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Items: 1 to 50 of 402

1.

Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells.

Teh CE, Gong JN, Segal D, Tan T, Vandenberg CJ, Fedele PL, Low MSY, Grigoriadis G, Harrison SJ, Strasser A, Roberts AW, Huang DCS, Nolan GP, Gray DHD, Ko ME.

Cell Death Differ. 2020 Jan 27. doi: 10.1038/s41418-020-0498-z. [Epub ahead of print]

PMID:
31988495
2.

Enabling Technologies for Personalized and Precision Medicine.

Ho D, Quake SR, McCabe ERB, Chng WJ, Chow EK, Ding X, Gelb BD, Ginsburg GS, Hassenstab J, Ho CM, Mobley WC, Nolan GP, Rosen ST, Tan P, Yen Y, Zarrinpar A.

Trends Biotechnol. 2020 Jan 21. pii: S0167-7799(19)30316-6. doi: 10.1016/j.tibtech.2019.12.021. [Epub ahead of print] Review.

PMID:
31980301
3.

FLOW-MAP: a graph-based, force-directed layout algorithm for trajectory mapping in single-cell time course datasets.

Ko ME, Williams CM, Fread KI, Goggin SM, Rustagi RS, Fragiadakis GK, Nolan GP, Zunder ER.

Nat Protoc. 2020 Feb;15(2):398-420. doi: 10.1038/s41596-019-0246-3. Epub 2020 Jan 13.

PMID:
31932774
4.

Profiling myelodysplastic syndromes by mass cytometry demonstrates abnormal progenitor cell phenotype and differentiation.

Behbehani GK, Finck R, Samusik N, Sridhar K, Fantl WJ, Greenberg PL, Nolan GP.

Cytometry B Clin Cytom. 2020 Jan 9. doi: 10.1002/cyto.b.21860. [Epub ahead of print]

PMID:
31917512
5.

Sex Differences in the Blood Transcriptome Identify Robust Changes in Immune Cell Proportions with Aging and Influenza Infection.

Bongen E, Lucian H, Khatri A, Fragiadakis GK, Bjornson ZB, Nolan GP, Utz PJ, Khatri P.

Cell Rep. 2019 Nov 12;29(7):1961-1973.e4. doi: 10.1016/j.celrep.2019.10.019.

6.

TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis.

Baskar R, Fienberg HG, Khair Z, Favaro P, Kimmey S, Green DR, Nolan GP, Plevritis S, Bendall SC.

Life Sci Alliance. 2019 Nov 8;2(6). pii: e201900554. doi: 10.26508/lsa.201900554. Print 2019 Dec.

7.

Delay to Adjuvant Chemotherapy: Survival and Recurrence in Patients of Rectal Cancer Treated with Neo-adjuvant Chemoradiotherapy and Surgery.

Thong DW, Kim J, Naik A, Lu CT, Nolan GJ, Von Papen M.

J Gastrointest Cancer. 2019 Nov 5. doi: 10.1007/s12029-019-00312-y. [Epub ahead of print]

PMID:
31691086
8.

Firework-related blast injury to the hand and treatment algorithm.

Mohan A, Nolan GS, Jain A.

BMJ Case Rep. 2019 Oct 23;12(10). pii: e231804. doi: 10.1136/bcr-2019-231804.

PMID:
31645382
9.

MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure.

Keren L, Bosse M, Thompson S, Risom T, Vijayaragavan K, McCaffrey E, Marquez D, Angoshtari R, Greenwald NF, Fienberg H, Wang J, Kambham N, Kirkwood D, Nolan G, Montine TJ, Galli SJ, West R, Bendall SC, Angelo M.

Sci Adv. 2019 Oct 9;5(10):eaax5851. doi: 10.1126/sciadv.aax5851. eCollection 2019 Oct.

10.

Voices in methods development.

