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Items: 1 to 50 of 152

1.

Platelet-derived growth factor receptor α/glial fibrillary acidic protein expressing peritumoral astrocytes associate with shorter median overall survival in glioblastoma patients.

Leiss L, Mega A, Olsson Bontell T, Nistér M, Smits A, Corvigno S, Rahman MA, Enger PØ, Miletic H, Östman A.

Glia. 2020 May;68(5):979-988. doi: 10.1002/glia.23756. Epub 2019 Nov 26.

PMID:
31769546
2.

The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria.

Yu R, Liu T, Ning C, Tan F, Jin SB, Lendahl U, Zhao J, Nistér M.

J Biol Chem. 2019 Nov 15;294(46):17262-17277. doi: 10.1074/jbc.RA119.008202. Epub 2019 Sep 18.

PMID:
31533986
3.

Astrocytes enhance glioblastoma growth.

Mega A, Hartmark Nilsen M, Leiss LW, Tobin NP, Miletic H, Sleire L, Strell C, Nelander S, Krona C, Hägerstrand D, Enger PØ, Nistér M, Östman A.

Glia. 2020 Feb;68(2):316-327. doi: 10.1002/glia.23718. Epub 2019 Sep 11.

PMID:
31509308
4.

EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.

Li S, Rodriguez J, Li W, Bullova P, Fell SM, Surova O, Westerlund I, Topcic D, Bergsland M, Stenman A, Muhr J, Nistér M, Holmberg J, Juhlin CC, Larsson C, von Kriegsheim A, Kaelin WG Jr, Schlisio S.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16997-17006. doi: 10.1073/pnas.1900748116. Epub 2019 Aug 2.

5.

Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery.

Yu R, Jin SB, Lendahl U, Nistér M, Zhao J.

EMBO J. 2019 Apr 15;38(8). pii: e99748. doi: 10.15252/embj.201899748. Epub 2019 Mar 6.

6.

Reduced Expression of PROX1 Transitions Glioblastoma Cells into a Mesenchymal Gene Expression Subtype.

Goudarzi KM, Espinoza JA, Guo M, Bartek J, Nistér M, Lindström MS, Hägerstrand D.

Cancer Res. 2018 Oct 15;78(20):5901-5916. doi: 10.1158/0008-5472.CAN-18-0320. Epub 2018 Aug 22.

7.

Aberrant expression of genes associated with stemness and cancer in endometria and endometrioma in a subset of women with endometriosis.

Ponandai-Srinivasan S, Andersson KL, Nister M, Saare M, Hassan HA, Varghese SJ, Peters M, Salumets A, Gemzell-Danielsson K, Lalitkumar PGL.

Hum Reprod. 2018 Oct 1;33(10):1924-1938. doi: 10.1093/humrep/dey241.

PMID:
30020448
8.

Glycosylation controls sodium-calcium exchanger 3 sub-cellular localization during cell cycle.

Liu T, Zhao J, Ibarra C, Garcia MU, Uhlén P, Nistér M.

Eur J Cell Biol. 2018 Apr;97(3):190-203. doi: 10.1016/j.ejcb.2018.02.004. Epub 2018 Feb 28.

9.

SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells.

Kurtsdotter I, Topcic D, Karlén A, Singla B, Hagey DW, Bergsland M, Siesjö P, Nistér M, Carlson JW, Lefebvre V, Persson O, Holmberg J, Muhr J.

Cancer Res. 2017 Sep 15;77(18):4985-4997. doi: 10.1158/0008-5472.CAN-17-0704. Epub 2017 Jul 7.

10.

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff.

Yu R, Liu T, Jin SB, Ning C, Lendahl U, Nistér M, Zhao J.

Sci Rep. 2017 Apr 13;7(1):880. doi: 10.1038/s41598-017-00853-x.

11.

Erratum to: Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells.

Ma Y, Miao Y, Peng Z, Sandgren J, De Ståhl TD, Huss M, Lennartsson L, Liu Y, Nistér M, Nilsson S, Li C.

Springerplus. 2016 Dec 8;5(1):2084. doi: 10.1186/s40064-016-3759-z. eCollection 2016.

12.

Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells.

Ma Y, Miao Y, Peng Z, Sandgren J, De Ståhl TD, Huss M, Lennartsson L, Liu Y, Nistér M, Nilsson S, Li C.

