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Items: 1 to 50 of 403

1.

Structural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.

Ohbayashi N, Murayama K, Kato-Murayama M, Kukimoto-Niino M, Uejima T, Matsuda T, Ohsawa N, Yokoyoma S, Nojima H, Shirouzu M.

ChemistryOpen. 2018 Sep 10;7(9):721-727. doi: 10.1002/open.201800177. eCollection 2018 Sep.

2.

Conversion surgery with gemcitabine plus nab-paclitaxel for locally advanced unresectable pancreatic cancer: A case report.

Okura R, Takano S, Yokota T, Yoshitomi H, Kagawa S, Furukawa K, Takayashiki T, Kuboki S, Suzuki D, Sakai N, Nojima H, Mishima T, Miyazaki M, Ohtsuka M.

Mol Clin Oncol. 2018 Oct;9(4):389-393. doi: 10.3892/mco.2018.1688. Epub 2018 Aug 1.

3.

Ficolin-1 is a promising therapeutic target for autoimmune diseases.

Katayama M, Ota K, Nagi-Miura N, Ohno N, Yabuta N, Nojima H, Kumanogoh A, Hirano T.

Int Immunol. 2018 Aug 28. doi: 10.1093/intimm/dxy056. [Epub ahead of print]

PMID:
30169661
4.

Peripheral gabapentin regulates mosquito allergy-induced itch in mice.

Akiyama T, Andoh T, Ohtsuka E, Nojima H, Ouchi H, Takahata H, Kuraishi Y.

Eur J Pharmacol. 2018 Aug 15;833:44-49. doi: 10.1016/j.ejphar.2018.05.037. Epub 2018 May 26.

PMID:
29842875
5.

Novel treatment strategy with radiofrequency ablation and surgery for pregnant patients with hepatocellular carcinoma: a case report.

Matsuo M, Furukawa K, Shimizu H, Yoshitomi H, Takayashiki T, Kuboki S, Takano S, Suzuki D, Sakai N, Kagawa S, Nojima H, Ohsuka M.

Surg Case Rep. 2018 May 2;4(1):43. doi: 10.1186/s40792-018-0434-3.

6.

Glucagonoma With Necrolytic Migratory Erythema: Metabolic Profile and Detection of Biallelic Inactivation of DAXX Gene.

Tamura A, Ogasawara T, Fujii Y, Kaneko H, Nakayama A, Higuchi S, Hashimoto N, Miyabayashi Y, Fujimoto M, Komai E, Kono T, Sakuma I, Nagano H, Suzuki S, Koide H, Yokote K, Iseki K, Oguma R, Matsue H, Nojima H, Sugiura K, Yoshitomi H, Ohtsuka M, Rahmutulla B, Kaneda A, Inoshita N, Ogawa S, Tanaka T.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2417-2423. doi: 10.1210/jc.2017-02646.

PMID:
29688432
7.

Nanomolar Determination of Hydrogen Peroxide in Coastal Seawater Based on the Fenton Reaction with Terephthalate.

Takeda K, Nojima H, Kuwahara K, Chidya RC, Adesina AO, Sakugawa H.

Anal Sci. 2018;34(4):459-464. doi: 10.2116/analsci.17P536.

8.

Late cornified envelope 1C (LCE1C), a transcriptional target of TAp63 phosphorylated at T46/T281, interacts with PRMT5.

Yabuta N, Ota C, Sasakura T, Naito Y, Okuzaki D, Fukushima K, Nojima H.

Sci Rep. 2018 Mar 20;8(1):4892. doi: 10.1038/s41598-018-23045-7.

9.

Physiological and molecular effects of interleukin-18 administration on the mouse kidney.

Yamanishi K, Mukai K, Hashimoto T, Ikubo K, Nakasho K, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Hayakawa T, Nojima H, Yamanishi H, Okamura H, Matsunaga H.

J Transl Med. 2018 Mar 7;16(1):51. doi: 10.1186/s12967-018-1426-6.

10.

ELAS1 induces apoptotic death in adenocarcinoma DU145 and squamous-cell carcinoma SAS cancer cells, but not in normal KD cells.

Uchihashi T, Ota K, Yabuno Y, Ohno S, Fukushima K, Naito Y, Kogo M, Yabuta N, Nojima H.

Oncotarget. 2017 Aug 24;8(49):85868-85882. doi: 10.18632/oncotarget.20696. eCollection 2017 Oct 17.

11.

[IV. Distal Pancreatectomy with Celiac Axis Resection(DP-CAR)for Locally Advanced Pancreatic Cancer with Celiac Artery Invasion].

Yoshitomi H, Sakai N, Ueda A, Furukawa K, Takayashiki T, Kuboki S, Takano S, Suzuki D, Kagawa S, Nojima H, Mishima T, Miyazaki M, Ohtsuka M.

