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Items: 1 to 50 of 248

1.

Differential cell death decisions in the testis: evidence for an exclusive window of ferroptosis in round spermatids.

Bromfield EG, Walters JLH, Cafe SL, Bernstein IR, Stanger SJ, Anderson AL, Aitken RJ, McLaughlin EA, Dun MD, Gadella BM, Nixon B.

Mol Hum Reprod. 2019 Mar 13. pii: gaz015. doi: 10.1093/molehr/gaz015. [Epub ahead of print]

PMID:
30865280
2.

The contribution of epididymosomes to the sperm small RNA profile.

Trigg NA, Eamens AL, Nixon B.

Reproduction. 2019 Feb 1. pii: REP-18-0480.R3. doi: 10.1530/REP-18-0480. [Epub ahead of print] Review.

PMID:
30780129
3.

Investigation into the presence and functional significance of proinsulin C-peptide in the female germline.

Martin JH, Aitken RJ, Bromfield EG, Cafe SL, Sutherland JM, Frost ER, Nixon B, Lord T.

Biol Reprod. 2019 Jan 30. doi: 10.1093/biolre/ioz008. [Epub ahead of print]

PMID:
30715203
4.

Transcriptomic Profiling of the Tumor Microenvironment Reveals Distinct Subgroups of Clear Cell Renal Cell Cancer: Data from a Randomized Phase III Trial.

Hakimi AA, Voss MH, Kuo F, Sanchez A, Liu M, Nixon BG, Vuong L, Ostrovnaya I, Chen YB, Reuter V, Riaz N, Cheng Y, Patel P, Marker M, Reising A, Li MO, Chan TA, Motzer RJ.

Cancer Discov. 2019 Jan 8. doi: 10.1158/2159-8290.CD-18-0957. [Epub ahead of print]

PMID:
30622105
5.

DNA damage and repair in the female germline: contributions to ART.

Martin JH, Aitken RJ, Bromfield EG, Nixon B.

Hum Reprod Update. 2019 Mar 1;25(2):180-201. doi: 10.1093/humupd/dmy040.

PMID:
30541031
6.

Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes.

Fenix AM, Neininger AC, Taneja N, Hyde K, Visetsouk MR, Garde RJ, Liu B, Nixon BR, Manalo AE, Becker JR, Crawley SW, Bader DM, Tyska MJ, Liu Q, Gutzman JH, Burnette DT.

Elife. 2018 Dec 12;7. pii: e42144. doi: 10.7554/eLife.42144.

7.

Oxidative damage in naturally aged mouse oocytes is exacerbated by dysregulation of proteasomal activity.

Mihalas BP, Bromfield EG, Sutherland JM, De Iuliis GN, McLaughlin EA, Aitken RJ, Nixon B.

J Biol Chem. 2018 Dec 7;293(49):18944-18964. doi: 10.1074/jbc.RA118.005751. Epub 2018 Oct 10.

PMID:
30305393
8.

Probing the Origins of 1,800 MHz Radio Frequency Electromagnetic Radiation Induced Damage in Mouse Immortalized Germ Cells and Spermatozoa in vitro.

Houston BJ, Nixon B, King BV, Aitken RJ, De Iuliis GN.

Front Public Health. 2018 Sep 21;6:270. doi: 10.3389/fpubh.2018.00270. eCollection 2018.

9.

Oxidative Stress in the Male Germline: A Review of Novel Strategies to Reduce 4-Hydroxynonenal Production.

Walters JLH, De Iuliis GN, Nixon B, Bromfield EG.

Antioxidants (Basel). 2018 Oct 3;7(10). pii: E132. doi: 10.3390/antiox7100132. Review.

10.

Integrating Storytelling into a Communication Skills Teaching Program for Medical Oncology Fellows.

Shaw AC, McQuade JL, Reilley MJ, Nixon B, Baile WF, Epner DE.

J Cancer Educ. 2018 Sep 15. doi: 10.1007/s13187-018-1428-3. [Epub ahead of print]

PMID:
30219971
11.

Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation.

Nixon B, De Iuliis GN, Hart HM, Zhou W, Mathe A, Bernstein I, Anderson AL, Stanger SJ, Skerrett-Byrne DA, Jamaluddin MFB, Almazi JG, Bromfield EG, Larsen MR, Dun MD.