Anikeeva P, Boyden E, Brangwynne C, Cissé II, Fiehn O, Fromme P, Gingras AC, Greene CS, Heard E, Hell SW, Hillman E, Jensen GJ, Karchin R, Kiessling LL, Kleinstiver BP, Knight R, Kukura P, Lancaster MA, Loman N, Looger L, Lundberg E, Luo Q, Miyawaki A, Myers EW Jr, Nolan GP, Picotti P, Reik W, Sauer M, Shalek AK, Shendure J, Slavov N, Tanay A, Troyanskaya O, van Valen D, Wang HW, Yi C, Yin P, Zernicka-Goetz M, Zhuang X.

Nat Methods. 2019 Oct;16(10):945-951. doi: 10.1038/s41592-019-0585-6. No abstract available.

PMID:
31562479
11.

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.

Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, Zahra D, Chaudhri G, Karupiah G, Whittle B, Roots C, Bertram E, Yamada M, Jeelall Y, Enders A, Clifton BE, Mabbitt PD, Jackson CJ, Watson SR, Jenne CN, Lanier LL, Wiltshire T, Spitzer MH, Nolan GP, Schmitz F, Aderem A, Porebski BT, Buckle AM, Abbott DW, Ziegler JB, Craig ME, Benitez-Aguirre P, Teo J, Tangye SG, King C, Wong M, Cox MP, Phung W, Tang J, Sandoval W, Wertz IE, Christ D, Goodnow CC, Grey ST.

Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18.

PMID:
31534238
12.

Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation.

Ding X, Krutzik PO, Ghaffari AA, Zhaozhi Y, Miranda D Jr, Cheng G, Ho CM, Nolan GP, Sanchez DJ.

Antiviral Res. 2019 Nov;171:104598. doi: 10.1016/j.antiviral.2019.104598. Epub 2019 Sep 9.

PMID:
31513822
13.

A Comparative Study of Auditory-Perceptual Speech Measures for the Early Detection of Mild Speech Impairments.

Kuruvilla-Dugdale M, Threlkeld K, Salazar M, Nolan G, Heidrick L.

Semin Speech Lang. 2019 Nov;40(5):394-406. doi: 10.1055/s-0039-1694997. Epub 2019 Aug 19.

14.

Role for polo-like kinase 4 in mediation of cytokinesis.

Press MF, Xie B, Davenport S, Zhou Y, Guzman R, Nolan GP, O'Brien N, Palazzolo M, Mak TW, Brugge JS, Slamon DJ.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11309-11318. doi: 10.1073/pnas.1818820116. Epub 2019 May 16.

15.

Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis.

Hartmann FJ, Simonds EF, Vivanco N, Bruce T, Borges L, Nolan GP, Spitzer MH, Bendall SC.

Methods Mol Biol. 2019;1989:55-81. doi: 10.1007/978-1-4939-9454-0_5.

16.

A 13-year review of plastic and hand surgery research funding by the National Institute of Health Research.

Nolan GS, Jain A.

J Plast Reconstr Aesthet Surg. 2019 Jun;72(6):1030-1048. doi: 10.1016/j.bjps.2019.02.003. Epub 2019 Mar 2. No abstract available.

PMID:
30853314
17.

Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells.

Good Z, Borges L, Vivanco Gonzalez N, Sahaf B, Samusik N, Tibshirani R, Nolan GP, Bendall SC.

Nat Biotechnol. 2019 Mar;37(3):259-266. doi: 10.1038/s41587-019-0033-2. Epub 2019 Feb 11.

18.

Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry.

Duckworth AD, Gherardini PF, Sykorova M, Yasin F, Nolan GP, Slupsky JR, Kalakonda N.

Nat Protoc. 2019 Mar;14(3):901-920. doi: 10.1038/s41596-018-0120-8. Epub 2019 Feb 6.

PMID:
30728478
19.

Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control.

Pohlmeyer CW, Gonzalez VD, Irrinki A, Ramirez RN, Li L, Mulato A, Murry JP, Arvey A, Hoh R, Deeks SG, Kukolj G, Cihlar T, Pflanz S, Nolan GP, Min-Oo G.

J Virol. 2019 Mar 21;93(7). pii: e01790-18. doi: 10.1128/JVI.01790-18. Print 2019 Apr 1.

20.

Enhancing Engagement With Socially Disadvantaged Older People in Organized Physical Activity Programs.

Nau T, Nolan G, Smith BJ.

