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Items: 1 to 50 of 107

1.

Effect of inter-individual variability in human liver cytochrome P450 isozymes on cyclophosphamide-induced micronucleus formation.

Kishino Y, Hasegawa T, Kato A, Nishiya Y, Rozhnal V, Watanabe K, Takasaki W, Yamoto T, Mori K.

Mutat Res. 2019 Feb;838:37-45. doi: 10.1016/j.mrgentox.2018.11.016. Epub 2018 Dec 5.

PMID:
30678826
2.

Acantholytic Squamous Cell Carcinoma and Salivary Duct Carcinoma Ex-pleomorphic Adenoma of the Submandibular Gland: A Report of Two Extremely Rare Cases with an Immunohistochemical Analysis.

Kusafuka K, Kawasaki T, Onitsuka T, Hamaguchi N, Morita K, Mukaigawa T, Nishiya Y, Kamijo T, Iida Y, Nakajima T, Sugino T.

Head Neck Pathol. 2018 Nov 27. doi: 10.1007/s12105-018-0987-2. [Epub ahead of print]

PMID:
30484070
3.

Depth of invasion in superficial oral tongue carcinoma quantified using intraoral ultrasonography.

Iida Y, Kamijo T, Kusafuka K, Omae K, Nishiya Y, Hamaguchi N, Morita K, Onitsuka T.

Laryngoscope. 2018 Dec;128(12):2778-2782. doi: 10.1002/lary.27305. Epub 2018 Oct 16.

PMID:
30325049
4.

Characterization of d-succinylase from Cupriavidus sp. P4-10-C and its application in d-amino acid synthesis.

Sumida Y, Iwai S, Nishiya Y, Kumagai S, Yamada T, Azuma M.

J Biosci Bioeng. 2018 Mar;125(3):282-286. doi: 10.1016/j.jbiosc.2017.10.007. Epub 2017 Nov 15.

PMID:
29153699
5.

Over-expression, characterization, and modification of highly active alkaline phosphatase from a Shewanella genus bacterium.

Aiba H, Nishiya Y, Ojima Y, Azuma M.

Biosci Biotechnol Biochem. 2017 Oct;81(10):1994-2001. doi: 10.1080/09168451.2017.1356217. Epub 2017 Jul 31.

PMID:
28756743
6.

The reaction mechanism of sarcosine oxidase elucidated using FMO and QM/MM methods.

Abe Y, Shoji M, Nishiya Y, Aiba H, Kishimoto T, Kitaura K.

Phys Chem Chem Phys. 2017 Apr 12;19(15):9811-9822. doi: 10.1039/c6cp08172j.

PMID:
28374027
7.

A new efficient method of generating photoaffinity beads for drug target identification.

Nishiya Y, Hamada T, Abe M, Takashima M, Tsutsumi K, Okawa K.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):834-840. doi: 10.1016/j.bmcl.2017.01.021. Epub 2017 Jan 10.

PMID:
28108248
8.

Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib.

Nishiya Y, Nakai D, Urasaki Y, Takakusa H, Ohsuki S, Iwano Y, Yasukochi T, Takayama T, Bazyo S, Oza C, Kurihara A, Savage RE, Izumi T.

Xenobiotica. 2016 Nov;46(11):967-76. doi: 10.3109/00498254.2016.1144896. Epub 2016 Feb 22.

PMID:
26899628
9.

Hyperstabilization of Tetrameric Bacillus sp. TB-90 Urate Oxidase by Introducing Disulfide Bonds through Structural Plasticity.

Hibi T, Kume A, Kawamura A, Itoh T, Fukada H, Nishiya Y.

Biochemistry. 2016 Feb 2;55(4):724-32. doi: 10.1021/acs.biochem.5b01119. Epub 2016 Jan 15.

PMID:
26739254
10.

Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin.

Sawamura R, Sakurai H, Wada N, Nishiya Y, Honda T, Kazui M, Kurihara A, Shinagawa A, Izumi T.

Biopharm Drug Dispos. 2015 Sep;36(6):352-363. doi: 10.1002/bdd.1945. Epub 2015 Apr 21.

