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Items: 1 to 50 of 63

1.

Plasma citrulline is a sensitive safety biomarker for small intestinal injury in rats.

Saitoh W, Takada S, Hirao J, Shirai M, Iguchi T, Tsuji M, Nishiya T, Mori K.

Toxicol Lett. 2018 Oct 1;295:416-423. doi: 10.1016/j.toxlet.2018.07.009. Epub 2018 Jul 29.

PMID:
30012503
2.

TRAV7-2*02 Expressing CD8⁺ T Cells Are Responsible for Palladium Allergy.

Takeda Y, Suto Y, Ito K, Hashimoto W, Nishiya T, Ueda K, Narushima T, Takahashi T, Ogasawara K.

Int J Mol Sci. 2017 May 31;18(6). pii: E1162. doi: 10.3390/ijms18061162.

3.

Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development.

Masubuchi N, Nishiya T, Imaoka M, Mizumaki K, Okazaki O.

Chem Biol Interact. 2016 Aug 5;255:74-82. doi: 10.1016/j.cbi.2015.09.012. Epub 2015 Sep 11.

PMID:
26365562
4.

Correlation between attenuation of protein disulfide isomerase activity through S-mercuration and neurotoxicity induced by methylmercury.

Makino K, Okuda K, Sugino E, Nishiya T, Toyama T, Iwawaki T, Fujimura M, Kumagai Y, Uehara T.

Neurotox Res. 2015 Feb;27(2):99-105. doi: 10.1007/s12640-014-9494-8. Epub 2014 Oct 7.

PMID:
25288108
5.

NKG2D⁺ IFN-γ⁺ CD8⁺ T cells are responsible for palladium allergy.

Kawano M, Nakayama M, Aoshima Y, Nakamura K, Ono M, Nishiya T, Nakamura S, Takeda Y, Dobashi A, Takahashi A, Endo M, Ito A, Ueda K, Sato N, Higuchi S, Kondo T, Hashimoto S, Watanabe M, Watanabe M, Takahashi T, Sasaki K, Nakamura M, Sasazuki T, Narushima T, Suzuki R, Ogasawara K.

PLoS One. 2014 Feb 12;9(2):e86810. doi: 10.1371/journal.pone.0086810. eCollection 2014.

6.

Nicotine- and tar-free cigarette smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase.

Asano H, Horinouchi T, Mai Y, Sawada O, Fujii S, Nishiya T, Minami M, Katayama T, Iwanaga T, Terada K, Miwa S.

J Pharmacol Sci. 2012;118(2):275-87. Epub 2012 Feb 3.

7.

Function and regulation of endothelin type A receptor-operated transient receptor potential canonical channels.

Horinouchi T, Terada K, Higa T, Aoyagi H, Nishiya T, Suzuki H, Miwa S.

J Pharmacol Sci. 2011;117(4):295-306. Epub 2011 Dec 1.

8.

Adenylate cyclase/cAMP/protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca²⁺ entry mediated via transient receptor potential canonical 6 channels.

Horinouchi T, Higa T, Aoyagi H, Nishiya T, Terada K, Miwa S.

J Pharmacol Exp Ther. 2012 Jan;340(1):143-51. doi: 10.1124/jpet.111.187500. Epub 2011 Oct 14.

PMID:
22001259
9.

On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN).

Numajiri N, Takasawa K, Nishiya T, Tanaka H, Ohno K, Hayakawa W, Asada M, Matsuda H, Azumi K, Kamata H, Nakamura T, Hara H, Minami M, Lipton SA, Uehara T.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10349-54. doi: 10.1073/pnas.1103503108. Epub 2011 Jun 6.

10.

The ECS(SPSB) E3 ubiquitin ligase is the master regulator of the lifetime of inducible nitric-oxide synthase.

Matsumoto K, Nishiya T, Maekawa S, Horinouchi T, Ogasawara K, Uehara T, Miwa S.

Biochem Biophys Res Commun. 2011 May 27;409(1):46-51. doi: 10.1016/j.bbrc.2011.04.103. Epub 2011 Apr 28.

PMID:
21549100
11.

[Translational research of DDS based on polymeric micelles].

Nishiya T, Matsumura Y, Kataoka K.

Nihon Yakurigaku Zasshi. 2011 Feb;137(2):75-8. doi: 10.1254/fpj.137.75. Review. Japanese. No abstract available.

PMID:
21321455
12.

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours.

Plummer R, Wilson RH, Calvert H, Boddy AV, Griffin M, Sludden J, Tilby MJ, Eatock M, Pearson DG, Ottley CJ, Matsumura Y, Kataoka K, Nishiya T.

Br J Cancer. 2011 Feb 15;104(4):593-8. doi: 10.1038/bjc.2011.6. Epub 2011 Feb 1.

13.

Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins.

Nishiya T, Matsumoto K, Maekawa S, Kajita E, Horinouchi T, Fujimuro M, Ogasawara K, Uehara T, Miwa S.

J Biol Chem. 2011 Mar 18;286(11):9009-19. doi: 10.1074/jbc.M110.190678. Epub 2011 Jan 3.

