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Items: 1 to 50 of 95

1.

Identification of 15 T Cell Restricted Genes Evaluates T Cell Infiltration of Human Healthy Tissues and Cancers and Shows Prognostic and Predictive Potential.

Cari L, De Rosa F, Petrillo MG, Migliorati G, Nocentini G, Riccardi C.

Int J Mol Sci. 2019 Oct 22;20(20). pii: E5242. doi: 10.3390/ijms20205242.

2.

Novel Immune Targets in Melanoma-Letter.

Nocentini G, Cari L, Riccardi C.

Clin Cancer Res. 2019 Sep 1;25(17):5422-5423. doi: 10.1158/1078-0432.CCR-19-1140. No abstract available.

PMID:
31481484
3.

The first-generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue.

Zucchi A, Costantini E, Scroppo FI, Silvani M, Kopa Z, Illiano E, Petrillo MG, Cari L, Nocentini G.

Andrology. 2019 Nov;7(6):804-817. doi: 10.1111/andr.12683. Epub 2019 Jul 26. Review.

4.

Engineered Alginate Microcapsules for Molecular Therapy Through Biologic Secreting Cells.

Montanucci P, Cari L, Basta G, Pescara T, Riccardi C, Nocentini G, Calafiore R.

Tissue Eng Part C Methods. 2019 May;25(5):296-304. doi: 10.1089/ten.TEC.2018.0329.

PMID:
30950315
5.
6.

Beta-carotene, telomerase activity and Alzheimer's disease in old age subjects.

Boccardi V, Arosio B, Cari L, Bastiani P, Scamosci M, Casati M, Ferri E, Bertagnoli L, Ciccone S, Rossi PD, Nocentini G, Mecocci P.

Eur J Nutr. 2019 Jan 16. doi: 10.1007/s00394-019-01892-y. [Epub ahead of print]

PMID:
30649596
7.

Telomeres Increasingly Develop Aberrant Structures in Aging Humans.

Boccardi V, Cari L, Nocentini G, Riccardi C, Cecchetti R, Ruggiero C, Arosio B, Paolisso G, Herbig U, Mecocci P.

J Gerontol A Biol Sci Med Sci. 2018 Nov 2. doi: 10.1093/gerona/gly257. [Epub ahead of print]

PMID:
30388200
8.

Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper.

Roth-Walter F, Adcock IM, Benito-Villalvilla C, Bianchini R, Bjermer L, Caramori G, Cari L, Chung KF, Diamant Z, Eguiluz-Gracia I, Knol EF, Kolios AGA, Levi-Schaffer F, Nocentini G, Palomares O, Puzzovio PG, Redegeld FA, van Esch BCAM, Stellato C.

Allergy. 2019 Mar;74(3):432-448. doi: 10.1111/all.13642. Epub 2019 Jan 8.

9.

Glucocorticoid-induced TNFR-related gene (GITR) as a therapeutic target for immunotherapy.

Riccardi C, Ronchetti S, Nocentini G.

Expert Opin Ther Targets. 2018 Sep;22(9):783-797. doi: 10.1080/14728222.2018.1512588. Epub 2018 Aug 23. Review.

PMID:
30107134
10.

Potential effect of tumor-specific Treg-targeted antibodies in the treatment of human cancers: A bioinformatics analysis.

Cari L, Nocentini G, Migliorati G, Riccardi C.

Oncoimmunology. 2017 Nov 9;7(2):e1387705. doi: 10.1080/2162402X.2017.1387705. eCollection 2018.

11.

Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy.

Ludovini V, Antognelli C, Rulli A, Foglietta J, Pistola L, Eliana R, Floriani I, Nocentini G, Tofanetti FR, Piattoni S, Minenza E, Talesa VN, Sidoni A, Tonato M, Crinò L, Gori S.

BMC Cancer. 2017 Jul 26;17(1):502. doi: 10.1186/s12885-017-3483-2.

12.

The Proinflammatory Cytokine GITRL Contributes to TRAIL-mediated Neurotoxicity in the HCN-2 Human Neuronal Cell Line.

Benedetto GD, Saccone S, Lempereur L, Ronsisvalle N, Nocentini G, Bianchini R, Riccardi C, Bernardini R, Cantarella G.

Curr Alzheimer Res. 2017;14(10):1090-1101. doi: 10.2174/1567205014666170519113912.

PMID:
28524007
13.

The role of GITR single-positive cells in immune homeostasis.

Nocentini G, Cari L, Migliorati G, Riccardi C.

