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Items: 1 to 50 of 107

1.

Sirtuin-3 Promotes Adipogenesis, Osteoclastogenesis, and Bone Loss in Aging Male Mice.

Ho L, Wang L, Roth TM, Pan Y, Verdin EM, Hsiao EC, Nissenson RA.

Endocrinology. 2017 Sep 1;158(9):2741-2753. doi: 10.1210/en.2016-1739.

2.

Role of Osteoblast Gi Signaling in Age-Related Bone Loss in Female Mice.

Millard SM, Wang L, Wattanachanya L, O'Carroll D, Fields AJ, Pang J, Kazakia G, Lotz JC, Nissenson RA.

Endocrinology. 2017 Jun 1;158(6):1715-1726. doi: 10.1210/en.2016-1365.

3.

Osteoblast-derived FGF9 regulates skeletal homeostasis.

Wang L, Roth T, Abbott M, Ho L, Wattanachanya L, Nissenson RA.

Bone. 2017 May;98:18-25. doi: 10.1016/j.bone.2016.12.005. Epub 2017 Feb 9.

4.

Gs/Gi Regulation of Bone Cell Differentiation: Review and Insights from Engineered Receptors.

Hsiao EC, Millard SM, Nissenson RA.

Horm Metab Res. 2016 Nov;48(11):689-699. Epub 2016 Sep 19. Review.

PMID:
27643449
5.

Dietary dried plum increases bone mass, suppresses proinflammatory cytokines and promotes attainment of peak bone mass in male mice.

Shahnazari M, Turner RT, Iwaniec UT, Wronski TJ, Li M, Ferruzzi MG, Nissenson RA, Halloran BP.

J Nutr Biochem. 2016 Aug;34:73-82. doi: 10.1016/j.jnutbio.2016.04.007. Epub 2016 May 10.

PMID:
27239754
6.

Negative Skeletal Effects of Locally Produced Adiponectin.

Abbott MJ, Roth TM, Ho L, Wang L, O'Carroll D, Nissenson RA.

PLoS One. 2015 Jul 31;10(7):e0134290. doi: 10.1371/journal.pone.0134290. eCollection 2015.

7.

Loss of Gi G-Protein-Coupled Receptor Signaling in Osteoblasts Accelerates Bone Fracture Healing.

Wang L, Hsiao EC, Lieu S, Scott M, O'Carroll D, Urrutia A, Conklin BR, Colnot C, Nissenson RA.

J Bone Miner Res. 2015 Oct;30(10):1896-904. doi: 10.1002/jbmr.2540. Epub 2015 May 14.

8.

Effects of blockade of endogenous Gi signaling in Tie2-expressing cells on bone formation in a mouse model of heterotopic ossification.

Wang L, Carroll DO, Liu X, Roth T, Kim H, Halloran B, Nissenson RA.

J Orthop Res. 2015 Aug;33(8):1212-7. doi: 10.1002/jor.22876. Epub 2015 May 20.

9.

Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs-G protein signaling in osteoblasts.

Wattanachanya L, Wang L, Millard SM, Lu WD, O'Carroll D, Hsiao EC, Conklin BR, Nissenson RA.

Exp Cell Res. 2015 May 1;333(2):289-302. doi: 10.1016/j.yexcr.2015.02.009. Epub 2015 Feb 20.

10.

CXCL12/CXCR4 signaling in the osteoblast regulates the mesenchymal stem cell and osteoclast lineage populations.

Shahnazari M, Chu V, Wronski TJ, Nissenson RA, Halloran BP.

FASEB J. 2013 Sep;27(9):3505-13. doi: 10.1096/fj.12-225763. Epub 2013 May 23.

PMID:
23704087
11.

Increased bone mass in mice lacking the adipokine apelin.

Wattanachanya L, Lu WD, Kundu RK, Wang L, Abbott MJ, O'Carroll D, Quertermous T, Nissenson RA.

Endocrinology. 2013 Jun;154(6):2069-80. doi: 10.1210/en.2012-2034. Epub 2013 Apr 12.

12.

Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor.

Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC.

Calcif Tissue Int. 2011 Jul;89(1):10-20. doi: 10.1007/s00223-011-9487-z. Epub 2011 Apr 28.

13.

Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation.

Millard SM, Louie AM, Wattanachanya L, Wronski TJ, Conklin BR, Nissenson RA.

J Bone Miner Res. 2011 Apr;26(4):822-32. doi: 10.1002/jbmr.273.

14.

Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation.

Hsiao EC, Boudignon BM, Halloran BP, Nissenson RA, Conklin BR.

J Bone Miner Res. 2010 Mar;25(3):584-93. doi: 10.1002/jbmr.3.

15.

Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation.

Hsiao EC, Millard SM, Louie A, Huang Y, Conklin BR, Nissenson RA.

Mol Endocrinol. 2010 Mar;24(3):621-31. doi: 10.1210/me.2009-0424. Epub 2010 Feb 11.

16.

Engineering GPCR signaling pathways with RASSLs.

Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL.

Nat Methods. 2008 Aug;5(8):673-8. doi: 10.1038/nmeth.1232. Review.

17.

Resolution dependence of the non-metric trabecular structure indices.

Sode M, Burghardt AJ, Nissenson RA, Majumdar S.

Bone. 2008 Apr;42(4):728-36. doi: 10.1016/j.bone.2007.12.004. Epub 2007 Dec 23.

18.

Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass.