14.

Screening systems for the identification of S-nitrosylated proteins.

Uehara T, Nishiya T.

Nitric Oxide. 2011 Aug 1;25(2):108-11. doi: 10.1016/j.niox.2010.11.002. Epub 2010 Nov 24. Review.

PMID:
21111056
15.

Endothelin type B receptor-induced sustained Ca2+ influx involves G(q/11)/phospholipase C-independent, p38 mitogen-activated protein kinase-dependent activation of Na+/H+ exchanger.

Higa T, Horinouchi T, Aoyagi H, Asano H, Nishiya T, Nishimoto A, Muramatsu I, Miwa S.

J Pharmacol Sci. 2010;113(3):276-80. Epub 2010 Jun 29.

16.

Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation.

Nishimoto A, Lu L, Hayashi M, Nishiya T, Horinouchi T, Miwa S.

Biochem Biophys Res Commun. 2010 Jan 22;391(4):1616-22. doi: 10.1016/j.bbrc.2009.12.087. Epub 2009 Dec 23.

PMID:
20034471
17.

Differential coupling of human endothelin type A receptor to G(q/11) and G(12) proteins: the functional significance of receptor expression level in generating multiple receptor signaling.

Horinouchi T, Asano H, Higa T, Nishimoto A, Nishiya T, Muramatsu I, Miwa S.

J Pharmacol Sci. 2009 Dec;111(4):338-51. Epub 2009 Nov 27.

18.

Involvement of cytochrome P450-mediated metabolism in tienilic acid hepatotoxicity in rats.

Nishiya T, Kato M, Suzuki T, Maru C, Kataoka H, Hattori C, Mori K, Jindo T, Tanaka Y, Manabe S.

Toxicol Lett. 2008 Dec 15;183(1-3):81-9. doi: 10.1016/j.toxlet.2008.10.009. Epub 2008 Nov 1.

PMID:
18992796
19.

The crucial protective role of glutathione against tienilic acid hepatotoxicity in rats.

Nishiya T, Mori K, Hattori C, Kai K, Kataoka H, Masubuchi N, Jindo T, Manabe S.

Toxicol Appl Pharmacol. 2008 Oct 15;232(2):280-91. doi: 10.1016/j.taap.2008.06.024. Epub 2008 Jul 22.

PMID:
18708081
20.

Functional role of Na+/H+ exchanger in Ca2+ influx mediated via human endothelin type A receptor stably expressed in Chinese hamster ovary cells.

Horinouchi T, Miyake Y, Nishiya T, Nishimoto A, Morishima S, Muramatsu I, Miwa S.

J Pharmacol Sci. 2008 Aug;107(4):456-9. Epub 2008 Aug 2.

21.

Characterization of noradrenaline-induced increases in intracellular Ca2+ levels in Chinese hamster ovary cells stably expressing human alpha1A-adrenoceptor.

Horinouchi T, Miyake Y, Nishiya T, Nishimoto A, Yorozu S, Jinno A, Kajita E, Miwa S.

J Pharmacol Sci. 2007 Sep;105(1):103-11. Epub 2007 Sep 8.

22.

Ontogenetic changes of ultrasonic vocalizations emitted from infant rats.

Hashimoto H, Moritani N, Katou M, Nishiya T, Kromkhun P, Yokosuka M, Tanaka M, Saito TR.

Exp Anim. 2007 Jul;56(4):315-8.

23.

Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88.

Nishiya T, Kajita E, Horinouchi T, Nishimoto A, Miwa S.

FEBS Lett. 2007 Jul 10;581(17):3223-9. Epub 2007 Jun 15.

24.

OCTN2VT, a splice variant of OCTN2, does not transport carnitine because of the retention in the endoplasmic reticulum caused by insertion of 24 amino acids in the first extracellular loop of OCTN2.

Maekawa S, Mori D, Nishiya T, Takikawa O, Horinouchi T, Nishimoto A, Kajita E, Miwa S.

Biochim Biophys Acta. 2007 Jun;1773(6):1000-6. Epub 2007 Apr 19.

25.

Endothelin-1 decreases [Ca2+]i via Na+/Ca2+ exchanger in CHO cells stably expressing endothelin ETA receptor.

Horinouchi T, Nishimoto A, Nishiya T, Lu L, Kajita E, Miwa S.

Eur J Pharmacol. 2007 Jul 2;566(1-3):28-33. Epub 2007 Mar 24.

PMID:
17445794
26.

Ticlopidine-induced hepatotoxicity is associated with specific human leukocyte antigen genomic subtypes in Japanese patients: a preliminary case-control study.

Hirata K, Takagi H, Yamamoto M, Matsumoto T, Nishiya T, Mori K, Shimizu S, Masumoto H, Okutani Y.

Pharmacogenomics J. 2008 Feb;8(1):29-33. Epub 2007 Mar 6.

PMID:
17339877
27.
28.

Biosensing using lipid bilayers suspended on porous silicon.

Worsfold O, Voelcker NH, Nishiya T.