Int Q Community Health Educ. 2019 Jul;39(4):257-267. doi: 10.1177/0272684X18821301. Epub 2019 Jan 14.

PMID:
30638424
21.

A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data.

Knapp DJHF, Hammond CA, Wang F, Aghaeepour N, Miller PH, Beer PA, Pellacani D, VanInsberghe M, Hansen C, Bendall SC, Nolan GP, Eaves CJ.

Blood. 2019 Feb 28;133(9):927-939. doi: 10.1182/blood-2018-10-878025. Epub 2019 Jan 8.

22.

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy.

Ghaemi MS, DiGiulio DB, Contrepois K, Callahan B, Ngo TTM, Lee-McMullen B, Lehallier B, Robaczewska A, Mcilwain D, Rosenberg-Hasson Y, Wong RJ, Quaintance C, Culos A, Stanley N, Tanada A, Tsai A, Gaudilliere D, Ganio E, Han X, Ando K, McNeil L, Tingle M, Wise P, Maric I, Sirota M, Wyss-Coray T, Winn VD, Druzin ML, Gibbs R, Darmstadt GL, Lewis DB, Partovi Nia V, Agard B, Tibshirani R, Nolan G, Snyder MP, Relman DA, Quake SR, Shaw GM, Stevenson DK, Angst MS, Gaudilliere B, Aghaeepour N.

Bioinformatics. 2019 Jan 1;35(1):95-103. doi: 10.1093/bioinformatics/bty537.

23.

Complex mammalian-like haematopoietic system found in a colonial chordate.

Rosental B, Kowarsky M, Seita J, Corey DM, Ishizuka KJ, Palmeri KJ, Chen SY, Sinha R, Okamoto J, Mantalas G, Manni L, Raveh T, Clarke DN, Tsai JM, Newman AM, Neff NF, Nolan GP, Quake SR, Weissman IL, Voskoboynik A.

Nature. 2018 Dec;564(7736):425-429. doi: 10.1038/s41586-018-0783-x. Epub 2018 Dec 5.

24.

Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis.

Churko JM, Garg P, Treutlein B, Venkatasubramanian M, Wu H, Lee J, Wessells QN, Chen SY, Chen WY, Chetal K, Mantalas G, Neff N, Jabart E, Sharma A, Nolan GP, Salomonis N, Wu JC.

Nat Commun. 2018 Nov 21;9(1):4906. doi: 10.1038/s41467-018-07333-4.

25.

Practice Guidelines for Standards of Adult Sleep Medicine Services.

Ryan S, Keane S, Nolan G, Purcell E, Cormican L; Irish Sleep Society Committee.

Ir Med J. 2018 Mar 14;111(3):721.

PMID:
30376238
26.

Metal-isotope-tagged monoclonal antibodies for high-dimensional mass cytometry.

Han G, Spitzer MH, Bendall SC, Fantl WJ, Nolan GP.

Nat Protoc. 2018 Oct;13(10):2121-2148. doi: 10.1038/s41596-018-0016-7.

PMID:
30258176
27.

Neurological, Cognitive, and Psychological Findings Among Survivors of Ebola Virus Disease From the 1995 Ebola Outbreak in Kikwit, Democratic Republic of Congo: A Cross-sectional Study.

Kelly JD, Hoff NA, Spencer D, Musene K, Bramble MS, McIlwain D, Okitundu D, Porco TC, Rutherford GW, Glymour MM, Bjornson Z, Mukadi P, Okitolonda-Wemakoy E, Nolan GP, Muyembe-Tamfum JJ, Rimoin AW.

Clin Infect Dis. 2019 Apr 8;68(8):1388-1393. doi: 10.1093/cid/ciy677.

28.

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging.

Goltsev Y, Samusik N, Kennedy-Darling J, Bhate S, Hale M, Vazquez G, Black S, Nolan GP.

Cell. 2018 Aug 9;174(4):968-981.e15. doi: 10.1016/j.cell.2018.07.010. Epub 2018 Aug 2.

29.

MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data.

