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Items: 1 to 50 of 92

1.

Bile acid changes after metabolic surgery are linked to improvement in insulin sensitivity.

Ahlin S, Cefalù C, Bondia-Pons I, Capristo E, Marini L, Gastaldelli A, Mingrone G, Nolan JJ.

Br J Surg. 2019 Aug;106(9):1178-1186. doi: 10.1002/bjs.11208. Epub 2019 Jun 19.

PMID:
31216062
2.

Phenotypic Responses to a Lifestyle Intervention Do Not Account for Inter-Individual Variability in Glucose Tolerance for Individuals at High Risk of Type 2 Diabetes.

O'Donoghue G, Kennedy A, Andersen GS, Carr B, Cleary S, Durkan E, Davis H, Færch K, Fitzpatrick P, Kenny H, McCaffrey N, Monedero J, Murphy E, Noone J, Suvitaival T, Thybo T, Wheeler M, Vistisen D, Nolan JJ, O'Gorman DJ.

Front Physiol. 2019 Mar 26;10:317. doi: 10.3389/fphys.2019.00317. eCollection 2019.

3.

Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation.

Shah UJ, Xie W, Flyvbjerg A, Nolan JJ, Højlund K, Walker M, Relton CL, Elliott HR; RISC consortium.

Diabetes Res Clin Pract. 2019 Feb;148:189-199. doi: 10.1016/j.diabres.2019.01.008. Epub 2019 Jan 11.

4.

Study protocol for the Cities Changing Diabetes programme: a global mixed-methods approach.

Napier AD, Nolan JJ, Bagger M, Hesseldal L, Volkmann AM.

BMJ Open. 2017 Nov 8;7(11):e015240. doi: 10.1136/bmjopen-2016-015240.

5.

Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism.

Hernández-Alvarez MI, Díaz-Ramos A, Berdasco M, Cobb J, Planet E, Cooper D, Pazderska A, Wanic K, O'Hanlon D, Gomez A, de la Ballina LR, Esteller M, Palacin M, O'Gorman DJ, Nolan JJ, Zorzano A.

Sci Rep. 2017 Oct 23;7(1):13850. doi: 10.1038/s41598-017-14120-6.

6.

Lipidome as a predictive tool in progression to type 2 diabetes in Finnish men.

Suvitaival T, Bondia-Pons I, Yetukuri L, Pöhö P, Nolan JJ, Hyötyläinen T, Kuusisto J, Orešič M.

Metabolism. 2018 Jan;78:1-12. doi: 10.1016/j.metabol.2017.08.014. Epub 2017 Sep 20.

7.

Incidence of Ketoacidosis in the Danish Type 2 Diabetes Population Before and After Introduction of Sodium-Glucose Cotransporter 2 Inhibitors-A Nationwide, Retrospective Cohort Study, 1995-2014.

Jensen ML, Persson F, Andersen GS, Ridderstråle M, Nolan JJ, Carstensen B, Jørgensen ME.

Diabetes Care. 2017 May;40(5):e57-e58. doi: 10.2337/dc16-2793. Epub 2017 Mar 10. No abstract available.

PMID:
28283564
8.

Is there evidence of potential overtreatment of glycaemia in elderly people with type 2 diabetes? Data from the GUIDANCE study.

Müller N, Khunti K, Kuss O, Lindblad U, Nolan JJ, Rutten GE, Trento M, Porta M, Roth J, Charpentier G, Jörgens V, Müller UA.

Acta Diabetol. 2017 Feb;54(2):209-214. doi: 10.1007/s00592-016-0939-9. Epub 2016 Nov 11.

PMID:
27837286
9.

Testosterone causes both prosocial and antisocial status-enhancing behaviors in human males.

Dreher JC, Dunne S, Pazderska A, Frodl T, Nolan JJ, O'Doherty JP.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11633-11638. Epub 2016 Sep 26.

10.

Beta-cell function is associated with carotid intima-media thickness independently of insulin resistance in healthy individuals.

Roussel R, Natali A, Balkau B, Højlund K, Sánchez G, Nolan JJ, Mari A, Kozakova M, Bonnet F.

J Hypertens. 2016 Apr;34(4):685-91. doi: 10.1097/HJH.0000000000000842.

PMID:
26828784
11.

An evaluation of the DEXLIFE 'self-selected' lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial.

