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Items: 1 to 50 of 58

1.

Repurposing Potential of Riluzole as an ITAF Inhibitor in mTOR Therapy Resistant Glioblastoma.

Benavides-Serrato A, Saunders JT, Holmes B, Nishimura RN, Lichtenstein A, Gera J.

Int J Mol Sci. 2020 Jan 5;21(1). pii: E344. doi: 10.3390/ijms21010344.

2.

The protein arginine methyltransferase PRMT5 confers therapeutic resistance to mTOR inhibition in glioblastoma.

Holmes B, Benavides-Serrato A, Saunders JT, Landon KA, Schreck AJ, Nishimura RN, Gera J.

J Neurooncol. 2019 Oct;145(1):11-22. doi: 10.1007/s11060-019-03274-0. Epub 2019 Aug 31.

PMID:
31473880
3.

Development of an acute, short-term exposure model for phosgene.

Hobson ST, Casillas RP, Richieri RA, Nishimura RN, Weisbart RH, Tuttle R, Reynolds GT, Parseghian MH.

Toxicol Mech Methods. 2019 Oct;29(8):604-615. doi: 10.1080/15376516.2019.1636170. Epub 2019 Jul 16.

PMID:
31237465
4.

mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.

Holmes B, Benavides-Serrato A, Freeman RS, Landon KA, Bashir T, Nishimura RN, Gera J.

Oncogene. 2018 Feb 8;37(6):732-743. doi: 10.1038/onc.2017.360. Epub 2017 Oct 23.

5.

Combining intracellular antibodies to restore function of mutated p53 in cancer.

Chan G, Jordaan G, Nishimura RN, Weisbart RH.

Int J Cancer. 2016 Jan 1;138(1):182-6. doi: 10.1002/ijc.29685. Epub 2015 Sep 3.

6.

DNA-dependent targeting of cell nuclei by a lupus autoantibody.

Weisbart RH, Chan G, Jordaan G, Noble PW, Liu Y, Glazer PM, Nishimura RN, Hansen JE.

Sci Rep. 2015 Jul 9;5:12022. doi: 10.1038/srep12022.

7.

BRAF splice variants in rheumatoid arthritis synovial fibroblasts activate MAPK through CRAF.

Weisbart RH, Chan G, Li E, Farmani N, Heinze E, Rubell A, Nishimura RN, Colburn K.

Mol Immunol. 2013 Oct;55(3-4):247-52. doi: 10.1016/j.molimm.2013.02.001. Epub 2013 Mar 19.

PMID:
23517740
8.

Targeting cancer with a lupus autoantibody.

Hansen JE, Chan G, Liu Y, Hegan DC, Dalal S, Dray E, Kwon Y, Xu Y, Xu X, Peterson-Roth E, Geiger E, Liu Y, Gera J, Sweasy JB, Sung P, Rockwell S, Nishimura RN, Weisbart RH, Glazer PM.

Sci Transl Med. 2012 Oct 24;4(157):157ra142. doi: 10.1126/scitranslmed.3004385.

9.

Conditional astroglial Rictor overexpression induces malignant glioma in mice.

Bashir T, Cloninger C, Artinian N, Anderson L, Bernath A, Holmes B, Benavides-Serrato A, Sabha N, Nishimura RN, Guha A, Gera J.

PLoS One. 2012;7(10):e47741. doi: 10.1371/journal.pone.0047741. Epub 2012 Oct 15.

10.

A cell-penetrating bispecific antibody for therapeutic regulation of intracellular targets.

Weisbart RH, Gera JF, Chan G, Hansen JE, Li E, Cloninger C, Levine AJ, Nishimura RN.

Mol Cancer Ther. 2012 Oct;11(10):2169-73. doi: 10.1158/1535-7163.MCT-12-0476-T. Epub 2012 Aug 3.

11.

Tumor suppressor and T-regulatory functions of Foxp3 are mediated through separate signaling pathways.

Heinze E, Chan G, Mory R, Khavari R, Alavi A, Chung SY, Nishimura RN, Weisbart RH.

Oncol Lett. 2011 Jul;2(4):665-668. Epub 2011 May 13.

12.

BRAF drives synovial fibroblast transformation in rheumatoid arthritis.

Weisbart RH, Chan G, Heinze E, Mory R, Nishimura RN, Colburn K.

J Biol Chem. 2010 Nov 5;285(45):34299-303. doi: 10.1074/jbc.C110.168195. Epub 2010 Sep 14.

13.

Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats.

Zhan X, Ander BP, Liao IH, Hansen JE, Kim C, Clements D, Weisbart RH, Nishimura RN, Sharp FR.

