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Items: 1 to 50 of 134

1.

β-hydroxybutyrate protects hepatocytes against endoplasmic reticulum stress in a sirtuin 1-independent manner.

Tagawa R, Kawano Y, Minami A, Nishiumi S, Yano Y, Yoshida M, Kodama Y.

Arch Biochem Biophys. 2019 Mar 15;663:220-227. doi: 10.1016/j.abb.2019.01.020. Epub 2019 Jan 18.

PMID:
30664838
2.

Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer.

Iemoto T, Nishiumi S, Kobayashi T, Fujigaki S, Hamaguchi T, Kato K, Shoji H, Matsumura Y, Honda K, Yoshida M.

Oncol Lett. 2019 Jan;17(1):831-842. doi: 10.3892/ol.2018.9731. Epub 2018 Nov 19.

3.

Metabolomics-based Discovery of Serum Biomarkers to Predict the Side-effects of Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma.

Nishiumi S, Fujigaki S, Kobayashi T, Kojima T, Ito Y, Daiko H, Kato K, Shoji H, Kodama Y, Honda K, Yoshida M.

Anticancer Res. 2019 Jan;39(1):519-526. doi: 10.21873/anticanres.13143.

PMID:
30591504
4.

Comparative proteomics of Helicobacter pylori strains reveals geographical features rather than genomic variations.

Sugiyama N, Miyake S, Lin MH, Wakabayashi M, Marusawa H, Nishiumi S, Yoshida M, Ishihama Y.

Genes Cells. 2019 Feb;24(2):139-150. doi: 10.1111/gtc.12662. Epub 2019 Jan 20.

PMID:
30548729
5.

Comparison of venous and fingertip plasma using non-targeted proteomics and metabolomics.

Nishiumi S, Kohata T, Kobayashi T, Kodama Y, Ohtsuki S, Yoshida M.

Talanta. 2019 Jan 15;192:182-188. doi: 10.1016/j.talanta.2018.09.047. Epub 2018 Sep 15.

PMID:
30348376
6.

Exploring a Novel Screening Method for Patients with Oral Squamous Cell Carcinoma: A plasma Metabolomics Analysis.

Enomoto Y, Kimoto A, Suzuki H, Nishiumi S, Yoshida M, Komori T.

Kobe J Med Sci. 2018 Sep 11;64(1):E26-E35.

7.

Alterations in metabolic pathways in gastric epithelial cells infected with Helicobacter pylori.

Matsunaga S, Nishiumi S, Tagawa R, Yoshida M.

Microb Pathog. 2018 Nov;124:122-129. doi: 10.1016/j.micpath.2018.08.033. Epub 2018 Aug 20.

PMID:
30138760
8.

Metabolomics for the early detection of cisplatin-induced nephrotoxicity.

Ezaki T, Nishiumi S, Azuma T, Yoshida M.

Toxicol Res (Camb). 2017 Aug 29;6(6):843-853. doi: 10.1039/c7tx00171a. eCollection 2017 Nov 1.

9.

Increased Levels of Branched-Chain Amino Acid Associated With Increased Risk of Pancreatic Cancer in a Prospective Case-Control Study of a Large Cohort.

Katagiri R, Goto A, Nakagawa T, Nishiumi S, Kobayashi T, Hidaka A, Budhathoki S, Yamaji T, Sawada N, Shimazu T, Inoue M, Iwasaki M, Yoshida M, Tsugane S.

Gastroenterology. 2018 Nov;155(5):1474-1482.e1. doi: 10.1053/j.gastro.2018.07.033. Epub 2018 Aug 1.

PMID:
30076838
10.

Identification of serum biomarkers of chemoradiosensitivity in esophageal cancer via the targeted metabolomics approach.

Fujigaki S, Nishiumi S, Kobayashi T, Suzuki M, Iemoto T, Kojima T, Ito Y, Daiko H, Kato K, Shouji H, Honda K, Azuma T, Yoshida M.

Biomark Med. 2018 Aug;12(8):827-840. doi: 10.2217/bmm-2017-0449. Epub 2018 Jul 25.

