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Items: 28


Mode and Tempo of Microsatellite Length Change in a Malaria Parasite Mutation Accumulation Experiment.

McDew-White M, Li X, Nkhoma SC, Nair S, Cheeseman I, Anderson TJC.

Genome Biol Evol. 2019 Jul 1;11(7):1971-1985. doi: 10.1093/gbe/evz140.


Intra-host dynamics of co-infecting parasite genotypes in asymptomatic malaria patients.

Nkhoma SC, Banda RL, Khoswe S, Dzoole-Mwale TJ, Ward SA.

Infect Genet Evol. 2018 Nov;65:414-424. doi: 10.1016/j.meegid.2018.08.018. Epub 2018 Aug 23.


Comparison of Two Genotyping Methods for Distinguishing Recrudescence from Reinfection in Antimalarial Drug Efficacy/Effectiveness Trials.

Fulakeza JRM, Banda RL, Lipenga TR, Terlouw DJ, Nkhoma SC, Hodel EM.

Am J Trop Med Hyg. 2018 Jul;99(1):84-86. doi: 10.4269/ajtmh.18-0002. Epub 2018 May 17.


High-Resolution Single-Cell Sequencing of Malaria Parasites.

Trevino SG, Nkhoma SC, Nair S, Daniel BJ, Moncada K, Khoswe S, Banda RL, Nosten F, Cheeseman IH.

Genome Biol Evol. 2017 Dec 1;9(12):3373-3383. doi: 10.1093/gbe/evx256.


Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent.

Taylor AR, Schaffner SF, Cerqueira GC, Nkhoma SC, Anderson TJC, Sriprawat K, Pyae Phyo A, Nosten F, Neafsey DE, Buckee CO.

PLoS Genet. 2017 Oct 27;13(10):e1007065. doi: 10.1371/journal.pgen.1007065. eCollection 2017 Oct.


Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites.

Anderson TJ, Nair S, McDew-White M, Cheeseman IH, Nkhoma S, Bilgic F, McGready R, Ashley E, Pyae Phyo A, White NJ, Nosten F.

Mol Biol Evol. 2017 Jan;34(1):131-144. doi: 10.1093/molbev/msw228. Epub 2016 Oct 20.


Population Structure Shapes Copy Number Variation in Malaria Parasites.

Cheeseman IH, Miller B, Tan JC, Tan A, Nair S, Nkhoma SC, De Donato M, Rodulfo H, Dondorp A, Branch OH, Mesia LR, Newton P, Mayxay M, Amambua-Ngwa A, Conway DJ, Nosten F, Ferdig MT, Anderson TJ.

Mol Biol Evol. 2016 Mar;33(3):603-20. doi: 10.1093/molbev/msv282. Epub 2015 Nov 26.


Defining the in vivo phenotype of artemisinin-resistant falciparum malaria: a modelling approach.

White LJ, Flegg JA, Phyo AP, Wiladpai-ngern JH, Bethell D, Plowe C, Anderson T, Nkhoma S, Nair S, Tripura R, Stepniewska K, Pan-Ngum W, Silamut K, Cooper BS, Lubell Y, Ashley EA, Nguon C, Nosten F, White NJ, Dondorp AM.

PLoS Med. 2015 Apr 28;12(4):e1001823. doi: 10.1371/journal.pmed.1001823. eCollection 2015 Apr.


Subtle changes in Plasmodium falciparum infection complexity following enhanced intervention in Malawi.

Sisya TJ, Kamn'gona RM, Vareta JA, Fulakeza JM, Mukaka MF, Seydel KB, Laufer MK, Taylor TE, Nkhoma SC.

Acta Trop. 2015 Feb;142:108-14. doi: 10.1016/j.actatropica.2014.11.008. Epub 2014 Nov 25.


Single-cell genomics for dissection of complex malaria infections.

Nair S, Nkhoma SC, Serre D, Zimmerman PA, Gorena K, Daniel BJ, Nosten F, Anderson TJ, Cheeseman IH.

Genome Res. 2014 Jun;24(6):1028-38. doi: 10.1101/gr.168286.113. Epub 2014 May 8.


Genetic evaluation of the performance of malaria parasite clearance rate metrics.

Nkhoma SC, Stepniewska K, Nair S, Phyo AP, McGready R, Nosten F, Anderson TJ.

J Infect Dis. 2013 Jul 15;208(2):346-50. doi: 10.1093/infdis/jit165. Epub 2013 Apr 16.


Population genetic correlates of declining transmission in a human pathogen.

Nkhoma SC, Nair S, Al-Saai S, Ashley E, McGready R, Phyo AP, Nosten F, Anderson TJ.

Mol Ecol. 2013 Jan;22(2):273-85. doi: 10.1111/mec.12099. Epub 2012 Nov 2.


A major genome region underlying artemisinin resistance in malaria.