Langmuir. 2006 Aug 1;22(16):7078-83.

PMID:
16863263
29.

Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2.

Nagai K, Takikawa O, Kawakami N, Fukao M, Soma T, Oda A, Nishiya T, Hayashi M, Lu L, Nakano M, Kajita E, Fujita H, Miwa S.

Arch Biochem Biophys. 2006 Aug 1;452(1):29-37. Epub 2006 Jun 21.

PMID:
16839516
30.

The transmembrane domain directs TLR9 to intracellular compartments that contain TLR3.

Kajita E, Nishiya T, Miwa S.

Biochem Biophys Res Commun. 2006 May 5;343(2):578-84. Epub 2006 Mar 13.

PMID:
16554027
31.

Tienilic acid enhances hyperbilirubinemia in Eisai hyperbilirubinuria rats through hepatic multidrug resistance-associated protein 3 and heme oxygenase-1 induction.

Nishiya T, Kataoka H, Mori K, Goto M, Sugawara T, Furuhama K.

Toxicol Sci. 2006 Jun;91(2):651-9. Epub 2006 Mar 16.

PMID:
16543292
32.

Ligand-independent oligomerization of TLR4 regulated by a short hydrophobic region adjacent to the transmembrane domain.

Nishiya T, Kajita E, Miwa S.

Biochem Biophys Res Commun. 2006 Mar 24;341(4):1128-34. Epub 2006 Jan 26.

PMID:
16460678
33.

Involvement of polyubiquitin chains via specific chain linkages in stress response in mammalian cells.

Fujimuro M, Nishiya T, Nomura Y, Yokosawa H.

Biol Pharm Bull. 2005 Dec;28(12):2315-8.

34.

TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements.

Nishiya T, Kajita E, Miwa S, Defranco AL.

J Biol Chem. 2005 Nov 4;280(44):37107-17. Epub 2005 Aug 16.

35.

Effect of dentures wearing on motor reaction time and balance function in elderly people.

Morozumi K, Yamamoto I, Fujiwara T, Nishiya T, Takeuchi Y, Umeki C, Ichikawa T, Karasuno H.

J Physiol Anthropol Appl Human Sci. 2004 Jul;23(4):129-37.

36.

Interaction of platelets with liposomes containing dodecapeptide sequence from fibrinogen.

Nishiya T, Toma C.

Thromb Haemost. 2004 Jun;91(6):1158-67.

PMID:
15175803
37.

Development of a novel optical bionanosensor.

Worsfold O, Toma C, Nishiya T.

Biosens Bioelectron. 2004 Jun 15;19(11):1505-11.

PMID:
15093223
38.
40.

Platelet interactions with liposomes carrying recombinant platelet membrane glycoproteins or fibrinogen: approach to platelet substitutes.

Nishiya T, Kainoh M, Murata M, Handa M, Ikeda Y.

Artif Cells Blood Substit Immobil Biotechnol. 2001 Nov;29(6):453-64.

PMID:
11795631
41.

Involvement of nuclear factor-kappaB (NF-kappaB) signaling in the expression of inducible nitric oxide synthase (iNOS) gene in rat C6 glioma cells.

Nishiya T, Uehara T, Kaneko M, Nomura Y.

Biochem Biophys Res Commun. 2000 Aug 28;275(2):268-73.

PMID:
10964656
42.
43.

[The intracellular mechanism of NF-kappa B activation involved in iNOS and chemokine induction in C6 glioma cells].

Nomura Y, Uehara T, Nishiya T.

Nihon Yakurigaku Zasshi. 1999 Oct;114 Suppl 1:92P-95P. Japanese.

PMID:
10629862
45.

Effects of kyotorphin (L-tyrosyl-L-arginine) ON[3H]NG-nitro-L-arginine binding to neuronal nitric oxide synthase in rat brain.

Arima T, Kitamura Y, Nishiya T, Taniguchi T, Takagi H, Nomura Y.

Neurochem Int. 1997 Jun;30(6):605-11.

PMID:
9153002
47.

NG-nitro-L-[3H]arginine binding properties of neuronal nitric oxide synthase in rat brain.

Arima T, Kitamura Y, Nishiya T, Kiriyama Y, Taniguchi T, Nomura Y.

Neurochem Int. 1997 Mar;30(3):239-45.

PMID:
9041554
48.

Kyotorphin (L-tyrosyl-L-arginine) as a possible substrate for inducible nitric oxide synthase in rat glial cells.

Arima T, Kitamura Y, Nishiya T, Takagi H, Nomura Y.

Neurosci Lett. 1996 Jul 5;212(1):1-4.

PMID:
8823748
49.

Interaction of RGD liposomes with platelets.

Nishiya T, Sloan S.

Biochem Biophys Res Commun. 1996 Jul 5;224(1):242-5.

PMID:
8694820
50.

Study on in vitro stability of polymerized liposomes.

Nishiya T, Jain B.

Artif Cells Blood Substit Immobil Biotechnol. 1996 Jan;24(1):43-50.

PMID:
8714718

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