Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 46

1.

H-Ras activation and fibroblast-induced TGF-β signaling promote laminin-332 accumulation and invasion in cutaneous squamous cell carcinoma.

Siljamäki E, Rappu P, Riihilä P, Nissinen L, Kähäri VM, Heino J.

Matrix Biol. 2019 Oct 24. pii: S0945-053X(19)30217-3. doi: 10.1016/j.matbio.2019.09.001. [Epub ahead of print]

PMID:
31655292
2.

Complement System in Cutaneous Squamous Cell Carcinoma.

Riihilä P, Nissinen L, Knuutila J, Rahmati Nezhad P, Viiklepp K, Kähäri VM.

Int J Mol Sci. 2019 Jul 19;20(14). pii: E3550. doi: 10.3390/ijms20143550. Review.

3.

Tumour-cell-derived complement components C1r and C1s promote growth of cutaneous squamous cell carcinoma.

Riihilä P, Viiklepp K, Nissinen L, Farshchian M, Kallajoki M, Kivisaari A, Meri S, Peltonen J, Peltonen S, Kähäri VM.

Br J Dermatol. 2019 May 3. doi: 10.1111/bjd.18095. [Epub ahead of print]

PMID:
31049937
4.

Tumor cell-specific Serpin A1 expression in vulvar squamous cell carcinoma.

Lagerstedt M, Huotari-Orava R, Nyberg R, Nissinen L, Farshchian M, Laasanen SL, Snellman E, Mäenpää JU, Kähäri VM.

Arch Gynecol Obstet. 2019 May;299(5):1345-1351. doi: 10.1007/s00404-018-5015-y. Epub 2019 Jan 4.

5.

Long non-coding RNA PICSAR decreases adhesion and promotes migration of squamous carcinoma cells by downregulating α2β1 and α5β1 integrin expression.

Piipponen M, Heino J, Kähäri VM, Nissinen L.

Biol Open. 2018 Nov 14;7(11). pii: bio037044. doi: 10.1242/bio.037044.

6.

Tumor cell-specific AIM2 regulates growth and invasion of cutaneous squamous cell carcinoma.

Farshchian M, Nissinen L, Siljamäki E, Riihilä P, Piipponen M, Kivisaari A, Kallajoki M, Grénman R, Peltonen J, Peltonen S, Quint KD, Bavinck JNB, Kähäri VM.

Oncotarget. 2017 Jul 11;8(28):45825-45836. doi: 10.18632/oncotarget.17573.

7.

Complement Component C3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma.

Riihilä P, Nissinen L, Farshchian M, Kallajoki M, Kivisaari A, Meri S, Grénman R, Peltonen S, Peltonen J, Pihlajaniemi T, Heljasvaara R, Kähäri VM.

Am J Pathol. 2017 May;187(5):1186-1197. doi: 10.1016/j.ajpath.2017.01.006. Epub 2017 Mar 17.

8.

Expression of claudin-11 by tumor cells in cutaneous squamous cell carcinoma is dependent on the activity of p38δ.

Nissinen L, Siljamäki E, Riihilä P, Piipponen M, Farshchian M, Kivisaari A, Kallajoki M, Raiko L, Peltonen J, Peltonen S, Kähäri VM.

Exp Dermatol. 2017 Sep;26(9):771-777. doi: 10.1111/exd.13278. Epub 2017 Apr 10.

PMID:
27992079
9.

MicroRNA-203 Inversely Correlates with Differentiation Grade, Targets c-MYC, and Functions as a Tumor Suppressor in cSCC.

Lohcharoenkal W, Harada M, Lovén J, Meisgen F, Landén NX, Zhang L, Lapins J, Mahapatra KD, Shi H, Nissinen L, Kähäri VM, Ståhle M, Sonkoly E, Grandér D, Arsenian-Henriksson M, Pivarcsi A.

J Invest Dermatol. 2016 Dec;136(12):2485-2494. doi: 10.1016/j.jid.2016.06.630. Epub 2016 Jul 22.