Immun Inflamm Dis. 2017 Feb 23;5(1):4-6. doi: 10.1002/iid3.148. eCollection 2017 Mar. No abstract available.

14.

Waning of vaccine-induced immunity to measles in kidney transplanted children.

Rocca S, Santilli V, Cotugno N, Concato C, Manno EC, Nocentini G, Macchiarulo G, Cancrini C, Finocchi A, Guzzo I, Dello Strologo L, Palma P.

Medicine (Baltimore). 2016 Sep;95(37):e4738. doi: 10.1097/MD.0000000000004738.

15.

A focused Real Time PCR strategy to determine GILZ expression in mouse tissues.

Cari L, Ricci E, Gentili M, Petrillo MG, Ayroldi E, Ronchetti S, Nocentini G, Riccardi C.

Results Immunol. 2015 Oct 21;5:37-42. doi: 10.1016/j.rinim.2015.10.003. eCollection 2015.

16.

Modulation of tumor immunity: a patent evaluation of WO2015026684A1.

Nocentini G, Cari L, Ronchetti S, Riccardi C.

Expert Opin Ther Pat. 2016;26(3):417-25. doi: 10.1517/13543776.2016.1118061. Epub 2016 Feb 15.

PMID:
26560753
17.

Glucocorticoid-induced tumour necrosis factor receptor-related protein: a key marker of functional regulatory T cells.

Ronchetti S, Ricci E, Petrillo MG, Cari L, Migliorati G, Nocentini G, Riccardi C.

J Immunol Res. 2015;2015:171520. doi: 10.1155/2015/171520. Epub 2015 Apr 15. Review.

18.

GITR+ regulatory T cells in the treatment of autoimmune diseases.

Petrillo MG, Ronchetti S, Ricci E, Alunno A, Gerli R, Nocentini G, Riccardi C.

Autoimmun Rev. 2015 Feb;14(2):117-26. doi: 10.1016/j.autrev.2014.10.011. Epub 2014 Oct 14. Review.

PMID:
25449679
19.

Expansion of regulatory GITR+CD25 low/-CD4+ T cells in systemic lupus erythematosus patients.

Nocentini G, Alunno A, Petrillo MG, Bistoni O, Bartoloni E, Caterbi S, Ronchetti S, Migliorati G, Riccardi C, Gerli R.

Arthritis Res Ther. 2014 Sep 26;16(5):444. doi: 10.1186/s13075-014-0444-x.

20.

L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells.

Ayroldi E, Petrillo MG, Bastianelli A, Marchetti MC, Ronchetti S, Nocentini G, Ricciotti L, Cannarile L, Riccardi C.

Cell Death Differ. 2015 Jan;22(1):118-30. doi: 10.1038/cdd.2014.129. Epub 2014 Aug 29.

21.

Transcriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids.

Petrillo MG, Fettucciari K, Montuschi P, Ronchetti S, Cari L, Migliorati G, Mazzon E, Bereshchenko O, Bruscoli S, Nocentini G, Riccardi C.

BMC Pharmacol Toxicol. 2014 Jul 3;15:35. doi: 10.1186/2050-6511-15-35.

22.

Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells.

Ceccarelli V, Nocentini G, Billi M, Racanicchi S, Riccardi C, Roberti R, Grignani F, Binaglia L, Vecchini A.

PLoS One. 2014 Jan 13;9(1):e85025. doi: 10.1371/journal.pone.0085025. eCollection 2014.

23.

Characterization of CD4+ and CD8+ Tregs in a Hodgkin's lymphoma patient presenting with myasthenia-like symptoms.

Krausz LT, Major ZZ, Muresanu DF, Chelaru E, Nocentini G, Riccardi C.

Ideggyogy Sz. 2013 Sep 30;66(9-10):343-8.

PMID:
24358691
24.

Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion.

Lacal PM, Petrillo MG, Ruffini F, Muzi A, Bianchini R, Ronchetti S, Migliorati G, Riccardi C, Graziani G, Nocentini G.

J Pharmacol Exp Ther. 2013 Oct;347(1):164-72. doi: 10.1124/jpet.113.207605. Epub 2013 Jul 26.

PMID:
23892569
25.

Characterization of a new regulatory CD4+ T cell subset in primary Sjögren's syndrome.

Alunno A, Petrillo MG, Nocentini G, Bistoni O, Bartoloni E, Caterbi S, Bianchini R, Baldini C, Nicoletti I, Riccardi C, Gerli R.