Mol Cell Proteomics. 2018 Sep 13. pii: mcp.RA118.000946. doi: 10.1074/mcp.RA118.000946. [Epub ahead of print]

12.

Analysis of Epididymal Protein Synthesis and Secretion.

Zhou W, Sipilä P, De Iuliis GN, Dun MD, Nixon B.

J Vis Exp. 2018 Aug 25;(138). doi: 10.3791/58308.

PMID:
30199011
13.

Nuclear localized Raf1 isoform alters DNA-dependent protein kinase activity and the DNA damage response.

Nixon BR, Sebag SC, Glennon MS, Hall EJ, Kounlavong ES, Freeman ML, Becker JR.

FASEB J. 2019 Jan;33(1):1138-1150. doi: 10.1096/fj.201800336R. Epub 2018 Aug 14.

PMID:
30106602
14.

Proteomic profiling of crocodile spermatozoa refutes the tenet that post-testicular maturation is restricted to mammals.

Nixon B, Johnston SD, Skerrett-Byrne DA, Anderson AL, Stanger SJ, Bromfield EG, Martin JH, Hansbro PM, Dun MD.

Mol Cell Proteomics. 2018 Aug 2. pii: mcp.RA118.000904. doi: 10.1074/mcp.RA118.000904. [Epub ahead of print]

15.

Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes.

Martin JH, Bromfield EG, Aitken RJ, Lord T, Nixon B.

Sci Rep. 2018 Jun 26;8(1):9685. doi: 10.1038/s41598-018-27892-2.

16.

Mouse quiescin sulfhydryl oxidases exhibit distinct epididymal luminal distribution with segment-specific sperm surface associations.

Wang TE, Li SH, Minabe S, Anderson AL, Dun MD, Maeda KI, Matsuda F, Chang HW, Nixon B, Tsai PJ.

Biol Reprod. 2018 Nov 1;99(5):1022-1033. doi: 10.1093/biolre/ioy125.

PMID:
29800099
17.

Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche.

Chakrabarti R, Celià-Terrassa T, Kumar S, Hang X, Wei Y, Choudhury A, Hwang J, Peng J, Nixon B, Grady JJ, DeCoste C, Gao J, van Es JH, Li MO, Aifantis I, Clevers H, Kang Y.

Science. 2018 Jun 29;360(6396). pii: eaan4153. doi: 10.1126/science.aan4153. Epub 2018 May 17.

PMID:
29773667
18.

Improved methods of DNA extraction from human spermatozoa that mitigate experimentally-induced oxidative DNA damage.

Xavier MJ, Nixon B, Roman SD, Aitken RJ.

PLoS One. 2018 Mar 26;13(3):e0195003. doi: 10.1371/journal.pone.0195003. eCollection 2018.

19.

Pharmacological inhibition of arachidonate 15-lipoxygenase protects human spermatozoa against oxidative stress.

Walters JLH, De Iuliis GN, Dun MD, Aitken RJ, McLaughlin EA, Nixon B, Bromfield EG.

Biol Reprod. 2018 Jun 1;98(6):784-794. doi: 10.1093/biolre/ioy058.

PMID:
29546268
20.

Characteristics of the Epididymal Luminal Environment Responsible for Sperm Maturation and Storage.

Zhou W, De Iuliis GN, Dun MD, Nixon B.

Front Endocrinol (Lausanne). 2018 Feb 28;9:59. doi: 10.3389/fendo.2018.00059. eCollection 2018. Review.

21.

Differential Effect of Food Sanitizers on Formation of Viable but Nonculturable Salmonella enterica in Poultry.

Purevdorj-Gage L, Nixon B, Bodine K, Xu Q, Doerrler WT.

J Food Prot. 2018 Mar;81(3):386-393. doi: 10.4315/0362-028X.JFP-17-335.

PMID:
29419335
22.

Heat exposure induces oxidative stress and DNA damage in the male germ line.

Houston BJ, Nixon B, Martin JH, De Iuliis GN, Trigg NA, Bromfield EG, McEwan KE, Aitken RJ.

Biol Reprod. 2018 Apr 1;98(4):593-606. doi: 10.1093/biolre/ioy009.

PMID:
29351587
23.

Molecular Mechanisms Responsible for Increased Vulnerability of the Ageing Oocyte to Oxidative Damage.

Mihalas BP, Redgrove KA, McLaughlin EA, Nixon B.

