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Items: 1 to 50 of 430

1.

Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli.

Patras KA, Ha AD, Rooholfada E, Olson J, Ramachandra Rao SP, Lin AE, Nizet V.

J Innate Immun. 2019 May 3:1-15. doi: 10.1159/000499342. [Epub ahead of print]

2.

An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model.

Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ.

MBio. 2019 Apr 30;10(2). pii: e00693-19. doi: 10.1128/mBio.00693-19.

3.

Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media.

Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Pogliano J, Knight R, Nizet V, Palsson BO, Feist AM.

Sci Data. 2019 Apr 26;6(1):43. doi: 10.1038/s41597-019-0051-4.

4.

Inhibition of Human Neutrophil Extracellular Trap (NET) Production by Propofol and Lipid Emulsion.

Meier A, Chien J, Hobohm L, Patras KA, Nizet V, Corriden R.

Front Pharmacol. 2019 Apr 5;10:323. doi: 10.3389/fphar.2019.00323. eCollection 2019.

5.

Avibactam Sensitizes Carbapenem-Resistant NDM-1-Producing Klebsiella pneumoniae to Innate Immune Clearance.

Ulloa ER, Dillon N, Tsunemoto H, Pogliano J, Sakoulas G, Nizet V.

J Infect Dis. 2019 Mar 29. pii: jiz128. doi: 10.1093/infdis/jiz128. [Epub ahead of print]

PMID:
30923801
6.

Proton-pump inhibitors do not influence clinical outcomes in patients with Staphylococcus aureus bacteremia.

Caffrey AR, Timbrook TT, Ali SR, Nizet V, Sakoulas G.

Therap Adv Gastroenterol. 2019 Mar 21;12:1756284819834273. doi: 10.1177/1756284819834273. eCollection 2019.

7.

The long noncoding RNA ROCKI regulates inflammatory gene expression.

Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, Rana TM.

EMBO J. 2019 Apr 15;38(8). pii: e100041. doi: 10.15252/embj.2018100041. Epub 2019 Mar 27.

8.

Dual actions of group B Streptococcus capsular sialic acid provide resistance to platelet-mediated antimicrobial killing.

Uchiyama S, Sun J, Fukahori K, Ando N, Wu M, Schwarz F, Siddiqui SS, Varki A, Marth JD, Nizet V.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7465-7470. doi: 10.1073/pnas.1815572116. Epub 2019 Mar 25.

PMID:
30910970
9.

Clinical Data on Daptomycin plus Ceftaroline versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia.

Geriak M, Haddad F, Rizvi K, Rose W, Kullar R, LaPlante K, Yu M, Vasina L, Ouellette K, Zervos M, Nizet V, Sakoulas G.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02483-18. doi: 10.1128/AAC.02483-18. Print 2019 May.

10.

Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry.

Bauman KD, Li J, Murata K, Mantovani SM, Dahesh S, Nizet V, Luhavaya H, Moore BS.

Cell Chem Biol. 2019 May 16;26(5):724-736.e7. doi: 10.1016/j.chembiol.2019.02.004. Epub 2019 Mar 7.

PMID:
30853419
11.

Homophilic protein interactions facilitate bacterial aggregation and IgG-dependent complex formation by the Streptococcus canis M protein SCM.

Nerlich A, Lapschies AM, Kohler TP, Cornax I, Eichhorn I, Goldmann O, Krienke P, Bergmann S, Nizet V, Hammerschmidt S, Rohde M, Fulde M.

Virulence. 2019 Dec;10(1):194-206. doi: 10.1080/21505594.2019.1589362.

12.

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells.

Dan JM, Havenar-Daughton C, Kendric K, Al-Kolla R, Kaushik K, Rosales SL, Anderson EL, LaRock CN, Vijayanand P, Seumois G, Layfield D, Cutress RI, Ottensmeier CH, Lindestam Arlehamn CS, Sette A, Nizet V, Bothwell M, Brigger M, Crotty S.

Sci Transl Med. 2019 Feb 6;11(478). pii: eaau3776. doi: 10.1126/scitranslmed.aau3776.

13.

Detection of epidemic scarlet fever group A Streptococcus in Australia.

Walker MJ, Brouwer S, Forde BM, Worthing KA, McIntyre L, Sundac L, Maloney S, Roberts LW, Barnett TC, Richter J, Cork AJ, Irwin AD, You Y, Zhang J, Dougan G, Yuen KY, Nizet V, Beatson SA, Grimwood K, Davies MR.

Clin Infect Dis. 2019 Feb 5. doi: 10.1093/cid/ciz099. [Epub ahead of print]

PMID:
30721938
14.

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.

Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M.

Cell Death Differ. 2019 Mar;26(3):395-408. doi: 10.1038/s41418-018-0261-x. Epub 2019 Jan 8. Review.

PMID:
30622307
15.

Docking simulation and antibiotic discovery targeting the MlaC protein in Gram-negative bacteria.

