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Items: 12

1.

Molecular and genetic basis of azole antifungal resistance in the opportunistic pathogenic fungus Candida albicans.

Nishimoto AT, Sharma C, Rogers PD.

J Antimicrob Chemother. 2019 Oct 11. pii: dkz400. doi: 10.1093/jac/dkz400. [Epub ahead of print]

PMID:
31603213
2.

Impact of the Major Candida glabrata Triazole Resistance Determinants on the Activity of the Novel Investigational Tetrazoles VT-1598 and VT-1161.

Nishimoto AT, Whaley SG, Wiederhold NP, Zhang Q, Yates CM, Hoekstra WJ, Schotzinger RJ, Garvey EP, Rogers PD.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e01304-19. doi: 10.1128/AAC.01304-19. Print 2019 Oct.

PMID:
31383660
3.

In Vitro Activities of the Novel Investigational Tetrazoles VT-1161 and VT-1598 Compared to the Triazole Antifungals against Azole-Resistant Strains and Clinical Isolates of Candida albicans.

Nishimoto AT, Wiederhold NP, Flowers SA, Zhang Q, Kelly SL, Morschhäuser J, Yates CM, Hoekstra WJ, Schotzinger RJ, Garvey EP, Rogers PD.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00341-19. doi: 10.1128/AAC.00341-19. Print 2019 Jun.

PMID:
30910896
4.

A Systematic Screen Reveals a Diverse Collection of Medications That Induce Antifungal Resistance in Candida Species.

Butts A, Reitler P, Nishimoto AT, DeJarnette C, Estredge LR, Peters TL, Veve MP, Rogers PD, Palmer GE.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00054-19. doi: 10.1128/AAC.00054-19. Print 2019 May.

PMID:
30858206
5.

Contribution of Clinically Derived Mutations in the Gene Encoding the Zinc Cluster Transcription Factor Mrr2 to Fluconazole Antifungal Resistance and CDR1 Expression in Candida albicans.

Nishimoto AT, Zhang Q, Hazlett B, Morschhäuser J, Rogers PD.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00078-19. doi: 10.1128/AAC.00078-19. Print 2019 May.

PMID:
30833425
6.

The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions.

Warrilow AG, Nishimoto AT, Parker JE, Price CL, Flowers SA, Kelly DE, Rogers PD, Kelly SL.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02586-18. doi: 10.1128/AAC.02586-18. Print 2019 May.

7.

Abrogation of Triazole Resistance upon Deletion of CDR1 in a Clinical Isolate of Candida auris.

Rybak JM, Doorley LA, Nishimoto AT, Barker KS, Palmer GE, Rogers PD.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e00057-19. doi: 10.1128/AAC.00057-19. Print 2019 Apr.

8.

Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity.

Luna-Tapia A, Willems HME, Parker JE, Tournu H, Barker KS, Nishimoto AT, Rogers PD, Kelly SL, Peters BM, Palmer GE.

MBio. 2018 May 22;9(3). pii: e00225-18. doi: 10.1128/mBio.00225-18.

9.

Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis.

Rybak JM, Dickens CM, Parker JE, Caudle KE, Manigaba K, Whaley SG, Nishimoto AT, Luna-Tapia A, Roy S, Zhang Q, Barker KS, Palmer GE, Sutter TR, Homayouni R, Wiederhold NP, Kelly SL, Rogers PD.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00651-17. doi: 10.1128/AAC.00651-17. Print 2017 Sep.

10.

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species.

Whaley SG, Berkow EL, Rybak JM, Nishimoto AT, Barker KS, Rogers PD.

Front Microbiol. 2017 Jan 12;7:2173. doi: 10.3389/fmicb.2016.02173. eCollection 2016. Review.

11.

Isavuconazole: Pharmacology, Pharmacodynamics, and Current Clinical Experience with a New Triazole Antifungal Agent.

Rybak JM, Marx KR, Nishimoto AT, Rogers PD.

Pharmacotherapy. 2015 Nov;35(11):1037-51. doi: 10.1002/phar.1652. Epub 2015 Nov 2. Review.

PMID:
26598096
12.

20-Hydroxyeicosatetraenoic acid mediates angiotensin ii-induced phospholipase d activation in vascular smooth muscle cells.

Parmentier JH, Muthalif MM, Nishimoto AT, Malik KU.

Hypertension. 2001 Feb;37(2 Pt 2):623-9.

PMID:
11230346

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