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Items: 1 to 50 of 323

1.

Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions.

Saleh N, Wang Y, Nissen P, Lindorff-Larsen K.

Phys Chem Chem Phys. 2019 Oct 9;21(39):21991-21995. doi: 10.1039/c9cp04736k.

PMID:
31552962
2.

Expanding the spectrum of genetic variants in the calcium-sensing receptor (CASR) gene in hypercalcemic individuals.

Nissen PH, Rejnmark L.

Clin Endocrinol (Oxf). 2019 Nov;91(5):683-690. doi: 10.1111/cen.14078. Epub 2019 Sep 9.

PMID:
31433865
3.

Namdinator - automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps.

Kidmose RT, Juhl J, Nissen P, Boesen T, Karlsen JL, Pedersen BP.

IUCrJ. 2019 Jun 27;6(Pt 4):526-531. doi: 10.1107/S2052252519007619. eCollection 2019 Jul 1.

4.

Structure and autoregulation of a P4-ATPase lipid flippase.

Timcenko M, Lyons JA, Januliene D, Ulstrup JJ, Dieudonné T, Montigny C, Ash MR, Karlsen JL, Boesen T, Kühlbrandt W, Lenoir G, Moeller A, Nissen P.

Nature. 2019 Jul;571(7765):366-370. doi: 10.1038/s41586-019-1344-7. Epub 2019 Jun 26.

PMID:
31243363
5.

Platelet microRNA expression and association with platelet maturity and function in patients with essential thrombocythemia.

Tran JQD, Pedersen OH, Larsen ML, Grove EL, Kristensen SD, Hvas AM, Nissen PH.

Platelets. 2019 Jun 26:1-8. doi: 10.1080/09537104.2019.1636019. [Epub ahead of print]

PMID:
31240987
6.

Whole blood platelet aggregation determined by the ROTEM platelet equipment; reference intervals and stability.

Nissen PH, Skipper MT, Hvas AM.

Platelets. 2019 Apr 1:1-6. doi: 10.1080/09537104.2019.1595562. [Epub ahead of print]

PMID:
30935283
7.

Fast spin exchange across a multielectron mediator.

Malinowski FK, Martins F, Smith TB, Bartlett SD, Doherty AC, Nissen PD, Fallahi S, Gardner GC, Manfra MJ, Marcus CM, Kuemmeth F.

Nat Commun. 2019 Mar 13;10(1):1196. doi: 10.1038/s41467-019-09194-x.

8.

Structures of the heart specific SERCA2a Ca2+-ATPase.

Sitsel A, De Raeymaecker J, Drachmann ND, Derua R, Smaardijk S, Andersen JL, Vandecaetsbeek I, Chen J, De Maeyer M, Waelkens E, Olesen C, Vangheluwe P, Nissen P.

EMBO J. 2019 Mar 1;38(5). pii: e100020. doi: 10.15252/embj.2018100020. Epub 2019 Feb 18.

PMID:
30777856
9.

SERPINC1 variants causing hereditary antithrombin deficiency in a Danish population.

Kjaergaard AD, Larsen OH, Hvas AM, Nissen PH.

Thromb Res. 2019 Mar;175:68-75. doi: 10.1016/j.thromres.2019.01.022. Epub 2019 Jan 31.

PMID:
30721820
10.

Membrane-protein crystals for neutron diffraction.

Sørensen TLM, Hjorth-Jensen SJ, Oksanen E, Andersen JL, Olesen C, Møller JV, Nissen P.

Acta Crystallogr D Struct Biol. 2018 Dec 1;74(Pt 12):1208-1218. doi: 10.1107/S2059798318012561. Epub 2018 Nov 30.

PMID:
30605135
11.

Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases.

Andersen JL, Gesser B, Funder ED, Nielsen CJF, Gotfred-Rasmussen H, Rasmussen MK, Toth R, Gothelf KV, Arthur JSC, Iversen L, Nissen P.

Nat Commun. 2018 Oct 19;9(1):4344. doi: 10.1038/s41467-018-06787-w.

12.

Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death.

Szalai P, Parys JB, Bultynck G, Christensen SB, Nissen P, Møller JV, Engedal N.

Cell Calcium. 2018 Dec;76:48-61. doi: 10.1016/j.ceca.2018.09.005. Epub 2018 Sep 17.

PMID:
30261424
13.

Jens Christian Skou (1918-2018).

Nissen P.

Science. 2018 Jul 13;361(6398):133. doi: 10.1126/science.aau5275. No abstract available.

PMID:
30002243
14.

