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Items: 1 to 50 of 205

1.

A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.

Sun Q, Lee W, Mohri Y, Takeo M, Lim CH, Xu X, Myung P, Atit RP, Taketo MM, Moubarak RS, Schober M, Osman I, Gay DL, Saur D, Nishimura EK, Ito M.

Nat Commun. 2019 Nov 4;10(1):5023. doi: 10.1038/s41467-019-12733-1.

2.

Correction to: Effects of enzymatically modified isoquercitrin in supplementary protein powder on athlete body composition: a randomized, placebo-controlled, doubleblind trial.

Omi N, Shiba H, Nishimura E, Tsukamoto S, Maruki-Uchida H, Oda M, Morita M.

J Int Soc Sports Nutr. 2019 Oct 21;16(1):45. doi: 10.1186/s12970-019-0315-6.

3.

Effects of enzymatically modified isoquercitrin in supplementary protein powder on athlete body composition: a randomized, placebo-controlled, double-blind trial.

Omi N, Shiba H, Nishimura E, Tsukamoto S, Maruki-Uchida H, Oda M, Morita M.

J Int Soc Sports Nutr. 2019 Sep 10;16(1):39. doi: 10.1186/s12970-019-0303-x. Erratum in: J Int Soc Sports Nutr. 2019 Oct 21;16(1):45.

4.

Growth and antibiotic resistance acquisition of Escherichia coli in a river that receives treated sewage effluent.

Suzuki Y, Hashimoto R, Xie H, Nishimura E, Nishiyama M, Nukazawa K, Ishii S.

Sci Total Environ. 2019 Nov 10;690:696-704. doi: 10.1016/j.scitotenv.2019.07.050. Epub 2019 Jul 4.

PMID:
31301509
5.

Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine.

Hvid H, Kildegaard J, Kristensen K, Porsgaard T, Jørgensen MS, Ballarín-González B, Ahnfelt-Rønne J, Hansen BF, Nishimura E.

J Diabetes Sci Technol. 2019 Jun 12:1932296819855075. doi: 10.1177/1932296819855075. [Epub ahead of print]

PMID:
31189343
6.

Peripherally delivered hepatopreferential insulin analog insulin-406 mimics the hypoglycaemia-sparing effect of portal vein human insulin infusion in dogs.

Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Madsen P, Kjeldsen TB, Hostrup S, Brand CL, Fledelius C, Nishimura E, Cherrington AD.

Diabetes Obes Metab. 2019 Oct;21(10):2294-2304. doi: 10.1111/dom.13808. Epub 2019 Jul 8.

PMID:
31183936
7.

IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenance.

Muraguchi T, Nanba D, Nishimura EK, Tashiro T.

J Dermatol Sci. 2019 May;94(2):298-305. doi: 10.1016/j.jdermsci.2019.05.001. Epub 2019 May 11.

PMID:
31122679
8.

Stem cell competition orchestrates skin homeostasis and ageing.

Liu N, Matsumura H, Kato T, Ichinose S, Takada A, Namiki T, Asakawa K, Morinaga H, Mohri Y, De Arcangelis A, Geroges-Labouesse E, Nanba D, Nishimura EK.

Nature. 2019 Apr;568(7752):344-350. doi: 10.1038/s41586-019-1085-7. Epub 2019 Apr 3.

PMID:
30944469
9.

Prevalence and significance of sleep disordered breathing in adolescent athletes.

Iso Y, Kitai H, Kyuno E, Tsunoda F, Nishinaka N, Funato M, Nishimura E, Akihiro S, Tanuma H, Yonechi T, Geshi E, Sambe T, Suzuki H.

ERJ Open Res. 2019 Mar 11;5(1). pii: 00029-2019. doi: 10.1183/23120541.00029-2019. eCollection 2019 Feb.

10.

Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.

Edgerton DS, Scott M, Farmer B, Williams PE, Madsen P, Kjeldsen T, Brand CL, Fledelius C, Nishimura E, Cherrington AD.

JCI Insight. 2019 Feb 26;5. pii: 126974. doi: 10.1172/jci.insight.126974.

11.

Beclin 1 regulates recycling endosome and is required for skin development in mice.

Noguchi S, Honda S, Saitoh T, Matsumura H, Nishimura E, Akira S, Shimizu S.

Commun Biol. 2019 Jan 25;2:37. doi: 10.1038/s42003-018-0279-0. eCollection 2019.

12.

Novel Strategy for the Systemic Delivery of Furosemide Based on a New Drug Transport Mechanism.