10.

New perspectives on role of tumor microenvironment in progression of cutaneous squamous cell carcinoma.

Nissinen L, Farshchian M, Riihilä P, Kähäri VM.

Cell Tissue Res. 2016 Sep;365(3):691-702. doi: 10.1007/s00441-016-2457-z. Epub 2016 Jul 14. Review.

PMID:
27411692
11.

Dasatinib promotes apoptosis of cutaneous squamous carcinoma cells by regulating activation of ERK1/2.

Farshchian M, Nissinen L, Grénman R, Kähäri VM.

Exp Dermatol. 2017 Jan;26(1):89-92. doi: 10.1111/exd.13109. Epub 2016 Dec 20. No abstract available.

PMID:
27305645
12.

Long Noncoding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity.

Piipponen M, Nissinen L, Farshchian M, Riihilä P, Kivisaari A, Kallajoki M, Peltonen J, Peltonen S, Kähäri VM.

J Invest Dermatol. 2016 Aug;136(8):1701-1710. doi: 10.1016/j.jid.2016.03.028. Epub 2016 Apr 2.

13.

Platelet response to a small molecule inhibitor of α2β1 integrin is associated with ITGA2 C807T dimorphism.

Nissinen L, Rappu P, Ollikka P, Nieminen J, Marjamäki A, Heino J.

Platelets. 2016 Jun;27(4):378-80. doi: 10.3109/09537104.2015.1095877. Epub 2015 Nov 10.

PMID:
26556301
14.

Collagen Turnover in Wound Repair--A Macrophage Connection.

Nissinen LM, Kähäri VM.

J Invest Dermatol. 2015 Oct;135(10):2350-2352. doi: 10.1038/jid.2015.246.

15.

Sulfonamide inhibitors of α2β1 integrin reveal the essential role of collagen receptors in in vivo models of inflammation.

Nissinen L, Ojala M, Langen B, Dost R, Pihlavisto M, Käpylä J, Marjamäki A, Heino J.

Pharmacol Res Perspect. 2015 Jun;3(3):e00146. doi: 10.1002/prp2.146. Epub 2015 May 15.

16.

EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma.

Farshchian M, Nissinen L, Siljamäki E, Riihilä P, Toriseva M, Kivisaari A, Ala-Aho R, Kallajoki M, Veräjänkorva E, Honkanen HK, Heljasvaara R, Pihlajaniemi T, Grénman R, Peltonen J, Peltonen S, Kähäri VM.

J Invest Dermatol. 2015 Jul;135(7):1882-1892. doi: 10.1038/jid.2015.104. Epub 2015 Mar 19.

17.

Complement factor I promotes progression of cutaneous squamous cell carcinoma.

Riihilä P, Nissinen L, Farshchian M, Kivisaari A, Ala-Aho R, Kallajoki M, Grénman R, Meri S, Peltonen S, Peltonen J, Kähäri VM.

J Invest Dermatol. 2015 Feb;135(2):579-588. doi: 10.1038/jid.2014.376. Epub 2014 Sep 3.

18.

Matrix metalloproteinases in inflammation.

Nissinen L, Kähäri VM.

Biochim Biophys Acta. 2014 Aug;1840(8):2571-80. doi: 10.1016/j.bbagen.2014.03.007. Epub 2014 Mar 14. Review.

PMID:
24631662
19.

Complement factor H: a biomarker for progression of cutaneous squamous cell carcinoma.

Riihilä PM, Nissinen LM, Ala-Aho R, Kallajoki M, Grénman R, Meri S, Peltonen S, Peltonen J, Kähäri VM.

J Invest Dermatol. 2014 Feb;134(2):498-506. doi: 10.1038/jid.2013.346. Epub 2013 Aug 12.

20.

p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes.

Siljamäki E, Raiko L, Toriseva M, Nissinen L, Näreoja T, Peltonen J, Kähäri VM, Peltonen S.

