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Supersonic shear-wave elastography and APRI for the detection and staging of liver disease in pediatric cystic fibrosis.

Calvopina DA, Noble C, Weis A, Hartel GF, Ramm LE, Balouch F, Fernandez-Rojo MA, Coleman MA, Lewindon PJ, Ramm GA.

J Cyst Fibros. 2019 Jul 11. pii: S1569-1993(19)30820-3. doi: 10.1016/j.jcf.2019.06.017. [Epub ahead of print]


IBD prevalence in Lothian, Scotland, derived by capture-recapture methodology.

Jones GR, Lyons M, Plevris N, Jenkinson PW, Bisset C, Burgess C, Din S, Fulforth J, Henderson P, Ho GT, Kirkwood K, Noble C, Shand AG, Wilson DC, Arnott ID, Lees CW.

Gut. 2019 Jul 11. pii: gutjnl-2019-318936. doi: 10.1136/gutjnl-2019-318936. [Epub ahead of print]


Effect of cyclic deformation on xenogeneic heart valve biomaterials.

Dalgliesh AJ, Parvizi M, Noble C, Griffiths LG.

PLoS One. 2019 Jun 13;14(6):e0214656. doi: 10.1371/journal.pone.0214656. eCollection 2019.


Comprehensive investigation on synthetic cannabinoids: metabolic behaviour and potency testing, using 5F-APP-PICA and AMB-FUBINACA as model compounds.

Fabregat-Safont D, Mardal M, Noble C, Cannaert A, Stove CP, Sancho JV, Linnet K, Hernández F, Ibáñez M.

Drug Test Anal. 2019 Jun 13. doi: 10.1002/dta.2659. [Epub ahead of print]


Ocular Adverse Events following Use of Immune Checkpoint Inhibitors for Metastatic Malignancies.

Noble CW, Gangaputra SS, Thompson IA, Yuan A, Apolo AB, Lee JM, Papaliodis GN, Kodati S, Bishop R, Magone MT, Sobrin L, Sen HN.

Ocul Immunol Inflamm. 2019 Apr 23:1-6. doi: 10.1080/09273948.2019.1583347. [Epub ahead of print]


Pharmacy student professional identity formation: a scoping review.

Noble C, McKauge L, Clavarino A.

Integr Pharm Res Pract. 2019 Mar 27;8:15-34. doi: 10.2147/IPRP.S162799. eCollection 2019. Review.


Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models.

Kamoun WS, Kirpotin DB, Huang ZR, Tipparaju SK, Noble CO, Hayes ME, Luus L, Koshkaryev A, Kim J, Olivier K, Kornaga T, Oyama S, Askoxylakis V, Pien C, Kuesters G, Dumont N, Lugovskoy AA, Schihl SA, Wilton JH, Geddie ML, Suchy J, Grabow S, Kohli N, Reynolds CP, Blaydes R, Zhou Y, Sawyer AJ, Marks JD, Drummond DC.

Nat Biomed Eng. 2019 Apr;3(4):264-280. doi: 10.1038/s41551-019-0385-4. Epub 2019 Apr 5.


Daisy-chain gene drives for the alteration of local populations.

Noble C, Min J, Olejarz J, Buchthal J, Chavez A, Smidler AL, DeBenedictis EA, Church GM, Nowak MA, Esvelt KM.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8275-8282. doi: 10.1073/pnas.1716358116. Epub 2019 Apr 2.


Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis.

Lewindon PJ, Puertolas-Lopez MV, Ramm LE, Noble C, Pereira TN, Wixey JA, Hartel GF, Calvopina DA, Leung DH, Ramm GA.

Clin Gastroenterol Hepatol. 2019 Mar 15. pii: S1542-3565(19)30279-4. doi: 10.1016/j.cgh.2019.03.015. [Epub ahead of print]


In Silico Performance of a Recellularized Tissue Engineered Transcatheter Aortic Valve.

Noble C, Choe J, Uthamaraj S, Deherrera M, Lerman A, Young M.

J Biomech Eng. 2019 Mar 15. doi: 10.1115/1.4043209. [Epub ahead of print]


Evaluation of a multispecies probiotic as a supportive treatment for diarrhea in dairy calves: A randomized clinical trial.

Renaud DL, Kelton DF, Weese JS, Noble C, Duffield TF.

J Dairy Sci. 2019 May;102(5):4498-4505. doi: 10.3168/jds.2018-15793. Epub 2019 Mar 7.


In Vivo Response of Acellular Porcine Pericardial for Tissue Engineered Transcatheter Aortic Valves.

Khorramirouz R, Go JL, Noble C, Morse D, Lerman A, Young MD.

Sci Rep. 2019 Jan 31;9(1):1094. doi: 10.1038/s41598-018-37550-2.


Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK.

Hey F, Andreadi C, Noble C, Patel B, Jin H, Kamata T, Straatman K, Luo J, Balmanno K, Jones DTW, Collins VP, Cook SJ, Caunt CJ, Pritchard C.

Heliyon. 2018 Dec 20;4(12):e01065. doi: 10.1016/j.heliyon.2018.e01065. eCollection 2018 Dec.


Case of steroid-resistant Crohn's-associated bronchiolitis in the setting of quiescent gastrointestinal disease treated with infliximab.

Chuah CS, Noble C, Leitch A.

BMJ Case Rep. 2018 Nov 28;11(1). pii: e226934. doi: 10.1136/bcr-2018-226934.


Experimental Metabolic Syndrome Model Associated with Mechanical and Structural Degenerative Changes of the Aortic Valve.

Go JL, Prem K, Al-Hijji MA, Qin Q, Noble C, Young MD, Lerman LO, Lerman A.

Sci Rep. 2018 Dec 13;8(1):17835. doi: 10.1038/s41598-018-36388-y.


Implementation of CT-P13 via a Managed Switch Programme in Crohn's Disease: 12-Month Real-World Outcomes.

Plevris N, Jones GR, Jenkinson PW, Lyons M, Chuah CS, Merchant LM, Pattenden RJ, Watson EF, Ho GT, Noble CL, Din S, Shand AG, Arnott ID, Lees CW.

Dig Dis Sci. 2019 Jun;64(6):1660-1667. doi: 10.1007/s10620-018-5406-8. Epub 2018 Dec 7.


A simple method of incorporating the effect of the Uniform Stress Hypothesis in arterial wall stress computations.

Joldes GR, Noble C, Polzer S, Taylor ZA, Wittek A, Miller K.

Acta Bioeng Biomech. 2018;20(4):59-67.


Development of a flow-through USP 4 apparatus drug release assay for the evaluation of amphotericin B liposome.

Tang J, Srinivasan S, Yuan W, Ming R, Liu Y, Dai Z, Noble CO, Hayes ME, Zheng N, Jiang W, Szoka FC, Schwendeman A.

Eur J Pharm Biopharm. 2019 Jan;134:107-116. doi: 10.1016/j.ejpb.2018.11.010. Epub 2018 Nov 24.


A New Mixed-Valence Mn(II)Mn(III) Compound With Catalase and Superoxide Dismutase Activities.

Costa RO, Ferreira SS, Pereira CA, Harmer JR, Noble CJ, Schenk G, Franco RWA, Resende JALC, Comba P, Roberts AE, Fernandes C, Horn A Jr.

Front Chem. 2018 Nov 5;6:491. doi: 10.3389/fchem.2018.00491. eCollection 2018.


Higher Adalimumab Drug Levels During Maintenance Therapy for Crohn's Disease Are Associated With Biologic Remission.

Plevris N, Lyons M, Jenkinson PW, Chuah CS, Merchant LM, Pattenden RJ, Watson EF, Ho GT, Noble CL, Shand AG, Din S, Arnott ID, Jones GR, Lees CW.

Inflamm Bowel Dis. 2019 May 4;25(6):1036-1043. doi: 10.1093/ibd/izy320.


Supporting Resident Research Learning in the Workplace: A Rapid Realist Review.

Noble C, Billett SR, Phang DTY, Sharma S, Hashem F, Rogers GD.

Acad Med. 2018 Nov;93(11):1732-1740. doi: 10.1097/ACM.0000000000002416.


How can end of life care excellence be normalized in hospitals? Lessons from a qualitative framework study.

Noble C, Grealish L, Teodorczuk A, Shanahan B, Hiremagular B, Morris J, Yardley S.

BMC Palliat Care. 2018 Aug 8;17(1):100. doi: 10.1186/s12904-018-0353-x.


Bromo-dragonfly, a psychoactive benzodifuran, is resistant to hepatic metabolism and potently inhibits monoamine oxidase A.

Noble C, Holm NB, Mardal M, Linnet K.

Toxicol Lett. 2018 Oct 1;295:397-407. doi: 10.1016/j.toxlet.2018.07.018. Epub 2018 Jul 20.


MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis.

Calvopina DA, Chatfield MD, Weis A, Coleman MA, Fernandez-Rojo MA, Noble C, Ramm LE, Leung DH, Lewindon PJ, Ramm GA.

Hepatology. 2018 Dec;68(6):2301-2316. doi: 10.1002/hep.30156. Epub 2018 Nov 15.


Not enough time for research? Use of supported funding to promote allied health research activity.

Wenke R, Weir KA, Noble C, Mahoney J, Mickan S.