Stroke. 2010 Mar;41(3):538-43. doi: 10.1161/STROKEAHA.109.572537. Epub 2010 Jan 14.

14.

Hsp70 associates with Rictor and is required for mTORC2 formation and activity.

Martin J, Masri J, Bernath A, Nishimura RN, Gera J.

Biochem Biophys Res Commun. 2008 Aug 8;372(4):578-83. doi: 10.1016/j.bbrc.2008.05.086. Epub 2008 May 27.

15.

Intranuclear protein transduction through a nucleoside salvage pathway.

Hansen JE, Tse CM, Chan G, Heinze ER, Nishimura RN, Weisbart RH.

J Biol Chem. 2007 Jul 20;282(29):20790-3. Epub 2007 May 24.

16.

Antibody-mediated p53 protein therapy prevents liver metastasis in vivo.

Hansen JE, Fischer LK, Chan G, Chang SS, Baldwin SW, Aragon RJ, Carter JJ, Lilly M, Nishimura RN, Weisbart RH, Reeves ME.

Cancer Res. 2007 Feb 15;67(4):1769-74.

17.

Antibody-mediated Hsp70 protein therapy.

Hansen JE, Sohn W, Kim C, Chang SS, Huang NC, Santos DG, Chan G, Weisbart RH, Nishimura RN.

Brain Res. 2006 May 9;1088(1):187-96. Epub 2006 Apr 21.

PMID:
16630585
18.

Antibody mediated transduction of therapeutic proteins into living cells.

Hansen JE, Weisbart RH, Nishimura RN.

ScientificWorldJournal. 2005 Sep 16;5:782-8. Review.

19.

Selective IgA immune unresponsiveness to Proteus mirabilis fumarate reductase A-chain in rheumatoid arthritis.

Weisbart RH, Min Y, Wong AL, Kang J, Kwunyeun S, Lin A, Kim J, Chan G, Wakelin R, Sohn W, Chang SS, Nishimura RN.

J Rheumatol. 2005 Jul;32(7):1208-12.

PMID:
15996053
20.

Heat shock proteins and neuromuscular disease.

Nishimura RN, Sharp FR.

Muscle Nerve. 2005 Dec;32(6):693-709. Review.

PMID:
15962334
21.

An intracellular delivery vehicle for protein transduction of micro-dystrophin.

Weisbart RH, Hansen JE, Nishimura RN, Chan G, Wakelin R, Chang SS, Baresi L, Chamberlain JS.

J Drug Target. 2005 Feb;13(2):81-7.

PMID:
15823959
22.

Antibody-mediated transduction of p53 selectively kills cancer cells.

Weisbart RH, Hansen JE, Chan G, Wakelin R, Chang SS, Heinze E, Miller CW, Koeffler PH, Yang F, Cole GM, Min YS, Nishimura RN.

Int J Oncol. 2004 Dec;25(6):1867-73.

PMID:
15547728
23.

Expression of antisense hsp70 is a major determining factor in heat-induced cell death of P-19 carcinoma cells.

Nishimura RN, Santos D, Esmaili L, Fu ST, Dwyer BE.

Cell Stress Chaperones. 2000 Jul;5(3):173-80.

24.

Induction of cell death by L-alpha-aminoadipic acid exposure in cultured rat astrocytes: relationship to protein synthesis.

Nishimura RN, Santos D, Fu ST, Dwyer BE.

Neurotoxicology. 2000 Jun;21(3):313-20.

PMID:
10894121
25.

Tin-mesoporphyrin, a potent heme oxygenase inhibitor, for treatment of intracerebral hemorrhage: in vivo and in vitro studies.

Wagner KR, Hua Y, de Courten-Myers GM, Broderick JP, Nishimura RN, Lu SY, Dwyer BE.

Cell Mol Biol (Noisy-le-grand). 2000 May;46(3):597-608.

PMID:
10872746
26.

The extracellular calcium-sensing receptor is expressed in rat microglia and modulates an outward K+ channel.

Chattopadhyay N, Ye C, Yamaguchi T, Nakai M, Kifor O, Vassilev PM, Nishimura RN, Brown EM.

J Neurochem. 1999 May;72(5):1915-22.

27.

Apoptosis in a neonatal rat model of cerebral hypoxia-ischemia.

Pulera MR, Adams LM, Liu H, Santos DG, Nishimura RN, Yang F, Cole GM, Wasterlain CG.

Stroke. 1998 Dec;29(12):2622-30.

PMID:
9836776
28.
29.

Heme oxygenase in the experimental ALS mouse.

Dwyer BE, Lu SY, Nishimura RN.

Exp Neurol. 1998 Apr;150(2):206-12.

PMID:
9527889
30.

Transient induction of heme oxygenase after cortical stab wound injury.