Springerplus. 2016 Oct 24;5(1):1861. eCollection 2016. Erratum in: Springerplus. 2016 Dec 8;5(1):2084.

13.

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

Roodakker KR, Elsir T, Edqvist PD, Hägerstrand D, Carlson J, Lysiak M, Henriksson R, Pontén F, Rosell J, Söderkvist P, Stupp R, Tchougounova E, Nistér M, Malmström A, Smits A.

Oncotarget. 2016 Nov 8;7(45):72431-72442. doi: 10.18632/oncotarget.11957.

14.

Improving the Prediction of Prostate Cancer Overall Survival by Supplementing Readily Available Clinical Data with Gene Expression Levels of IGFBP3 and F3 in Formalin-Fixed Paraffin Embedded Core Needle Biopsy Material.

Peng Z, Andersson K, Lindholm J, Dethlefsen O, Pramana S, Pawitan Y, Nistér M, Nilsson S, Li C.

PLoS One. 2016 Jan 5;11(1):e0145545. doi: 10.1371/journal.pone.0145545. eCollection 2016.

15.

NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape.

Holmberg Olausson K, Elsir T, Moazemi Goudarzi K, Nistér M, Lindström MS.

Sci Rep. 2015 Nov 12;5:16495. doi: 10.1038/srep16495.

16.

Whole Exome- and mRNA-Sequencing of an AT/RT Case Reveals Few Somatic Mutations and Several Deregulated Signalling Pathways in the Context of SMARCB1 Deficiency.

Sandgren J, Holm S, Marino AM, Asmundsson J, Grillner P, Nistér M, Díaz de Ståhl T.

Biomed Res Int. 2015;2015:862039. doi: 10.1155/2015/862039. Epub 2015 Aug 12.

17.

mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels.

Goudarzi KM, Nistér M, Lindström MS.

Cancer Biol Ther. 2014;15(11):1499-514. doi: 10.4161/15384047.2014.955743.

18.

Loss of nucleolar histone chaperone NPM1 triggers rearrangement of heterochromatin and synergizes with a deficiency in DNA methyltransferase DNMT3A to drive ribosomal DNA transcription.

Holmberg Olausson K, Nistér M, Lindström MS.

J Biol Chem. 2014 Dec 12;289(50):34601-19. doi: 10.1074/jbc.M114.569244. Epub 2014 Oct 27.

19.

Operator dependent choice of prostate cancer biopsy has limited impact on a gene signature analysis for the highly expressed genes IGFBP3 and F3 in prostate cancer epithelial cells.

Peng Z, Andersson K, Lindholm J, Bodin I, Pramana S, Pawitan Y, Nistér M, Nilsson S, Li C.

PLoS One. 2014 Oct 8;9(10):e109610. doi: 10.1371/journal.pone.0109610. eCollection 2014.

20.

Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas.

Holmberg Olausson K, Maire CL, Haidar S, Ling J, Learner E, Nistér M, Ligon KL.

PLoS One. 2014 Sep 3;9(9):e106694. doi: 10.1371/journal.pone.0106694. eCollection 2014.

21.

An expression signature at diagnosis to estimate prostate cancer patients' overall survival.

Peng Z, Skoog L, Hellborg H, Jonstam G, Wingmo IL, Hjälm-Eriksson M, Harmenberg U, Cedermark GC, Andersson K, Ahrlund-Richter L, Pramana S, Pawitan Y, Nistér M, Nilsson S, Li C.

Prostate Cancer Prostatic Dis. 2014 Mar;17(1):81-90. doi: 10.1038/pcan.2013.57. Epub 2014 Jan 7.

22.

A study of embryonic stem cell-related proteins in human astrocytomas: identification of Nanog as a predictor of survival.

Elsir T, Edqvist PH, Carlson J, Ribom D, Bergqvist M, Ekman S, Popova SN, Alafuzoff I, Ponten F, Nistér M, Smits A.

Int J Cancer. 2014 Mar 1;134(5):1123-31. doi: 10.1002/ijc.28441. Epub 2013 Sep 16.

23.

EpCAM associates with endoplasmic reticulum aminopeptidase 2 (ERAP2) in breast cancer cells.

Gadalla SE, Öjemalm K, Vasquez PL, Nilsson I, Ericsson C, Zhao J, Nistér M.