Hu Z, Jujjavarapu C, Hughey JJ, Andorf S, Lee HC, Gherardini PF, Spitzer MH, Thomas CG, Campbell J, Dunn P, Wiser J, Kidd BA, Dudley JT, Nolan GP, Bhattacharya S, Butte AJ.

Cell Rep. 2018 Jul 31;24(5):1377-1388. doi: 10.1016/j.celrep.2018.07.003.

30.

Three-dimensional intact-tissue sequencing of single-cell transcriptional states.

Wang X, Allen WE, Wright MA, Sylwestrak EL, Samusik N, Vesuna S, Evans K, Liu C, Ramakrishnan C, Liu J, Nolan GP, Bava FA, Deisseroth K.

Science. 2018 Jul 27;361(6400). pii: eaat5691. doi: 10.1126/science.aat5691. Epub 2018 Jun 21.

31.

GateFinder: projection-based gating strategy optimization for flow and mass cytometry.

Aghaeepour N, Simonds EF, Knapp DJHF, Bruggner RV, Sachs K, Culos A, Gherardini PF, Samusik N, Fragiadakis GK, Bendall SC, Gaudilliere B, Angst MS, Eaves CJ, Weiss WA, Fantl WJ, Nolan GP.

Bioinformatics. 2018 Dec 1;34(23):4131-4133. doi: 10.1093/bioinformatics/bty430.

32.

SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia.

Sarno J, Savino AM, Buracchi C, Palmi C, Pinto S, Bugarin C, Jager A, Bresolin S, Barber RC, Silvestri D, Israeli S, Dyer MJS, Cazzaniga G, Nolan GP, Biondi A, Davis KL, Gaipa G.

Oncotarget. 2018 May 1;9(33):22872-22885. doi: 10.18632/oncotarget.25089. eCollection 2018 May 1.

33.

DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity.

Anchang B, Davis KL, Fienberg HG, Williamson BD, Bendall SC, Karacosta LG, Tibshirani R, Nolan GP, Plevritis SK.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4294-E4303. doi: 10.1073/pnas.1711365115. Epub 2018 Apr 13.

34.

The Atacama skeleton.

Nolan G, Butte A.

Genome Res. 2018 May;28(5):607-608. doi: 10.1101/gr.237834.118. Epub 2018 Mar 30. No abstract available.

35.

Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia.

Bhattacharya S, Li J, Sockell A, Kan MJ, Bava FA, Chen SC, Ávila-Arcos MC, Ji X, Smith E, Asadi NB, Lachman RS, Lam HYK, Bustamante CD, Butte AJ, Nolan GP.

Genome Res. 2018 Apr;28(4):423-431. doi: 10.1101/gr.223693.117. Epub 2018 Mar 22.

36.

Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models.

Ajami B, Samusik N, Wieghofer P, Ho PP, Crotti A, Bjornson Z, Prinz M, Fantl WJ, Nolan GP, Steinman L.

Nat Neurosci. 2018 Apr;21(4):541-551. doi: 10.1038/s41593-018-0100-x. Epub 2018 Mar 5.

PMID:
29507414
37.

Publisher Correction: High-resolution myogenic lineage mapping by single-cell mass cytometry.

Porpiglia E, Samusik N, Ho ATV, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM.

Nat Cell Biol. 2018 Aug;20(8):990. doi: 10.1038/s41556-018-0043-1.

PMID:
29507406
38.

Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse.

Good Z, Sarno J, Jager A, Samusik N, Aghaeepour N, Simonds EF, White L, Lacayo NJ, Fantl WJ, Fazio G, Gaipa G, Biondi A, Tibshirani R, Bendall SC, Nolan GP, Davis KL.

Nat Med. 2018 May;24(4):474-483. doi: 10.1038/nm.4505. Epub 2018 Mar 5.

39.

Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry.

Gonzalez VD, Samusik N, Chen TJ, Savig ES, Aghaeepour N, Quigley DA, Huang YW, Giangarrà V, Borowsky AD, Hubbard NE, Chen SY, Han G, Ashworth A, Kipps TJ, Berek JS, Nolan GP, Fantl WJ.

Cell Rep. 2018 Feb 13;22(7):1875-1888. doi: 10.1016/j.celrep.2018.01.053.