Gan To Kagaku Ryoho. 2017 Oct;44(10):854-859. Japanese. No abstract available.

PMID:
29066679
12.

FCN1 (M-ficolin), which directly associates with immunoglobulin G1, is a molecular target of intravenous immunoglobulin therapy for Kawasaki disease.

Okuzaki D, Ota K, Takatsuki SI, Akiyoshi Y, Naoi K, Yabuta N, Saji T, Nojima H.

Sci Rep. 2017 Sep 12;7(1):11334. doi: 10.1038/s41598-017-11108-0.

13.

Association between aerobic capacity and the improvement in glycemic control after the exercise training in type 2 diabetes.

Nojima H, Yoneda M, Watanabe H, Yamane K, Kitahara Y, Sekikawa K, Yamamoto H, Yokoyama A, Hattori N, Kohno N; Hiroshima University Health Promotion Study group.

Diabetol Metab Syndr. 2017 Aug 18;9:63. doi: 10.1186/s13098-017-0262-9. eCollection 2017.

14.

[III .ALPPS Up to Date].

Sakai N, Shimizu H, Ohtsuka M, Yoshitomi H, Furukawa K, Takayashiki T, Takano S, Kuboki S, Suzuki D, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2016 Oct;43(10):1181-1185. Japanese. No abstract available.

PMID:
28676606
15.

Duffy antigen receptor for chemokines (DARC) expressing in cancer cells inhibits tumor progression by suppressing CXCR2 signaling in human pancreatic ductal adenocarcinoma.

Maeda S, Kuboki S, Nojima H, Shimizu H, Yoshitomi H, Furukawa K, Miyazaki M, Ohtsuka M.

Cytokine. 2017 Jul;95:12-21. doi: 10.1016/j.cyto.2017.02.007. Epub 2017 Feb 20.

PMID:
28214673
16.

GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase.

Fukushima K, Wang M, Naito Y, Uchihashi T, Kato Y, Mukai S, Yabuta N, Nojima H.

Cell Cycle. 2017 Mar 4;16(5):415-427. doi: 10.1080/15384101.2016.1241916. Epub 2017 Jan 31.

17.

[A Case of Early-Onset Rapidly Progressive Cerebral Infarction with Trousseau's Syndrome in a Patient with Pancreatic Cancer Undergoing Surgery].

Yogi N, Nojima H, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takayashiki T, Takano S, Kuboki S, Suzuki D, Sakai N, Kagawa S, Miyazaki M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):1985-1987. Japanese.

PMID:
28133197
18.

[A Radically-Resected Case of Ruptured IPMC of the Pancreas after Abscess Drainage Using an Endoscopic Naso-Pancreatic Drainage Tube].

Furukawa A, Kuboki S, Shimizu H, Ohtsuka M, Yoshitomi H, Furukawa K, Takayashiki T, Takano S, Suzuki D, Sakai N, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):1969-1971. Japanese.

PMID:
28133192
19.

[A Rare Complication of Transcatheter Arterial Injection for Multiple Liver Metastases of Rectal Neuroendocrine Tumor - A Case Report].

Suzuki K, Sakai N, Shimizu H, Ohtsuka M, Yoshitomi H, Furukawa K, Takayashiki T, Kuboki S, Takano S, Suzuki D, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):1791-1793. Japanese.

PMID:
28133133
20.

[Two Cases of Remnant Pancreatic Cancer Treated Using Remnant Pancreatectomy Combined with Hepatic Arterial Resection].

Ueda A, Sakai N, Yoshitomi H, Shimizu H, Ohtsuka M, Kato A, Furukawa K, Takayashiki T, Takano S, Kuboki S, Suzuki D, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):1665-1667. Japanese.

PMID:
28133092
21.

Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2.

Ohno S, Ikeda JI, Naito Y, Okuzaki D, Sasakura T, Fukushima K, Nishikawa Y, Ota K, Kato Y, Wang M, Torigata K, Kasama T, Uchihashi T, Miura D, Yabuta N, Morii E, Nojima H.

Sci Rep. 2016 Dec 16;6:39091. doi: 10.1038/srep39091.

22.

Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes.

Nojima H, Konishi T, Freeman CM, Schuster RM, Japtok L, Kleuser B, Edwards MJ, Gulbins E, Lentsch AB.

PLoS One. 2016 Aug 23;11(8):e0161443. doi: 10.1371/journal.pone.0161443. eCollection 2016.

23.

Large tumor suppressors 1 and 2 regulate Aurora-B through phosphorylation of INCENP to ensure completion of cytokinesis.

Yabuta N, Yoshida K, Mukai S, Kato Y, Torigata K, Nojima H.

Heliyon. 2016 Jul 20;2(7):e00131. doi: 10.1016/j.heliyon.2016.e00131. eCollection 2016 Jul.

