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Items: 11

1.

Route-dependent nonlinear pharmacokinetics of a novel HIV protease inhibitor: involvement of enzyme inactivation.

Lin JH, Chen IW, Chiba M, Nishime JA, Deluna FA.

Drug Metab Dispos. 2000 Apr;28(4):460-6.

PMID:
10725315
2.

Comparative in vitro metabolism of indinavir in primates--a unique stereoselective hydroxylation in monkey.

Chiba M, Nishime JA, Neway W, Lin Y, Lin JH.

Xenobiotica. 2000 Feb;30(2):117-29.

PMID:
10718120
3.

Effect of dexamethasone on the intestinal first-pass metabolism of indinavir in rats: evidence of cytochrome P-450 3A [correction of P-450 A] and p-glycoprotein induction .

Lin JH, Chiba M, Chen IW, Nishime JA, deLuna FA, Yamazaki M, Lin YJ.

Drug Metab Dispos. 1999 Oct;27(10):1187-93. Erratum in: Drug Metab Dispos 1999 Nov;27(11):1374.

PMID:
10497146
4.

Modulation of rat cytochrome P-450 by an investigational HIV protease inhibitor.

Nishime JA, Wang RW, Lin JH, Chiba M.

Drug Metab Dispos. 1999 Sep;27(9):972-6.

PMID:
10460793
5.

Metabolite-P450 complex formation by methylenedioxyphenyl HIV protease inhibitors in rat and human liver microsomes.

Chiba M, Nishime JA, Chen IW, Vastag KJ, Sahly YS, Kim BM, Dorsey BD, Vacca JP, Lin JH.

Biochem Pharmacol. 1998 Jul 15;56(2):223-30.

PMID:
9698076
6.

Hepatic microsomal metabolism of montelukast, a potent leukotriene D4 receptor antagonist, in humans.

Chiba M, Xu X, Nishime JA, Balani SK, Lin JH.

Drug Metab Dispos. 1997 Sep;25(9):1022-31.

PMID:
9311616
7.

Sex-dependent pharmacokinetics of indinavir: in vivo and in vitro evidence.

Lin JH, Chiba M, Chen IW, Nishime JA, Vastag KJ.

Drug Metab Dispos. 1996 Dec;24(12):1298-306.

PMID:
8971134
8.

Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor.

Lin JH, Chiba M, Balani SK, Chen IW, Kwei GY, Vastag KJ, Nishime JA.

Drug Metab Dispos. 1996 Oct;24(10):1111-20.

PMID:
8894513
9.

Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.

Chiba M, Hensleigh M, Nishime JA, Balani SK, Lin JH.

Drug Metab Dispos. 1996 Mar;24(3):307-14.

PMID:
8820421
11.

Time- and dose-dependent pharmacokinetics of L-754,394, an HIV protease inhibitor, in rats, dogs and monkeys.

Lin JH, Chiba M, Chen IW, Vastag KJ, Nishime JA, Dorsey BD, Michelson SR, McDaniel SL.

J Pharmacol Exp Ther. 1995 Jul;274(1):264-9.

PMID:
7616407

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