J Multidiscip Healthc. 2018 Jun 21;11:269-277. doi: 10.2147/JMDH.S157034. eCollection 2018.


Current CRISPR gene drive systems are likely to be highly invasive in wild populations.

Noble C, Adlam B, Church GM, Esvelt KM, Nowak MA.

Elife. 2018 Jun 19;7. pii: e33423. doi: 10.7554/eLife.33423.


The service/teaching tension: a window into the soul of a hospital.

Teodorczuk A, Ajjawi R, Billett S, Hilder J, Noble C.

Med Educ. 2018 Jun;52(6):678. doi: 10.1111/medu.13527. No abstract available.


Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design.

Lim SP, Noble CG, Nilar S, Shi PY, Yokokawa F.

Adv Exp Med Biol. 2018;1062:187-198. doi: 10.1007/978-981-10-8727-1_14. Review.


The photoreactive free radical in eumelanin.

Mostert AB, Rienecker SB, Noble C, Hanson GR, Meredith P.

Sci Adv. 2018 Mar 28;4(3):eaaq1293. doi: 10.1126/sciadv.aaq1293. eCollection 2018 Mar.


Early Contrast Enhancement: A novel magnetic resonance imaging biomarker of pleural malignancy.

Tsim S, Humphreys CA, Cowell GW, Stobo DB, Noble C, Woodward R, Kelly CA, Alexander L, Foster JE, Dick C, Blyth KG.

Lung Cancer. 2018 Apr;118:48-56. doi: 10.1016/j.lungcan.2018.01.014. Epub 2018 Feb 3.


A novel surgical technique for a rat subcutaneous implantation of a tissue engineered scaffold.

Khorramirouz R, Go JL, Noble C, Jana S, Maxson E, Lerman A, Young MD.

Acta Histochem. 2018 Apr;120(3):282-291. doi: 10.1016/j.acthis.2018.02.010. Epub 2018 Mar 5.


Evolving Practice and Changing Phenotype in Pediatric Autoimmune Liver Disease: Outcomes From an Australian Center.

Singh H, Balouch F, Noble C, Lewindon P.

J Pediatr Gastroenterol Nutr. 2018 Jul;67(1):80-85. doi: 10.1097/MPG.0000000000001927.


Implementing an integrated pathway to care for the dying: is your organisation ready?

Sharpe KK, Noble C, Hiremagular B, Grealish L.

Int J Palliat Nurs. 2018 Feb 2;24(2):70-78. doi: 10.12968/ijpn.2018.24.2.70.


Development, initial validation and reliability testing of a web-based, generic feline health-related quality-of-life instrument.

Noble CE, Wiseman-Orr LM, Scott ME, Nolan AM, Reid J.

J Feline Med Surg. 2019 Feb;21(2):84-94. doi: 10.1177/1098612X18758176. Epub 2018 Feb 21.


Bone Mineral Density of Very Long-term Survivors After Childhood Liver Transplantation.

Ee LC, Noble C, Fawcett J, Cleghorn GJ.

J Pediatr Gastroenterol Nutr. 2018 May;66(5):797-801. doi: 10.1097/MPG.0000000000001881.


Corrigendum: Rapid identification of intact bacterial resistance plasmids via optical mapping of single DNA molecules.

Nyberg LK, Quaderi S, Emilsson G, Karami N, Lagerstedt E, Müller V, Noble C, Hammarberg S, Nilsson AN, Sjöberg F, Fritzsche J, Kristiansson E, Sandegren L, Ambjörnsson T, Westerlund F.

Sci Rep. 2017 Dec 22;7:46911. doi: 10.1038/srep46911.


New therapeutic approaches for brainstem tumors: a comparison of delivery routes using nanoliposomal irinotecan in an animal model.

Louis N, Liu S, He X, Drummond DC, Noble CO, Goldman S, Mueller S, Bankiewicz K, Gupta N, Hashizume R.

J Neurooncol. 2018 Feb;136(3):475-484. doi: 10.1007/s11060-017-2681-8. Epub 2017 Nov 23.


Keeping it simple: the grammatical properties of shared book reading.

Noble CH, Cameron-Faulkner T, Lieven E.

J Child Lang. 2018 May;45(3):753-766. doi: 10.1017/S0305000917000447. Epub 2017 Nov 17.


Metabolism of the synthetic cannabinoid 5F-PY-PICA by human and rat hepatocytes and identification of biliary analytical targets by directional efflux in sandwich-cultured rat hepatocytes using UHPLC-HR-MS/MS.

Mardal M, Annaert P, Noble C, Oorts M, Linnet K.

J Pharm Biomed Anal. 2018 Feb 5;149:296-307. doi: 10.1016/j.jpba.2017.11.027. Epub 2017 Nov 7.


