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Items: 1 to 50 of 194

1.

Exploring Iron Withholding by the Innate Immune Protein Human Calprotectin.

Zygiel EM, Nolan EM.

Acc Chem Res. 2019 Aug 20;52(8):2301-2308. doi: 10.1021/acs.accounts.9b00250. Epub 2019 Aug 5.

PMID:
31381301
2.

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.

Rios AC, Capaldo BD, Vaillant F, Pal B, van Ineveld R, Dawson CA, Chen Y, Nolan E, Fu NY; 3DTCLSM Group, Jackling FC, Devi S, Clouston D, Whitehead L, Smyth GK, Mueller SN, Lindeman GJ, Visvader JE.

Cancer Cell. 2019 Jun 10;35(6):953. doi: 10.1016/j.ccell.2019.05.011. No abstract available.

PMID:
31185217
3.

Murine Calprotectin Coordinates Mn(II) at a Hexahistidine Site with Ca(II)-Dependent Affinity.

Hadley RC, Gagnon DM, Ozarowski A, Britt RD, Nolan EM.

Inorg Chem. 2019 May 30. doi: 10.1021/acs.inorgchem.9b00763. [Epub ahead of print]

PMID:
31145609
4.

High-Field EPR Spectroscopic Characterization of Mn(II) Bound to the Bacterial Solute-Binding Proteins MntC and PsaA.

Gagnon DM, Hadley RC, Ozarowski A, Nolan EM, Britt RD.

J Phys Chem B. 2019 Jun 13;123(23):4929-4934. doi: 10.1021/acs.jpcb.9b03633. Epub 2019 Jun 5.

PMID:
31117618
5.

Diversity and relative abundance of ammonia- and nitrite-oxidizing microorganisms in the offshore Namibian hypoxic zone.

Lau E, Frame CH, Nolan EJ 4th, Stewart FJ, Dillard ZW, Lukich DP, Mihalik NE, Yauch KE, Kinker MA, Waychoff SL.

PLoS One. 2019 May 21;14(5):e0217136. doi: 10.1371/journal.pone.0217136. eCollection 2019.

6.

Predicting the ecological impacts of an alien invader: Experimental approaches reveal the trophic consequences of competition.

Britton JR, Gutmann Roberts C, Amat Trigo F, Nolan ET, De Santis V.

J Anim Ecol. 2019 Jul;88(7):1066-1078. doi: 10.1111/1365-2656.12996. Epub 2019 May 10.

PMID:
30982964
7.

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.

Rios AC, Capaldo BD, Vaillant F, Pal B, van Ineveld R, Dawson CA, Chen Y, Nolan E, Fu NY; 3DTCLSM Group, Jackling FC, Devi S, Clouston D, Whitehead L, Smyth GK, Mueller SN, Lindeman GJ, Visvader JE.

Cancer Cell. 2019 Apr 15;35(4):618-632.e6. doi: 10.1016/j.ccell.2019.02.010. Epub 2019 Mar 28. Erratum in: Cancer Cell. 2019 Jun 10;35(6):953.

PMID:
30930118
8.

Preparation and Iron Redox Speciation Study of the Fe(II)-Binding Antimicrobial Protein Calprotectin.

Hadley RC, Nolan EM.

Methods Mol Biol. 2019;1929:397-415. doi: 10.1007/978-1-4939-9030-6_25.

PMID:
30710287
9.

Preparation of the Oxidized and Reduced Forms of Psoriasin (S100A7).

Cunden LS, Nolan EM.

Methods Mol Biol. 2019;1929:379-395. doi: 10.1007/978-1-4939-9030-6_24.

PMID:
30710286
10.

The human innate immune protein calprotectin induces iron starvation responses in Pseudomonas aeruginosa.

Zygiel EM, Nelson CE, Brewer LK, Oglesby-Sherrouse AG, Nolan EM.

J Biol Chem. 2019 Mar 8;294(10):3549-3562. doi: 10.1074/jbc.RA118.006819. Epub 2019 Jan 8.

PMID:
30622135
11.

A Sensitive, Nonradioactive Assay for Zn(II) Uptake into Metazoan Cells.

Richardson CER, Nolan EM, Shoulders MD, Lippard SJ.

Biochemistry. 2018 Dec 18;57(50):6807-6815. doi: 10.1021/acs.biochem.8b01043. Epub 2018 Dec 5.

PMID:
30381945
12.

Oxidative Post-translational Modifications Accelerate Proteolytic Degradation of Calprotectin.