Rheumatology (Oxford). 2013 Aug;52(8):1387-96. doi: 10.1093/rheumatology/ket179. Epub 2013 May 14.

PMID:
23674818
26.

Expansion of CD4+CD25-GITR+ regulatory T-cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity.

Alunno A, Nocentini G, Bistoni O, Petrillo MG, Bartoloni Bocci E, Ronchetti S, Lo Vaglio E, Riccardi C, Gerli R.

Reumatismo. 2012 Dec 11;64(5):293-8. doi: 10.4081/reumatismo.2012.293.

PMID:
23256104
27.

The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling.

McKelvey L, Gutierrez H, Nocentini G, Crampton SJ, Davies AM, Riccardi CR, O'keeffe GW.

Biol Open. 2012 Oct 15;1(10):1016-23. doi: 10.1242/bio.20121024. Epub 2012 Aug 20.

28.

Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways.

Ayroldi E, Cannarile L, Migliorati G, Nocentini G, Delfino DV, Riccardi C.

FASEB J. 2012 Dec;26(12):4805-20. doi: 10.1096/fj.12-216382. Epub 2012 Sep 5. Review.

PMID:
22954589
29.

Balance between regulatory T and Th17 cells in systemic lupus erythematosus: the old and the new.

Alunno A, Bartoloni E, Bistoni O, Nocentini G, Ronchetti S, Caterbi S, Valentini V, Riccardi C, Gerli R.

Clin Dev Immunol. 2012;2012:823085. doi: 10.1155/2012/823085. Epub 2012 Jun 14. Review.

30.

CD8+ T cells: GITR matters.

Ronchetti S, Nocentini G, Petrillo MG, Riccardi C.

ScientificWorldJournal. 2012;2012:308265. doi: 10.1100/2012/308265. Epub 2012 Apr 30. Review.

31.

Pharmacological modulation of GITRL/GITR system: therapeutic perspectives.

Nocentini G, Ronchetti S, Petrillo MG, Riccardi C.

Br J Pharmacol. 2012 Apr;165(7):2089-99. doi: 10.1111/j.1476-5381.2011.01753.x. Review.

32.

Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells.

Ceccarelli V, Racanicchi S, Martelli MP, Nocentini G, Fettucciari K, Riccardi C, Marconi P, Di Nardo P, Grignani F, Binaglia L, Vecchini A.

J Biol Chem. 2011 Aug 5;286(31):27092-102. doi: 10.1074/jbc.M111.253609. Epub 2011 Jun 9.

33.

GITR gene deletion and GITR-FC soluble protein administration inhibit multiple organ failure induced by zymosan.

Galuppo M, Nocentini G, Mazzon E, Ronchetti S, Esposito E, Riccardi L, Di Paola R, Bruscoli S, Riccardi C, Cuzzocrea S.

Shock. 2011 Sep;36(3):263-71. doi: 10.1097/SHK.0b013e3182262c48.

PMID:
21654556
34.

CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-cell population with regulatory activity.

Bianchini R, Bistoni O, Alunno A, Petrillo MG, Ronchetti S, Sportoletti P, Bocci EB, Nocentini G, Gerli R, Riccardi C.

Eur J Immunol. 2011 Aug;41(8):2269-78. doi: 10.1002/eji.201040943. Epub 2011 Jul 4.

35.

The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice.

Galuppo M, Nocentini G, Mazzon E, Ronchetti S, Esposito E, Riccardi L, Sportoletti P, Di Paola R, Bruscoli S, Riccardi C, Cuzzocrea S.

Br J Pharmacol. 2011 Mar;162(5):1186-201. doi: 10.1111/j.1476-5381.2010.01123.x.

36.

[Glucocorticoid induced TNFR-related protein (GITR) as marker of human regulatory T cells: expansion of the GITR(+)CD25⁻ cell subset in patients with systemic lupus erythematosus].

Alunno A, Nocentini G, Bistoni O, Bianchini R, Bartoloni Bocci E, Riccardi C, Gerli R.

Reumatismo. 2010 Jul-Sep;62(3):195-201. Italian.

37.

Effect of dietary saturated fatty acids on HNF-4α DNA binding activity and ApoCIII mRNA in sedentary rat liver.

Ceccarelli V, Nocentini G, Riccardi C, Ayroldi E, Di Nardo P, Roberti R, Binaglia L, Vecchini A.

Mol Cell Biochem. 2011 Jan;347(1-2):29-39. doi: 10.1007/s11010-010-0609-0. Epub 2010 Oct 12.

PMID:
20938723
38.

Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity.