O'Donoghue GM, Kennedy A, Andersen GS, Durkan E, Thybo T, Sinnott M, Nolan JJ, O'Gorman DJ.

Trials. 2015 Nov 18;16:529. doi: 10.1186/s13063-015-1042-1.

12.

Fasting plasma glucose as initial screening for diabetes and prediabetes in irish adults: The Diabetes Mellitus and Vascular health initiative (DMVhi).

Sinnott M, Kinsley BT, Jackson AD, Walsh C, O'Grady T, Nolan JJ, Gaffney P, Boran G, Kelleher C, Carr B.

PLoS One. 2015 Apr 15;10(4):e0122704. doi: 10.1371/journal.pone.0122704. eCollection 2015.

13.

Response to Comment on Pilz et al. Insulin sensitivity and albuminuria: the RISC study. Diabetes Care 2014;37:1597-1603.

Pilz S, Rutters F, Nijpels G, Stehouwer CD, Højlund K, Nolan JJ, Balkau B, Dekker JM; RISC Investigators.

Diabetes Care. 2015 Feb;38(2):e31. doi: 10.2337/dc14-2671. No abstract available.

PMID:
25614703
14.

The DEXLIFE study methods: identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals.

Andersen GS, Thybo T, Cederberg H, Orešič M, Esteller M, Zorzano A, Carr B, Walker M, Cobb J, Clissmann C, O'Gorman DJ, Nolan JJ; DEXLIFE Consortium.

Diabetes Res Clin Pract. 2014 Nov;106(2):383-9. doi: 10.1016/j.diabres.2014.07.025. Epub 2014 Jul 27.

PMID:
25125339
15.

Insulin sensitivity and albuminuria: the RISC study.

Pilz S, Rutters F, Nijpels G, Stehouwer CD, Højlund K, Nolan JJ, Balkau B, Dekker JM; RISC Investigators.

Diabetes Care. 2014 Jun;37(6):1597-603. doi: 10.2337/dc13-2573. Epub 2014 Mar 12.

PMID:
24623021
16.

Impact of glucose tolerance status, sex, and body size on glucose absorption patterns during OGTTs.

Færch K, Pacini G, Nolan JJ, Hansen T, Tura A, Vistisen D.

Diabetes Care. 2013 Nov;36(11):3691-7. doi: 10.2337/dc13-0592. Epub 2013 Sep 23.

17.

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.

Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, el Bouazzaoui F, Collins FS, Dunn SH, Dupuis J, Forouhi NG, Gillson C, Hattersley AT, Hong J, Kähönen M, Kuusisto J, Kedenko L, Kronenberg F, Doria A, Assimes TL, Ferrannini E, Hansen T, Hao K, Häring H, Knowles JW, Lindgren CM, Nolan JJ, Paananen J, Pedersen O, Quertermous T, Smith U; GENESIS Consortium; RISC Consortium, Lehtimäki T, Liu CT, Loos RJ, McCarthy MI, Morris AD, Vasan RS, Spector TD, Teslovich TM, Tuomilehto J, van Dijk KW, Viikari JS, Zhu N, Langenberg C, Ingelsson E, Semple RK, Sinaiko AR, Palmer CN, Walker M, Lam KS, Paulweber B, Mohlke KL, van Duijn C, Raitakari OT, Bidulescu A, Wareham NJ, Laakso M, Waterworth DM, Lawlor DA, Meigs JB, Richards JB, Frayling TM.

Diabetes. 2013 Oct;62(10):3589-98. doi: 10.2337/db13-0128. Epub 2013 Jul 8. Review.

18.

Prevalence and predictors of diabetes and cardiometabolic risk among construction workers in Ireland: the Construction Workers Health Trust screening study.

Thabit H, Burns N, Shah S, Brema I, Crowley V, Finnegan F, Daly B, Nolan JJ.

Diab Vasc Dis Res. 2013 Jul;10(4):337-45. doi: 10.1177/1479164113479808. Epub 2013 Apr 26.

PMID:
23624762
19.

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.

Xie W, Wood AR, Lyssenko V, Weedon MN, Knowles JW, Alkayyali S, Assimes TL, Quertermous T, Abbasi F, Paananen J, Häring H, Hansen T, Pedersen O, Smith U, Laakso M; MAGIC Investigators; DIAGRAM Consortium; GENESIS Consortium; RISC Consortium, Dekker JM, Nolan JJ, Groop L, Ferrannini E, Adam KP, Gall WE, Frayling TM, Walker M.