Kimura S, Kiriyama A, Nishimura E, Sakata S, Inoue D, Furubayashi T, Yutani R, Tanaka A, Kusamori K, Katsumi H, Iga K, Yamamoto A, Sakane T.

Biol Pharm Bull. 2018;41(12):1769-1777. doi: 10.1248/bpb.b18-00315.

13.

Inadequate Clinical Indications in Computed Tomography Chest and Abdomen/Pelvis Scans.

Finger A, Harris M, Nishimura E, Yoon HC.

Perm J. 2018;22:18-017. doi: 10.7812/TPP/18-017.

14.

A case of portal vein thrombosis caused by blunt abdominal trauma in a patient with low protein C activity.

Nishimura E, Misawa T, Kitamura H, Fujioka S, Akiba T, Yanaga K.

Clin J Gastroenterol. 2018 Dec;11(6):507-513. doi: 10.1007/s12328-018-0879-8. Epub 2018 Jun 19. Review.

PMID:
29923164
15.

iNOS inhibits hair regeneration in obese diabetic (ob/ob) mice.

Sasaki M, Shinozaki S, Morinaga H, Kaneki M, Nishimura E, Shimokado K.

Biochem Biophys Res Commun. 2018 Jul 2;501(4):893-897. doi: 10.1016/j.bbrc.2018.05.071. Epub 2018 May 18.

16.

A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2.

Wiesenfahrt T, Duanmu J, Snider F, Moerman D, Au V, Li-Leger E, Flibotte S, Parker DM, Marshall CJ, Nishimura EO, Mains PE, McGhee JD.

G3 (Bethesda). 2018 May 4;8(5):1425-1437. doi: 10.1534/g3.118.200079.

17.

Sigmoidocolocystoplasty for neurogenic bladder reviewed after 20 years.

Hayashi Y, Nishimura E, Shimizu S, Miyano G, Okawada M, Nagae I, Lane GJ, Katsumata K, Yamataka A, Tsuchida A.

J Pediatr Surg. 2017 Dec;52(12):2070-2073. doi: 10.1016/j.jpedsurg.2017.08.029. Epub 2017 Sep 2.

PMID:
29223546
18.

Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors.

Jensen SR, Schoof EM, Wheeler SE, Hvid H, Ahnfelt-Rønne J, Hansen BF, Nishimura E, Olsen GS, Kislinger T, Brubaker PL.

Endocrinology. 2017 Aug 1;158(8):2470-2485. doi: 10.1210/en.2017-00194.

PMID:
28591806
19.

Elucidating the Biological Roles of Insulin and Its Receptor in Murine Intestinal Growth and Function.

Jensen SR, Wheeler SE, Hvid H, Ahnfelt-Rønne J, Hansen BF, Nishimura E, Olsen GS, Brubaker PL.

Endocrinology. 2017 Aug 1;158(8):2453-2469. doi: 10.1210/en.2017-00195.

PMID:
28591779
20.

Lipophilic triphenylphosphonium derivatives enhance radiation-induced cell killing via inhibition of mitochondrial energy metabolism in tumor cells.

Yasui H, Yamamoto K, Suzuki M, Sakai Y, Bo T, Nagane M, Nishimura E, Yamamori T, Yamasaki T, Yamada KI, Inanami O.

Cancer Lett. 2017 Apr 1;390:160-167. doi: 10.1016/j.canlet.2017.01.006. Epub 2017 Jan 16.

21.

Pancreatic α-cell hyperplasia and hyperglucagonemia due to a glucagon receptor splice mutation.

Larger E, Wewer Albrechtsen NJ, Hansen LH, Gelling RW, Capeau J, Deacon CF, Madsen OD, Yakushiji F, De Meyts P, Holst JJ, Nishimura E.

Endocrinol Diabetes Metab Case Rep. 2016;2016. pii: 16-0081. Epub 2016 Nov 21.

22.

p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress.

Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.

Cell Stem Cell. 2016 Aug 4;19(2):192-204. doi: 10.1016/j.stem.2016.05.013. Epub 2016 Jun 23.

23.

Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis.

Matsumura H, Mohri Y, Binh NT, Morinaga H, Fukuda M, Ito M, Kurata S, Hoeijmakers J, Nishimura EK.

Science. 2016 Feb 5;351(6273):aad4395. doi: 10.1126/science.aad4395. Epub 2016 Feb 4.

24.

Two clonal types of human skin fibroblasts with different potentials for proliferation and tissue remodeling ability.

Hiraoka C, Toki F, Shiraishi K, Sayama K, Nishimura EK, Miura H, Higashiyama S, Nanba D.

