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Items: 49


A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans.

Brimacombe CA, Burke JE, Parsa JY, Catania S, O'Meara TR, Witchley JN, Burrack LS, Madhani HD, Noble SM.

PLoS Biol. 2019 Jun 21;17(6):e3000331. doi: 10.1371/journal.pbio.3000331. eCollection 2019 Jun.


The Functional Brain Organization of an Individual Allows Prediction of Measures of Social Abilities Transdiagnostically in Autism and Attention-Deficit/Hyperactivity Disorder.

Lake EMR, Finn ES, Noble SM, Vanderwal T, Shen X, Rosenberg MD, Spann MN, Chun MM, Scheinost D, Constable RT.

Biol Psychiatry. 2019 Aug 15;86(4):315-326. doi: 10.1016/j.biopsych.2019.02.019. Epub 2019 Mar 7.


Candida albicans Morphogenesis Programs Control the Balance between Gut Commensalism and Invasive Infection.

Witchley JN, Penumetcha P, Abon NV, Woolford CA, Mitchell AP, Noble SM.

Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6. doi: 10.1016/j.chom.2019.02.008.


High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.

O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, Cowen LE.

MBio. 2018 Aug 21;9(4). pii: e01581-18. doi: 10.1128/mBio.01581-18.


Core Items for a Standardized Resource Use Measure: Expert Delphi Consensus Survey.

Thorn JC, Brookes ST, Ridyard C, Riley R, Hughes DA, Wordsworth S, Noble SM, Thornton G, Hollingworth W.

Value Health. 2018 Jun;21(6):640-649. doi: 10.1016/j.jval.2017.06.011. Epub 2017 Sep 1.


Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.

Tian C, Hromatka BS, Kiefer AK, Eriksson N, Noble SM, Tung JY, Hinds DA.

Nat Commun. 2017 Sep 19;8(1):599. doi: 10.1038/s41467-017-00257-5.


Discovery of novel inhibitors of multidrug-resistant Acinetobacter baumannii.

Soojhawon I, Pattabiraman N, Tsang A, Roth AL, Kang E, Noble SM.

Bioorg Med Chem. 2017 Oct 15;25(20):5477-5482. doi: 10.1016/j.bmc.2017.08.014. Epub 2017 Aug 9.


Long-term effects of the Active for Life Year 5 (AFLY5) school-based cluster-randomised controlled trial.

Anderson EL, Howe LD, Kipping RR, Campbell R, Jago R, Noble SM, Wells S, Chittleborough C, Peters TJ, Lawlor DA.

BMJ Open. 2016 Nov 24;6(11):e010957. doi: 10.1136/bmjopen-2015-010957.


Candida albicans cell-type switching and functional plasticity in the mammalian host.

Noble SM, Gianetti BA, Witchley JN.

Nat Rev Microbiol. 2017 Feb;15(2):96-108. doi: 10.1038/nrmicro.2016.157. Epub 2016 Nov 21. Review.


Active for Life Year 5: a cluster randomised controlled trial of a primary school-based intervention to increase levels of physical activity, decrease sedentary behaviour and improve diet.

Lawlor DA, Kipping RR, Anderson EL, Howe LD, Chittleborough CR, Moure-Fernandez A, Noble SM, Rawlins E, Wells SL, Peters TJ, Jago R, Campell R.

Southampton (UK): NIHR Journals Library; 2016 Jun.


Comparing open and minimally invasive surgical procedures for oesophagectomy in the treatment of cancer: the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) feasibility study and pilot trial.

Metcalfe C, Avery K, Berrisford R, Barham P, Noble SM, Fernandez AM, Hanna G, Goldin R, Elliott J, Wheatley T, Sanders G, Hollowood A, Falk S, Titcomb D, Streets C, Donovan JL, Blazeby JM.

Health Technol Assess. 2016 Jun;20(48):1-68. doi: 10.3310/hta20480.


The Impact of the Teen Outreach Program on Sexual Intentions and Behaviors.

Walsh-Buhi ER, Marhefka SL, Wang W, Debate R, Perrin K, Singleton A, Noble CA, Rahman S, Maness SB, Mahony H, Ziemba R, Malmi M, Marwah E, Hall K, Turner D, Blunt-Vinti H, Noble SM, Daley EM.