Huang YM, Munguia J, Miao Y, Nizet V, McCammon JA.

Chem Biol Drug Des. 2019 Apr;93(4):647-652. doi: 10.1111/cbdd.13462. Epub 2019 Feb 19.

PMID:
30570806
16.

Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection.

Escajadillo T, Nizet V.

Toxins (Basel). 2018 Dec 17;10(12). pii: E542. doi: 10.3390/toxins10120542. Review.

17.

Impact of Anesthetics on Human Neutrophil Function.

Meier A, Nizet V.

Anesth Analg. 2019 Mar;128(3):569-574. doi: 10.1213/ANE.0000000000003927.

PMID:
30507837
18.

Erratum for Schooley et al., "Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection".

Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e02221-18. doi: 10.1128/AAC.02221-18. Print 2018 Dec. No abstract available.

19.

The murine vaginal microbiota and its perturbation by the human pathogen group B Streptococcus.

Vrbanac A, Riestra AM, Coady A, Knight R, Nizet V, Patras KA.

BMC Microbiol. 2018 Nov 26;18(1):197. doi: 10.1186/s12866-018-1341-2.

20.

Enhanced topical delivery of non-complexed molecular iodine for Methicillin-resistant Staphylococcus aureus decolonization.

Uchiyama S, Dahesh S, Nizet V, Kessler J.

Int J Pharm. 2019 Jan 10;554:81-86. doi: 10.1016/j.ijpharm.2018.11.004. Epub 2018 Nov 2.

PMID:
30395958
21.

Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages.

Riestra AM, Valderrama JA, Patras KA, Booth SD, Quek XY, Tsai CM, Nizet V.

J Innate Immun. 2019;11(1):86-98. doi: 10.1159/000493585. Epub 2018 Nov 2.

22.

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance.

Kavvas ES, Catoiu E, Mih N, Yurkovich JT, Seif Y, Dillon N, Heckmann D, Anand A, Yang L, Nizet V, Monk JM, Palsson BO.

Nat Commun. 2018 Oct 17;9(1):4306. doi: 10.1038/s41467-018-06634-y.

23.

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects.

van Hensbergen VP, Movert E, de Maat V, Lüchtenborg C, Le Breton Y, Lambeau G, Payré C, Henningham A, Nizet V, van Strijp JAG, Brügger B, Carlsson F, McIver KS, van Sorge NM.

PLoS Pathog. 2018 Oct 15;14(10):e1007348. doi: 10.1371/journal.ppat.1007348. eCollection 2018 Oct.

24.

Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis.

Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD.

Cell Host Microbe. 2018 Oct 10;24(4):500-513.e5. doi: 10.1016/j.chom.2018.09.011.

PMID:
30308156
25.

Tamm-Horsfall Protein Protects the Urinary Tract against Candida albicans.

Coady A, Ramos AR, Olson J, Nizet V, Patras KA.

Infect Immun. 2018 Nov 20;86(12). pii: e00451-18. doi: 10.1128/IAI.00451-18. Print 2018 Dec.

26.

Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells.

Fong JJ, Tsai CM, Saha S, Nizet V, Varki A, Bui JD.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10410-10415. doi: 10.1073/pnas.1804108115. Epub 2018 Sep 25.

27.

Is a Reported Penicillin Allergy Sufficient Grounds to Forgo the Multidimensional Antimicrobial Benefits of β-Lactam Antibiotics?

Sakoulas G, Geriak M, Nizet V.

Clin Infect Dis. 2019 Jan 1;68(1):157-164. doi: 10.1093/cid/ciy557.

PMID:
29986019
28.

Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera.

Alisson-Silva F, Liu JZ, Diaz SL, Deng L, Gareau MG, Marchelletta R, Chen X, Nizet V, Varki N, Barrett KE, Varki A.

PLoS Pathog. 2018 Jun 18;14(6):e1007133. doi: 10.1371/journal.ppat.1007133. eCollection 2018 Jun.

29.

Staphylococcus aureus modulation of innate immune responses through Toll-like (TLR), (NOD)-like (NLR) and C-type lectin (CLR) receptors.

Askarian F, Wagner T, Johannessen M, Nizet V.

FEMS Microbiol Rev. 2018 Sep 1;42(5):656-671. doi: 10.1093/femsre/fuy025.

30.

Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance.

Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V.

J Infect Dis. 2018 Oct 5;218(10):1641-1652. doi: 10.1093/infdis/jiy341.

PMID:
29868829
31.

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP.

Soderholm AT, Barnett TC, Korn O, Rivera-Hernandez T, Seymour LM, Schulz BL, Nizet V, Wells CA, Sweet MJ, Walker MJ.

Front Cell Infect Microbiol. 2018 May 17;8:160. doi: 10.3389/fcimb.2018.00160. eCollection 2018.

32.

Decontaminating surfaces with atomized disinfectants generated by a novel thickness-mode lithium niobate device.

