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Items: 1 to 50 of 84

1.

Role for Gag-CA Interdomain Linker in Primate Lentiviral Replication.

Doi N, Koma T, Adachi A, Nomaguchi M.

Front Microbiol. 2019 Aug 7;10:1831. doi: 10.3389/fmicb.2019.01831. eCollection 2019.

2.

Allosteric Regulation of HIV-1 Capsid Structure for Gag Assembly, Virion Production, and Viral Infectivity by a Disordered Interdomain Linker.

Koma T, Kotani O, Miyakawa K, Ryo A, Yokoyama M, Doi N, Adachi A, Sato H, Nomaguchi M.

J Virol. 2019 Aug 13;93(17). pii: e00381-19. doi: 10.1128/JVI.00381-19. Print 2019 Sep 1.

PMID:
31189701
3.

PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.

Miyakawa K, Matsunaga S, Yokoyama M, Nomaguchi M, Kimura Y, Nishi M, Kimura H, Sato H, Hirano H, Tamura T, Akari H, Miura T, Adachi A, Sawasaki T, Yamamoto N, Ryo A.

Nat Commun. 2019 Apr 23;10(1):1844. doi: 10.1038/s41467-019-09867-7.

4.

Concomitant Enhancement of HIV-1 Replication Potential and Neutralization-Resistance in Concert With Three Adaptive Mutations in Env V1/C2/C4 Domains.

Doi N, Yokoyama M, Koma T, Kotani O, Sato H, Adachi A, Nomaguchi M.

Front Microbiol. 2019 Jan 17;10:2. doi: 10.3389/fmicb.2019.00002. eCollection 2019.

5.

CXCR4- and CCR5-Tropic HIV-1 Clones Are Both Tractable to Grow in Rhesus Macaques.

Doi N, Miura T, Mori H, Sakawaki H, Koma T, Adachi A, Nomaguchi M.

Front Microbiol. 2018 Oct 18;9:2510. doi: 10.3389/fmicb.2018.02510. eCollection 2018.

6.

Virological characterization of HIV-1 CA-NTD mutants constructed in a virus-lineage reflected manner.

Nakanishi S, Watanabe S, Doi N, Koma T, Adachi A, Nomaguchi M.

J Med Invest. 2018;65(1.2):110-115. doi: 10.2152/jmi.65.110.

7.

Production of HIV-1 vif mRNA Is Modulated by Natural Nucleotide Variations and SLSA1 RNA Structure in SA1D2prox Genomic Region.

Nomaguchi M, Doi N, Yoshida T, Koma T, Adachi S, Ode H, Iwatani Y, Yokoyama M, Sato H, Adachi A.

Front Microbiol. 2017 Dec 18;8:2542. doi: 10.3389/fmicb.2017.02542. eCollection 2017.

8.

Editorial: Highly Mutable Animal RNA Viruses: Adaptation and Evolution.

Nomaguchi M, Adachi A.

Front Microbiol. 2017 Sep 15;8:1785. doi: 10.3389/fmicb.2017.01785. eCollection 2017. No abstract available.

9.

Complete Genome Sequences of Human Immunodeficiency Type 1 Viruses Genetically Engineered To Be Tropic for Rhesus Macaques.

Nomaguchi M, Doi N, Koma T, Adachi A.

Genome Announc. 2017 Sep 28;5(39). pii: e01063-17. doi: 10.1128/genomeA.01063-17.

10.

Generation and characterization of new CCR5-tropic HIV-1rmt clones.

Doi N, Sakai Y, Adachi A, Nomaguchi M.

J Med Invest. 2017;64(3.4):272-279. doi: 10.2152/jmi.64.272.

11.

HIV-1 mutates to adapt in fluxing environments.

Nomaguchi M, Doi N, Koma T, Adachi A.

Microbes Infect. 2018 Oct - Nov;20(9-10):610-614. doi: 10.1016/j.micinf.2017.08.003. Epub 2017 Aug 30. Review.

PMID:
28859896
12.

Novel In Vitro Screening System Based on Differential Scanning Fluorimetry to Search for Small Molecules against the Disassembly or Assembly of HIV-1 Capsid Protein.

Miyazaki Y, Doi N, Koma T, Adachi A, Nomaguchi M.

Front Microbiol. 2017 Jul 24;8:1413. doi: 10.3389/fmicb.2017.01413. eCollection 2017.