Diabetes. 2013 Jun;62(6):2141-50. doi: 10.2337/db12-0876. Epub 2013 Feb 1.

20.

Depressive symptoms, insulin sensitivity and insulin secretion in the RISC cohort study.

Bot M, Pouwer F, De Jonge P, Nolan JJ, Mari A, Højlund K, Golay A, Balkau B, Dekker JM.

Diabetes Metab. 2013 Feb;39(1):42-9. doi: 10.1016/j.diabet.2012.09.005. Epub 2012 Nov 20.

PMID:
23182035
21.

Estimating insulin sensitivity and beta cell function: perspectives from the modern pandemics of obesity and type 2 diabetes.

Nolan JJ, Færch K.

Diabetologia. 2012 Nov;55(11):2863-7. doi: 10.1007/s00125-012-2684-0. Epub 2012 Aug 22.

PMID:
22911384
22.

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.

Kilpeläinen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hyppönen E, Cauchi S, He M, Kutalik Z, Kumari M, Stančáková A, Meidtner K, Balkau B, Tan JT, Mangino M, Timpson NJ, Song Y, Zillikens MC, Jablonski KA, Garcia ME, Johansson S, Bragg-Gresham JL, Wu Y, van Vliet-Ostaptchouk JV, Onland-Moret NC, Zimmermann E, Rivera NV, Tanaka T, Stringham HM, Silbernagel G, Kanoni S, Feitosa MF, Snitker S, Ruiz JR, Metter J, Larrad MT, Atalay M, Hakanen M, Amin N, Cavalcanti-Proença C, Grøntved A, Hallmans G, Jansson JO, Kuusisto J, Kähönen M, Lutsey PL, Nolan JJ, Palla L, Pedersen O, Pérusse L, Renström F, Scott RA, Shungin D, Sovio U, Tammelin TH, Rönnemaa T, Lakka TA, Uusitupa M, Rios MS, Ferrucci L, Bouchard C, Meirhaeghe A, Fu M, Walker M, Borecki IB, Dedoussis GV, Fritsche A, Ohlsson C, Boehnke M, Bandinelli S, van Duijn CM, Ebrahim S, Lawlor DA, Gudnason V, Harris TB, Sørensen TI, Mohlke KL, Hofman A, Uitterlinden AG, Tuomilehto J, Lehtimäki T, Raitakari O, Isomaa B, Njølstad PR, Florez JC, Liu S, Ness A, Spector TD, Tai ES, Froguel P, Boeing H, Laakso M, Marmot M, Bergmann S, Power C, Khaw KT, Chasman D, Ridker P, Hansen T, Monda KL, Illig T, Järvelin MR, Wareham NJ, Hu FB, Groop LC, Orho-Melander M, Ekelund U, Franks PW, Loos RJ.

PLoS Med. 2011 Nov;8(11):e1001116. doi: 10.1371/journal.pmed.1001116. Epub 2011 Nov 1.

23.

Gender-specific differences in carotid intima-media thickness and its progression over three years: a multicenter European study.

Kozàkovà M, Palombo C, Morizzo C, Nolan JJ, Konrad T, Dekker JM, Balkau B, Nilsson PM.

Nutr Metab Cardiovasc Dis. 2013 Feb;23(2):151-8. doi: 10.1016/j.numecd.2011.04.006. Epub 2011 Sep 8.

PMID:
21906922
24.

Genetic defects in human pericentrin are associated with severe insulin resistance and diabetes.

Huang-Doran I, Bicknell LS, Finucane FM, Rocha N, Porter KM, Tung YC, Szekeres F, Krook A, Nolan JJ, O'Driscoll M, Bober M, O'Rahilly S, Jackson AP, Semple RK; Majewski Osteodysplastic Primordial Dwarfism Study Group.

Diabetes. 2011 Mar;60(3):925-35. doi: 10.2337/db10-1334. Epub 2011 Jan 26.

25.

Ageing brain abnormalities in young obese patients with type 2 diabetes: a cause for concern.

Nolan JJ.