J Dermatol Sci. 2016 May;82(2):84-94. doi: 10.1016/j.jdermsci.2016.01.009. Epub 2016 Jan 29.

PMID:
26867959
25.

Enhanced glucose tolerance by intravascularly administered piceatannol in freely moving healthy rats.

Oritani Y, Okitsu T, Nishimura E, Sai M, Ito T, Takeuchi S.

Biochem Biophys Res Commun. 2016 Feb 12;470(3):753-758. doi: 10.1016/j.bbrc.2016.01.018. Epub 2016 Jan 7.

PMID:
26773506
26.

Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade.

Boothby TC, Tenlen JR, Smith FW, Wang JR, Patanella KA, Nishimura EO, Tintori SC, Li Q, Jones CD, Yandell M, Messina DN, Glasscock J, Goldstein B.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15976-81. doi: 10.1073/pnas.1510461112. Epub 2015 Nov 23. Erratum in: Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5364.

27.

Acromioclavicular dislocation: treatment and rehabilitation. Current perspectives and trends among Brazilian orthopedists.

Arliani GG, Utino AY, Nishimura EM, Terra BB, Belangero PS, Astur DC.

Rev Bras Ortop. 2015 Aug 18;50(5):515-22. doi: 10.1016/j.rboe.2015.08.003. eCollection 2015 Sep-Oct.

28.

Functional analyses of carnivorous plant-specific amino acid residues in S-like ribonucleases.

Arai N, Nishimura E, Kikuchi Y, Ohyama T.

Biochem Biophys Res Commun. 2015 Sep 11;465(1):108-12. doi: 10.1016/j.bbrc.2015.07.139. Epub 2015 Jul 30.

PMID:
26235877
29.

Rotation is the primary motion of paired human epidermal keratinocytes.

Tate S, Imai M, Matsushita N, Nishimura EK, Higashiyama S, Nanba D.

J Dermatol Sci. 2015 Sep;79(3):194-202. doi: 10.1016/j.jdermsci.2015.05.008. Epub 2015 Jun 10.

PMID:
26126707
30.

Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes.

Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Allen EJ, Donahue EP, Rivera N, Winnick JJ, Edgerton DS, Nishimura E, Fledelius C, Brand CL, Cherrington AD.

Diabetes. 2015 Oct;64(10):3439-51. doi: 10.2337/db15-0071. Epub 2015 Jun 17.

31.

Modified capsule expander implantation to reposition and fixate the capsular bag in eyes with subluxated cataractous lenses and phacodonesis: intermediate-term results.

Asano Y, Yaguchi S, Nishimura E, Soda M, Kozawa T.

J Cataract Refract Surg. 2015 Mar;41(3):598-606. doi: 10.1016/j.jcrs.2014.06.031. Epub 2015 Feb 21.

PMID:
25708209
32.
33.

Proteasome Inhibitor Bortezomib Enhances the Activity of Multiple Mutant Forms of Lysosomal α-Glucosidase in Pompe Disease.

Shimada Y, Nishimura E, Hoshina H, Kobayashi H, Higuchi T, Eto Y, Ida H, Ohashi T.

JIMD Rep. 2015;18:33-9. doi: 10.1007/8904_2014_345. Epub 2014 Sep 26.

34.

Open flow microperfusion: pharmacokinetics of human insulin and insulin detemir in the interstitial fluid of subcutaneous adipose tissue.

Höfferer C, Tutkur D, Fledelius C, Brand CL, Alsted TJ, Damgaard J, Nishimura E, Jeppesen CB, Mautner SI, Pieber TR, Sinner F.

Diabetes Obes Metab. 2015 Feb;17(2):121-7. doi: 10.1111/dom.12394. Epub 2014 Oct 26.

PMID:
25243522
35.

A melanocyte--melanoma precursor niche in sweat glands of volar skin.

Okamoto N, Aoto T, Uhara H, Yamazaki S, Akutsu H, Umezawa A, Nakauchi H, Miyachi Y, Saida T, Nishimura EK.

Pigment Cell Melanoma Res. 2014 Nov;27(6):1039-50. doi: 10.1111/pcmr.12297. Epub 2014 Sep 4.

PMID:
25065272
36.

Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog.

Edgerton DS, Moore MC, Winnick JJ, Scott M, Farmer B, Naver H, Jeppesen CB, Madsen P, Kjeldsen TB, Nishimura E, Brand CL, Cherrington AD.

Diabetes. 2014 Nov;63(11):3946-54. doi: 10.2337/db14-0266. Epub 2014 Jun 19.

