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Items: 1 to 50 of 107

1.

An Inactive Dispersin B Probe for Monitoring PNAG Production in Biofilm Formation.

Eddenden A, Kitova EN, Klassen JS, Nitz M.

ACS Chem Biol. 2020 Jan 21. doi: 10.1021/acschembio.9b00907. [Epub ahead of print]

PMID:
31917539
2.

Intrinsic Turn-on Response of Thioflavin T in Complexes.

Kung JCK, Vurgun N, Chen JC, Nitz M, Jockusch RA.

Chemistry. 2020 Jan 7. doi: 10.1002/chem.201905100. [Epub ahead of print]

PMID:
31910290
3.

Validation of l-Tellurienylalanine as a Phenylalanine Isostere.

Vurgun N, Nitz M.

Chembiochem. 2019 Nov 19. doi: 10.1002/cbic.201900635. [Epub ahead of print]

PMID:
31742805
4.

Signal Amplification for Imaging Mass Cytometry.

Rana R, Gómez-Biagi RF, Bassan J, Nitz M.

Bioconjug Chem. 2019 Nov 20;30(11):2805-2810. doi: 10.1021/acs.bioconjchem.9b00559. Epub 2019 Nov 6.

PMID:
31693335
5.

Synthesis of defined mono-de-N-acetylated β-(1→6)-N-acetyl-d-glucosamine oligosaccharides to characterize PgaB hydrolase activity.

Forman A, Pfoh R, Eddenden A, Howell PL, Nitz M.

Org Biomol Chem. 2019 Nov 6;17(43):9456-9466. doi: 10.1039/c9ob02079a.

PMID:
31642455
6.

Methods for analyzing tellurium imaging mass cytometry data.

Bassan J, Nitz M.

PLoS One. 2019 Sep 3;14(9):e0221714. doi: 10.1371/journal.pone.0221714. eCollection 2019.

7.

Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms.

Bamford NC, Le Mauff F, Subramanian AS, Yip P, Millán C, Zhang Y, Zacharias C, Forman A, Nitz M, Codée JDC, Usón I, Sheppard DC, Howell PL.

J Biol Chem. 2019 Sep 13;294(37):13833-13849. doi: 10.1074/jbc.RA119.009910. Epub 2019 Aug 15.

8.

DNA directed damage using a brominated DAPI derivative.

Digby EM, Rana R, Nitz M, Beharry AA.

Chem Commun (Camb). 2019 Aug 15;55(67):9971-9974. doi: 10.1039/c9cc03942b.

PMID:
31367709
9.

Lanthanide nanoparticles for high sensitivity multiparameter single cell analysis.

Pichaandi J, Zhao G, Bouzekri A, Lu E, Ornatsky O, Baranov V, Nitz M, Winnik MA.

Chem Sci. 2019 Jan 23;10(10):2965-2974. doi: 10.1039/c8sc04407d. eCollection 2019 Mar 14.

10.

TePhe, a tellurium-containing phenylalanine mimic, allows monitoring of protein synthesis in vivo with mass cytometry.

Bassan J, Willis LM, Vellanki RN, Nguyen A, Edgar LJ, Wouters BG, Nitz M.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8155-8160. doi: 10.1073/pnas.1821151116. Epub 2019 Apr 10.

11.

Modeling 3-D diffusion using queueing networks.

Honary V, Nitz M, Wysocki BJ, Wysocki TA.

Biosystems. 2019 May;179:17-23. doi: 10.1016/j.biosystems.2018.12.006. Epub 2018 Dec 27.

PMID:
30594592
12.

Monosaccharide inhibitors targeting carbohydrate esterase family 4 de-N-acetylases.

DiFrancesco BR, Morrison ZA, Nitz M.

Bioorg Med Chem. 2018 Nov 15;26(21):5631-5643. doi: 10.1016/j.bmc.2018.10.008. Epub 2018 Oct 12.

PMID:
30344002
13.

Tellurium-based mass cytometry barcode for live and fixed cells.

Willis LM, Park H, Watson MWL, Majonis D, Watson JL, Nitz M.

Cytometry A. 2018 Jul;93(7):685-694. doi: 10.1002/cyto.a.23495. Epub 2018 Jul 27.

14.

PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.

Little DJ, Pfoh R, Le Mauff F, Bamford NC, Notte C, Baker P, Guragain M, Robinson H, Pier GB, Nitz M, Deora R, Sheppard DC, Howell PL.