Diabetologia. 2010 Nov;53(11):2273-5. doi: 10.1007/s00125-010-1890-x. Epub 2010 Aug 30. No abstract available.

PMID:
20803339
26.

Glucose metabolism after normalization of markers of iron overload by venesection in subjects with hereditary hemochromatosis.

Hatunic M, Finucane FM, Norris S, Pacini G, Nolan JJ.

Metabolism. 2010 Dec;59(12):1811-5. doi: 10.1016/j.metabol.2010.06.005. Epub 2010 Aug 1.

PMID:
20673928
27.

Skeletal muscle mitochondrial dysfunction in Type 2 diabetes.

Pazderska A, Wanic K, Nolan JJ.

Expert Rev Endocrinol Metab. 2010 Jul;5(4):475-477. doi: 10.1586/eem.10.21. No abstract available.

PMID:
30780805
28.

Consensus guidelines, algorithms and care of the individual patient with type 2 diabetes.

Nolan JJ.

Diabetologia. 2010 Jul;53(7):1247-9. doi: 10.1007/s00125-010-1767-z. Epub 2010 Apr 25. No abstract available. Erratum in: Diabetologia. 2010 Sep;53(9):2078.

PMID:
20419286
29.

Effect of sedentary behaviour and vigorous physical activity on segment-specific carotid wall thickness and its progression in a healthy population.

Kozàkovà M, Palombo C, Morizzo C, Nolan JJ, Konrad T, Balkau B; RISC Investigators.

Eur Heart J. 2010 Jun;31(12):1511-9. doi: 10.1093/eurheartj/ehq092. Epub 2010 Apr 17.

PMID:
20400760
30.

Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity.

Hernández-Alvarez MI, Thabit H, Burns N, Shah S, Brema I, Hatunic M, Finucane F, Liesa M, Chiellini C, Naon D, Zorzano A, Nolan JJ.

Diabetes Care. 2010 Mar;33(3):645-51. doi: 10.2337/dc09-1305. Epub 2009 Dec 23.

31.

Effect of iron overload on glucose metabolism in patients with hereditary hemochromatosis.

Hatunic M, Finucane FM, Brennan AM, Norris S, Pacini G, Nolan JJ.

Metabolism. 2010 Mar;59(3):380-4. doi: 10.1016/j.metabol.2009.08.006. Epub 2009 Oct 7.

PMID:
19815242
32.

Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals.

Finucane FM, Luan J, Wareham NJ, Sharp SJ, O'Rahilly S, Balkau B, Flyvbjerg A, Walker M, Højlund K, Nolan JJ; (on behalf of the European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular Disease Risk Study Group), Savage DB.

Diabetologia. 2009 Nov;52(11):2345-2349. doi: 10.1007/s00125-009-1508-3. Epub 2009 Sep 12.

33.

Globalization, immigration and diabetes self-management: an empirical study amongst immigrants with type 2 diabetes mellitus in Ireland.

Thabit H, Shah S, Nash M, Brema I, Nolan JJ, Martin G.

QJM. 2009 Oct;102(10):713-20. doi: 10.1093/qjmed/hcp113. Epub 2009 Sep 7.

PMID:
19736289
34.

Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile.

de Rooij SR, Nijpels G, Nilsson PM, Nolan JJ, Gabriel R, Bobbioni-Harsch E, Mingrone G, Dekker JM; Relationship Between Insulin Sensitivity and Cardiovascular Disease (RISC) Investigators.

Diabetes Care. 2009 Jul;32(7):1295-301. doi: 10.2337/dc08-1795. Epub 2009 Apr 14.

35.

The Leu262Val polymorphism of presenilin associated rhomboid like protein (PARL) is associated with earlier onset of type 2 diabetes and increased urinary microalbumin creatinine ratio in an Irish case-control population.

Hatunic M, Stapleton M, Hand E, DeLong C, Crowley VE, Nolan JJ.

Diabetes Res Clin Pract. 2009 Mar;83(3):316-9. doi: 10.1016/j.diabres.2008.12.004. Epub 2009 Jan 29.

PMID:
19185381
36.

Elevated blood pressure in overweight and obese Irish children.

Finucane FM, Pittock S, Fallon M, Hatunic M, Ong K, Burns N, Costigan C, Murphy N, Nolan JJ.