37.

[I. Melanoma heterogeneity and cancer stem cell].

Nishimura EK.

Gan To Kagaku Ryoho. 2014 Apr;41(4):433-6. Japanese. No abstract available.

PMID:
24881088
38.

Structural and functional characteristics of S-like ribonucleases from carnivorous plants.

Nishimura E, Jumyo S, Arai N, Kanna K, Kume M, Nishikawa J, Tanase J, Ohyama T.

Planta. 2014 Jul;240(1):147-59. doi: 10.1007/s00425-014-2072-8. Epub 2014 Apr 26.

PMID:
24771022
39.

Coupling of the radiosensitivity of melanocyte stem cells to their dormancy during the hair cycle.

Ueno M, Aoto T, Mohri Y, Yokozeki H, Nishimura EK.

Pigment Cell Melanoma Res. 2014 Jul;27(4):540-51. doi: 10.1111/pcmr.12251. Epub 2014 May 27.

40.

Dietary exposure to phenolic and methoxylated organohalogen contaminants in relation to their concentrations in breast milk and serum in Japan.

Fujii Y, Nishimura E, Kato Y, Harada KH, Koizumi A, Haraguchi K.

Environ Int. 2014 Feb;63:19-25. doi: 10.1016/j.envint.2013.10.016. Epub 2013 Nov 19.

PMID:
24263137
41.

PP2A inhibition results in hepatic insulin resistance despite Akt2 activation.

Galbo T, Perry RJ, Nishimura E, Samuel VT, Quistorff B, Shulman GI.

Aging (Albany NY). 2013 Oct;5(10):770-81.

42.

Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice.

Omar BA, Andersen B, Hald J, Raun K, Nishimura E, Ahrén B.

Diabetes. 2014 Jan;63(1):101-10. doi: 10.2337/db13-0710. Epub 2013 Sep 23.

43.

Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.

Wittchen ES, Nishimura E, McCloskey M, Wang H, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME.

PLoS One. 2013 Sep 10;8(9):e73070. doi: 10.1371/journal.pone.0073070. eCollection 2013.

44.

S-like ribonuclease gene expression in carnivorous plants.

Nishimura E, Kawahara M, Kodaira R, Kume M, Arai N, Nishikawa J, Ohyama T.

Planta. 2013 Nov;238(5):955-67.

PMID:
23959189
45.

Usefulness of HPLC assay for early detection of microalbuminuria in chronic kidney disease.

Horikoshi S, Okuda M, Nishimura E, Ohsawa I, Suzuki Y, Shimizu Y, Hamada C, Tomino Y.

J Clin Lab Anal. 2013 Jul;27(4):333-8. doi: 10.1002/jcla.21608.

46.

Myopic refractive shift represents dense nuclear sclerosis and thin lens in lenticular myopia.

Cho YK, Huang W, Nishimura E.

Clin Exp Optom. 2013 Sep;96(5):479-85. doi: 10.1111/cxo.12064. Epub 2013 May 23.

47.

Accumulation of SNAP25 in mouse gustatory and somatosensory cortices in response to food and chemical stimulation.

Kawakami S, Ohmoto M, Itoh S, Yuasa R, Inagaki H, Nishimura E, Ito T, Misaka T.

Neuroscience. 2012 Aug 30;218:326-34. doi: 10.1016/j.neuroscience.2012.05.045. Epub 2012 May 26.

48.

International workshop: radiation effects on mutation in somatic and germline stem cells.

Kodama Y, Noda A, Booth C, Breault D, Suda T, Hendry J, Shinohara T, Rübe C, Nishimura EK, Mitani H, Nakamura N, Niwa O.

Int J Radiat Biol. 2012 Jun;88(6):501-6. doi: 10.3109/09553002.2012.683512. Epub 2012 May 4.

PMID:
22489999
49.

Photo-degradation products of pramipexole.

Nishimura E, Kugimiya A, Naoki H, Hamanaka N.

Bioorg Med Chem Lett. 2012 Apr 15;22(8):2951-3. doi: 10.1016/j.bmcl.2012.02.044. Epub 2012 Mar 1.

PMID:
22425455
50.

Systematic evaluation of the metabolic to mitogenic potency ratio for B10-substituted insulin analogues.

Glendorf T, Knudsen L, Stidsen CE, Hansen BF, Hegelund AC, Sørensen AR, Nishimura E, Kjeldsen T.

PLoS One. 2012;7(2):e29198. doi: 10.1371/journal.pone.0029198. Epub 2012 Feb 22.

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