PLoS Pathog. 2018 Apr 23;14(4):e1006998. doi: 10.1371/journal.ppat.1006998. eCollection 2018 Apr.

15.

Highly Functionalized β-Cyclodextrins by Solid-Supported Synthesis.

Vurgun N, Nitz M.

Chemistry. 2018 Mar 20;24(17):4459-4467. doi: 10.1002/chem.201800028. Epub 2018 Feb 26.

PMID:
29389050
16.

A β-galactosidase probe for the detection of cellular senescence by mass cytometry.

Lumba MA, Willis LM, Santra S, Rana R, Schito L, Rey S, Wouters BG, Nitz M.

Org Biomol Chem. 2017 Aug 2;15(30):6388-6392. doi: 10.1039/c7ob01227f.

PMID:
28726964
17.

Site specific protein O-glucosylation with bacterial toxins.

Sun Y, Willis LM, Batchelder HR, Nitz M.

Chem Commun (Camb). 2016 Oct 27;52(88):13024-13026.

PMID:
27748773
18.

Isotopologous Organotellurium Probes Reveal Dynamic Hypoxia In Vivo with Cellular Resolution.

Edgar LJ, Vellanki RN, McKee TD, Hedley D, Wouters BG, Nitz M.

Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13159-13163. doi: 10.1002/anie.201607483.

PMID:
27709819
19.

Structural and functional analysis of de-N-acetylase PgaB from periodontopathogen Aggregatibacter actinomycetemcomitans.

Parthiban C, Varudharasu D, Shanmugam M, Gopal P, Ragunath C, Thomas L, Nitz M, Ramasubbu N.

Mol Oral Microbiol. 2017 Aug;32(4):324-340. doi: 10.1111/omi.12175. Epub 2016 Nov 24.

PMID:
27706922
20.

Access to Versatile β-Cyclodextrin Scaffolds through Guest-Mediated Monoacylation.

Vurgun N, Gómez-Biagi RF, Nitz M.

Chemistry. 2016 Jan 18;22(3):1062-9. doi: 10.1002/chem.201503131. Epub 2015 Dec 4.

PMID:
26636269
21.

The protein BpsB is a poly-β-1,6-N-acetyl-D-glucosamine deacetylase required for biofilm formation in Bordetella bronchiseptica.

Little DJ, Milek S, Bamford NC, Ganguly T, DiFrancesco BR, Nitz M, Deora R, Howell PL.

J Biol Chem. 2015 Sep 11;290(37):22827-40. doi: 10.1074/jbc.M115.672469. Epub 2015 Jul 22.

22.

Organotellurium scaffolds for mass cytometry reagent development.

Park H, Edgar LJ, Lumba MA, Willis LM, Nitz M.

Org Biomol Chem. 2015 Jul 7;13(25):7027-33. doi: 10.1039/c5ob00593k. Epub 2015 Jun 4.

PMID:
26040785
23.

Direct Staudinger-Phosphonite Reaction Provides Methylphosphonamidates as Inhibitors of CE4 De-N-acetylases.

Ariyakumaran R, Pokrovskaya V, Little DJ, Howell PL, Nitz M.

Chembiochem. 2015 Jun 15;16(9):1350-6. doi: 10.1002/cbic.201500091. Epub 2015 May 26.

PMID:
25864869
24.

Structural basis for the De-N-acetylation of Poly-β-1,6-N-acetyl-D-glucosamine in Gram-positive bacteria.

Little DJ, Bamford NC, Pokrovskaya V, Robinson H, Nitz M, Howell PL.

J Biol Chem. 2014 Dec 26;289(52):35907-17. doi: 10.1074/jbc.M114.611400. Epub 2014 Oct 30.

25.

Discovery and characterization of small molecules that target the GTPase Ral.

Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, Schwartz MA, Jones DN, Ross D, Meroueh SO, Theodorescu D.

Nature. 2014 Nov 20;515(7527):443-7. doi: 10.1038/nature13713. Epub 2014 Sep 14.

26.

Identification of hypoxic cells using an organotellurium tag compatible with mass cytometry.

Edgar LJ, Vellanki RN, Halupa A, Hedley D, Wouters BG, Nitz M.

Angew Chem Int Ed Engl. 2014 Oct 20;53(43):11473-7. doi: 10.1002/anie.201405233. Epub 2014 Sep 4.