PMID:
30043633
11.

[Possibility of Metabolite Biomarkers for Early Detection of Cancer].

Nishiumi S, Yoshida M.

Gan To Kagaku Ryoho. 2018 Jun;45(6):894-898. Japanese.

PMID:
30026409
12.

Metabolome analysis for pancreatic cancer risk in nested case-control study: Japan Public Health Center-based prospective Study.

Nakagawa T, Kobayashi T, Nishiumi S, Hidaka A, Yamaji T, Sawada N, Hirata Y, Yamanaka K, Azuma T, Goto A, Shimazu T, Inoue M, Iwasaki M, Yoshida M, Tsugane S.

Cancer Sci. 2018 May;109(5):1672-1681. doi: 10.1111/cas.13573. Epub 2018 Apr 16.

13.

Alterations in Docosahexaenoic Acid-Related Lipid Cascades in Inflammatory Bowel Disease Model Mice.

Nishiumi S, Izumi Y, Yoshida M.

Dig Dis Sci. 2018 Jun;63(6):1485-1496. doi: 10.1007/s10620-018-5025-4. Epub 2018 Mar 21.

PMID:
29564669
14.

Serum apolipoprotein A2 isoforms in autoimmune pancreatitis.

Kobayashi T, Sato Y, Nishiumi S, Yagi Y, Sakai A, Shiomi H, Masuda A, Okaya S, Kutsumi H, Yoshida M, Honda K.

Biochem Biophys Res Commun. 2018 Mar 11;497(3):903-907. doi: 10.1016/j.bbrc.2018.02.170. Epub 2018 Feb 23.

PMID:
29481802
15.

Associations Between CagA, VacA, and the Clinical Outcomes of Helicobacter Pylori Infections in Okinawa, Japan.

Inagaki T, Nishiumi S, Ito Y, Yamakawa A, Yamazaki Y, Yoshida M, Azuma T.

Kobe J Med Sci. 2017 Nov 22;63(2):E58-E67.

16.

Differences in metabolite profiles caused by pre-analytical blood processing procedures.

Nishiumi S, Suzuki M, Kobayashi T, Yoshida M.

J Biosci Bioeng. 2018 May;125(5):613-618. doi: 10.1016/j.jbiosc.2017.11.011. Epub 2017 Dec 16.

PMID:
29258730
17.

Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer.

Yamashita Y, Nishiumi S, Kono S, Takao S, Azuma T, Yoshida M.

BMC Cancer. 2017 Aug 29;17(1):589. doi: 10.1186/s12885-017-3554-4.

18.

Novel serum metabolomics-based approach by gas chromatography/triple quadrupole mass spectrometry for detection of human skin cancers: Candidate biomarkers.

Fukumoto T, Nishiumi S, Fujiwara S, Yoshida M, Nishigori C.

J Dermatol. 2017 Nov;44(11):1268-1275. doi: 10.1111/1346-8138.13921. Epub 2017 Jun 8.

PMID:
28593747
19.

Alterations in metabolic pathways in stomach of mice infected with Helicobacter pylori.

Nishiumi S, Yoshida M, Azuma T.

Microb Pathog. 2017 Aug;109:78-85. doi: 10.1016/j.micpath.2017.05.027. Epub 2017 May 22.

PMID:
28546118
20.

Indigo Naturalis Ameliorates Oxazolone-Induced Dermatitis but Aggravates Colitis by Changing the Composition of Gut Microflora.

Adachi S, Hoshi N, Inoue J, Yasutomi E, Otsuka T, Dhakhwa R, Wang Z, Koo Y, Takamatsu T, Matsumura Y, Yamairi H, Watanabe D, Ooi M, Tanahashi T, Nishiumi S, Yoshida M, Azuma T.

Int Arch Allergy Immunol. 2017;173(1):23-33. doi: 10.1159/000471923. Epub 2017 May 9.

PMID:
28482341
21.

Adrenic acid as an inflammation enhancer in non-alcoholic fatty liver disease.