Ronchetti S, Nocentini G, Petrillo MG, Bianchini R, Sportoletti P, Bastianelli A, Ayroldi EM, Riccardi C.

Immunol Lett. 2011 Mar 30;135(1-2):24-33. doi: 10.1016/j.imlet.2010.09.008. Epub 2010 Sep 29.

PMID:
20883723
39.

Role of regulatory T cells in rheumatoid arthritis: facts and hypothesis.

Alunno A, Bartoloni E, Nocentini G, Bistoni O, Ronchetti S, Petrillo MG, Riccardi C, Gerli R.

Auto Immun Highlights. 2010 Jul 10;1(1):45-51. doi: 10.1007/s13317-010-0008-2. eCollection 2010 May. Review.

40.

Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice.

Cantarella G, Di Benedetto G, Scollo M, Paterniti I, Cuzzocrea S, Bosco P, Nocentini G, Riccardi C, Bernardini R.

Neuropsychopharmacology. 2010 May;35(6):1302-14. doi: 10.1038/npp.2009.234. Epub 2010 Jan 27.

41.

GITR: a modulator of immune response and inflammation.

Nocentini G, Riccardi C.

Adv Exp Med Biol. 2009;647:156-73. doi: 10.1007/978-0-387-89520-8_11. Review.

PMID:
19760073
42.

The GITRL-GITR system alters TLR-4 expression on DC during fungal infection.

Vecchiarelli A, Pericolini E, Gabrielli E, Agostini M, Bistoni F, Nocentini G, Cenci E, Riccardi C.

Cell Immunol. 2009;257(1-2):13-22. doi: 10.1016/j.cellimm.2009.02.001. Epub 2009 Mar 9.

PMID:
19272591
43.

Identification of regulatory T cells in systemic lupus erythematosus.

Gerli R, Nocentini G, Alunno A, Bocci EB, Bianchini R, Bistoni O, Riccardi C.

Autoimmun Rev. 2009 Mar;8(5):426-30. doi: 10.1016/j.autrev.2009.01.004. Epub 2009 Feb 8. Review.

PMID:
19185065
44.

Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity.

Tentori L, Muzi A, Dorio AS, Bultrini S, Mazzon E, Lacal PM, Shah GM, Zhang J, Navarra P, Nocentini G, Cuzzocrea S, Graziani G.

Eur J Cancer. 2008 Jun;44(9):1302-14. doi: 10.1016/j.ejca.2008.03.019. Epub 2008 Apr 24.

PMID:
18440222
45.

Glucocorticoid-induced tumor necrosis factor receptor-related (GITR)-Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury.

Nocentini G, Cuzzocrea S, Genovese T, Bianchini R, Mazzon E, Ronchetti S, Esposito E, Rosanna DP, Bramanti P, Riccardi C.

Mol Pharmacol. 2008 Jun;73(6):1610-21. doi: 10.1124/mol.107.044354. Epub 2008 Mar 5.

PMID:
18322000
46.

Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids.

Cuzzocrea S, Bruscoli S, Mazzon E, Crisafulli C, Donato V, Di Paola R, Velardi E, Esposito E, Nocentini G, Riccardi C.

Mol Pharmacol. 2008 Feb;73(2):323-37. Epub 2007 Nov 5.

PMID:
17984196
47.

Glucocorticoid-induced TNFR-related protein lowers the threshold of CD28 costimulation in CD8+ T cells.

Ronchetti S, Nocentini G, Bianchini R, Krausz LT, Migliorati G, Riccardi C.

J Immunol. 2007 Nov 1;179(9):5916-26.

48.

Modulation of acute and chronic inflammation of the lung by GITR and its ligand.

Nocentini G, Cuzzocrea S, Bianchini R, Mazzon E, Riccardi C.

Ann N Y Acad Sci. 2007 Jun;1107:380-91. Review.

PMID:
17804566
49.

GITR-GITRL system, a novel player in shock and inflammation.

Krausz LT, Bianchini R, Ronchetti S, Fettucciari K, Nocentini G, Riccardi C.

ScientificWorldJournal. 2007 May 1;7:533-66. Review.

50.

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.

Grohmann U, Volpi C, Fallarino F, Bozza S, Bianchi R, Vacca C, Orabona C, Belladonna ML, Ayroldi E, Nocentini G, Boon L, Bistoni F, Fioretti MC, Romani L, Riccardi C, Puccetti P.

Nat Med. 2007 May;13(5):579-86. Epub 2007 Apr 8.

PMID:
17417651

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