Hsiao EC, Boudignon BM, Chang WC, Bencsik M, Peng J, Nguyen TD, Manalac C, Halloran BP, Conklin BR, Nissenson RA.

Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1209-14. doi: 10.1073/pnas.0707457105. Epub 2008 Jan 22.

19.

Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia.

Peng J, Bencsik M, Louie A, Lu W, Millard S, Nguyen P, Burghardt A, Majumdar S, Wronski TJ, Halloran B, Conklin BR, Nissenson RA.

Endocrinology. 2008 Mar;149(3):1329-37. Epub 2007 Nov 29.

20.

Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy.

McCloskey DT, Turcato S, Wang GY, Turnbull L, Zhu BQ, Bambino T, Nguyen AP, Lovett DH, Nissenson RA, Karliner JS, Baker AJ.

Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H205-12. Epub 2007 Oct 26.

21.

PTH differentially regulates expression of RANKL and OPG.

Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD, Nissenson RA.

J Bone Miner Res. 2004 Feb;19(2):235-44. Epub 2003 Dec 16.

22.

Parathyroid hormone receptor recycling: role of receptor dephosphorylation and beta-arrestin.

Chauvin S, Bencsik M, Bambino T, Nissenson RA.

Mol Endocrinol. 2002 Dec;16(12):2720-32.

PMID:
12456793
23.

Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association.

Vilardaga JP, Krasel C, Chauvin S, Bambino T, Lohse MJ, Nissenson RA.

J Biol Chem. 2002 Mar 8;277(10):8121-9. Epub 2001 Nov 28.

24.

Parathyroid hormone-related protein.

Nissenson RA.

Rev Endocr Metab Disord. 2000 Nov;1(4):343-52. Review. No abstract available.

PMID:
11706748
27.
28.

Apoptosis mediated by activation of the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein (PTHrP).

Turner PR, Mefford S, Christakos S, Nissenson RA.

Mol Endocrinol. 2000 Feb;14(2):241-54.

PMID:
10674397
29.

Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation.

Sheikh SP, Vilardarga JP, Baranski TJ, Lichtarge O, Iiri T, Meng EC, Nissenson RA, Bourne HR.

J Biol Chem. 1999 Jun 11;274(24):17033-41.

30.

Role of signal transduction in internalization of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein.

Huang Z, Bambino T, Chen Y, Lameh J, Nissenson RA.

Endocrinology. 1999 Mar;140(3):1294-300.

PMID:
10067856
32.

Parathyroid hormone (PTH)/PTHrP receptor mutations in human chondrodysplasia.

Nissenson RA.

Endocrinology. 1998 Dec;139(12):4753-5. Review. No abstract available.

PMID:
9832410
33.
36.

Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development.

Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV.

Endocrinology. 1996 Nov;137(11):5109-18.

PMID:
8895385
37.

Expression of alternatively spliced isoforms of the parathyroid hormone (PTH)/PTH-related peptide receptor messenger RNA in human kidney and bone cells.

Jobert AS, Fernandes I, Turner G, Coureau C, Prie D, Nissenson RA, Friedlander G, Silve C.

Mol Endocrinol. 1996 Sep;10(9):1066-76.

PMID:
8885241
38.

Bone-selective analogs of human PTH(1-34) increase bone formation in an ovariectomized rat model.

Lane NE, Kimmel DB, Nilsson MH, Cohen FE, Newton S, Nissenson RA, Strewler GJ.

J Bone Miner Res. 1996 May;11(5):614-25.

PMID:
9157776
39.

Phosphorylation of the cytoplasmic tail of the PTH/PTHrP receptor.

Blind E, Bambino T, Huang Z, Bliziotes M, Nissenson RA.

J Bone Miner Res. 1996 May;11(5):578-86.

PMID:
9157772
40.

A putative selectivity filter in the G-protein-coupled receptors for parathyroid hormone and secretion.

Turner PR, Bambino T, Nissenson RA.

J Biol Chem. 1996 Apr 19;271(16):9205-8.

41.
42.
43.
44.

Endotoxin induces parathyroid hormone-related protein gene expression in splenic stromal and smooth muscle cells, not in splenic lymphocytes.

Funk JL, Lausier J, Moser AH, Shigenaga JK, Huling S, Nissenson RA, Strewler GJ, Grunfeld C, Feingold KR.

Endocrinology. 1995 Aug;136(8):3412-21.

PMID:
7628377
46.

Functional properties of a synthetic chicken parathyroid hormone-related protein 1-36 fragment.

Schermer DT, Bradley MS, Bambino TH, Nissenson RA, Strewler GJ.

J Bone Miner Res. 1994 Jul;9(7):1041-6.

PMID:
7942150
48.

Production of parathyroid hormone by a malignant nonparathyroid tumor in a hypercalcemic patient.

Strewler GJ, Budayr AA, Clark OH, Nissenson RA.

J Clin Endocrinol Metab. 1993 May;76(5):1373-5.

PMID:
7684395
49.

Structure and function of the receptor for parathyroid hormone and parathyroid hormone-related protein.

Nissenson RA, Huang Z, Blind E, Shoback D.

Receptor. 1993 Fall;3(3):193-202. Review.

PMID:
8167570
50.

Actions of parathyroid hormone-related protein as an embryonic differentiation factor.

Strewler GJ, Chan SD, Globus RK, Schermer DT, Nissenson RA.

J Endocrinol Invest. 1992;15(9 Suppl 6):57-62. Review. No abstract available.

PMID:
1300340

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