Oxid Med Cell Longev. 2017;2017:4015874. doi: 10.1155/2017/4015874. Epub 2017 Oct 18. Review.

24.

Tissue-Resident Cytolytic Innate Lymphocytes in Cancer.

Nixon BG, Li MO.

J Immunol. 2018 Jan 15;200(2):408-414. doi: 10.4049/jimmunol.1701124. Review.

25.

Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis.

Zhou W, Anderson AL, Turner AP, De Iuliis GN, McCluskey A, McLaughlin EA, Nixon B.

Mol Hum Reprod. 2017 Oct 1;23(10):657-673. doi: 10.1093/molehr/gax044.

PMID:
29044420
26.

Foxp3-independent mechanism by which TGF-β controls peripheral T cell tolerance.

Oh SA, Liu M, Nixon BG, Kang D, Toure A, Bivona M, Li MO.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7536-E7544. doi: 10.1073/pnas.1706356114. Epub 2017 Aug 21.

27.

Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa.

Hutcheon K, McLaughlin EA, Stanger SJ, Bernstein IR, Dun MD, Eamens AL, Nixon B.

RNA Biol. 2017 Dec 2;14(12):1776-1790. doi: 10.1080/15476286.2017.1356569. Epub 2017 Sep 21.

28.

Synthesis and Self-Assembly of Cellulose Microfibrils from Reconstituted Cellulose Synthase.

Cho SH, Purushotham P, Fang C, Maranas C, Díaz-Moreno SM, Bulone V, Zimmer J, Kumar M, Nixon BT.

Plant Physiol. 2017 Sep;175(1):146-156. doi: 10.1104/pp.17.00619. Epub 2017 Aug 2.

29.

The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte.

Mihalas BP, De Iuliis GN, Redgrove KA, McLaughlin EA, Nixon B.

Sci Rep. 2017 Jul 24;7(1):6247. doi: 10.1038/s41598-017-06372-z.

30.

Electrophilic aldehyde products of lipid peroxidation selectively adduct to heat shock protein 90 and arylsulfatase A in stallion spermatozoa.

Hall SE, Aitken RJ, Nixon B, Smith ND, Gibb Z.

Biol Reprod. 2017 Jan 1;96(1):107-121. doi: 10.1095/biolreprod.116.145292.

PMID:
28395341
31.

Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.

Zhou W, De Iuliis GN, Turner AP, Reid AT, Anderson AL, McCluskey A, McLaughlin EA, Nixon B.

Biol Reprod. 2017 Jan 1;96(1):159-173. doi: 10.1095/biolreprod.116.145433.

PMID:
28395327
32.

Heat Shock Protein A2 (HSPA2): Regulatory Roles in Germ Cell Development and Sperm Function.

Nixon B, Bromfield EG, Cui J, De Iuliis GN.

Adv Anat Embryol Cell Biol. 2017;222:67-93. doi: 10.1007/978-3-319-51409-3_4. Review.

PMID:
28389751
33.

Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions†.

Katen AL, Sipilä P, Mitchell LA, Stanger SJ, Nixon B, Roman SD.

Biol Reprod. 2017 Apr 1;96(4):921-935. doi: 10.1093/biolre/iox021.

PMID:
28379345
34.

Cryopreservation of saltwater crocodile (Crocodylus porosus) spermatozoa.

Johnston SD, Qualischefski E, Cooper J, McLeod R, Lever J, Nixon B, Anderson AL, Hobbs R, Gosálvez J, López-Fernández C, Keeley T.

Reprod Fertil Dev. 2017 Oct;29(11):2235-2244. doi: 10.1071/RD16511.

PMID:
28356183
35.

Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells.

Bromfield EG, Mihalas BP, Dun MD, Aitken RJ, McLaughlin EA, Walters JL, Nixon B.

Biol Reprod. 2017 Mar 1;96(3):598-609. doi: 10.1093/biolre/iox005.

PMID:
28339608
36.

Alterations in sarcomere function modify the hyperplastic to hypertrophic transition phase of mammalian cardiomyocyte development.

Nixon BR, Williams AF, Glennon MS, de Feria AE, Sebag SC, Baldwin HS, Becker JR.

JCI Insight. 2017 Feb 23;2(4):e90656. doi: 10.1172/jci.insight.90656.

37.

Satb1: Restraining PD1 and T Cell Exhaustion.

Nixon BG, Li MO.

Immunity. 2017 Jan 17;46(1):3-5. doi: 10.1016/j.immuni.2017.01.002.