Kumaraswamy M, Collignon S, Do C, Kim J, Nizet V, Friend J.

Appl Microbiol Biotechnol. 2018 Aug;102(15):6459-6467. doi: 10.1007/s00253-018-9088-0. Epub 2018 May 26.

PMID:
29804135
33.
34.

Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit.

Jati S, Kundu S, Chakraborty A, Mahata SK, Nizet V, Sen M.

Front Immunol. 2018 Apr 9;9:679. doi: 10.3389/fimmu.2018.00679. eCollection 2018.

35.

Multifactorial inhibition of lactobacilli against the respiratory tract pathogen Moraxella catarrhalis.

van den Broek MFL, De Boeck I, Claes IJJ, Nizet V, Lebeer S.

Benef Microbes. 2018 Apr 25;9(3):429-439. doi: 10.3920/BM2017.0101. Epub 2018 Apr 10.

PMID:
29633637
37.

Group B Streptococcal Maternal Colonization and Neonatal Disease: Molecular Mechanisms and Preventative Approaches.

Patras KA, Nizet V.

Front Pediatr. 2018 Feb 22;6:27. doi: 10.3389/fped.2018.00027. eCollection 2018. Review.

38.

Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models.

Askarian F, Lapek JD Jr, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M.

Front Microbiol. 2018 Feb 20;9:262. doi: 10.3389/fmicb.2018.00262. eCollection 2018.

39.

SCH79797 improves outcomes in experimental bacterial pneumonia by boosting neutrophil killing and direct antibiotic activity.

Gupta N, Liu R, Shin S, Sinha R, Pogliano J, Pogliano K, Griffin JH, Nizet V, Corriden R.

J Antimicrob Chemother. 2018 Jun 1;73(6):1586-1594. doi: 10.1093/jac/dky033.

40.

Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.

Haripriyan J, Omanakuttan A, Menon ND, Vanuopadath M, Nair SS, Corriden R, Nair BG, Nizet V, Kumar GB.

Sci Rep. 2018 Feb 21;8(1):3437. doi: 10.1038/s41598-018-19771-7.

41.

The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis.

Lawrence SM, Corriden R, Nizet V.

Microbiol Mol Biol Rev. 2018 Feb 7;82(1). pii: e00057-17. doi: 10.1128/MMBR.00057-17. Print 2018 Jun. Review.

42.

Broad-Spectrum Neutralization of Pore-Forming Toxins with Human Erythrocyte Membrane-Coated Nanosponges.

Chen Y, Chen M, Zhang Y, Lee JH, Escajadillo T, Gong H, Fang RH, Gao W, Nizet V, Zhang L.

Adv Healthc Mater. 2018 Jul;7(13):e1701366. doi: 10.1002/adhm.201701366. Epub 2018 Feb 13.

PMID:
29436150
43.

Innate Immune Interactions between Bacillus anthracis and Host Neutrophils.

Liu JZ, Ali SR, Bier E, Nizet V.

Front Cell Infect Microbiol. 2018 Jan 22;8:2. doi: 10.3389/fcimb.2018.00002. eCollection 2018.

44.

The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia.

Gupta N, Sinha R, Krasnodembskaya A, Xu X, Nizet V, Matthay MA, Griffin JH.

Stem Cells. 2018 May;36(5):796-806. doi: 10.1002/stem.2796. Epub 2018 Feb 14.

45.

Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance.

Choe D, Szubin R, Dahesh S, Cho S, Nizet V, Palsson B, Cho BK.

Sci Rep. 2018 Feb 2;8(1):2215. doi: 10.1038/s41598-018-20661-1.

46.

Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A Streptococcus.

Henningham A, Davies MR, Uchiyama S, van Sorge NM, Lund S, Chen KT, Walker MJ, Cole JN, Nizet V.

MBio. 2018 Jan 30;9(1). pii: e02294-17. doi: 10.1128/mBio.02294-17.

47.

Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies.

Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V.

Int J Antimicrob Agents. 2018 Mar;51(3):468-478. doi: 10.1016/j.ijantimicag.2017.12.032. Epub 2018 Jan 11. Review.

48.

Recurrent infection progressively disables host protection against intestinal inflammation.

Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD.

Science. 2017 Dec 22;358(6370). pii: eaao5610. doi: 10.1126/science.aao5610.

49.

Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and β-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms.

Catteau L, Reichmann NT, Olson J, Pinho MG, Nizet V, Van Bambeke F, Quetin-Leclercq J.

Molecules. 2017 Dec 16;22(12). pii: E2245. doi: 10.3390/molecules22122245.

50.

Telavancin for refractory MRSA bacteraemia in intermittent haemodialysis recipients.

Britt NS, Tirmizi S, Ritchie DJ, Topal JE, McManus D, Nizet V, Casabar E, Sakoulas G.

J Antimicrob Chemother. 2018 Mar 1;73(3):764-767. doi: 10.1093/jac/dkx437.

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