Dwyer BE, Nishimura RN, Lu SY, Alcaraz A.

Brain Res Mol Brain Res. 1996 Jun;38(2):251-9.

PMID:
8793113
31.
32.

Localization of heme oxygenase in rat retina: effect of light adaptation.

Nishimura RN, Dwyer BE, Lu SY.

Neurosci Lett. 1996 Feb 16;205(1):13-6.

PMID:
8867009
33.

Neuroprotection against CA1 injury with metalloporphyrins.

Panizzon KL, Dwyer BE, Nishimura RN, Wallis RA.

Neuroreport. 1996 Jan 31;7(2):662-6.

PMID:
8730852
34.

Pharmacological induction of heat shock protein 68 synthesis in cultured rat astrocytes.

Nishimura RN, Dwyer BE.

J Biol Chem. 1995 Dec 15;270(50):29967-70.

35.

Differential localization of heme oxygenase and NADPH-diaphorase in spinal cord neurons.

Dwyer BE, Nishimura RN, Lu SY.

Neuroreport. 1995 May 9;6(7):973-6.

PMID:
7632902
37.

Heat shock proteins in hypoxic-ischemic brain injury: a perspective.

Dwyer BE, Nishimura RN.

Brain Pathol. 1992 Jul;2(3):245-51. Review.

PMID:
1343840
38.

Heme oxygenase is a heat shock protein and PEST protein in rat astroglial cells.

Dwyer BE, Nishimura RN, De Vellis J, Yoshida T.

Glia. 1992;5(4):300-5.

PMID:
1375192
39.

Characterization of the major 68 kDa heat shock protein in a rat transformed astroglial cell line.

Nishimura RN, Dwyer BE, de Vellis J, Clegg KB.

Brain Res Mol Brain Res. 1992 Jan;12(1-3):203-8.

PMID:
1312202
40.

Heat shock in cultured neurons and astrocytes: correlation of ultrastructure and heat shock protein synthesis.

Nishimura RN, Dwyer BE, Vinters HV, De Vellis J, Cole R.

Neuropathol Appl Neurobiol. 1991 Apr;17(2):139-47.

PMID:
1857489
41.

Regulation of heat shock protein synthesis in rat astrocytes.

Dwyer BE, Nishimura RN, de Vellis J, Clegg KB.

J Neurosci Res. 1991 Mar;28(3):352-8.

PMID:
1856882
42.

Comparison of the heat shock response in cultured cortical neurons and astrocytes.

Nishimura RN, Dwyer BE, Clegg K, Cole R, de Vellis J.

Brain Res Mol Brain Res. 1991 Jan;9(1-2):39-45.

PMID:
1850077
43.

Synthesis of the major inducible heat shock protein in rat hippocampus after neonatal hypoxia-ischemia.

Dwyer BE, Nishimura RN, Brown IR.

Exp Neurol. 1989 Apr;104(1):28-31.

PMID:
2924867
44.

Induction of the major inducible 68-kDa heat-shock protein after rapid changes of extracellular pH in cultured rat astrocytes.

Nishimura RN, Dwyer BE, Cole R, de Vellis J, Picard K.

Exp Cell Res. 1989 Jan;180(1):276-80.

PMID:
2909393
45.

The induction of the major heat-stress protein in purified rat glial cells.

Nishimura RN, Dwyer BE, Welch W, Cole R, de Vellis J, Liotta K.

J Neurosci Res. 1988 May;20(1):12-8.

PMID:
3418750
46.

Cerebral hypoxia-ischemia in immature rats: methodological considerations.

Dwyer BE, Nishimura RN, Fujikawa DG.

Exp Neurol. 1988 Mar;99(3):772-7.

PMID:
3342854
47.

Focal protein synthesis inhibition in a model of neonatal hypoxic-ischemic brain injury.

Dwyer BE, Nishimura RN, Powell CL, Mailheau SL.

Exp Neurol. 1987 Feb;95(2):277-89.

PMID:
3803515
48.

L-fucose labeling of brain tumors in rats.

Harsh GR, Nishimura RN, Dwyer BE, Levin VA.

Exp Neurol. 1986 Oct;94(1):21-8.

PMID:
3758281
49.

Quantitation of myelination and demyelination by the measurement of myelin basic protein by ELISA.

Nishimura RN, Wang J, Merrill JE, Mickey MR, Myers LW.

J Neurol Sci. 1986 May;73(3):317-24.

PMID:
2425056
50.

Myelination of mouse cerebellar explants by rat cultured oligodendrocytes.

Nishimura RN, Blank NK, Tiekotter KL, Cole R, de Vellis J.

Brain Res. 1985 Jun 24;337(1):159-62.

PMID:
4005604

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