Cheeseman IH, Miller BA, Nair S, Nkhoma S, Tan A, Tan JC, Al Saai S, Phyo AP, Moo CL, Lwin KM, McGready R, Ashley E, Imwong M, Stepniewska K, Yi P, Dondorp AM, Mayxay M, Newton PN, White NJ, Nosten F, Ferdig MT, Anderson TJ.

Science. 2012 Apr 6;336(6077):79-82. doi: 10.1126/science.1215966.


Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study.

Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, McGready R, ler Moo C, Al-Saai S, Dondorp AM, Lwin KM, Singhasivanon P, Day NP, White NJ, Anderson TJ, Nosten F.

Lancet. 2012 May 26;379(9830):1960-6. doi: 10.1016/S0140-6736(12)60484-X. Epub 2012 Apr 5.


Close kinship within multiple-genotype malaria parasite infections.

Nkhoma SC, Nair S, Cheeseman IH, Rohr-Allegrini C, Singlam S, Nosten F, Anderson TJ.

Proc Biol Sci. 2012 Jul 7;279(1738):2589-98. doi: 10.1098/rspb.2012.0113. Epub 2012 Mar 7.


Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication.

Brumlik MJ, Nkhoma S, Kious MJ, Thompson GR 3rd, Patterson TF, Siekierka JJ, Anderson TJ, Curiel TJ.

Exp Parasitol. 2011 Jun;128(2):170-5. doi: 10.1016/j.exppara.2011.02.016. Epub 2011 Feb 19.


How can we identify parasite genes that underlie antimalarial drug resistance?

Anderson T, Nkhoma S, Ecker A, Fidock D.

Pharmacogenomics. 2011 Jan;12(1):59-85. doi: 10.2217/pgs.10.165. Review.


The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children.

Mankhambo LA, Banda DL; IPD Study Group, Jeffers G, White SA, Balmer P, Nkhoma S, Phiri H, Molyneux EM, Hart CA, Molyneux ME, Heyderman RS, Carrol ED.

Crit Care. 2010;14(3):R91. doi: 10.1186/cc9025. Epub 2010 May 21.


Genetic changes during laboratory propagation: copy number At the reticulocyte-binding protein 1 locus of Plasmodium falciparum.

Nair S, Nkhoma S, Nosten F, Mayxay M, French N, Whitworth J, Anderson T.

Mol Biochem Parasitol. 2010 Aug;172(2):145-8. doi: 10.1016/j.molbiopara.2010.03.015. Epub 2010 Apr 2.


High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia.

Anderson TJ, Nair S, Nkhoma S, Williams JT, Imwong M, Yi P, Socheat D, Das D, Chotivanich K, Day NP, White NJ, Dondorp AM.

J Infect Dis. 2010 May 1;201(9):1326-30. doi: 10.1086/651562.


Low level genotypic chloroquine resistance near Malawi's northern border with Tanzania.

Bridges DJ, Molyneux M, Nkhoma S.

Trop Med Int Health. 2009 Sep;14(9):1093-6. doi: 10.1111/j.1365-3156.2009.02340.x. Epub 2009 Jul 14.


Parasites bearing a single copy of the multi-drug resistance gene (pfmdr-1) with wild-type SNPs predominate amongst Plasmodium falciparum isolates from Malawi.

Nkhoma S, Nair S, Mukaka M, Molyneux ME, Ward SA, Anderson TJ.

Acta Trop. 2009 Jul;111(1):78-81. doi: 10.1016/j.actatropica.2009.01.011. Epub 2009 Feb 4.


Effect of transmission setting and mixed species infections on clinical measures of malaria in Malawi.

Bruce MC, Macheso A, Kelly-Hope LA, Nkhoma S, McConnachie A, Molyneux ME.

PLoS One. 2008 Jul 23;3(7):e2775. doi: 10.1371/journal.pone.0002775.


Molecular surveillance for drug-resistant Plasmodiumfalciparum malaria in Malawi.

Nkhoma S, Molyneux M, Ward S.

Acta Trop. 2007 May;102(2):138-42. Epub 2007 Apr 24.


High pneumococcal DNA loads are associated with mortality in Malawian children with invasive pneumococcal disease.

Carrol ED, Guiver M, Nkhoma S, Mankhambo LA, Marsh J, Balmer P, Banda DL, Jeffers G; IPD Study Group, White SA, Molyneux EM, Molyneux ME, Smyth RL, Hart CA.

Pediatr Infect Dis J. 2007 May;26(5):416-22.


Chemokine responses are increased in HIV-infected Malawian children with invasive pneumococcal disease.

Carrol ED, Mankhambo LA, Balmer P, Nkhoma S, Banda DL, Guiver M, Jeffers G, Makwana N, Molyneux EM, Molyneux ME, Smyth RL, Hart CA; Invasive Pneumococcal Disease Study Group.

J Acquir Immune Defic Syndr. 2007 Apr 1;44(4):443-50.

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