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Items: 12

1.

Clonal tracking in gene therapy patients reveals a diversity of human hematopoietic differentiation programs.

Six E, Guilloux A, Denis A, Lecoules A, Magnani A, Vilette R, Male F, Cagnard N, Delville M, Magrin E, Caccavelli L, Roudaut C, Plantier C, Sobrino S, Gregg J, Nobles CL, Everett JK, Hacein-Bey-Abina S, Galy A, Fischer A, Thrasher AJ, André I, Cavazzana M, Bushman F.

Blood. 2020 Feb 7. pii: blood.2019002350. doi: 10.1182/blood.2019002350. [Epub ahead of print]

PMID:
32040546
2.

CRISPR-engineered T cells in patients with refractory cancer.

Stadtmauer EA, Fraietta JA, Davis MM, Cohen AD, Weber KL, Lancaster E, Mangan PA, Kulikovskaya I, Gupta M, Chen F, Tian L, Gonzalez VE, Xu J, Jung IY, Melenhorst JJ, Plesa G, Shea J, Matlawski T, Cervini A, Gaymon AL, Desjardins S, Lamontagne A, Salas-Mckee J, Fesnak A, Siegel DL, Levine BL, Jadlowsky JK, Young RM, Chew A, Hwang WT, Hexner EO, Carreno BM, Nobles CL, Bushman FD, Parker KR, Qi Y, Satpathy AT, Chang HY, Zhao Y, Lacey SF, June CH.

Science. 2020 Feb 6. pii: eaba7365. doi: 10.1126/science.aba7365. [Epub ahead of print]

PMID:
32029687
3.

CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration.

Nobles CL, Sherrill-Mix S, Everett JK, Reddy S, Fraietta JA, Porter DL, Frey N, Gill SI, Grupp SA, Maude SL, Siegel DL, Levine BL, June CH, Lacey SF, Melenhorst JJ, Bushman FD.

J Clin Invest. 2020 Feb 3;130(2):673-685. doi: 10.1172/JCI130144.

4.

iGUIDE: an improved pipeline for analyzing CRISPR cleavage specificity.

Nobles CL, Reddy S, Salas-McKee J, Liu X, June CH, Melenhorst JJ, Davis MM, Zhao Y, Bushman FD.

Genome Biol. 2019 Jan 17;20(1):14. doi: 10.1186/s13059-019-1625-3.

5.

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.

Ruella M, Xu J, Barrett DM, Fraietta JA, Reich TJ, Ambrose DE, Klichinsky M, Shestova O, Patel PR, Kulikovskaya I, Nazimuddin F, Bhoj VG, Orlando EJ, Fry TJ, Bitter H, Maude SL, Levine BL, Nobles CL, Bushman FD, Young RM, Scholler J, Gill SI, June CH, Grupp SA, Lacey SF, Melenhorst JJ.

Nat Med. 2018 Oct;24(10):1499-1503. doi: 10.1038/s41591-018-0201-9. Epub 2018 Oct 1.

6.

Long-term remission despite clonal expansion of replication-competent HIV-1 isolates.

Veenhuis RT, Kwaa AK, Garliss CC, Latanich R, Salgado M, Pohlmeyer CW, Nobles CL, Gregg J, Scully EP, Bailey JR, Bushman FD, Blankson JN.

JCI Insight. 2018 Sep 20;3(18). pii: 122795. doi: 10.1172/jci.insight.122795. eCollection 2018 Sep 20.

7.

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells.

Fraietta JA, Nobles CL, Sammons MA, Lundh S, Carty SA, Reich TJ, Cogdill AP, Morrissette JJD, DeNizio JE, Reddy S, Hwang Y, Gohil M, Kulikovskaya I, Nazimuddin F, Gupta M, Chen F, Everett JK, Alexander KA, Lin-Shiao E, Gee MH, Liu X, Young RM, Ambrose D, Wang Y, Xu J, Jordan MS, Marcucci KT, Levine BL, Garcia KC, Zhao Y, Kalos M, Porter DL, Kohli RM, Lacey SF, Berger SL, Bushman FD, June CH, Melenhorst JJ.

Nature. 2018 Jun;558(7709):307-312. doi: 10.1038/s41586-018-0178-z. Epub 2018 May 30.

8.

A dual component heme biosensor that integrates heme transport and synthesis in bacteria.

Nobles CL, Clark JR, Green SI, Maresso AW.

J Microbiol Methods. 2015 Nov;118:7-17. doi: 10.1016/j.mimet.2015.07.011. Epub 2015 Aug 4.

9.

Combining random gene fission and rational gene fusion to discover near-infrared fluorescent protein fragments that report on protein-protein interactions.

Pandey N, Nobles CL, Zechiedrich L, Maresso AW, Silberg JJ.

ACS Synth Biol. 2015 May 15;4(5):615-24. doi: 10.1021/sb5002938. Epub 2014 Oct 14.

10.

A product of heme catabolism modulates bacterial function and survival.

Nobles CL, Green SI, Maresso AW.

PLoS Pathog. 2013;9(7):e1003507. doi: 10.1371/journal.ppat.1003507. Epub 2013 Jul 25.

11.

Hal Is a Bacillus anthracis heme acquisition protein.

Balderas MA, Nobles CL, Honsa ES, Alicki ER, Maresso AW.

J Bacteriol. 2012 Oct;194(20):5513-21. Epub 2012 Aug 3.

12.

The theft of host heme by Gram-positive pathogenic bacteria.

Nobles CL, Maresso AW.

Metallomics. 2011 Aug;3(8):788-96. doi: 10.1039/c1mt00047k. Epub 2011 Jul 4. Review.

PMID:
21725569

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