Stephan JR, Yu F, Costello RM, Bleier BS, Nolan EM.

J Am Chem Soc. 2018 Dec 19;140(50):17444-17455. doi: 10.1021/jacs.8b06354. Epub 2018 Dec 5.

PMID:
30380834
13.

Anorexia Nervosa Complicating Pediatric Crohn Disease-Case Report and Literature Review.

Collins A, Nolan E, Hurley M, D'Alton A, Hussey S.

Front Pediatr. 2018 Oct 9;6:283. doi: 10.3389/fped.2018.00283. eCollection 2018.

14.

Calprotectin influences the aggregation of metal-free and metal-bound amyloid-β by direct interaction.

Lee HJ, Savelieff MG, Kang J, Brophy MB, Nakashige TG, Lee SJC, Nolan EM, Lim MH.

Metallomics. 2018 Aug 15;10(8):1116-1127. doi: 10.1039/c8mt00091c.

PMID:
30046785
15.

Evaluation of a reducible disulfide linker for siderophore-mediated delivery of antibiotics.

Neumann W, Nolan EM.

J Biol Inorg Chem. 2018 Oct;23(7):1025-1036. doi: 10.1007/s00775-018-1588-y. Epub 2018 Jul 2.

PMID:
29968176
16.

Transition Metal Sequestration by the Host-Defense Protein Calprotectin.

Zygiel EM, Nolan EM.

Annu Rev Biochem. 2018 Jun 20;87:621-643. doi: 10.1146/annurev-biochem-062917-012312. Review.

17.

Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site.

Nakashige TG, Bowman SEJ, Zygiel EM, Drennan CL, Nolan EM.

Biochemistry. 2018 Jul 17;57(28):4155-4164. doi: 10.1021/acs.biochem.8b00415. Epub 2018 Jun 26.

18.

Using Co-Design to Develop a Collective Leadership Intervention for Healthcare Teams to Improve Safety Culture.

Ward ME, De Brún A, Beirne D, Conway C, Cunningham U, English A, Fitzsimons J, Furlong E, Kane Y, Kelly A, McDonnell S, McGinley S, Monaghan B, Myler A, Nolan E, O'Donovan R, O'Shea M, Shuhaiber A, McAuliffe E.

Int J Environ Res Public Health. 2018 Jun 5;15(6). pii: E1182. doi: 10.3390/ijerph15061182.

19.

Design, solid-phase synthesis and evaluation of enterobactin analogs for iron delivery into the human pathogen Campylobacter jejuni.

Zamora CY, Madec AGE, Neumann W, Nolan EM, Imperiali B.

Bioorg Med Chem. 2018 Oct 15;26(19):5314-5321. doi: 10.1016/j.bmc.2018.04.030. Epub 2018 Apr 16.

PMID:
29685683
20.

Initial Biochemical and Functional Evaluation of Murine Calprotectin Reveals Ca(II)-Dependence and Its Ability to Chelate Multiple Nutrient Transition Metal Ions.

Hadley RC, Gu Y, Nolan EM.

Biochemistry. 2018 May 15;57(19):2846-2856. doi: 10.1021/acs.biochem.8b00309. Epub 2018 May 2.

21.

First UK case report of kidney transplantation from an HIV-infected deceased donor to two HIV-infected recipients.

Nolan E, Karydis N, Drage M, Hilton R.

Clin Kidney J. 2018 Apr;11(2):289-291. doi: 10.1093/ckj/sfx109. Epub 2017 Sep 18.

22.

Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity.

Neumann W, Sassone-Corsi M, Raffatellu M, Nolan EM.

J Am Chem Soc. 2018 Apr 18;140(15):5193-5201. doi: 10.1021/jacs.8b01042. Epub 2018 Apr 10.

23.

Bioinorganic Explorations of Zn(II) Sequestration by Human S100 Host-Defense Proteins.

Cunden LS, Nolan EM.

Biochemistry. 2018 Mar 20;57(11):1673-1680. doi: 10.1021/acs.biochem.7b01305. Epub 2018 Mar 6.

24.

A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency.

Richardson CER, Cunden LS, Butty VL, Nolan EM, Lippard SJ, Shoulders MD.

J Am Chem Soc. 2018 Feb 21;140(7):2413-2416. doi: 10.1021/jacs.7b12897. Epub 2018 Feb 12.

25.

Biochemical and Spectroscopic Observation of Mn(II) Sequestration from Bacterial Mn(II) Transport Machinery by Calprotectin.