Arch Dermatol Res. 2014 Mar;306(2):131-41. doi: 10.1007/s00403-013-1391-0. Epub 2013 Jul 16.

PMID:
23856837
21.

Novel α2β1 integrin inhibitors reveal that integrin binding to collagen under shear stress conditions does not require receptor preactivation.

Nissinen L, Koivunen J, Käpylä J, Salmela M, Nieminen J, Jokinen J, Sipilä K, Pihlavisto M, Pentikäinen OT, Marjamäki A, Heino J.

J Biol Chem. 2012 Dec 28;287(53):44694-702. doi: 10.1074/jbc.M111.309450. Epub 2012 Nov 6.

22.

ADAMTS5: A New Player in the Vascular Field.

Nissinen L, Kähäri VM.

Am J Pathol. 2012 Sep;181(3):743-5. doi: 10.1016/j.ajpath.2012.07.002. Epub 2012 Jul 20.

PMID:
22824241
23.

Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis.

Pollari S, Käkönen RS, Mohammad KS, Rissanen JP, Halleen JM, Wärri A, Nissinen L, Pihlavisto M, Marjamäki A, Perälä M, Guise TA, Kallioniemi O, Käkönen SM.

Mol Cancer Res. 2012 May;10(5):597-604. doi: 10.1158/1541-7786.MCR-11-0482. Epub 2012 Apr 20.

24.

Calpains promote α2β1 integrin turnover in nonrecycling integrin pathway.

Rintanen N, Karjalainen M, Alanko J, Paavolainen L, Mäki A, Nissinen L, Lehkonen M, Kallio K, Cheng RH, Upla P, Ivaska J, Marjomäki V.

Mol Biol Cell. 2012 Feb;23(3):448-63. doi: 10.1091/mbc.E11-06-0548. Epub 2011 Dec 7.

25.

Fluorescent small molecule probe to modulate and explore α2β1 integrin function.

Koivunen JT, Nissinen L, Käpylä J, Jokinen J, Pihlavisto M, Marjamäki A, Heino J, Huuskonen J, Pentikäinen OT.

J Am Chem Soc. 2011 Sep 21;133(37):14558-61. doi: 10.1021/ja206086c. Epub 2011 Aug 30.

PMID:
21863823
26.

A small-molecule inhibitor of integrin alpha2 beta1 introduces a new strategy for antithrombotic therapy.

Nissinen L, Pentikäinen OT, Jouppila A, Käpylä J, Ojala M, Nieminen J, Lipsanen A, Lappalainen H, Eckes B, Johnson MS, Lassila R, Marjamäki A, Heino J.

Thromb Haemost. 2010 Feb;103(2):387-97. doi: 10.1160/TH09-06-0358. Epub 2009 Dec 1.

PMID:
20126829
27.

Molecular mechanism of alpha2beta1 integrin interaction with human echovirus 1.

Jokinen J, White DJ, Salmela M, Huhtala M, Käpylä J, Sipilä K, Puranen JS, Nissinen L, Kankaanpää P, Marjomäki V, Hyypiä T, Johnson MS, Heino J.

EMBO J. 2010 Jan 6;29(1):196-208. doi: 10.1038/emboj.2009.326. Epub 2009 Nov 19.

28.

Calpain 1 and 2 are required for RNA replication of echovirus 1.

Upla P, Marjomäki V, Nissinen L, Nylund C, Waris M, Hyypiä T, Heino J.

J Virol. 2008 Feb;82(3):1581-90. Epub 2007 Nov 21.

29.

O-sulfated bacterial polysaccharides with low anticoagulant activity inhibit metastasis.

Borgenström M, Wärri A, Hiilesvuo K, Käkönen R, Käkönen S, Nissinen L, Pihlavisto M, Marjamäki A, Vlodavsky I, Naggi A, Torri G, Casu B, Veromaa T, Salmivirta M, Elenius K.

Semin Thromb Hemost. 2007 Jul;33(5):547-56.

PMID:
17629853
30.