24.

Comprehensive analysis of the Co-structures of dipeptidyl peptidase IV and its inhibitor.

Nojima H, Kanou K, Terashi G, Takeda-Shitaka M, Inoue G, Atsuda K, Itoh C, Iguchi C, Matsubara H.

BMC Struct Biol. 2016 Aug 5;16:11. doi: 10.1186/s12900-016-0062-8.

25.

AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol.

Jagannathan R, Schimizzi GV, Zhang K, Loza AJ, Yabuta N, Nojima H, Longmore GD.

Mol Cell Biol. 2016 Sep 26;36(20):2526-42. doi: 10.1128/MCB.00136-16. Print 2016 Oct 15.

26.

Activation of peroxisome proliferator-activated receptor-gamma inhibits tumor growth by negatively regulating nuclear factor-κB activation in patients with hepatocellular carcinoma.

Nojima H, Kuboki S, Shinoda K, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takayashiki T, Miyazaki M.

J Hepatobiliary Pancreat Sci. 2016 Sep;23(9):574-84. doi: 10.1002/jhbp.378. Epub 2016 Aug 16.

PMID:
27451128
27.

LATS2 Positively Regulates Polycomb Repressive Complex 2.

Torigata K, Daisuke O, Mukai S, Hatanaka A, Ohka F, Motooka D, Nakamura S, Ohkawa Y, Yabuta N, Kondo Y, Nojima H.

PLoS One. 2016 Jul 19;11(7):e0158562. doi: 10.1371/journal.pone.0158562. eCollection 2016.

28.

The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila.

Wang Z, Tian A, Benchabane H, Tacchelly-Benites O, Yang E, Nojima H, Ahmed Y.

Development. 2016 May 15;143(10):1710-20. doi: 10.1242/dev.127647.

29.

IFI27 Is a Useful Genetic Marker for Diagnosis of Immunoglobulin A Nephropathy and Membranous Nephropathy Using Peripheral Blood.

Nagasawa Y, Okuzaki D, Muso E, Yamamoto R, Shinzawa M, Iwasaki Y, Iwatani H, Nakanishi T, Isaka Y, Nojima H.

PLoS One. 2016 Apr 21;11(4):e0153252. doi: 10.1371/journal.pone.0153252. eCollection 2016.

30.

Interleukin-18-deficient mice develop dyslipidemia resulting in nonalcoholic fatty liver disease and steatohepatitis.

Yamanishi K, Maeda S, Kuwahara-Otani S, Watanabe Y, Yoshida M, Ikubo K, Okuzaki D, El-Darawish Y, Li W, Nakasho K, Nojima H, Yamanishi H, Hayakawa T, Okamura H, Matsunaga H.

Transl Res. 2016 Jul;173:101-114.e7. doi: 10.1016/j.trsl.2016.03.010. Epub 2016 Mar 19.

PMID:
27063959
31.

Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.

Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y.

Genetics. 2016 May;203(1):269-81. doi: 10.1534/genetics.115.183244. Epub 2016 Mar 14.

32.

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.

Anvarian Z, Nojima H, van Kappel EC, Madl T, Spit M, Viertler M, Jordens I, Low TY, van Scherpenzeel RC, Kuper I, Richter K, Heck AJ, Boelens R, Vincent JP, Rüdiger SG, Maurice MM.

Nat Struct Mol Biol. 2016 Apr;23(4):324-32. doi: 10.1038/nsmb.3191. Epub 2016 Mar 14.

PMID:
26974125
33.

Effects of 1-cyclohexyl- and 1-cyclohexyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on dopaminergic spontaneous discharge in nigral neurons of rats.

Abe M, Munakata H, Abe K, Saito T, Horiguchi Y, Nojima H, Taguchi K.

Brain Res Bull. 2016 Mar;121:201-8. doi: 10.1016/j.brainresbull.2016.02.007. Epub 2016 Feb 10.

PMID:
26876935
34.

[Surgical Resection for Mediastinal Lymph Node Metastasis of Combined Hepatocellular and Cholangiocarcinoma--A Case Report].

Yoshida M, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takayashiki T, Kuboki S, Takano S, Okamura D, Suzuki D, Sakai N, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2015 Nov;42(12):1857-9. Japanese.

PMID:
26805196
35.

[Peritoneovenous Shunting as a Palliative Therapy for Refractory Ascites after Biliary Cancer Surgery].

Miyauchi Y, Takayashiki T, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takano S, Kuboki S, Suzuki D, Sakai N, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2015 Nov;42(12):1550-2. Japanese.

PMID:
26805092
36.

Microarray and whole-exome sequencing analysis of familial Behçet's disease patients.