PMID:
25195589
27.

Modification and periplasmic translocation of the biofilm exopolysaccharide poly-β-1,6-N-acetyl-D-glucosamine.

Little DJ, Li G, Ing C, DiFrancesco BR, Bamford NC, Robinson H, Nitz M, Pomès R, Howell PL.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11013-8. doi: 10.1073/pnas.1406388111. Epub 2014 Jul 3.

28.

Functional PEG-PAMAM-tetraphosphonate capped NaLnF₄ nanoparticles and their colloidal stability in phosphate buffer.

Zhao G, Tong L, Cao P, Nitz M, Winnik MA.

Langmuir. 2014 Jun 17;30(23):6980-9. doi: 10.1021/la501142v. Epub 2014 Jun 5.

29.

Film coating of nifedipine extended release pellets in a fluid bed coater with a Wurster insert.

de Souza LF, Nitz M, Taranto OP.

Biomed Res Int. 2014;2014:520758. doi: 10.1155/2014/520758. Epub 2014 Mar 18.

30.

A high-sensitivity lanthanide nanoparticle reporter for mass cytometry: tests on microgels as a proxy for cells.

Lin W, Hou Y, Lu Y, Abdelrahman AI, Cao P, Zhao G, Tong L, Qian J, Baranov V, Nitz M, Winnik MA.

Langmuir. 2014 Mar 25;30(11):3142-53. doi: 10.1021/la403627p. Epub 2014 Mar 11.

31.

Protecting-group-free O-glysosidation using p-toluenesulfonohydrazide and glycosyl chloride donors.

Williams RJ, Paul CE, Nitz M.

Carbohydr Res. 2014 Mar 11;386:73-7. doi: 10.1016/j.carres.2013.08.019. Epub 2013 Aug 27.

PMID:
24491844
32.

Nuclear anomalies in exfoliated buccal cells in healthy and diabetic individuals and the impact of a dietary intervention.

Müllner E, Brath H, Nersesyan A, Nitz M, Petschnig A, Wallner M, Knasmüller S, Wagner KH.

Mutagenesis. 2014 Jan;29(1):1-6. doi: 10.1093/mutage/get056. Epub 2013 Dec 5.

PMID:
24311117
33.

Functional characterization of Staphylococcus epidermidis IcaB, a de-N-acetylase important for biofilm formation.

Pokrovskaya V, Poloczek J, Little DJ, Griffiths H, Howell PL, Nitz M.

Biochemistry. 2013 Aug 13;52(32):5463-71. doi: 10.1021/bi400836g. Epub 2013 Aug 1.

PMID:
23866051
34.

CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated.

Overdevest JB, Knubel KH, Duex JE, Thomas S, Nitz MD, Harding MA, Smith SC, Frierson HF, Conaway M, Theodorescu D.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):E3588-96. doi: 10.1073/pnas.1113960109. Epub 2012 Sep 25.

35.

CD24 is an effector of HIF-1-driven primary tumor growth and metastasis.

Thomas S, Harding MA, Smith SC, Overdevest JB, Nitz MD, Frierson HF, Tomlins SA, Kristiansen G, Theodorescu D.

Cancer Res. 2012 Nov 1;72(21):5600-12. doi: 10.1158/0008-5472.CAN-11-3666. Epub 2012 Aug 27.

36.

Improving lanthanide nanocrystal colloidal stability in competitive aqueous buffer solutions using multivalent PEG-phosphonate ligands.

Cao P, Tong L, Hou Y, Zhao G, Guerin G, Winnik MA, Nitz M.

Langmuir. 2012 Sep 4;28(35):12861-70. doi: 10.1021/la302690h. Epub 2012 Aug 21. Erratum in: Langmuir. 2012 Oct 30;28(43):15425.

PMID:
22906305
37.

Aβ(1-42) assembly in the presence of scyllo-inositol derivatives: identification of an oxime linkage as important for the development of assembly inhibitors.

Shaw JE, Chio J, Dasgupta S, Lai AY, Mo GC, Pang F, Thomason LA, Yang AJ, Yip CM, Nitz M, McLaurin J.

ACS Chem Neurosci. 2012 Mar 21;3(3):167-77. doi: 10.1021/cn2000926. Epub 2011 Dec 23.

38.

Synthesis and evaluation of inhibitors of E. coli PgaB, a polysaccharide de-N-acetylase involved in biofilm formation.