40.

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, Levine RL.

Cell Stem Cell. 2018 Feb 1;22(2):277. doi: 10.1016/j.stem.2017.12.018. No abstract available.

41.

Scalable multi-sample single-cell data analysis by Partition-Assisted Clustering and Multiple Alignments of Networks.

Li YH, Li D, Samusik N, Wang X, Guan L, Nolan GP, Wong WH.

PLoS Comput Biol. 2017 Dec 27;13(12):e1005875. doi: 10.1371/journal.pcbi.1005875. eCollection 2017 Dec.

42.

High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.

Alcántara-Hernández M, Leylek R, Wagar LE, Engleman EG, Keler T, Marinkovich MP, Davis MM, Nolan GP, Idoyaga J.

Immunity. 2017 Dec 19;47(6):1037-1050.e6. doi: 10.1016/j.immuni.2017.11.001. Epub 2017 Dec 5.

43.

The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.

44.

Atomic mass tag of bismuth-209 for increasing the immunoassay multiplexing capacity of mass cytometry.

Han G, Chen SY, Gonzalez VD, Zunder ER, Fantl WJ, Nolan GP.

Cytometry A. 2017 Dec;91(12):1150-1163. doi: 10.1002/cyto.a.23283. Epub 2017 Dec 4.

45.

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites.

Dodd D, Spitzer MH, Van Treuren W, Merrill BD, Hryckowian AJ, Higginbottom SK, Le A, Cowan TM, Nolan GP, Fischbach MA, Sonnenburg JL.

Nature. 2017 Nov 30;551(7682):648-652. doi: 10.1038/nature24661. Epub 2017 Nov 22.

46.

Forces generated in stabbing attacks: an evaluation of the utility of the mild, moderate and severe scale.

Nolan G, Hainsworth SV, Rutty GN.

Int J Legal Med. 2018 Jan;132(1):229-236. doi: 10.1007/s00414-017-1702-7. Epub 2017 Oct 16.

47.

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, Levine RL.

Cell Stem Cell. 2017 Oct 5;21(4):489-501.e7. doi: 10.1016/j.stem.2017.08.011. Epub 2017 Sep 28. Erratum in: Cell Stem Cell. 2018 Feb 1;22(2):277.

48.

Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension.

Saito T, Miyagawa K, Chen SY, Tamosiuniene R, Wang L, Sharpe O, Samayoa E, Harada D, Moonen JAJ, Cao A, Chen PI, Hennigs JK, Gu M, Li CG, Leib RD, Li D, Adams CM, Del Rosario PA, Bill M, Haddad F, Montoya JG, Robinson WH, Fantl WJ, Nolan GP, Zamanian RT, Nicolls MR, Chiu CY, Ariza ME, Rabinovitch M.

Circulation. 2017 Nov 14;136(20):1920-1935. doi: 10.1161/CIRCULATIONAHA.117.027589. Epub 2017 Sep 21.

49.

An immune clock of human pregnancy.

Aghaeepour N, Ganio EA, Mcilwain D, Tsai AS, Tingle M, Van Gassen S, Gaudilliere DK, Baca Q, McNeil L, Okada R, Ghaemi MS, Furman D, Wong RJ, Winn VD, Druzin ML, El-Sayed YY, Quaintance C, Gibbs R, Darmstadt GL, Shaw GM, Stevenson DK, Tibshirani R, Nolan GP, Lewis DB, Angst MS, Gaudilliere B.

Sci Immunol. 2017 Sep 1;2(15). pii: eaan2946. doi: 10.1126/sciimmunol.aan2946.

50.

Deep Immune Profiling of an Arginine-Enriched Nutritional Intervention in Patients Undergoing Surgery.

Aghaeepour N, Kin C, Ganio EA, Jensen KP, Gaudilliere DK, Tingle M, Tsai A, Lancero HL, Choisy B, McNeil LS, Okada R, Shelton AA, Nolan GP, Angst MS, Gaudilliere BL.

J Immunol. 2017 Aug 9. pii: ji1700421. doi: 10.4049/jimmunol.1700421. [Epub ahead of print]

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