Okuzaki D, Yoshizaki K, Tanaka T, Hirano T, Fukushima K, Washio T, Nojima H.

Sci Rep. 2016 Jan 20;6:19456. doi: 10.1038/srep19456.

37.

Cyclin G2: A novel independent prognostic marker in pancreatic cancer.

Hasegawa S, Nagano H, Konno M, Eguchi H, Tomokuni A, Tomimaru Y, Wada H, Hama N, Kawamoto K, Kobayashi S, Marubashi S, Nishida N, Koseki J, Gotoh N, Ohno S, Yabuta N, Nojima H, Mori M, Doki Y, Ishii H.

Oncol Lett. 2015 Nov;10(5):2986-2990. Epub 2015 Sep 2.

38.

[III. Repeat pancreatectomy for recurrent pancreatic cancer].

Yoshitomi H, Shimizu H, Ohtsuka M, Kato A, Furukawa K, Takayashiki T, Kuboki S, Takano S, Suzuki D, Sakai N, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2015 Oct;42(10):1173-7. Japanese. No abstract available.

PMID:
26665417
39.

Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.

Mukai S, Yabuta N, Yoshida K, Okamoto A, Miura D, Furuta Y, Abe T, Nojima H.

Sci Rep. 2015 Nov 4;5:16173. doi: 10.1038/srep16173.

40.

Effects of low-fat diet and aging on metabolic profiles of Creb3l4 knockout mice.

Kim TH, Park JM, Jo SH, Kim MY, Nojima H, Ahn YH.

Nutr Diabetes. 2015 Aug 24;5:e179. doi: 10.1038/nutd.2015.29.

41.

Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate.

Nojima H, Freeman CM, Schuster RM, Japtok L, Kleuser B, Edwards MJ, Gulbins E, Lentsch AB.

J Hepatol. 2016 Jan;64(1):60-8. doi: 10.1016/j.jhep.2015.07.030. Epub 2015 Aug 5.

42.

Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells.

Nishikawa Y, Okuzaki D, Fukushima K, Mukai S, Ohno S, Ozaki Y, Yabuta N, Nojima H.

PLoS One. 2015 Jul 31;10(7):e0134137. doi: 10.1371/journal.pone.0134137. eCollection 2015.

43.

Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the kidneys.

Watanabe Y, Yoshida M, Yamanishi K, Yamamoto H, Okuzaki D, Nojima H, Yasunaga T, Okamura H, Matsunaga H, Yamanishi H.

Int J Mol Med. 2015 Sep;36(3):712-24. doi: 10.3892/ijmm.2015.2281. Epub 2015 Jul 10.

44.

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.

Chen Q, Zhang N, Xie R, Wang W, Cai J, Choi KS, David KK, Huang B, Yabuta N, Nojima H, Anders RA, Pan D.

Genes Dev. 2015 Jun 15;29(12):1285-97. doi: 10.1101/gad.264234.115.

45.

Additional donepezil treatment for patients with geriatric depression who exhibit cognitive deficit during treatment for depression.

Inoue J, Hoshino R, Nojima H, Ishida W, Okamoto N.

Psychogeriatrics. 2016 Jan;16(1):54-61. doi: 10.1111/psyg.12121. Epub 2015 Apr 27.

46.

ELAS1-mediated inhibition of the cyclin G1-B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53.

Ohno S, Naito Y, Mukai S, Yabuta N, Nojima H.

Oncogene. 2015 Dec 3;34(49):5983-96. doi: 10.1038/onc.2015.47. Epub 2015 Apr 27.

PMID:
25915850
47.

Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis.

Okamoto A, Yabuta N, Mukai S, Torigata K, Nojima H.

Cell Cycle. 2015;14(10):1568-82. doi: 10.1080/15384101.2015.1026489.

48.

Sphingolipids in liver injury, repair and regeneration.

Nojima H, Freeman CM, Gulbins E, Lentsch AB.

Biol Chem. 2015 Jun;396(6-7):633-43. doi: 10.1515/hsz-2014-0296. Review.

PMID:
25781682
49.

CXC chemokines function as a rheostat for hepatocyte proliferation and liver regeneration.

Wilson GC, Kuboki S, Freeman CM, Nojima H, Schuster RM, Edwards MJ, Lentsch AB.

PLoS One. 2015 Mar 10;10(3):e0120092. doi: 10.1371/journal.pone.0120092. eCollection 2015.

50.

CXC chemokine receptor-4 signaling limits hepatocyte proliferation after hepatic ischemia-reperfusion in mice.

Wilson GC, Freeman CM, Kuethe JW, Quillin RC 3rd, Nojima H, Schuster R, Blanchard J, Edwards MJ, Caldwell CC, Lentsch AB.

Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15;308(8):G702-9. doi: 10.1152/ajpgi.00257.2014. Epub 2015 Feb 26.

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