The clinical outcome of LMNA missense mutations can be associated with the amount of mutated protein in the nuclear envelope.

Al-Saaidi RA, Rasmussen TB, Birkler RID, Palmfeldt J, Beqqali A, Pinto YM, Nissen PH, Baandrup U, Mølgaard H, Hey TM, Eiskjaer H, Bross P, Mogensen J.

Eur J Heart Fail. 2018 Oct;20(10):1404-1412. doi: 10.1002/ejhf.1241. Epub 2018 Jun 26.

15.

Interactions of a Bacterial Cu(I)-ATPase with a Complex Lipid Environment.

Autzen HE, Koldsø H, Stansfeld PJ, Gourdon P, Sansom MSP, Nissen P.

Biochemistry. 2018 Jul 17;57(28):4063-4073. doi: 10.1021/acs.biochem.8b00326. Epub 2018 Jun 27.

PMID:
29894640
16.

Platelet characteristics in patients with essential thrombocytosis.

Pedersen OH, Larsen ML, Grove EL, van Kooten Niekerk PB, Bønløkke S, Nissen PH, Kristensen SD, Hvas AM.

Cytometry B Clin Cytom. 2018 Nov;94(6):918-927. doi: 10.1002/cyto.b.21642. Epub 2018 Sep 3.

PMID:
29790256
17.

Pro-FHH: A Risk Equation to Facilitate the Diagnosis of Parathyroid-Related Hypercalcemia.

Bertocchio JP, Tafflet M, Koumakis E, Maruani G, Vargas-Poussou R, Silve C, Nissen PH, Baron S, Prot-Bertoye C, Courbebaisse M, Souberbielle JC, Rejnmark L, Cormier C, Houillier P.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2534-2542. doi: 10.1210/jc.2017-02773.

PMID:
29727008
18.

Lactase persistence genotyping on whole blood by loop-mediated isothermal amplification and melting curve analysis.

Abildgaard A, Tovbjerg SK, Giltay A, Detemmerman L, Nissen PH.

Clin Chim Acta. 2018 Jul;482:50-56. doi: 10.1016/j.cca.2018.03.029. Epub 2018 Mar 26.

PMID:
29596814
19.

Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs.

Chen M, Laursen SH, Habekost M, Knudsen CH, Buchholdt SH, Huang J, Xu F, Liu X, Bolund L, Luo Y, Nissen P, Febbraro F, Denham M.

Front Cell Dev Biol. 2018 Feb 6;6:5. doi: 10.3389/fcell.2018.00005. eCollection 2018.

20.

A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin-biased signaling.

Gorvin CM, Babinsky VN, Malinauskas T, Nissen PH, Schou AJ, Hanyaloglu AC, Siebold C, Jones EY, Hannan FM, Thakker RV.

Sci Signal. 2018 Feb 20;11(518). pii: eaan3714. doi: 10.1126/scisignal.aan3714.

21.

The impact of pneumatic tube transport on whole blood coagulation and platelet function assays.

Nissen PH, Wulff DE, Tørring N, Hvas AM.

Platelets. 2018 Jun;29(4):421-424. doi: 10.1080/09537104.2018.1430361. Epub 2018 Feb 14.

PMID:
29442531
22.

Negative Spin Exchange in a Multielectron Quantum Dot.

Martins F, Malinowski FK, Nissen PD, Fallahi S, Gardner GC, Manfra MJ, Marcus CM, Kuemmeth F.

Phys Rev Lett. 2017 Dec 1;119(22):227701. doi: 10.1103/PhysRevLett.119.227701. Epub 2017 Nov 30.

PMID:
29286778
23.

Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.

Midtgaard SR, Darwish TA, Pedersen MC, Huda P, Larsen AH, Jensen GV, Kynde SAR, Skar-Gislinge N, Nielsen AJZ, Olesen C, Blaise M, Dorosz JJ, Thorsen TS, Venskutonytė R, Krintel C, Møller JV, Frielinghaus H, Gilbert EP, Martel A, Kastrup JS, Jensen PE, Nissen P, Arleth L.

FEBS J. 2018 Jan;285(2):357-371. doi: 10.1111/febs.14345. Epub 2017 Dec 30.

24.

Dynamics of P-type ATPase transport revealed by single-molecule FRET.

Dyla M, Terry DS, Kjaergaard M, Sørensen TL, Lauwring Andersen J, Andersen JP, Rohde Knudsen C, Altman RB, Nissen P, Blanchard SC.

Nature. 2017 Nov 16;551(7680):346-351. doi: 10.1038/nature24296. Epub 2017 Nov 8.

25.

Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response.