13.

Comparison of Biochemical Properties of HIV-1 and HIV-2 Capsid Proteins.

Miyazaki Y, Miyake A, Doi N, Koma T, Uchiyama T, Adachi A, Nomaguchi M.

Front Microbiol. 2017 Jun 13;8:1082. doi: 10.3389/fmicb.2017.01082. eCollection 2017.

14.

Phylogenetic Insights into the Functional Relationship between Primate Lentiviral Reverse Transcriptase and Accessory Proteins Vpx/Vpr.

Sakai Y, Doi N, Miyazaki Y, Adachi A, Nomaguchi M.

Front Microbiol. 2016 Oct 18;7:1655. eCollection 2016.

15.

Expression Profiles of Vpx/Vpr Proteins Are Co-related with the Primate Lentiviral Lineage.

Sakai Y, Miyake A, Doi N, Sasada H, Miyazaki Y, Adachi A, Nomaguchi M.

Front Microbiol. 2016 Aug 3;7:1211. doi: 10.3389/fmicb.2016.01211. eCollection 2016.

16.

Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels.

Nomaguchi M, Doi N, Sakai Y, Ode H, Iwatani Y, Ueno T, Matsumoto Y, Miyazaki Y, Masuda T, Adachi A.

J Virol. 2016 Apr 14;90(9):4563-4578. doi: 10.1128/JVI.02939-15. Print 2016 May.

17.

In silico Analysis of HIV-1 Env-gp120 Reveals Structural Bases for Viral Adaptation in Growth-Restrictive Cells.

Yokoyama M, Nomaguchi M, Doi N, Kanda T, Adachi A, Sato H.

Front Microbiol. 2016 Feb 9;7:110. doi: 10.3389/fmicb.2016.00110. eCollection 2016.

18.

Novel mutant human immunodeficiency virus type 1 strains with high degree of resistance to cynomolgus macaque TRIMCyp generated by random mutagenesis.

Sultana T, Nakayama EE, Tobita S, Yokoyama M, Seki Y, Saito A, Nomaguchi M, Adachi A, Akari H, Sato H, Shioda T.

J Gen Virol. 2016 Apr;97(4):963-76. doi: 10.1099/jgv.0.000408. Epub 2016 Jan 20.

19.

Single-amino acid mutation 66SR in Gag-matrix enhances viral single-cycle infectivity of R5-tropic HIV-1rmt.

Doi N, Sakai Y, Miyazaki Y, Adachi A, Nomaguchi M.

J Med Invest. 2015;62(3-4):228-32. doi: 10.2152/jmi.62.228.

21.

Distinct combinations of amino acid substitutions in N-terminal domain of Gag-capsid afford HIV-1 resistance to rhesus TRIM5α.

Nomaguchi M, Nakayama EE, Yokoyama M, Doi N, Igarashi T, Shioda T, Sato H, Adachi A.

Microbes Infect. 2014 Nov;16(11):936-44. doi: 10.1016/j.micinf.2014.08.017. Epub 2014 Sep 4.

PMID:
25195168
22.

Virological characterization of HIV-2 vpx gene mutants in various cell systems.

Nomaguchi M, Doi N, Adachi A.

Microbes Infect. 2014 Aug;16(8):695-701. doi: 10.1016/j.micinf.2014.06.004. Epub 2014 Jun 21.

PMID:
24956595
23.

Role of poly-proline motif in HIV-2 Vpx expression.

Miyake A, Miyazaki Y, Fujita M, Nomaguchi M, Adachi A.

Front Microbiol. 2014 Jan 28;5:24. doi: 10.3389/fmicb.2014.00024. eCollection 2014. No abstract available.

24.

Natural single-nucleotide polymorphisms in the 3' region of the HIV-1 pol gene modulate viral replication ability.

Nomaguchi M, Miyake A, Doi N, Fujiwara S, Miyazaki Y, Tsunetsugu-Yokota Y, Yokoyama M, Sato H, Masuda T, Adachi A.

J Virol. 2014 Apr;88(8):4145-60. doi: 10.1128/JVI.01859-13. Epub 2014 Jan 29.

25.

Poly-proline motif in HIV-2 Vpx is critical for its efficient translation.

Miyake A, Fujita M, Fujino H, Koga R, Kawamura S, Otsuka M, Ode H, Iwatani Y, Sakai Y, Doi N, Nomaguchi M, Adachi A, Miyazaki Y.