Chibba A, Poloczek J, Little DJ, Howell PL, Nitz M.

Org Biomol Chem. 2012 Sep 21;10(35):7103-7. doi: 10.1039/c2ob26105g. Epub 2012 Aug 2.

PMID:
22855025
39.

Syntheses of carbocyclic analogues of α-D-glucosamine, α-D-mannose, α-D-mannuronic acid, β-L-idosamine, and β-L-gulose.

Sun Y, Nitz M.

J Org Chem. 2012 Sep 7;77(17):7401-10. doi: 10.1021/jo301240j. Epub 2012 Aug 14.

PMID:
22853437
40.

Protecting-group-free synthesis of glycosyl 1-phosphates.

Edgar LJ, Dasgupta S, Nitz M.

Org Lett. 2012 Aug 17;14(16):4226-9. doi: 10.1021/ol3019083. Epub 2012 Jul 30.

PMID:
22846058
41.

The structure- and metal-dependent activity of Escherichia coli PgaB provides insight into the partial de-N-acetylation of poly-β-1,6-N-acetyl-D-glucosamine.

Little DJ, Poloczek J, Whitney JC, Robinson H, Nitz M, Howell PL.

J Biol Chem. 2012 Sep 7;287(37):31126-37. doi: 10.1074/jbc.M112.390005. Epub 2012 Jul 18.

42.

Combining in situ proteolysis and mass spectrometry to crystallize Escherichia coli PgaB.

Little DJ, Whitney JC, Robinson H, Yip P, Nitz M, Howell PL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):842-5. doi: 10.1107/S1744309112022075. Epub 2012 Jun 28.

43.

Site-selective affinity labelling of maltose binding protein in bacterial cells.

Rullo A, Beharry AA, Gómez-Biagi RF, Zhao X, Nitz M.

Chembiochem. 2012 Apr 16;13(6):783-7. doi: 10.1002/cbic.201200046. Epub 2012 Feb 29. No abstract available.

PMID:
22378590
44.

In vivo uptake of β-amyloid by non-plaque associated microglia.

Hawkes CA, Deng L, Fenili D, Nitz M, McLaurin J.

Curr Alzheimer Res. 2012 Oct;9(8):890-901.

PMID:
22272621
45.

Associations between single-leg postural control and drop-landing mechanics in healthy women.

Durall CJ, Kernozek TW, Kersten M, Nitz M, Setz J, Beck S.

J Sport Rehabil. 2011 Nov;20(4):406-18.

PMID:
22012495
46.

Characterization of the poly-β-1,6-N-acetylglucosamine polysaccharide component of Burkholderia biofilms.

Yakandawala N, Gawande PV, LoVetri K, Cardona ST, Romeo T, Nitz M, Madhyastha S.

Appl Environ Microbiol. 2011 Dec;77(23):8303-9. doi: 10.1128/AEM.05814-11. Epub 2011 Oct 7.

47.

Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice.

McLarty K, Moran MD, Scollard DA, Chan C, Sabha N, Mukherjee J, Guha A, McLaurin J, Nitz M, Houle S, Wilson AA, Reilly RM, Vasdev N.

Nucl Med Biol. 2011 Oct;38(7):953-9. doi: 10.1016/j.nucmedbio.2011.02.017. Epub 2011 May 6.

PMID:
21982567
48.

Sodium/myo-Inositol transporters: substrate transport requirements and regional brain expression in the TgCRND8 mouse model of amyloid pathology.

Fenili D, Weng YQ, Aubert I, Nitz M, McLaurin J.

PLoS One. 2011;6(8):e24032. doi: 10.1371/journal.pone.0024032. Epub 2011 Aug 26.

49.

Development of mass cytometry methods for bacterial discrimination.

Leipold MD, Ornatsky O, Baranov V, Whitfield C, Nitz M.

Anal Biochem. 2011 Dec 1;419(1):1-8. doi: 10.1016/j.ab.2011.07.035. Epub 2011 Aug 5.

PMID:
21871432
50.

Mono-acylation of a polyamine-β-cyclodextrin based on guest mediated acyl migration.

Gómez-Biagi RF, Nitz M.

Chem Commun (Camb). 2011 Aug 14;47(30):8614-6. doi: 10.1039/c1cc12646f. Epub 2011 Jun 29.

PMID:
21713279

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