Sehgal P, Szalai P, Olesen C, Praetorius HA, Nissen P, Christensen SB, Engedal N, Møller JV.

J Biol Chem. 2017 Dec 1;292(48):19656-19673. doi: 10.1074/jbc.M117.796920. Epub 2017 Sep 29.

26.

Platelet function investigation by flow cytometry: Sample volume, needle size, and reference intervals.

Pedersen OH, Nissen PH, Hvas AM.

Platelets. 2018 Mar;29(2):199-202. doi: 10.1080/09537104.2017.1353684. Epub 2017 Sep 29.

PMID:
28960147
27.

Saposin-Lipoprotein Scaffolds for Structure Determination of Membrane Transporters.

Lyons JA, Bøggild A, Nissen P, Frauenfeld J.

Methods Enzymol. 2017;594:85-99. doi: 10.1016/bs.mie.2017.06.035. Epub 2017 Jul 19.

PMID:
28779844
28.

Long-term Outcome of 4 Patients With Transcobalamin Deficiency Caused by 2 Novel TCN2 Mutations.

Nashabat M, Maegawa G, Nissen PH, Nexo E, Al-Shamrani H, Al-Owain M, Alfadhel M.

J Pediatr Hematol Oncol. 2017 Nov;39(8):e430-e436. doi: 10.1097/MPH.0000000000000857.

PMID:
28538514
29.

Spectrum of the Nuclear Environment for GaAs Spin Qubits.

Malinowski FK, Martins F, Cywiński Ł, Rudner MS, Nissen PD, Fallahi S, Gardner GC, Manfra MJ, Marcus CM, Kuemmeth F.

Phys Rev Lett. 2017 Apr 28;118(17):177702. doi: 10.1103/PhysRevLett.118.177702. Epub 2017 Apr 28.

PMID:
28498694
30.
31.

Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease.

Skjørringe T, Amstrup Pedersen P, Salling Thorborg S, Nissen P, Gourdon P, Birk Møller L.

Sci Rep. 2017 Apr 7;7(1):757. doi: 10.1038/s41598-017-00618-6.

32.

The role of transmembrane segment 5 (TM5) in Na2 release and the conformational transition of neurotransmitter:sodium symporters toward the inward-open state.

Stolzenberg S, Li Z, Quick M, Malinauskaite L, Nissen P, Weinstein H, Javitch JA, Shi L.

J Biol Chem. 2017 May 5;292(18):7372-7384. doi: 10.1074/jbc.M116.757153. Epub 2017 Mar 20.

33.

High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N- and C-terminal extensions.

Azouaoui H, Montigny C, Dieudonné T, Champeil P, Jacquot A, Vázquez-Ibar JL, Le Maréchal P, Ulstrup J, Ash MR, Lyons JA, Nissen P, Lenoir G.

J Biol Chem. 2017 May 12;292(19):7954-7970. doi: 10.1074/jbc.M116.751487. Epub 2017 Mar 16.

34.

Brief encounters of cytochrome c.

Lyons JA, Nissen P.

EMBO J. 2017 Feb 1;36(3):250-251. doi: 10.15252/embj.201696124. Epub 2017 Jan 13. No abstract available.

35.

AP2S1 and GNA11 mutations - not a common cause of familial hypocalciuric hypercalcemia.

Hovden S, Rejnmark L, Ladefoged SA, Nissen PH.

Eur J Endocrinol. 2017 Feb;176(2):177-185. Epub 2016 Nov 15.

PMID:
27913609
36.

Stability of direct oral anticoagulants in whole blood and plasma from patients in steady state treatment.

McGrail R, Revsholm J, Nissen PH, Grove EL, Hvas AM.

Thromb Res. 2016 Dec;148:107-110. doi: 10.1016/j.thromres.2016.10.023. Epub 2016 Oct 27.

PMID:
27835819
37.

Notch filtering the nuclear environment of a spin qubit.

Malinowski FK, Martins F, Nissen PD, Barnes E, Cywiński Ł, Rudner MS, Fallahi S, Gardner GC, Manfra MJ, Marcus CM, Kuemmeth F.

Nat Nanotechnol. 2017 Jan;12(1):16-20. doi: 10.1038/nnano.2016.170. Epub 2016 Oct 3.

PMID:
27694847
38.

Multiple endocrine neoplasia phenocopy revealed as a co-occurring neuroendocrine tumor and familial hypocalciuric hypercalcemia type 3.

Hovden S, Jespersen ML, Nissen PH, Poulsen PL, Rolighed L, Ladefoged SA, Rejnmark L.

