreno J, Nonn L, Swami S, Peehl DM, Feldman D.

J Bone Miner Res. 2007 Dec;22 Suppl 2:V74-80. doi: 10.1359/jbmr.07s213. Review.


Novel pathways that contribute to the anti-proliferative and chemopreventive activities of calcitriol in prostate cancer.

Krishnan AV, Moreno J, Nonn L, Malloy P, Swami S, Peng L, Peehl DM, Feldman D.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):694-702. Epub 2007 Jan 16.


Tumor-selective killing by selenite in patient-matched pairs of normal and malignant prostate cells.

Husbeck B, Nonn L, Peehl DM, Knox SJ.

Prostate. 2006 Feb 1;66(2):218-25.


Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells.

Moreno J, Krishnan AV, Swami S, Nonn L, Peehl DM, Feldman D.

Cancer Res. 2005 Sep 1;65(17):7917-25.


Molecular activity of 1,25-dihydroxyvitamin D3 in primary cultures of human prostatic epithelial cells revealed by cDNA microarray analysis.

Peehl DM, Shinghal R, Nonn L, Seto E, Krishnan AV, Brooks JD, Feldman D.

J Steroid Biochem Mol Biol. 2004 Oct;92(3):131-41.


Molecular targets of doxazosin in human prostatic stromal cells.

Zhao H, Lai F, Nonn L, Brooks JD, Peehl DM.

Prostate. 2005 Mar 1;62(4):400-10.


Mechanisms of decreased Vitamin D 1alpha-hydroxylase activity in prostate cancer cells.

Ma JF, Nonn L, Campbell MJ, Hewison M, Feldman D, Peehl DM.

Mol Cell Endocrinol. 2004 Jun 30;221(1-2):67-74.


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