PMID:
25765700
11.

Characterization of a thermostable glucose dehydrogenase with strict substrate specificity from a hyperthermophilic archaeon Thermoproteus sp. GDH-1.

Aiba H, Nishiya Y, Azuma M, Yokooji Y, Atomi H, Imanaka T.

Biosci Biotechnol Biochem. 2015;79(7):1094-102. doi: 10.1080/09168451.2015.1018120. Epub 2015 Mar 9.

PMID:
25746627
12.

Simple and reliable urea assay based on a signal accumulation type of ion-sensitive field-effect transistor.

Tomari N, Kawasaki A, Yamamoto Y, Nishiya Y.

J Biosci Bioeng. 2015 Feb;119(2):247-50. doi: 10.1016/j.jbiosc.2014.07.011. Epub 2014 Sep 2.

PMID:
25193874
13.

Intersubunit salt bridges with a sulfate anion control subunit dissociation and thermal stabilization of Bacillus sp. TB-90 urate oxidase.

Hibi T, Hayashi Y, Fukada H, Itoh T, Nago T, Nishiya Y.

Biochemistry. 2014 Jun 24;53(24):3879-888. Erratum in: Biochemistry. 2014 Aug 26;53(33):5471.

PMID:
24897238
14.

The anti-overactive bladder activity of KW-7158 is mediated by blocking equilibrative nucleoside transporter-1.

Nishiya Y, Yamagata T, Fukuda A, Yokokawa S, Seishi T, Sakuma T, Sasho S, Shimizu Y, Sato H, Sekine S, Kamigaki M, Yoshida T, Shibata K.

Biol Pharm Bull. 2014;37(1):130-6. Epub 2013 Oct 26.

15.

Structure-guided mutagenesis for the improvement of substrate specificity of Bacillus megaterium glucose 1-dehydrogenase IV.

Nishioka T, Yasutake Y, Nishiya Y, Tamura T.

FEBS J. 2012 Sep;279(17):3264-75. doi: 10.1111/j.1742-4658.2012.08713.x. Epub 2012 Aug 17.

16.

[Cardiac angiosarcoma resected after definitive diagnosis by thoracoscope-assisted biopsy].

Ueda T, Sotokawa M, Tateishi M, Hoshino S, Nishiya Y, Miyazawa H, Shinnou H, Nakata A.

Kyobu Geka. 2012 Jun;65(6):484-7. Japanese.

PMID:
22647332
17.

The generation of rat dorsal root ganglion cell lines to identify the target of KW-7158, a novel treatment for overactive bladder.

Nishiya Y, Yokokawa S, Fukuda A, Yamagata T, Inayoshi A, Obinata M, Shibata K.

Neurosci Res. 2011 Nov;71(3):278-88. doi: 10.1016/j.neures.2011.07.1823. Epub 2011 Jul 23.

PMID:
21802454
18.

Insertion sequence-excision enhancer removes transposable elements from bacterial genomes and induces various genomic deletions.

Kusumoto M, Ooka T, Nishiya Y, Ogura Y, Saito T, Sekine Y, Iwata T, Akiba M, Hayashi T.

Nat Commun. 2011 Jan 11;2:152.

PMID:
21224843
19.

Rupture of Kommerell diverticulum after total arch replacement.

Agematsu K, Ueda T, Hoshino S, Nishiya Y.

Interact Cardiovasc Thorac Surg. 2010 Dec;11(6):800-2. doi: 10.1510/icvts.2010.241802. Epub 2010 Sep 9.

PMID:
20829386
20.

Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase.

Yamashita K, Nakajima Y, Matsushita H, Nishiya Y, Yamazawa R, Wu YF, Matsubara F, Oyama H, Ito K, Yoshimoto T.

J Mol Biol. 2010 Mar 5;396(4):1081-96. doi: 10.1016/j.jmb.2009.12.045. Epub 2010 Jan 4.

PMID:
20043918
21.

Effects of organic solvents on the time-dependent inhibition of CYP3A4 by diazepam.

Nishiya Y, Nakamura K, Okudaira N, Abe K, Kobayashi N, Okazaki O.