Clin Case Rep. 2016 Aug 18;4(10):922-927. eCollection 2016 Oct.

39.

Cognitive deficits caused by a disease-mutation in the α3 Na(+)/K(+)-ATPase isoform.

Holm TH, Isaksen TJ, Glerup S, Heuck A, Bøttger P, Füchtbauer EM, Nedergaard S, Nyengaard JR, Andreasen M, Nissen P, Lykke-Hartmann K.

Sci Rep. 2016 Aug 23;6:31972. doi: 10.1038/srep31972.

40.

Engineering a Prototypic P-type ATPase Listeria monocytogenes Ca(2+)-ATPase 1 for Single-Molecule FRET Studies.

Dyla M, Andersen JL, Kjaergaard M, Birkedal V, Terry DS, Altman RB, Blanchard SC, Nissen P, Knudsen CR.

Bioconjug Chem. 2016 Sep 21;27(9):2176-87. doi: 10.1021/acs.bioconjchem.6b00387. Epub 2016 Aug 24.

41.

The cardiovascular system in familial hypocalciuric hypercalcemia: a cross-sectional study on physiological effects of inactivating variants in the calcium-sensing receptor gene.

Breum Jakobsen NF, Laugesen E, Rolighed L, Nissen PH, Poulsen PL, Pedersen EB, Mosekilde L, Rejnmark L.

Eur J Endocrinol. 2016 Oct;175(4):299-309. doi: 10.1530/EJE-16-0369. Epub 2016 Jul 14.

PMID:
27418061
42.

Expression strategies for structural studies of eukaryotic membrane proteins.

Lyons JA, Shahsavar A, Paulsen PA, Pedersen BP, Nissen P.

Curr Opin Struct Biol. 2016 Jun;38:137-44. doi: 10.1016/j.sbi.2016.06.011. Epub 2016 Jun 27. Review.

PMID:
27362979
43.

A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.

Malinauskaite L, Said S, Sahin C, Grouleff J, Shahsavar A, Bjerregaard H, Noer P, Severinsen K, Boesen T, Schiøtt B, Sinning S, Nissen P.

Nat Commun. 2016 May 25;7:11673. doi: 10.1038/ncomms11673.

44.

False low holotranscobalamin levels in a patient with a novel TCN2 mutation.

Keller P, Rufener J, Schild C, Fedosov SN, Nissen PH, Nexo E.

Clin Chem Lab Med. 2016 Nov 1;54(11):1739-1743. doi: 10.1515/cclm-2016-0063.

45.

Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase.

Clausen JD, Bublitz M, Arnou B, Olesen C, Andersen JP, Møller JV, Nissen P.

Structure. 2016 Apr 5;24(4):617-623. doi: 10.1016/j.str.2016.02.018.

46.

Isolation, crystallization and crystal structure determination of bovine kidney Na(+),K(+)-ATPase.

Gregersen JL, Mattle D, Fedosova NU, Nissen P, Reinhard L.

Acta Crystallogr F Struct Biol Commun. 2016 Apr;72(Pt 4):282-7. doi: 10.1107/S2053230X1600279X. Epub 2016 Mar 16.

47.

Erratum: Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes.

David-Bosne S, Clausen MV, Poulsen H, Møller JV, Nissen P, le Maire M.

Nat Struct Mol Biol. 2016 Apr;23(4):358. doi: 10.1038/nsmb0416-358a. No abstract available.

PMID:
27045446
48.

Noise Suppression Using Symmetric Exchange Gates in Spin Qubits.

Martins F, Malinowski FK, Nissen PD, Barnes E, Fallahi S, Gardner GC, Manfra MJ, Marcus CM, Kuemmeth F.

Phys Rev Lett. 2016 Mar 18;116(11):116801. doi: 10.1103/PhysRevLett.116.116801. Epub 2016 Mar 16.

PMID:
27035316
49.

Crystal Structure of an Ammonia-Permeable Aquaporin.

Kirscht A, Kaptan SS, Bienert GP, Chaumont F, Nissen P, de Groot BL, Kjellbom P, Gourdon P, Johanson U.

PLoS Biol. 2016 Mar 30;14(3):e1002411. doi: 10.1371/journal.pbio.1002411. eCollection 2016 Mar.

50.

Initiating heavy-atom-based phasing by multi-dimensional molecular replacement.

Pedersen BP, Gourdon P, Liu X, Karlsen JL, Nissen P.

Acta Crystallogr D Struct Biol. 2016 Mar;72(Pt 3):440-5. doi: 10.1107/S2059798315022482. Epub 2016 Mar 1.

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