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Decreased H3K27me3 Expression Is Associated With Merkel Cell Polyomavirus-negative Merkel Cell Carcinoma, Especially Combined With Cutaneous Squamous Cell Carcinoma.

Matsushita M, Iwasaki T, Wardhani LO, Kuwamoto S, Nonaka D, Nagata K, Kato M, Kitamura Y, Hayashi K.

Anticancer Res. 2019 Oct;39(10):5573-5579. doi: 10.21873/anticanres.13751.


Is the place of birth related to the mother's satisfaction with childbirth? A cross-sectional study in a rural district of the Lao People's Democratic Republic (Lao PDR).

Takayama T, Phongluxa K, Nonaka D, Sato C, Gregorio ER Jr, Inthavong N, Pongvongsa T, Kounnavong S, Kobayashi J.

BMC Pregnancy Childbirth. 2019 Sep 11;19(1):333. doi: 10.1186/s12884-019-2483-4.


Capecitabine and temozolomide in patients with advanced pulmonary carcinoid tumours.

Papaxoinis G, Kordatou Z, McCallum L, Nasralla M, Lamarca A, Backen A, Nonaka D, Mansoor W.

Neuroendocrinology. 2019 Aug 23. doi: 10.1159/000502864. [Epub ahead of print]


Intraventricular thrombus and severe mitral regurgitation in the acute phase of takotsubo cardiomyopathy: two case reports.

Nonaka D, Takase H, Machii M, Ohno K.

J Med Case Rep. 2019 May 19;13(1):152. doi: 10.1186/s13256-019-2081-0.


Suicidal ideation, suicidal behaviors, and attitudes towards suicide of adolescents enrolled in the Alternative Learning System in Manila, Philippines-a mixed methods study.

Estrada CAM, Nonaka D, Gregorio ER Jr, Leynes CR, Del Castillo RT, Hernandez PMR, Hayakawa T, Kobayashi J.

Trop Med Health. 2019 Mar 29;47:22. doi: 10.1186/s41182-019-0149-6. eCollection 2019.


Genomic Evaluation of Multiparametric Magnetic Resonance Imaging-visible and -nonvisible Lesions in Clinically Localised Prostate Cancer.

Parry MA, Srivastava S, Ali A, Cannistraci A, Antonello J, Barros-Silva JD, Ubertini V, Ramani V, Lau M, Shanks J, Nonaka D, Oliveira P, Hambrock T, Leong HS, Dhomen N, Miller C, Brady G, Dive C, Clarke NW, Marais R, Baena E.

Eur Urol Oncol. 2019 Feb;2(1):1-11. doi: 10.1016/j.euo.2018.08.005. Epub 2018 Sep 5.


When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?

Baird AM, Easty D, Jarzabek M, Shiels L, Soltermann A, Klebe S, Raeppel S, MacDonagh L, Wu C, Griggs K, Kirschner MB, Stanfill B, Nonaka D, Goparaju CM, Murer B, Fennell DA, O'Donnell DM, Barr MP, Mutti L, Reid G, Finn S, Cuffe S, Pass HI, Opitz I, Byrne AT, O'Byrne KJ, Gray SG.

Front Endocrinol (Lausanne). 2019 Feb 26;10:89. doi: 10.3389/fendo.2019.00089. eCollection 2019.


Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People's Democratic Republic.

Kaneshiro Y, Sourinphoumy K, Imaizumi N, Rasaphon M, Kuba-Miyara M, Sakihama S, Guerrero CLH, Nhativong K, Nonaka D, Pongvongsa T, Kobayashi J, Kounnavong S, Fukushima T.

Trop Med Health. 2019 Feb 11;47:14. doi: 10.1186/s41182-019-0142-0. eCollection 2019.


Malaria prevalence, knowledge, perception, preventive and treatment behavior among military in Champasak and Attapeu provinces, Lao PDR: a mixed methods study.

Vilay P, Nonaka D, Senamonty P, Lao M, Iwagami M, Kobayashi J, Hernandez PM, Phrasisombath K, Kounnavong S, Hongvanthong B, Brey PT, Kano S.

Trop Med Health. 2019 Jan 25;47:11. doi: 10.1186/s41182-019-0138-9. eCollection 2019.


Malaria among foreign migrant workers in Savannakhet Province, Lao People's Democratic Republic.

Pongvongsa T, Nonaka D, Iwagami M, Soundala P, Khattignavong P, Xangsayarath P, Nishimoto F, Kobayashi J, Hongvanthon B, Brey PT, Kano S.