Horas H Nababan S, Nishiumi S, Kawano Y, Kobayashi T, Yoshida M, Azuma T.

Arch Biochem Biophys. 2017 Jun 1;623-624:64-75. doi: 10.1016/j.abb.2017.04.009. Epub 2017 Apr 26.

PMID:
28456640
22.

Genetic variants of Helicobacter pylori type IV secretion system components CagL and CagI and their association with clinical outcomes.

Ogawa H, Iwamoto A, Tanahashi T, Okada R, Yamamoto K, Nishiumi S, Yoshida M, Azuma T.

Gut Pathog. 2017 Apr 21;9:21. doi: 10.1186/s13099-017-0165-1. eCollection 2017.

23.

Use of on-line supercritical fluid extraction-supercritical fluid chromatography/tandem mass spectrometry to analyze disease biomarkers in dried serum spots compared with serum analysis using liquid chromatography/tandem mass spectrometry.

Suzuki M, Nishiumi S, Kobayashi T, Sakai A, Iwata Y, Uchikata T, Izumi Y, Azuma T, Bamba T, Yoshida M.

Rapid Commun Mass Spectrom. 2017 May 30;31(10):886-894. doi: 10.1002/rcm.7857.

PMID:
28332299
24.

Astilbin from Engelhardtia chrysolepis enhances intestinal barrier functions in Caco-2 cell monolayers.

Nakahara T, Nishitani Y, Nishiumi S, Yoshida M, Azuma T.

Eur J Pharmacol. 2017 Jun 5;804:46-51. doi: 10.1016/j.ejphar.2017.03.041. Epub 2017 Mar 19.

PMID:
28327343
25.

Evaluation of a novel system for analyzing hydrophilic blood metabolites.

Nishiumi S, Shima K, Azuma T, Yoshida M.

J Biosci Bioeng. 2017 Jun;123(6):754-759. doi: 10.1016/j.jbiosc.2017.01.015. Epub 2017 Mar 11.

PMID:
28291661
26.

Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics.

Hirata Y, Kobayashi T, Nishiumi S, Yamanaka K, Nakagawa T, Fujigaki S, Iemoto T, Kobayashi M, Okusaka T, Nakamori S, Shimahara M, Ueno T, Tsuchida A, Sata N, Ioka T, Yasunami Y, Kosuge T, Kaneda T, Kato T, Yagihara K, Fujita S, Yamada T, Honda K, Azuma T, Yoshida M.

Clin Chim Acta. 2017 May;468:98-104. doi: 10.1016/j.cca.2017.02.011. Epub 2017 Feb 16.

PMID:
28215548
27.

Investigations in the possibility of early detection of colorectal cancer by gas chromatography/triple-quadrupole mass spectrometry.

Nishiumi S, Kobayashi T, Kawana S, Unno Y, Sakai T, Okamoto K, Yamada Y, Sudo K, Yamaji T, Saito Y, Kanemitsu Y, Okita NT, Saito H, Tsugane S, Azuma T, Ojima N, Yoshida M.

Oncotarget. 2017 Mar 7;8(10):17115-17126. doi: 10.18632/oncotarget.15081.

28.

Population Evolution of Helicobacter pylori through Diversification in DNA Methylation and Interstrain Sequence Homogenization.

Kojima KK, Furuta Y, Yahara K, Fukuyo M, Shiwa Y, Nishiumi S, Yoshida M, Azuma T, Yoshikawa H, Kobayashi I.

Mol Biol Evol. 2016 Nov;33(11):2848-2859. Epub 2016 Sep 7.

PMID:
27604221
29.

Rapid Preparation of a Plasma Membrane Fraction: Western Blot Detection of Translocated Glucose Transporter 4 from Plasma Membrane of Muscle and Adipose Cells and Tissues.

Yamamoto N, Yamashita Y, Yoshioka Y, Nishiumi S, Ashida H.

Curr Protoc Protein Sci. 2016 Aug 1;85:29.18.1-29.18.12. doi: 10.1002/cpps.13.