Clinical and genetic heterogeneity in familial steroid-sensitive nephrotic syndrome.

Dorval G, Gribouval O, Martinez-Barquero V, Machuca E, Tête MJ, Baudouin V, Benoit S, Chabchoub I, Champion G, Chauveau D, Chehade H, Chouchane C, Cloarec S, Cochat P, Dahan K, Dantal J, Delmas Y, Deschênes G, Dolhem P, Durand D, Ekinci Z, El Karoui K, Fischbach M, Grunfeld JP, Guigonis V, Hachicha M, Hogan J, Hourmant M, Hummel A, Kamar N, Krummel T, Lacombe D, Llanas B, Mesnard L, Mohsin N, Niaudet P, Nivet H, Parvex P, Pietrement C, de Pontual L, Noble CP, Ribes D, Ronco P, Rondeau E, Sallee M, Tsimaratos M, Ulinski T, Salomon R, Antignac C, Boyer O.

Pediatr Nephrol. 2018 Mar;33(3):473-483. doi: 10.1007/s00467-017-3819-9. Epub 2017 Oct 23.


Design of silk proteins with increased heme binding capacity and fabrication of silk-heme materials.

Rapson TD, Liu JW, Sriskantha A, Musameh M, Dunn CJ, Church JS, Woodhead A, Warden AC, Riley MJ, Harmer JR, Noble CJ, Sutherland TD.

J Inorg Biochem. 2017 Dec;177:219-227. doi: 10.1016/j.jinorgbio.2017.08.031. Epub 2017 Sep 4.


Colonoscopy quality with Entonox®vs intravenous conscious sedation: 18608 colonoscopy retrospective study.

Robertson AR, Kennedy NA, Robertson JA, Church NI, Noble CL.

World J Gastrointest Endosc. 2017 Sep 16;9(9):471-479. doi: 10.4253/wjge.v9.i9.471.


Strategies for research engagement of clinicians in allied health (STRETCH): a mixed methods research protocol.

Mickan S, Wenke R, Weir K, Bialocerkowski A, Noble C.

BMJ Open. 2017 Sep 11;7(9):e014876. doi: 10.1136/bmjopen-2016-014876.


Rural and Urban Differences in Sexual Behaviors Among Adolescents in Florida.

Thompson EL, Mahony H, Noble C, Wang W, Ziemba R, Malmi M, Maness SB, Walsh-Buhi ER, Daley EM.

J Community Health. 2018 Apr;43(2):268-272. doi: 10.1007/s10900-017-0416-6.


Application of a screening method for fentanyl and its analogues using UHPLC-QTOF-MS with data-independent acquisition (DIA) in MSE mode and retrospective analysis of authentic forensic blood samples.

Noble C, Weihe Dalsgaard P, Stybe Johansen S, Linnet K.

Drug Test Anal. 2018 Apr;10(4):651-662. doi: 10.1002/dta.2263. Epub 2017 Oct 27.


Characterization of clinical predictors of naturally occurring NS3/NS4A protease polymorphism in genotype 1 hepatitis C virus mono and HIV co-infected patients.

Lisboa Neto G, Malta FM, Gomes-Gouvêa MS, Noble CF, Romano CM, Rebello Pinho JR, Silva MH, Leite AGB, Piccoli LZ, Carrilho FJ, Mendes-Correa MC.

J Med Virol. 2017 Dec;89(12):2249-2254. doi: 10.1002/jmv.24900. Epub 2017 Aug 11.


Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity.

Naidoo VL, Mann JK, Noble C, Adland E, Carlson JM, Thomas J, Brumme CJ, Thobakgale-Tshabalala CF, Brumme ZL, Brockman MA, Goulder PJR, Ndung'u T.

J Virol. 2017 Aug 10;91(17). pii: e00518-17. doi: 10.1128/JVI.00518-17. Print 2017 Sep 1.


A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.

Manjunatha UH, Vinayak S, Zambriski JA, Chao AT, Sy T, Noble CG, Bonamy GMC, Kondreddi RR, Zou B, Gedeck P, Brooks CF, Herbert GT, Sateriale A, Tandel J, Noh S, Lakshminarayana SB, Lim SH, Goodman LB, Bodenreider C, Feng G, Zhang L, Blasco F, Wagner J, Leong FJ, Striepen B, Diagana TT.

Nature. 2017 Jun 15;546(7658):376-380. doi: 10.1038/nature22337. Epub 2017 May 31.


Evolutionary dynamics of CRISPR gene drives.

Noble C, Olejarz J, Esvelt KM, Church GM, Nowak MA.

Sci Adv. 2017 Apr 5;3(4):e1601964. doi: 10.1126/sciadv.1601964. eCollection 2017 Apr.

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