Hadley RC, Gagnon DM, Brophy MB, Gu Y, Nakashige TG, Britt RD, Nolan EM.

J Am Chem Soc. 2018 Jan 10;140(1):110-113. doi: 10.1021/jacs.7b11207. Epub 2017 Dec 20.

26.

A Noncanonical Role for Yersiniabactin in Bacterial Copper Acquisition.

Nolan EM.

Biochemistry. 2017 Nov 21;56(46):6073-6074. doi: 10.1021/acs.biochem.7b01003. Epub 2017 Nov 7. Review. No abstract available.

PMID:
29111683
27.

Life-history strategies of the rock hind grouper Epinephelus adscensionis at Ascension Island.

Nolan ET, Downes KJ, Richardson A, Arkhipkin A, Brickle P, Brown J, Mrowicki RJ, Shcherbich Z, Weber N, Weber SB.

J Fish Biol. 2017 Dec;91(6):1549-1568. doi: 10.1111/jfb.13410. Epub 2017 Oct 25.

PMID:
29068043
28.

Biochemical and Functional Evaluation of the Intramolecular Disulfide Bonds in the Zinc-Chelating Antimicrobial Protein Human S100A7 (Psoriasin).

Cunden LS, Brophy MB, Rodriguez GE, Flaxman HA, Nolan EM.

Biochemistry. 2017 Oct 31;56(43):5726-5738. doi: 10.1021/acs.biochem.7b00781. Epub 2017 Oct 19.

29.

Determination of the Molecular Structures of Ferric Enterobactin and Ferric Enantioenterobactin Using Racemic Crystallography.

Johnstone TC, Nolan EM.

J Am Chem Soc. 2017 Oct 25;139(42):15245-15250. doi: 10.1021/jacs.7b09375. Epub 2017 Oct 17.

30.

Expression and function of spineless orthologs correlate with distal deutocerebral appendage morphology across Arthropoda.

Setton EVW, March LE, Nolan ED, Jones TE, Cho H, Wheeler WC, Extavour CG, Sharma PP.

Dev Biol. 2017 Oct 1;430(1):224-236. doi: 10.1016/j.ydbio.2017.07.016. Epub 2017 Jul 29.

31.

Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.

Nolan E, Savas P, Policheni AN, Darcy PK, Vaillant F, Mintoff CP, Dushyanthen S, Mansour M, Pang JB, Fox SB; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab), Perou CM, Visvader JE, Gray DHD, Loi S, Lindeman GJ.

Sci Transl Med. 2017 Jun 7;9(393). pii: eaal4922. doi: 10.1126/scitranslmed.aal4922.

32.

Nickel Sequestration by the Host-Defense Protein Human Calprotectin.

Nakashige TG, Zygiel EM, Drennan CL, Nolan EM.

J Am Chem Soc. 2017 Jul 5;139(26):8828-8836. doi: 10.1021/jacs.7b01212. Epub 2017 Jun 22.

33.

Human calprotectin affects the redox speciation of iron.

Nakashige TG, Nolan EM.

Metallomics. 2017 Aug 16;9(8):1086-1095. doi: 10.1039/c7mt00044h.

34.

Transition metals at the host-pathogen interface: how Neisseria exploit human metalloproteins for acquiring iron and zinc.

Neumann W, Hadley RC, Nolan EM.

Essays Biochem. 2017 May 9;61(2):211-223. doi: 10.1042/EBC20160084. Print 2017 May 9. Review.

35.

Magnetic circular dichroism studies of iron(ii) binding to human calprotectin.

Baker TM, Nakashige TG, Nolan EM, Neidig ML.

Chem Sci. 2017 Feb 1;8(2):1369-1377. doi: 10.1039/c6sc03487j. Epub 2016 Oct 11.

36.

RE: Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.

Nolan E, Vaillant F, Visvader JE, Lindeman GJ.

J Natl Cancer Inst. 2017 Oct 1;109(10). doi: 10.1093/jnci/djx038. No abstract available.

PMID:
28383640
37.

Human α-Defensin 6: A Small Peptide That Self-Assembles and Protects the Host by Entangling Microbes.

Chairatana P, Nolan EM.

Acc Chem Res. 2017 Apr 18;50(4):960-967. doi: 10.1021/acs.accounts.6b00653. Epub 2017 Mar 15. Review.

38.

Validation of temporal gait metrics from three IMU locations to the gold standard force plate.

Patterson MR, Johnston W, O'Mahony N, O'Mahony S, Nolan E, Caulfield B.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:667-671. doi: 10.1109/EMBC.2016.7590790.