PMID:
27479506
30.

Pancreatic cancer screening using a multiplatform human serum metabolomics system.

Sakai A, Suzuki M, Kobayashi T, Nishiumi S, Yamanaka K, Hirata Y, Nakagawa T, Azuma T, Yoshida M.

Biomark Med. 2016 Jun;10(6):577-86. doi: 10.2217/bmm-2016-0020. Epub 2016 May 12.

PMID:
27171159
31.

Postmortem interval estimation: a novel approach utilizing gas chromatography/mass spectrometry-based biochemical profiling.

Kaszynski RH, Nishiumi S, Azuma T, Yoshida M, Kondo T, Takahashi M, Asano M, Ueno Y.

Anal Bioanal Chem. 2016 May;408(12):3103-12. doi: 10.1007/s00216-016-9355-9. Epub 2016 Mar 1.

PMID:
26931122
32.

Multi-Component Profiling of Trace Volatiles in Blood by Gas Chromatography/Mass Spectrometry with Dynamic Headspace Extraction.

Kakuta S, Yamashita T, Nishiumi S, Yoshida M, Fukusaki E, Bamba T.

Mass Spectrom (Tokyo). 2015;4(1):A0034. doi: 10.5702/massspectrometry.A0034. Epub 2015 Jan 15.

33.

Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.

Shimoda A, Ueda K, Nishiumi S, Murata-Kamiya N, Mukai SA, Sawada S, Azuma T, Hatakeyama M, Akiyoshi K.

Sci Rep. 2016 Jan 7;6:18346. doi: 10.1038/srep18346.

34.

[Gastroenterological Cancer Diagnosis by Metabolomics-Discovery of Pancreatic Cancer Biomarker].

Yoshida M, Nishiumi S, Azuma T.

Rinsho Byori. 2015 Apr;63(4):450-6. Review. Japanese.

PMID:
26536778
35.

Rikkunshito Ameliorates Cancer Cachexia Partly through Elevation of Glucarate in Plasma.

Ohbuchi K, Nishiumi S, Fujitsuka N, Hattori T, Yamamoto M, Inui A, Azuma T, Yoshida M.

Evid Based Complement Alternat Med. 2015;2015:871832. doi: 10.1155/2015/871832. Epub 2015 Sep 15.

36.

Profiling of volatile compounds in APC(Min/+) mice blood by dynamic headspace extraction and gas chromatography/mass spectrometry.

Kakuta S, Nishiumi S, Yoshida M, Fukusaki E, Bamba T.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:35-40. doi: 10.1016/j.jchromb.2015.09.002. Epub 2015 Sep 11.

PMID:
26406113
37.

Identification of Lipid Species Linked to the Progression of Non-Alcoholic Fatty Liver Disease.

Kawano Y, Nishiumi S, Saito M, Yano Y, Azuma T, Yoshida M.

Curr Drug Targets. 2015;16(12):1293-300. Review.

PMID:
25850622
38.

Catechins in tea suppress the activity of cytochrome P450 1A1 through the aryl hydrocarbon receptor activation pathway in rat livers.

Fukuda I, Nishiumi S, Mukai R, Yoshida K, Ashida H.

Int J Food Sci Nutr. 2015 May;66(3):300-7. doi: 10.3109/09637486.2014.992007. Epub 2015 Jan 13.

PMID:
25582180
39.

Metabolomics evaluation of serum markers for cachexia and their intra-day variation in patients with advanced pancreatic cancer.

Fujiwara Y, Kobayashi T, Chayahara N, Imamura Y, Toyoda M, Kiyota N, Mukohara T, Nishiumi S, Azuma T, Yoshida M, Minami H.

PLoS One. 2014 Nov 20;9(11):e113259. doi: 10.1371/journal.pone.0113259. eCollection 2014.

40.

Protective effects of oral administration of yeast thioredoxin against gastric mucosal injury.

Taketani Y, Kinugasa K, Kitajima R, Nishiumi S, Ashida H, Nakamura H, Fujita T, Kanzaki K, Masutani H, Yodoi J.