38.

Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse.

Bromfield EG, Aitken RJ, McLaughlin EA, Nixon B.

Mol Hum Reprod. 2017 Feb 10;23(2):91-105. doi: 10.1093/molehr/gaw074.

PMID:
27932549
39.

The effects of radiofrequency electromagnetic radiation on sperm function.

Houston BJ, Nixon B, King BV, De Iuliis GN, Aitken RJ.

Reproduction. 2016 Dec;152(6):R263-R276. Epub 2016 Sep 6. Review.

PMID:
27601711
40.

Formation and Dissociation of Sperm Bundles in Monotremes.

Nixon B, Ecroyd H, Dacheux JL, Dacheux F, Labas V, Johnston SD, Jones RC.

Biol Reprod. 2016 Oct;95(4):91. Epub 2016 Aug 24.

PMID:
27557648
41.

Dynamin 2 is essential for mammalian spermatogenesis.

Redgrove KA, Bernstein IR, Pye VJ, Mihalas BP, Sutherland JM, Nixon B, McCluskey A, Robinson PJ, Holt JE, McLaughlin EA.

Sci Rep. 2016 Oct 11;6:35084. doi: 10.1038/srep35084.

42.

Non-surgical sterilisation methods may offer a sustainable solution to feral horse (Equus caballus) overpopulation.

Hall SE, Nixon B, Aitken RJ.

Reprod Fertil Dev. 2017 Sep;29(9):1655-1666. doi: 10.1071/RD16200. Review.

PMID:
27700983
43.

Analysis of the effects of polyphenols on human spermatozoa reveals unexpected impacts on mitochondrial membrane potential, oxidative stress and DNA integrity; implications for assisted reproductive technology.

Aitken RJ, Muscio L, Whiting S, Connaughton HS, Fraser BA, Nixon B, Smith ND, De Iuliis GN.

Biochem Pharmacol. 2016 Dec 1;121:78-96. doi: 10.1016/j.bcp.2016.09.015. Epub 2016 Sep 19.

PMID:
27659810
44.

A single heterologously expressed plant cellulose synthase isoform is sufficient for cellulose microfibril formation in vitro.

Purushotham P, Cho SH, Díaz-Moreno SM, Kumar M, Nixon BT, Bulone V, Zimmer J.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11360-11365. Epub 2016 Sep 19.

45.

Biochemical alterations in the oocyte in support of early embryonic development.

Martin JH, Bromfield EG, Aitken RJ, Nixon B.

Cell Mol Life Sci. 2017 Feb;74(3):469-485. doi: 10.1007/s00018-016-2356-1. Epub 2016 Sep 7. Review.

PMID:
27604868
46.

Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes.

Katen AL, Chambers CG, Nixon B, Roman SD.

Biol Reprod. 2016 Oct 1;95(4):86. doi: 10.1095/biolreprod.116.139535. Epub 2016 Aug 31.

PMID:
27580987
47.

Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome.

Reilly JN, McLaughlin EA, Stanger SJ, Anderson AL, Hutcheon K, Church K, Mihalas BP, Tyagi S, Holt JE, Eamens AL, Nixon B.

Sci Rep. 2016 Aug 23;6:31794. doi: 10.1038/srep31794.

48.

Data on the concentrations of etoposide, PSC833, BAPTA-AM, and cycloheximide that do not compromise the vitality of mature mouse oocytes, parthenogencially activated and fertilized embryos.

Martin JH, Bromfield EG, Aitken RJ, Lord T, Nixon B.

Data Brief. 2016 Jul 30;8:1215-20. doi: 10.1016/j.dib.2016.07.046. eCollection 2016 Sep.

49.

Analysis of risk factors for elbow dysplasia in giant breed dogs.

Nemanic S, Nixon BK, Baltzer W.

Vet Comp Orthop Traumatol. 2016 Sep 20;29(5):369-77. doi: 10.3415/VCOT-15-05-0175. Epub 2016 Jul 29.

PMID:
27471099
50.

Identification of a key role for permeability glycoprotein in enhancing the cellular defense mechanisms of fertilized oocytes.

Martin JH, Nixon B, Lord T, Bromfield EG, Aitken RJ.

Dev Biol. 2016 Sep 1;417(1):63-76. doi: 10.1016/j.ydbio.2016.06.035. Epub 2016 Jul 7.

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