Ir J Med Sci. 2008 Dec;177(4):379-81. doi: 10.1007/s11845-008-0228-x. Epub 2008 Sep 30.

PMID:
18825476
37.

Immigrant patients with type 2 diabetes mellitus have poorer initial and on-going glycemic control than a matched population of Irish patients.

Thabit H, Martin G, Brema I, Daly M, Walsh S, Mannion C, Nolan JJ.

Ir Med J. 2008 Jun;101(6):177-80.

PMID:
18700512
38.

Plasma visfatin is reduced after aerobic exercise in early onset type 2 diabetes mellitus.

Brema I, Hatunic M, Finucane F, Burns N, Nolan JJ, Haider D, Wolzt M, Ludvik B.

Diabetes Obes Metab. 2008 Jul;10(7):600-2. doi: 10.1111/j.1463-1326.2008.00872.x. Epub 2008 May 12. No abstract available.

PMID:
18476987
39.

Effect of diet and physical exercise treatment on insulin resistance syndrome of schoolchildren.

Szamosi A, Czinner A, Szamosi T, Sallai A, Hatunic M, Berla Z, Tomsits E, Almássy Z, Nolan JJ.

J Am Coll Nutr. 2008 Feb;27(1):177-83.

PMID:
18460496
40.

In vivo and in vitro studies of GAD-antibody positive subjects with Type 2 diabetes: A distinct sub-phenotype.

O'Gorman DJ, Yousif O, Dixon G, McQuaid S, Murphy E, Rahman Y, Gasparro D, Pacini G, Newsholme P, Nolan JJ.

Diabetes Res Clin Pract. 2008 Jun;80(3):365-70. doi: 10.1016/j.diabres.2007.12.009. Epub 2008 Apr 10.

PMID:
18405999
41.

Adverse metabolic profiles in a cohort of obese Irish children.

Finucane FM, Teong L, Pittock S, Fallon M, Hatunic M, Costigan C, Murphy N, Crowley VE, Nolan JJ.

Ann Clin Biochem. 2008 Mar;45(Pt 2):206-9. doi: 10.1258/acb.2007.007115.

PMID:
18325187
42.

Free fatty acids in the physiological range are protein-sparing.

Nolan JJ.

Acta Physiol (Oxf). 2008 Mar;192(3):337. doi: 10.1111/j.1748-1716.2007.01801_2.x. No abstract available.

PMID:
18271794
43.

Vascular inflammatory markers in early-onset obese and type 2 diabetes subjects before and after three months' aerobic exercise training.

Hatunic M, Finucane F, Burns N, Gasparro D, Nolan JJ.

Diab Vasc Dis Res. 2007 Sep;4(3):231-4.

PMID:
17907114
44.

Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training.

Burns N, Finucane FM, Hatunic M, Gilman M, Murphy M, Gasparro D, Mari A, Gastaldelli A, Nolan JJ.

Diabetologia. 2007 Jul;50(7):1500-8. Epub 2007 Mar 29.

PMID:
17393133
45.

The cost of treating type 2 diabetes (CODEIRE).

Nolan JJ, O'Halloran D, McKenna TJ, Firth R, Redmond S.

Ir Med J. 2006 Nov-Dec;99(10):307-10.

PMID:
17274175
46.

Attendance at an Irish diabetes dietetic outpatient clinic.

Finucane FM, Gaffney L, Hatunic M, Burns N, Nolan JJ.

Diabetes Res Clin Pract. 2007 Aug;77(2):335-6. Epub 2006 Dec 1. No abstract available.

PMID:
17141352
47.

Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes.

O'Gorman DJ, Karlsson HK, McQuaid S, Yousif O, Rahman Y, Gasparro D, Glund S, Chibalin AV, Zierath JR, Nolan JJ.

Diabetologia. 2006 Dec;49(12):2983-92. Epub 2006 Sep 26.

PMID:
17019595
48.
49.

Contrasting clinical and cardiovascular risk status between early and later onset type 2 diabetes.

Hatunic M, Burns N, Finucane F, Mannion C, Nolan JJ.

Diab Vasc Dis Res. 2005 May;2(2):73-5.

PMID:
16305062
50.

Emergency management of hypoglycaemia: quantitative considerations.

Nolan JJ.

Eur J Emerg Med. 2005 Oct;12(5):213-5. No abstract available.

PMID:
16175056

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