Trop Med Health. 2019 Jan 25;47:10. doi: 10.1186/s41182-019-0140-2. eCollection 2019.


Oral health behavior of children and guardians' beliefs about children's dental caries in Vientiane, Lao People's Democratic Republic (Lao PDR).

Phanthavong S, Nonaka D, Phonaphone T, Kanda K, Sombouaphan P, Wake N, Sayavong S, Nakasone T, Phongsavath K, Arasaki A.

PLoS One. 2019 Jan 25;14(1):e0211257. doi: 10.1371/journal.pone.0211257. eCollection 2019.


Quality of public school toilets and the frequency of changing sanitary napkins among students in public secondary schools in the City of Manila, Philippines.

Katsuno C, Gregorio ER Jr, Lomboy MFTC, Nonaka D, Hernandez PMR, Estrada CAM, Pimentel JMT, Bernadas RMGC, Kobayashi J.

Trop Med Health. 2019 Jan 11;47:5. doi: 10.1186/s41182-018-0131-8. eCollection 2019.


Patients' adherence to artemisinin-based combination therapy and healthcare workers' perception and practice in Savannakhet province, Lao PDR.

Takahashi E, Nonaka D, Iwagami M, Phoutnalong V, Chanthakoumane K, Kobayashi J, Pongvongsa T, Kounnavong S, Hongvanthong B, Brey PT, Kano S.

Trop Med Health. 2018 Dec 22;46:44. doi: 10.1186/s41182-018-0125-6. eCollection 2018.


Expression of Notch 3 and Jagged 1 Is Associated With Merkel Cell Polyomavirus Status and Prognosis in Merkel Cell Carcinoma.

Wardhani LO, Matsushita M, Kuwamoto S, Nonaka D, Nagata K, Kato M, Kitamura Y, Hayashi K.

Anticancer Res. 2019 Jan;39(1):319-329. doi: 10.21873/anticanres.13114.


Implementation of disaster risk reduction and management policies in a school setting in Lao PDR: a case study.

Kanyasan K, Nonaka D, Chatouphonexay A, Hernandez PM, Kounnavong S, Kobayashi J.

Trop Med Health. 2018 Dec 12;46:42. doi: 10.1186/s41182-018-0124-7. eCollection 2018.


Identification of the salusin-β receptor using proteoliposomes embedded with endogenous membrane proteins.

Shichiri M, Nonaka D, Lee LJ, Tanaka K.

Sci Rep. 2018 Dec 14;8(1):17865. doi: 10.1038/s41598-018-35740-6.


New Biomarkers for Prediction of Disseminated Intravascular Coagulation in Patients With Sepsis.

Wakabayashi I, Mambo N, Ueda T, Nonaka D, Lee LJ, Tanaka K, Kotani J.

Clin Appl Thromb Hemost. 2018 Oct 10:1076029618804078. doi: 10.1177/1076029618804078. [Epub ahead of print]


Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort.

Rulle U, Tsourti Z, Casanova R, Deml KF, Verbeken E, Thunnissen E, Warth A, Cheney R, Sejda A, Speel EJ, Madsen LB, Nonaka D, Navarro A, Sansano I, Marchetti A, Finn SP, Monkhorst K, Kerr KM, Haberecker M, Wu C, Zygoura P, Kammler R, Geiger T, Gendreau S, Schulze K, Vrugt B, Wild P, Moch H, Weder W, Ciftlik AT, Dafni U, Peters S, Bubendorf L, Stahel RA, Soltermann A.

J Thorac Oncol. 2018 Dec;13(12):1851-1863. doi: 10.1016/j.jtho.2018.08.2034. Epub 2018 Sep 18.


Expression of the IDO1/TDO2-AhR pathway in tumor cells or the tumor microenvironment is associated with Merkel cell polyomavirus status and prognosis in Merkel cell carcinoma.

Wardhani LO, Matsushita M, Iwasaki T, Kuwamoto S, Nonaka D, Nagata K, Kato M, Kitamura Y, Hayashi K.

Hum Pathol. 2019 Feb;84:52-61. doi: 10.1016/j.humpath.2018.09.003. Epub 2018 Sep 18.


Ischemic Mitral Regurgitation: Repair, Replacement or Nothing.

Nonaka DF, Fox AA.