Xenobiotica. 2010 Jan;40(1):1-8. doi: 10.3109/00498250903337392.

PMID:
19905875
22.

Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel.

Nishiya Y, Hagihara K, Kurihara A, Okudaira N, Farid NA, Okazaki O, Ikeda T.

Xenobiotica. 2009 Nov;39(11):836-43. doi: 10.3109/00498250903191427.

PMID:
19845434
23.

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.

Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A.

Drug Metab Dispos. 2010 Jan;38(1):92-9. doi: 10.1124/dmd.109.029132.

PMID:
19812348
24.

Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, clopidogrel, and ticlopidine.

Hagihara K, Nishiya Y, Kurihara A, Kazui M, Farid NA, Ikeda T.

Drug Metab Pharmacokinet. 2008;23(6):412-20.

25.

Drug-target identification from total cellular lysate by drug-induced conformational changes.

Nishiya Y, Shibata K, Saito S, Yano K, Oneyama C, Nakano H, Sharma SV.

Anal Biochem. 2009 Feb 15;385(2):314-20. doi: 10.1016/j.ab.2008.11.034. Epub 2008 Dec 6.

PMID:
19103144
26.

C-terminal tail derived from the neighboring subunit is critical for the activity of Thermoplasma acidophilum D-aldohexose dehydrogenase.

Nishioka T, Yasutake Y, Nishiya Y, Tamura N, Tamura T.

Proteins. 2009 Mar;74(4):801-7. doi: 10.1002/prot.22300.

PMID:
19089950
27.

[Huge right atrial myxoma].

Sotokawa M, Nishiya Y, Hoshino S, Ueda T, Saitou N, Murata A, Yusa H, Tateishi M, Usuda K, Nagata Y, Miwa A, Uchiyama A.

Kyobu Geka. 2008 Nov;61(12):1035-8. Japanese.

PMID:
19048903
28.

Mechanism-based inhibition of human cytochrome P450 2B6 by ticlopidine, clopidogrel, and the thiolactone metabolite of prasugrel.

Nishiya Y, Hagihara K, Ito T, Tajima M, Miura S, Kurihara A, Farid NA, Ikeda T.

Drug Metab Dispos. 2009 Mar;37(3):589-93. doi: 10.1124/dmd.108.022988. Epub 2008 Dec 1.

PMID:
19047469
29.

Structural insights into unique substrate selectivity of Thermoplasma acidophilum D-aldohexose dehydrogenase.

Yasutake Y, Nishiya Y, Tamura N, Tamura T.

J Mol Biol. 2007 Apr 6;367(4):1034-46. Epub 2007 Jan 16.

PMID:
17300803
30.

Characterization of a NADH:dichloroindophenol oxidoreductase from Bacillus subtilis.

Nishiya Y, Yamamoto Y.

Biosci Biotechnol Biochem. 2007 Feb;71(2):611-4. Epub 2007 Feb 7.

31.

Crystallization and preliminary crystallographic analysis of NAD+-preferring aldohexose dehydrogenase from the thermoacidophilic archaeon Thermoplasma acidophilum.

Yasutake Y, Nishiya Y, Tamura N, Tamura T.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):586-9. Epub 2006 May 31.

32.
33.

[Abdominal aortic aneurysm with chronic contained rupture in a ninety-year-old woman: a case report].

Saito N, Nishiya Y, Sotokawa M, Yusa H, Murata A, Hoshino S.

J Cardiol. 2006 Feb;47(2):95-8. Japanese.

PMID:
16515360
34.

[Double outlet right ventricle and pulmonary atresia with a birth weight of 1092 g].

Murata A, Hoshino S, Yusa H, Saito N, Nishiya Y, Hatasaki K.

Kyobu Geka. 2005 Dec;58(13):1117-20. Japanese.

PMID:
16359008
35.

Homogeneous enzymatic assay for L-cysteine with betaC-S lyase.

Nishiya Y, Yoshida Y, Yoshimura M, Fukamachi H, Nakano Y.

Biosci Biotechnol Biochem. 2005 Nov;69(11):2244-6.

36.