Biochem Biophys Res Commun. 2013 Sep 20;439(2):203-8. doi: 10.1016/j.bbrc.2013.08.059. Epub 2013 Aug 26.

PMID:
23988446
24.

The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics.

Liu T, Yu R, Jin SB, Han L, Lendahl U, Zhao J, Nistér M.

Exp Cell Res. 2013 Nov 1;319(18):2893-904. doi: 10.1016/j.yexcr.2013.07.010. Epub 2013 Jul 20.

PMID:
23880462
25.

Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates.

Zhao J, Lendahl U, Nistér M.

Cell Mol Life Sci. 2013 Mar;70(6):951-76. doi: 10.1007/s00018-012-1066-6. Epub 2012 Jul 18. Review.

26.

Transcription factor PROX1: its role in development and cancer.

Elsir T, Smits A, Lindström MS, Nistér M.

Cancer Metastasis Rev. 2012 Dec;31(3-4):793-805. doi: 10.1007/s10555-012-9390-8. Review.

PMID:
22733308
27.

GABA-A channel subunit expression in human glioma correlates with tumor histology and clinical outcome.

Smits A, Jin Z, Elsir T, Pedder H, Nistér M, Alafuzoff I, Dimberg A, Edqvist PH, Pontén F, Aronica E, Birnir B.

PLoS One. 2012;7(5):e37041. doi: 10.1371/journal.pone.0037041. Epub 2012 May 17.

28.

PDGF and PDGF receptors in glioma.

Nazarenko I, Hede SM, He X, Hedrén A, Thompson J, Lindström MS, Nistér M.

Ups J Med Sci. 2012 May;117(2):99-112. doi: 10.3109/03009734.2012.665097. Epub 2012 Apr 17. Review.

29.

p53 -Dependent and -Independent Nucleolar Stress Responses.

Holmberg Olausson K, Nistér M, Lindström MS.

Cells. 2012 Oct 15;1(4):774-98. doi: 10.3390/cells1040774.

30.

Novel amplifications in pediatric medulloblastoma identified by genome-wide copy number profiling.

Nord H, Pfeifer S, Nilsson P, Sandgren J, Popova S, Strömberg B, Alafuzoff I, Nistér M, Díaz de Ståhl T.

J Neurooncol. 2012 Mar;107(1):37-49. doi: 10.1007/s11060-011-0716-0. Epub 2011 Oct 7.

PMID:
21979893
31.

Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile.

Hägerstrand D, He X, Bradic Lindh M, Hoefs S, Hesselager G, Ostman A, Nistér M.

Neuro Oncol. 2011 Nov;13(11):1178-91. doi: 10.1093/neuonc/nor113. Epub 2011 Sep 22.

32.

RAD51 can inhibit PDGF-B-induced gliomagenesis and genomic instability.

Westermark UK, Lindberg N, Roswall P, Bråsäter D, Helgadottir HR, Hede SM, Zetterberg A, Jasin M, Nistér M, Uhrbom L.

Neuro Oncol. 2011 Dec;13(12):1277-87. doi: 10.1093/neuonc/nor131. Epub 2011 Sep 16.

33.

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission.

Zhao J, Liu T, Jin S, Wang X, Qu M, Uhlén P, Tomilin N, Shupliakov O, Lendahl U, Nistér M.

EMBO J. 2011 Jun 24;30(14):2762-78. doi: 10.1038/emboj.2011.198.

34.

PROX1 is a predictor of survival for gliomas WHO grade II.

Elsir T, Qu M, Berntsson SG, Orrego A, Olofsson T, Lindström MS, Nistér M, von Deimling A, Hartmann C, Ribom D, Smits A.

Br J Cancer. 2011 May 24;104(11):1747-54. doi: 10.1038/bjc.2011.162. Epub 2011 May 10.

35.

Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells.

Nazarenko I, Hedrén A, Sjödin H, Orrego A, Andrae J, Afink GB, Nistér M, Lindström MS.

PLoS One. 2011 Apr 7;6(4):e18303. doi: 10.1371/journal.pone.0018303.

36.

Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma.

Holmberg J, He X, Peredo I, Orrego A, Hesselager G, Ericsson C, Hovatta O, Oba-Shinjo SM, Marie SK, Nistér M, Muhr J.