Semin Cardiothorac Vasc Anesth. 2019 Mar;23(1):11-19. doi: 10.1177/1089253218792921. Epub 2018 Aug 13. Review.


Effect of combined therapy with catheter-directed thrombolysis and factor Xa inhibitor for inferior vena cava thrombosis: A case report.

Nonaka D, Takase H, Machii M, Ohno K.

Medicine (Baltimore). 2018 Jul;97(28):e11221. doi: 10.1097/MD.0000000000011221.


Percutaneous Pulmonary Vein Stent Placement Guided by 2- and 3-Dimensional Transesophageal Echocardiography: A Case Report.

Nonaka DF, Gualano SK, Nugent AW, Fox AA.

A A Pract. 2018 Jun 15;10(12):327-330. doi: 10.1213/XAA.0000000000000708. No abstract available.


Clinical and Pathologic Characteristics of Pulmonary Carcinoid Tumors in Central and Peripheral Locations.

Papaxoinis G, Lamarca A, Quinn AM, Mansoor W, Nonaka D.

Endocr Pathol. 2018 Sep;29(3):259-268. doi: 10.1007/s12022-018-9530-y.


Gastrointestinal Stromal Tumor With Multiple Primary Tyrosine Kinase Mutations-Clinicopathologic and Molecular Characterization.

Wong NACS, Taniere P, Walsh S, Wallace A, Nonaka D, Jones T, Gonzalez D.

Appl Immunohistochem Mol Morphol. 2019 Jul;27(6):461-465. doi: 10.1097/PAI.0000000000000660.


PD-L1 expression and presence of TILs in small intestinal neuroendocrine tumours.

Lamarca A, Nonaka D, Breitwieser W, Ashton G, Barriuso J, McNamara MG, Moghadam S, Rogan J, Mansoor W, Hubner RA, Clark C, Chakrabarty B, Valle JW.

Oncotarget. 2018 Feb 12;9(19):14922-14938. doi: 10.18632/oncotarget.24464. eCollection 2018 Mar 13.


Circulating odd-chain saturated fatty acids were associated with arteriosclerosis among patients with diabetes, dyslipidemia, or hypertension in Sri Lanka but not Japan.

Kurotani K, Karunapema P, Jayaratne K, Sato M, Hayashi T, Kajio H, Fukuda S, Hara H, Okazaki O, Jayatilleke AU, Nonaka D, Noda M, Mizoue T.

Nutr Res. 2018 Feb;50:82-93. doi: 10.1016/j.nutres.2017.12.004. Epub 2017 Dec 17.


Selected reaction monitoring for colorectal cancer diagnosis using a set of five serum peptides identified by BLOTCHIP®-MS analysis.

Uchiyama K, Naito Y, Yagi N, Mizushima K, Higashimura Y, Hirai Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Nonaka D, Asada K, Lee LJ, Tanaka K, Kuriu Y, Nakanishi M, Otsuji E, Itoh Y.

J Gastroenterol. 2018 Nov;53(11):1179-1185. doi: 10.1007/s00535-018-1448-0. Epub 2018 Mar 1.


Recent changes in blood pressure levels, hypertension prevalence and treatment rates, and the rate of reaching target blood pressure in the elderly.

Takase H, Tanaka T, Takayama S, Nonaka D, Machii M, Sugiura T, Yamashita S, Ohte N, Dohi Y.

Medicine (Baltimore). 2017 Dec;96(50):e9116. doi: 10.1097/MD.0000000000009116.


Intracellular Renin Inhibits Mitochondrial Permeability Transition Pore via Activated Mitochondrial Extracellular Signal-Regulated Kinase (ERK) 1/2 during Ischemia in Diabetic Hearts.

Satoh T, Saotome M, Katoh H, Nonaka D, Hasan P, Hayashi H, Maekawa Y.

Int J Mol Sci. 2017 Dec 25;19(1). pii: E55. doi: 10.3390/ijms19010055.


Evaluation of NGS and RT-PCR Methods for ALK Rearrangement in European NSCLC Patients: Results from the European Thoracic Oncology Platform Lungscape Project.

Letovanec I, Finn S, Zygoura P, Smyth P, Soltermann A, Bubendorf L, Speel EJ, Marchetti A, Nonaka D, Monkhorst K, Hager H, Martorell M, Sejda A, Cheney R, Hernandez-Losa J, Verbeken E, Weder W, Savic S, Di Lorito A, Navarro A, Felip E, Warth A, Baas P, Meldgaard P, Blackhall F, Dingemans AM, Dienemann H, Dziadziuszko R, Vansteenkiste J, O'Brien C, Geiger T, Sherlock J, Schageman J, Dafni U, Kammler R, Kerr K, Thunnissen E, Stahel R, Peters S; European Thoracic Oncology Platform Lungscape Consortium.