PMID:
28268416
39.

Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.

Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G.

J Clin Invest. 2017 Mar 1;127(3):830-842. doi: 10.1172/JCI87583. Epub 2017 Jan 30.

40.

Acidification Enhances Hybrid N2O Production Associated with Aquatic Ammonia-Oxidizing Microorganisms.

Frame CH, Lau E, Nolan EJ 4th, Goepfert TJ, Lehmann MF.

Front Microbiol. 2017 Jan 9;7:2104. doi: 10.3389/fmicb.2016.02104. eCollection 2016.

41.

Out-RANKing BRCA1 in Mutation Carriers.

Nolan E, Lindeman GJ, Visvader JE.

Cancer Res. 2017 Feb 1;77(3):595-600. doi: 10.1158/0008-5472.CAN-16-2025. Epub 2017 Jan 19. Review.

42.

Human α-Defensin 6 Self-Assembly Prevents Adhesion and Suppresses Virulence Traits of Candida albicans.

Chairatana P, Chiang IL, Nolan EM.

Biochemistry. 2017 Feb 28;56(8):1033-1041. doi: 10.1021/acs.biochem.6b01111. Epub 2017 Jan 23.

PMID:
28026958
43.

Metal homeostasis in infectious disease: recent advances in bacterial metallophores and the human metal-withholding response.

Neumann W, Gulati A, Nolan EM.

Curr Opin Chem Biol. 2017 Apr;37:10-18. doi: 10.1016/j.cbpa.2016.09.012. Epub 2016 Dec 18. Review.

44.

Evolvix BEST Names for semantic reproducibility across code2brain interfaces.

Loewe L, Scheuer KS, Keel SA, Vyas V, Liblit B, Hanlon B, Ferris MC, Yin J, Dutra I, Pietsch A, Javid CG, Moog CL, Meyer J, Dresel J, McLoone B, Loberger S, Movaghar A, Gilchrist-Scott M, Sabri Y, Sescleifer D, Pereda-Zorrilla I, Zietlow A, Smith R, Pietenpol S, Goldfinger J, Atzen SL, Freiberg E, Waters NP, Nusbaum C, Nolan E, Hotz A, Kliman RM, Mentewab A, Fregien N, Loewe M.

Ann N Y Acad Sci. 2017 Jan;1387(1):124-144. doi: 10.1111/nyas.13192. Epub 2016 Dec 5. Review.

45.

Inflammatory biomarkers are associated with ketosis in periparturient Holstein cows.

Abuajamieh M, Kvidera SK, Fernandez MV, Nayeri A, Upah NC, Nolan EA, Lei SM, DeFrain JM, Green HB, Schoenberg KM, Trout WE, Baumgard LH.

Res Vet Sci. 2016 Dec;109:81-85. doi: 10.1016/j.rvsc.2016.09.015. Epub 2016 Sep 21.

PMID:
27892878
46.

Addressing the needs of Nicaraguan older adults living on the edge: A university-community partnership in international service-learning.

Neal MB, Cannon M, DeLaTorre A, Bolkan CR, Wernher I, Nolan E, López Norori M, Largaespada-Fredersdorff C, Brown Wilson K.

Gerontol Geriatr Educ. 2017 Jan-Mar;38(1):119-138. doi: 10.1080/02701960.2016.1259161. Epub 2016 Nov 28.

PMID:
27892805
47.

Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut.

Chairatana P, Nolan EM.

Crit Rev Biochem Mol Biol. 2017 Feb;52(1):45-56. doi: 10.1080/10409238.2016.1243654. Epub 2016 Nov 13. Review.

48.

Siderophore-based immunization strategy to inhibit growth of enteric pathogens.

Sassone-Corsi M, Chairatana P, Zheng T, Perez-Lopez A, Edwards RA, George MD, Nolan EM, Raffatellu M.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13462-13467. Epub 2016 Nov 7.

49.

The scientific agreement on firearm issues.

Hemenway D, Nolan EP.

Inj Prev. 2017 Aug;23(4):221-225. doi: 10.1136/injuryprev-2016-042146. Epub 2016 Oct 6.

PMID:
27758830
50.

Fears and Misperceptions of the Ebola Response System during the 2014-2015 Outbreak in Sierra Leone.

Yamanis T, Nolan E, Shepler S.

PLoS Negl Trop Dis. 2016 Oct 18;10(10):e0005077. doi: 10.1371/journal.pntd.0005077. eCollection 2016 Oct.

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