PLoS One. 2011 Mar 31;6(3):e18454. doi: 10.1371/journal.pone.0018454.

37.

Uncoupling of the ERα regulated morphological phenotype from the cancer stem cell phenotype in human breast cancer cell lines.

Gadalla SE, Alexandraki A, Lindström MS, Nistér M, Ericsson C.

Biochem Biophys Res Commun. 2011 Feb 25;405(4):581-7. doi: 10.1016/j.bbrc.2011.01.072. Epub 2011 Jan 23.

PMID:
21266162
38.

Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors.

Hede SM, Nazarenko I, Nistér M, Lindström MS.

J Oncol. 2011;2011:852970. doi: 10.1155/2011/852970. Epub 2010 Dec 15.

39.

Blood plasma handling for protein analysis.

Ericsson C, Nistér M.

Methods Mol Biol. 2011;675:333-41. doi: 10.1007/978-1-59745-423-0_20.

PMID:
20949401
40.

Handling of solid brain tumor tissue for protein analysis.

Ericsson C, Nistér M.

Methods Mol Biol. 2011;675:327-32. doi: 10.1007/978-1-59745-423-0_19.

PMID:
20949400
41.

Protein extraction from solid tissue.

Ericsson C, Nistér M.

Methods Mol Biol. 2011;675:307-12. doi: 10.1007/978-1-59745-423-0_17.

PMID:
20949398
42.

Meta-analysis of cancer gene expression signatures reveals new cancer genes, SAGE tags and tumor associated regions of co-regulation.

Kavak E, Unlü M, Nistér M, Koman A.

Nucleic Acids Res. 2010 Nov;38(20):7008-21. doi: 10.1093/nar/gkq574. Epub 2010 Jul 9.

43.

Prognostic but not predictive role of platelet-derived growth factor receptors in patients with recurrent glioblastoma.

Paulsson J, Lindh MB, Jarvius M, Puputti M, Nistér M, Nupponen NN, Paulus W, Söderberg O, Dresemann G, von Deimling A, Joensuu H, Ostman A, Hasselblatt M.

Int J Cancer. 2011 Apr 15;128(8):1981-8. doi: 10.1002/ijc.25528.

44.

PI3K/PTEN/Akt pathway status affects the sensitivity of high-grade glioma cell cultures to the insulin-like growth factor-1 receptor inhibitor NVP-AEW541.

Hägerstrand D, Lindh MB, Peña C, Garcia-Echeverria C, Nistér M, Hofmann F, Ostman A.

Neuro Oncol. 2010 Sep;12(9):967-75. doi: 10.1093/neuonc/noq029. Epub 2010 Apr 8.

45.

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha.

Seidel S, Garvalov BK, Wirta V, von Stechow L, Schänzer A, Meletis K, Wolter M, Sommerlad D, Henze AT, Nistér M, Reifenberger G, Lundeberg J, Frisén J, Acker T.

Brain. 2010 Apr;133(Pt 4):983-95. doi: 10.1093/brain/awq042.

PMID:
20375133
46.
47.

Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma.

Yin S, Girnita A, Strömberg T, Khan Z, Andersson S, Zheng H, Ericsson C, Axelson M, Nistér M, Larsson O, Ekström TJ, Girnita L.

Neuro Oncol. 2010 Jan;12(1):19-27. doi: 10.1093/neuonc/nop008. Epub 2009 Oct 20.

48.

Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas.

Qu M, Jiao H, Zhao J, Ren ZP, Smits A, Kere J, Nistér M.

Neuropathol Appl Neurobiol. 2010 Apr;36(3):198-210. doi: 10.1111/j.1365-2990.2010.01070.x. Epub 2010 Feb 26.

PMID:
20132488
49.

Expression of PROX1 Is a common feature of high-grade malignant astrocytic gliomas.

Elsir T, Eriksson A, Orrego A, Lindström MS, Nistér M.

J Neuropathol Exp Neurol. 2010 Feb;69(2):129-38. doi: 10.1097/NEN.0b013e3181ca4767.

PMID:
20084020
50.

The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-beta-mediated growth regulation.

Ponnamperuma RM, King KE, Elsir T, Glick AB, Wahl GM, Nister M, Weinberg WC.

J Pathol. 2009 Oct;219(2):263-74. doi: 10.1002/path.2600.

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