Small molecule designed to target metal binding site in the alpha2I domain inhibits integrin function.

Käpylä J, Pentikäinen OT, Nyrönen T, Nissinen L, Lassander S, Jokinen J, Lahti M, Marjamäki A, Johnson MS, Heino J.

J Med Chem. 2007 May 31;50(11):2742-6. Epub 2007 Apr 21.

PMID:
17447751
31.

Collagen XVII promotes integrin-mediated squamous cell carcinoma transmigration--a novel role for alphaIIb integrin and tirofiban.

Parikka M, Nissinen L, Kainulainen T, Bruckner-Tuderman L, Salo T, Heino J, Tasanen K.

Exp Cell Res. 2006 May 1;312(8):1431-8. Epub 2006 Feb 20.

PMID:
16487966
32.

Regulation of prostate cell collagen receptors by malignant transformation.

Mirtti T, Nylund C, Lehtonen J, Hiekkanen H, Nissinen L, Kallajoki M, Alanen K, Gullberg D, Heino J.

Int J Cancer. 2006 Feb 15;118(4):889-98.

33.

The fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix.

Käpylä J, Jäälinoja J, Tulla M, Ylöstalo J, Nissinen L, Viitasalo T, Vehviläinen P, Marjomäki V, Nykvist P, Säämänen AM, Farndale RW, Birk DE, Ala-Kokko L, Heino J.

J Biol Chem. 2004 Dec 3;279(49):51677-87. Epub 2004 Sep 21.

34.

Expression of alpha7beta1 integrin splicing variants during skeletal muscle regeneration.

Kääriäinen M, Nissinen L, Kaufman S, Sonnenberg A, Järvinen M, Heino J, Kalimo H.

Am J Pathol. 2002 Sep;161(3):1023-31.

35.

Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

Ivaska J, Nissinen L, Immonen N, Eriksson JE, Kähäri VM, Heino J.

Mol Cell Biol. 2002 Mar;22(5):1352-9.

36.

Internalization of echovirus 1 in caveolae.

Marjomäki V, Pietiäinen V, Matilainen H, Upla P, Ivaska J, Nissinen L, Reunanen H, Huttunen P, Hyypiä T, Heino J.

J Virol. 2002 Feb;76(4):1856-65.

37.

Selective binding of collagen subtypes by integrin alpha 1I, alpha 2I, and alpha 10I domains.

Tulla M, Pentikäinen OT, Viitasalo T, Käpylä J, Impola U, Nykvist P, Nissinen L, Johnson MS, Heino J.

J Biol Chem. 2001 Dec 21;276(51):48206-12. Epub 2001 Sep 25.

38.
39.

Integrin and dystrophin associated adhesion protein complexes during regeneration of shearing-type muscle injury.

Kääriäinen M, Kääriäinen J, Järvinen TL, Nissinen L, Heino J, Järvinen M, Kalimo H.

Neuromuscul Disord. 2000 Feb;10(2):121-32.

PMID:
10714587
40.
42.

Transcription of alpha2 integrin gene in osteosarcoma cells is enhanced by tumor promoters.

Nissinen L, Westermarck J, Koivisto L, Kähäri VM, Heino J.

Exp Cell Res. 1998 Aug 25;243(1):1-10.

PMID:
9716443
43.

Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development.

Johansson N, Saarialho-Kere U, Airola K, Herva R, Nissinen L, Westermarck J, Vuorio E, Heino J, Kähäri VM.

Dev Dyn. 1997 Mar;208(3):387-97.

44.

Bone morphogenetic protein-2 is a regulator of cell adhesion.

Nissinen L, Pirilä L, Heino J.

Exp Cell Res. 1997 Feb 1;230(2):377-85.

PMID:
9024797
45.

The genome of echovirus 11.

Dahllund L, Nissinen L, Pulli T, Hyttinen VP, Stanway G, Hyypiä T.

Virus Res. 1995 Feb;35(2):215-22.

PMID:
7762294
46.

Supplemental Content

Loading ...
Support Center