[Severe tracheal compression resulting from atherosclerotic aortic arch aneurysm; report of a case].

Yusa H, Nishiya Y, Murata A, Konuma T, Saito N, Hoshino S.

Kyobu Geka. 2005 Nov;58(12):1077-80. Japanese.

PMID:
16281860
37.

Host-dependent activation of IS1203v excision in Shiga toxin-producing Escherichia coli.

Kusumoto M, Suzuki R, Nishiya Y, Okitsu T, Oka M.

J Biosci Bioeng. 2004;97(6):406-11.

PMID:
16233651
38.

Spontaneous reactivation of Shiga toxins in Escherichia coli O157:H7 cells caused by transposon excision.

Kusumoto M, Okitsu T, Nishiya Y, Suzuki R, Yamai S, Kawamura Y.

J Biosci Bioeng. 2001;92(2):114-20.

PMID:
16233069
39.

Identification of an insertion sequence, IS1203 variant, in a Shiga toxin 2 gene of Escherichia coli O157:H7.

Kusumoto M, Nishiya Y, Kawamura Y, Shinagawa K.

J Biosci Bioeng. 1999;87(1):93-6.

PMID:
16232431
40.

[De Bakey type I aortic dissection complicating systemic lupus erythematosus; report of a case].

Murata A, Nishiya Y, Saito N, Konuma T, Yusa H, Hoshino S.

Kyobu Geka. 2005 Sep;58(10):902-5. Japanese.

PMID:
16167818
41.

Detection and quantification of on-chip phosphorylated peptides by surface plasmon resonance imaging techniques using a phosphate capture molecule.

Inamori K, Kyo M, Nishiya Y, Inoue Y, Sonoda T, Kinoshita E, Koike T, Katayama Y.

Anal Chem. 2005 Jul 1;77(13):3979-85.

PMID:
15987100
43.

Progressive diffuse aortic stenosis after localized supravalvular aortic stenosis repair.

Kosaka Y, Hoshino S, Azuma T, Nishiya Y.

Jpn J Thorac Cardiovasc Surg. 2003 Dec;51(12):675-7.

PMID:
14717424
44.

Gene cloning and function analysis of replication factor C from Thermococcus kodakaraensis KOD1.

Kitabayashi M, Nishiya Y, Esaka M, Itakura M, Imanaka T.

Biosci Biotechnol Biochem. 2003 Nov;67(11):2373-80.

45.

A simple and eficient method for high fidelity PCR cloning using antibody-neutralizing technology.

Kitabayashi M, Nishiya Y, Esaka M.

Biosci Biotechnol Biochem. 2003 Sep;67(9):2034-7.

46.

Preliminary crystallographic studies of the creatinine amidohydrolase from Pseudomonas putida.

Ito K, Kanada N, Inoue T, Furukawa K, Yamashita K, Tanaka N, Nakamura KT, Nishiya Y, Sogabe A, Yoshimoto T.

Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2180-1. Epub 2002 Nov 23.

PMID:
12454494
47.

Gene cloning and polymerase chain reaction with proliferating cell nuclear antigen from Thermococcus kodakaraensis KOD1.

Kitabayashi M, Nishiya Y, Esaka M, Itakura M, Imanaka T.

Biosci Biotechnol Biochem. 2002 Oct;66(10):2194-200.

48.
49.

Solution structure of an RNA fragment with the P7/P9.0 region and the 3'-terminal guanosine of the tetrahymena group I intron.

Kitamura A, Muto Y, Watanabe S, Kim I, Ito T, Nishiya Y, Sakamoto K, Ohtsuki T, Kawai G, Watanabe K, Hosono K, Takaku H, Katoh E, Yamazaki T, Inoue T, Yokoyama S.

RNA. 2002 Apr;8(4):440-51.

50.

A potent 1,4-dihydropyridine L-type calcium channel blocker, benidipine, promotes osteoblast differentiation.

Nishiya Y, Kosaka N, Uchii M, Sugimoto S.

Calcif Tissue Int. 2002 Jan;70(1):30-9. Epub 2001 Dec 21.

PMID:
11907705

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