J Adolesc Health. 2016 Sep;59(3):283-290. doi: 10.1016/j.jadohealth.2016.05.007. Epub 2016 Jun 16. Erratum in: J Adolesc Health. 2016 Nov;59(5):607.


Validating the use of Hospital Episode Statistics data and comparison of costing methodologies for economic evaluation: an end-of-life case study from the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).

Thorn JC, Turner EL, Hounsome L, Walsh E, Down L, Verne J, Donovan JL, Neal DE, Hamdy FC, Martin RM, Noble SM; CAP trial group.

BMJ Open. 2016 Apr 29;6(4):e011063. doi: 10.1136/bmjopen-2016-011063.


Validation of the Hospital Episode Statistics Outpatient Dataset in England.

Thorn JC, Turner E, Hounsome L, Walsh E, Donovan JL, Verne J, Neal DE, Hamdy FC, Martin RM, Noble SM.

Pharmacoeconomics. 2016 Feb;34(2):161-8. doi: 10.1007/s40273-015-0326-3.


Methodological developments in randomized controlled trial-based economic evaluations.

Thorn JC, Noble SM, Hollingworth W.

Expert Rev Pharmacoecon Outcomes Res. 2014 Dec;14(6):843-56. doi: 10.1586/14737167.2014.953934. Epub 2014 Sep 2. Review.


Effect of intervention aimed at increasing physical activity, reducing sedentary behaviour, and increasing fruit and vegetable consumption in children: active for Life Year 5 (AFLY5) school based cluster randomised controlled trial.

Kipping RR, Howe LD, Jago R, Campbell R, Wells S, Chittleborough CR, Mytton J, Noble SM, Peters TJ, Lawlor DA.

BMJ. 2014 May 27;348:g3256. doi: 10.1136/bmj.g3256.


Impact of a transposon insertion in phzF2 on the specialized metabolite production and interkingdom interactions of Pseudomonas aeruginosa.

Phelan VV, Moree WJ, Aguilar J, Cornett DS, Koumoutsi A, Noble SM, Pogliano K, Guerrero CA, Dorrestein PC.

J Bacteriol. 2014 May;196(9):1683-93. doi: 10.1128/JB.01258-13. Epub 2014 Feb 14.


Candida albicans specializations for iron homeostasis: from commensalism to virulence.

Noble SM.

Curr Opin Microbiol. 2013 Dec;16(6):708-15. doi: 10.1016/j.mib.2013.09.006. Epub 2013 Oct 10.


Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism.

Pande K, Chen C, Noble SM.

Nat Genet. 2013 Sep;45(9):1088-91. doi: 10.1038/ng.2710. Epub 2013 Jul 28.


The Active for Life Year 5 (AFLY5) school-based cluster randomised controlled trial protocol: detailed statistical analysis plan.

Lawlor DA, Peters TJ, Howe LD, Noble SM, Kipping RR, Jago R.

Trials. 2013 Jul 24;14:234. doi: 10.1186/1745-6215-14-234.


Resource-use measurement based on patient recall: issues and challenges for economic evaluation.

Thorn JC, Coast J, Cohen D, Hollingworth W, Knapp M, Noble SM, Ridyard C, Wordsworth S, Hughes D.

Appl Health Econ Health Policy. 2013 Jun;11(3):155-61. doi: 10.1007/s40258-013-0022-4.


Timely and complete publication of economic evaluations alongside randomized controlled trials.

Thorn JC, Noble SM, Hollingworth W.

Pharmacoeconomics. 2013 Jan;31(1):77-85. doi: 10.1007/s40273-012-0004-7.


Post-transcriptional regulation of the Sef1 transcription factor controls the virulence of Candida albicans in its mammalian host.

Chen C, Noble SM.

PLoS Pathog. 2012;8(11):e1002956. doi: 10.1371/journal.ppat.1002956. Epub 2012 Nov 1.


Missing data in trial-based cost-effectiveness analysis: the current state of play.

Noble SM, Hollingworth W, Tilling K.

Health Econ. 2012 Feb;21(2):187-200. doi: 10.1002/hec.1693. Epub 2010 Dec 15.


An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis.

Chen C, Pande K, French SD, Tuch BB, Noble SM.