J Thorac Oncol. 2018 Mar;13(3):413-425. doi: 10.1016/j.jtho.2017.11.117. Epub 2017 Nov 27.


Individual and household factors associated with incidences of village malaria in Xepon district, Savannakhet province, Lao PDR.

Inthavong N, Nonaka D, Kounnavong S, Iwagami M, Phommala S, Kobayashi J, Hongvanthong B, Pongvongsa T, Brey PT, Kano S.

Trop Med Health. 2017 Nov 7;45:36. doi: 10.1186/s41182-017-0077-2. eCollection 2017.


Higher Expression of Activation-induced Cytidine Deaminase Is Significantly Associated with Merkel Cell Polyomavirus-negative Merkel Cell Carcinomas.

Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Kato M, Kitamura Y, Hayashi K.

Yonago Acta Med. 2017 Sep 15;60(3):145-153. eCollection 2017 Sep.


Prevalence and clinical association of MET gene overexpression and amplification in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape project.

Bubendorf L, Dafni U, Schöbel M, Finn SP, Tischler V, Sejda A, Marchetti A, Thunnissen E, Verbeken EK, Warth A, Sansano I, Cheney R, Speel EJM, Nonaka D, Monkhorst K, Hager H, Martorell M, Savic S, Kerr KM, Tan Q, Tsourti Z, Geiger TR, Kammler R, Schulze K, Das-Gupta A, Shames D, Peters S, Stahel RA; Lungscape Consortium.

Lung Cancer. 2017 Sep;111:143-149. doi: 10.1016/j.lungcan.2017.07.021. Epub 2017 Jul 22.


A study of appendiceal crypt cell adenocarcinoma (so-called goblet cell carcinoid and its related adenocarcinoma).

Nonaka D, Papaxoinis G, Lamarca A, Fulford P, Valle J, Chakrabarty B.

Hum Pathol. 2018 Feb;72:18-27. doi: 10.1016/j.humpath.2017.08.005. Epub 2017 Aug 18.


Purulent Pericarditis with Salmonella enterica Subspecies arizona in a Patient with Type 2 Diabetes Mellitus.

Suzuki A, Tanaka T, Ohba K, Ito N, Sakai Y, Kaneko A, Machii M, Nonaka D, Goto Y, Takase H.

Intern Med. 2017 Aug 15;56(16):2171-2174. doi: 10.2169/internalmedicine.8293-16. Epub 2017 Aug 1.


A Unique Subset of γδ T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria.

Taniguchi T, Md Mannoor K, Nonaka D, Toma H, Li C, Narita M, Vanisaveth V, Kano S, Takahashi M, Watanabe H.

Front Microbiol. 2017 Jul 19;8:1288. doi: 10.3389/fmicb.2017.01288. eCollection 2017.


Quantitative measurement of a candidate serum biomarker peptide derived from α2-HS-glycoprotein, and a preliminary trial of multidimensional peptide analysis in females with pregnancy-induced hypertension.

Hamamura K, Yanagida M, Ishikawa H, Banzai M, Yoshitake H, Nonaka D, Tanaka K, Sakuraba M, Miyakuni Y, Takamori K, Nojima M, Yoshida K, Fujiwara H, Takeda S, Araki Y.

Ann Clin Biochem. 2018 Mar;55(2):287-295. doi: 10.1177/0004563217717748. Epub 2017 Jul 17.


Association of expression of the hedgehog signal with Merkel cell polyomavirus infection and prognosis of Merkel cell carcinoma.

Kuromi T, Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Kato M, Akizuki G, Kitamura Y, Hayashi K.

Hum Pathol. 2017 Nov;69:8-14. doi: 10.1016/j.humpath.2017.05.011. Epub 2017 Jun 28.


A study of FoxA1 expression in thyroid tumors.

Nonaka D.

Hum Pathol. 2017 Jul;65:217-224. doi: 10.1016/j.humpath.2017.05.007. Epub 2017 May 22.


The dark side of T1 non-appendiceal small bowel neuroendocrine tumors.