J Gen Virol. 2014 Jan;95(Pt 1):179-89. doi: 10.1099/vir.0.057364-0. Epub 2013 Oct 10.

PMID:
24114794
26.

Generation of rhesus macaque-tropic HIV-1 clones that are resistant to major anti-HIV-1 restriction factors.

Nomaguchi M, Yokoyama M, Kono K, Nakayama EE, Shioda T, Doi N, Fujiwara S, Saito A, Akari H, Miyakawa K, Ryo A, Ode H, Iwatani Y, Miura T, Igarashi T, Sato H, Adachi A.

J Virol. 2013 Nov;87(21):11447-61. doi: 10.1128/JVI.01549-13. Epub 2013 Aug 21.

27.

Growth potentials of CCR5-tropic/CXCR4-tropic HIV-1mt clones in macaque cells.

Doi N, Okubo A, Yamane M, Sakai Y, Adachi A, Nomaguchi M.

Front Microbiol. 2013 Jul 29;4:218. doi: 10.3389/fmicb.2013.00218. eCollection 2013. No abstract available.

28.

TRIM5 genotypes in cynomolgus monkeys primarily influence inter-individual diversity in susceptibility to monkey-tropic human immunodeficiency virus type 1.

Saito A, Nomaguchi M, Kono K, Iwatani Y, Yokoyama M, Yasutomi Y, Sato H, Shioda T, Sugiura W, Matano T, Adachi A, Nakayama EE, Akari H.

J Gen Virol. 2013 Jun;94(Pt 6):1318-24. doi: 10.1099/vir.0.050252-0. Epub 2013 Mar 13.

PMID:
23486671
29.

Systemic biological analysis of the mutations in two distinct HIV-1mt genomes occurred during replication in macaque cells.

Nomaguchi M, Doi N, Fujiwara S, Saito A, Akari H, Nakayama EE, Shioda T, Yokoyama M, Sato H, Adachi A.

Microbes Infect. 2013 Apr;15(4):319-28. doi: 10.1016/j.micinf.2013.01.005. Epub 2013 Feb 4.

PMID:
23384722
30.

Gag-CA Q110D mutation elicits TRIM5-independent enhancement of HIV-1mt replication in macaque cells.

Nomaguchi M, Yokoyama M, Kono K, Nakayama EE, Shioda T, Saito A, Akari H, Yasutomi Y, Matano T, Sato H, Adachi A.

Microbes Infect. 2013 Jan;15(1):56-65. doi: 10.1016/j.micinf.2012.10.013. Epub 2012 Nov 1.

PMID:
23123544
31.

Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu.

Miyakawa K, Sawasaki T, Matsunaga S, Tokarev A, Quinn G, Kimura H, Nomaguchi M, Adachi A, Yamamoto N, Guatelli J, Ryo A.

Sci Signal. 2012 Oct 9;5(245):ra73. doi: 10.1126/scisignal.2003212.

32.

SAMHD1-Dependent and -Independent Functions of HIV-2/SIV Vpx Protein.

Fujita M, Nomaguchi M, Adachi A, Otsuka M.

Front Microbiol. 2012 Aug 10;3:297. doi: 10.3389/fmicb.2012.00297. eCollection 2012.

33.

Viral tropism.

Nomaguchi M, Fujita M, Miyazaki Y, Adachi A.

Front Microbiol. 2012 Aug 3;3:281. doi: 10.3389/fmicb.2012.00281. eCollection 2012. No abstract available.

34.

Species tropism of HIV-1 modulated by viral accessory proteins.

Nomaguchi M, Doi N, Matsumoto Y, Sakai Y, Fujiwara S, Adachi A.

Front Microbiol. 2012 Jul 26;3:267. doi: 10.3389/fmicb.2012.00267. eCollection 2012.

35.

Structural biology for virus research.

Miyazaki Y, Fujita M, Nomaguchi M, Adachi A.

Front Microbiol. 2012 Mar 13;3:91. doi: 10.3389/fmicb.2012.00091. eCollection 2012. No abstract available.

36.

Structural dynamics of retroviral genome and the packaging.

Miyazaki Y, Miyake A, Nomaguchi M, Adachi A.

Front Microbiol. 2011 Dec 29;2:264. doi: 10.3389/fmicb.2011.00264. eCollection 2011.