Cell Host Microbe. 2011 Aug 18;10(2):118-35. doi: 10.1016/j.chom.2011.07.005.


The Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial: study protocol for a randomized controlled trial.

Lawlor DA, Jago R, Noble SM, Chittleborough CR, Campbell R, Mytton J, Howe LD, Peters TJ, Kipping RR.

Trials. 2011 Jul 24;12:181. doi: 10.1186/1745-6215-12-181.


Genetics and molecular biology in Candida albicans.

Hernday AD, Noble SM, Mitrovich QM, Johnson AD.

Methods Enzymol. 2010;470:737-58. doi: 10.1016/S0076-6879(10)70031-8. Epub 2010 Mar 1.


Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity.

Noble SM, French S, Kohn LA, Chen V, Johnson AD.

Nat Genet. 2010 Jul;42(7):590-8. doi: 10.1038/ng.605. Epub 2010 Jun 13.


A phenotypic profile of the Candida albicans regulatory network.

Homann OR, Dea J, Noble SM, Johnson AD.

PLoS Genet. 2009 Dec;5(12):e1000783. doi: 10.1371/journal.pgen.1000783. Epub 2009 Dec 24.


An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth.

Elson SL, Noble SM, Solis NV, Filler SG, Johnson AD.

PLoS Genet. 2009 Sep;5(9):e1000664. doi: 10.1371/journal.pgen.1000664. Epub 2009 Sep 25. Erratum in: PLoS Genet. 2009 Oct;5(10). doi: 10.1371/annotation/17eb3a67-8f49-454b-acbf-5ff2872c27ff.


Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans.

Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, Noble SM.

Cell. 2008 Oct 3;135(1):174-88. doi: 10.1016/j.cell.2008.07.046.


Genetics of Candida albicans, a diploid human fungal pathogen.

Noble SM, Johnson AD.

Annu Rev Genet. 2007;41:193-211. Review.


Identification of catalytic cysteine, histidine, and lysine residues in Escherichia coli homoserine transsuccinylase.

Ziegler K, Noble SM, Mutumanje E, Bishop B, Huddler DP, Born TL.

Biochemistry. 2007 Mar 13;46(10):2674-83. Epub 2007 Feb 16.


Human PXR forms a tryptophan zipper-mediated homodimer.

Noble SM, Carnahan VE, Moore LB, Luntz T, Wang H, Ittoop OR, Stimmel JB, Davis-Searles PR, Watkins RE, Wisely GB, LeCluyse E, Tripathy A, McDonnell DP, Redinbo MR.

Biochemistry. 2006 Jul 18;45(28):8579-89.


Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence.

Hromatka BS, Noble SM, Johnson AD.

Mol Biol Cell. 2005 Oct;16(10):4814-26. Epub 2005 Jul 19.


A cost-consequences analysis of minor injuries telemedicine.

Noble SM, Coast J, Benger JR.

J Telemed Telecare. 2005;11(1):15-9.


The safety and effectiveness of minor injuries telemedicine.

Benger JR, Noble SM, Coast J, Kendall JM.

Emerg Med J. 2004 Jul;21(4):438-45.


2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin.

Watkins RE, Maglich JM, Moore LB, Wisely GB, Noble SM, Davis-Searles PR, Lambert MH, Kliewer SA, Redinbo MR.

Biochemistry. 2003 Feb 18;42(6):1430-8.


Effects of molecular crowding by saccharides on alpha-chymotrypsin dimerization.

Patel CN, Noble SM, Weatherly GT, Tripathy A, Winzor DJ, Pielak GJ.

Protein Sci. 2002 May;11(5):997-1003.


Structural insights into the promiscuity and function of the human pregnane X receptor.

Watkins RE, Noble SM, Redinbo MR.

Curr Opin Drug Discov Devel. 2002 Jan;5(1):150-8. Review.


CfT-I: an LTR-retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato.

McHale MT, Roberts IN, Noble SM, Beaumont C, Whitehead MP, Seth D, Oliver RP.

Mol Gen Genet. 1992 Jun;233(3):337-47.


The gamma delta resolvase induces an unusual DNA structure at the recombinational crossover point.

Hatfull GF, Noble SM, Grindley ND.

Cell. 1987 Apr 10;49(1):103-10.


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