Biosci Biotechnol Biochem. 2014;78(7):1221-30. doi: 10.1080/09168451.2014.915733. Epub 2014 Jun 18.

PMID:
25229862
41.

Supercritical fluid extraction as a preparation method for mass spectrometry of dried blood spots.

Matsubara A, Izumi Y, Nishiumi S, Suzuki M, Azuma T, Fukusaki E, Bamba T, Yoshida M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 15;969:199-204. doi: 10.1016/j.jchromb.2014.08.013. Epub 2014 Aug 17.

PMID:
25178194
42.

The influences of pepsin concentrations and pH levels on the disinfective activity of ozone nanobubble water against helicobacter pylori.

Kawara F, Inoue J, Takenaka M, Hoshi N, Masuda A, Nishiumi S, Kutsumi H, Azuma T, Ohdaira T.

Digestion. 2014;90(1):10-7. doi: 10.1159/000358286. Epub 2014 Jul 30.

PMID:
25096714
43.

Interferon-γ-producing B cells induce the formation of gastric lymphoid follicles after Helicobacter suis infection.

Yang L, Yamamoto K, Nishiumi S, Nakamura M, Matsui H, Takahashi S, Dohi T, Okada T, Kakimoto K, Hoshi N, Yoshida M, Azuma T.

Mucosal Immunol. 2015 Mar;8(2):279-95. doi: 10.1038/mi.2014.66. Epub 2014 Jul 30.

PMID:
25073677
44.

Metabolomics for biomarker discovery in gastroenterological cancer.

Nishiumi S, Suzuki M, Kobayashi T, Matsubara A, Azuma T, Yoshida M.

Metabolites. 2014 Jul 7;4(3):547-71. doi: 10.3390/metabo4030547.

45.

Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes.

Iwamoto A, Tanahashi T, Okada R, Yoshida Y, Kikuchi K, Keida Y, Murakami Y, Yang L, Yamamoto K, Nishiumi S, Yoshida M, Azuma T.

Gut Pathog. 2014 Jun 26;6:27. doi: 10.1186/1757-4749-6-27. eCollection 2014.

46.

Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis.

Terashima Y, Nishiumi S, Minami A, Kawano Y, Hoshi N, Azuma T, Yoshida M.

Arch Biochem Biophys. 2014 Aug;555-556:55-65. doi: 10.1016/j.abb.2014.05.013. Epub 2014 May 22.

PMID:
24857839
47.

Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization.

Kawano Y, Ersoy BA, Li Y, Nishiumi S, Yoshida M, Cohen DE.

Mol Cell Biol. 2014 Jul;34(13):2396-408. doi: 10.1128/MCB.01601-13. Epub 2014 Apr 14.

48.

Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection.

Yamamoto K, Nishiumi S, Yang L, Klimatcheva E, Pandina T, Takahashi S, Matsui H, Nakamura M, Zauderer M, Yoshida M, Azuma T.

Mucosal Immunol. 2014 Sep;7(5):1244-54. doi: 10.1038/mi.2014.14. Epub 2014 Mar 19.

PMID:
24646940
49.

Metabolome analysis for discovering biomarkers of gastroenterological cancer.

Suzuki M, Nishiumi S, Matsubara A, Azuma T, Yoshida M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:59-69. doi: 10.1016/j.jchromb.2014.02.042. Epub 2014 Mar 1. Review.

PMID:
24636738
50.

A novel gas chromatography mass spectrometry-based serum diagnostic and assessment approach to ulcerative colitis.

Kohashi M, Nishiumi S, Ooi M, Yoshie T, Matsubara A, Suzuki M, Hoshi N, Kamikozuru K, Yokoyama Y, Fukunaga K, Nakamura S, Azuma T, Yoshida M.

J Crohns Colitis. 2014 Sep;8(9):1010-21. doi: 10.1016/j.crohns.2014.01.024. Epub 2014 Feb 26.

PMID:
24582087

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