Salih Z, Lamarca A, Nonaka D, Hubner RA, de Liguori-Carino N, McNamara MG, Fulford P, Minicozzi A, O'Dwyer S, Chakrabarty B, Valle JW.

Hum Pathol. 2017 Aug;66:239-240. doi: 10.1016/j.humpath.2017.02.030. Epub 2017 May 9. No abstract available.


Cysteinylated transthyretin as a discriminator of cardiovascular risk in patients with diabetes mellitus.

Wakabayashi I, Marumo M, Nonaka D, Lee LJ, Mukai J, Ohki M, Tanaka K, Uchida K.

Clin Chim Acta. 2017 Jul;470:46-50. doi: 10.1016/j.cca.2017.04.015. Epub 2017 Apr 20.


68Gallium DOTANOC-PET Imaging in Lung Carcinoids: Impact on Patients' Management.

Lamarca A, Pritchard DM, Westwood T, Papaxoinis G, Nonaka D, Vinjamuri S, Valle JW, Manoharan P, Mansoor W.

Neuroendocrinology. 2018;106(2):128-138. doi: 10.1159/000472717. Epub 2017 Apr 12.


High-grade Neuroendocrine Carcinoma of the Lung With Carcinoid Morphology: A Study of 12 Cases.

Quinn AM, Chaturvedi A, Nonaka D.

Am J Surg Pathol. 2017 Feb;41(2):263-270. doi: 10.1097/PAS.0000000000000767.


Prognostic Significance of CD44 and Orthopedia Homeobox Protein (OTP) Expression in Pulmonary Carcinoid Tumours.

Papaxoinis G, Nonaka D, O'Brien C, Sanderson B, Krysiak P, Mansoor W.

Endocr Pathol. 2017 Mar;28(1):60-70. doi: 10.1007/s12022-016-9459-y.


Evaluation of diagnostic and prognostic significance of Ki-67 index in pulmonary carcinoid tumours.

Clay V, Papaxoinis G, Sanderson B, Valle JW, Howell M, Lamarca A, Krysiak P, Bishop P, Nonaka D, Mansoor W.

Clin Transl Oncol. 2017 May;19(5):579-586. doi: 10.1007/s12094-016-1568-z. Epub 2016 Nov 15.


Vasculogenic mimicry in small cell lung cancer.

Williamson SC, Metcalf RL, Trapani F, Mohan S, Antonello J, Abbott B, Leong HS, Chester CP, Simms N, Polanski R, Nonaka D, Priest L, Fusi A, Carlsson F, Carlsson A, Hendrix MJ, Seftor RE, Seftor EA, Rothwell DG, Hughes A, Hicks J, Miller C, Kuhn P, Brady G, Simpson KL, Blackhall FH, Dive C.

Nat Commun. 2016 Nov 9;7:13322. doi: 10.1038/ncomms13322.


Household clustering of asymptomatic malaria infections in Xepon district, Savannakhet province, Lao PDR.

Pongvongsa T, Nonaka D, Iwagami M, Nakatsu M, Phongmany P, Nishimoto F, Kobayashi J, Hongvanthon B, Brey PT, Moji K, Mita T, Kano S.

Malar J. 2016 Oct 18;15(1):508.


Association of serum 25-hydroxyvitamin D with influenza in case-control study nested in a cohort of Japanese employees.

Nanri A, Nakamoto K, Sakamoto N, Imai T, Akter S, Nonaka D, Mizoue T.

Clin Nutr. 2017 Oct;36(5):1288-1293. doi: 10.1016/j.clnu.2016.08.016. Epub 2016 Aug 26.


School-based intervention to enable school children to act as change agents on weight, physical activity and diet of their mothers: a cluster randomized controlled trial.

Gunawardena N, Kurotani K, Indrawansa S, Nonaka D, Mizoue T, Samarasinghe D.

Int J Behav Nutr Phys Act. 2016 Apr 6;13:45. doi: 10.1186/s12966-016-0369-7.


Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study.

Morrow CJ, Trapani F, Metcalf RL, Bertolini G, Hodgkinson CL, Khandelwal G, Kelly P, Galvin M, Carter L, Simpson KL, Williamson S, Wirth C, Simms N, Frankliln L, Frese KK, Rothwell DG, Nonaka D, Miller CJ, Brady G, Blackhall FH, Dive C.

Ann Oncol. 2016 Jun;27(6):1155-60. doi: 10.1093/annonc/mdw122. Epub 2016 Mar 24.

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