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Items: 7

1.

Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes.

Fenix AM, Neininger AC, Taneja N, Hyde K, Visetsouk MR, Garde RJ, Liu B, Nixon BR, Manalo AE, Becker JR, Crawley SW, Bader DM, Tyska MJ, Liu Q, Gutzman JH, Burnette DT.

Elife. 2018 Dec 12;7. pii: e42144. doi: 10.7554/eLife.42144.

2.

Nuclear localized Raf1 isoform alters DNA-dependent protein kinase activity and the DNA damage response.

Nixon BR, Sebag SC, Glennon MS, Hall EJ, Kounlavong ES, Freeman ML, Becker JR.

FASEB J. 2019 Jan;33(1):1138-1150. doi: 10.1096/fj.201800336R. Epub 2018 Aug 14.

3.

Alterations in sarcomere function modify the hyperplastic to hypertrophic transition phase of mammalian cardiomyocyte development.

Nixon BR, Williams AF, Glennon MS, de Feria AE, Sebag SC, Baldwin HS, Becker JR.

JCI Insight. 2017 Feb 23;2(4):e90656. doi: 10.1172/jci.insight.90656.

4.

Combined troponin I Ser-150 and Ser-23/24 phosphorylation sustains thin filament Ca(2+) sensitivity and accelerates deactivation in an acidic environment.

Nixon BR, Walton SD, Zhang B, Brundage EA, Little SC, Ziolo MT, Davis JP, Biesiadecki BJ.

J Mol Cell Cardiol. 2014 Jul;72:177-85. doi: 10.1016/j.yjmcc.2014.03.010. Epub 2014 Mar 19.

5.

Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation.

Nixon BR, Liu B, Scellini B, Tesi C, Piroddi N, Ogut O, Solaro RJ, Ziolo MT, Janssen PM, Davis JP, Poggesi C, Biesiadecki BJ.

Arch Biochem Biophys. 2013 Jul 1;535(1):30-8. doi: 10.1016/j.abb.2012.11.010. Epub 2012 Dec 8.

6.

AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function.

Nixon BR, Thawornkaiwong A, Jin J, Brundage EA, Little SC, Davis JP, Solaro RJ, Biesiadecki BJ.

J Biol Chem. 2012 Jun 1;287(23):19136-47. doi: 10.1074/jbc.M111.323048. Epub 2012 Apr 6.

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