37.

Geographical, genetic and functional diversity of antiretroviral host factor TRIMCyp in cynomolgus macaque (Macaca fascicularis).

Saito A, Kono K, Nomaguchi M, Yasutomi Y, Adachi A, Shioda T, Akari H, Nakayama EE.

J Gen Virol. 2012 Mar;93(Pt 3):594-602. doi: 10.1099/vir.0.038075-0. Epub 2011 Nov 23.

38.

Commentary on a New Era of Investigating 3D Structure-Based Human-Virus Protein Network Dynamics.

Adachi S, Adachi A, Nomaguchi M.

Front Microbiol. 2011 Sep 8;2:186. doi: 10.3389/fmicb.2011.00186. eCollection 2011. No abstract available.

39.

Rhesus M1.3S Cells Suitable for Biological Evaluation of Macaque-Tropic HIV/SIV Clones.

Doi N, Fujiwara S, Adachi A, Nomaguchi M.

Front Microbiol. 2011 May 23;2:115. doi: 10.3389/fmicb.2011.00115. eCollection 2011. No abstract available.

40.

The Fourth Major Restriction Factor Against HIV/SIV.

Nomaguchi M, Fujita M, Adachi A.

Front Microbiol. 2011 Jun 10;2:132. doi: 10.3389/fmicb.2011.00132. eCollection 2011. No abstract available.

41.

HIV-1 Vpr and G2 cell cycle arrest.

Nomaguchi M, Adachi A.

Future Microbiol. 2011 Apr;6(4):375-8. doi: 10.2217/fmb.11.17.

PMID:
21526938
42.

[HIV infection].

Nomaguchi M, Adachi A.

Nihon Rinsho. 2010 Aug;68 Suppl 8:518-22. Review. Japanese. No abstract available.

PMID:
20976926
43.

Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications.

Saito A, Nomaguchi M, Iijima S, Kuroishi A, Yoshida T, Lee YJ, Hayakawa T, Kono K, Nakayama EE, Shioda T, Yasutomi Y, Adachi A, Matano T, Akari H.

Microbes Infect. 2011 Jan;13(1):58-64. doi: 10.1016/j.micinf.2010.10.001. Epub 2010 Oct 16.

PMID:
20955815
44.

Growth ability in various macaque cell lines of HIV-1 with simian cell-tropism.

Doi N, Fujiwara S, Adachi A, Nomaguchi M.

J Med Invest. 2010 Aug;57(3-4):284-92.

45.

Different interaction between HIV-1 Vif and its cellular target proteins APOBEC3G/APOBEC3F.

Nagao T, Yamashita T, Miyake A, Uchiyama T, Nomaguchi M, Adachi A.

J Med Invest. 2010 Feb;57(1-2):89-94.

46.

Multifaceted activity of HIV Vpr/Vpx proteins: the current view of their virological functions.

Fujita M, Otsuka M, Nomaguchi M, Adachi A.

Rev Med Virol. 2010 Mar;20(2):68-76. doi: 10.1002/rmv.636. Review.

PMID:
20069611
47.

Virology as biosystematics: towards understanding the viral infection biology.

Nomaguchi M, Adachi A.

Front Microbiol. 2010 Jul 20;1:2. doi: 10.3389/fmicb.2010.00002. eCollection 2010. No abstract available.

48.

Site-Directed Mutagenesis of HIV-1 vpu Gene Demonstrates Two Clusters of Replication-Defective Mutants with Distinct Ability to Down-Modulate Cell Surface CD4 and Tetherin.

Nomaguchi M, Doi N, Fujiwara S, Fujita M, Adachi A.

Front Microbiol. 2010 Nov 24;1:116. doi: 10.3389/fmicb.2010.00116. eCollection 2010.

49.

Status of APOBEC3G/F in cells and progeny virions modulated by Vif determines HIV-1 infectivity.

Yamashita T, Nomaguchi M, Miyake A, Uchiyama T, Adachi A.

Microbes Infect. 2010 Feb;12(2):166-71. doi: 10.1016/j.micinf.2009.11.007. Epub 2009 Nov 26.

PMID:
19944180
50.

[Accessory proteins of HIV and innate anti-retroviral factors].

Nomaguchi M, Adachi A.

Uirusu. 2009 Jun;59(1):67-74. Review. Japanese.

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