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Items: 1 to 50 of 154

1.

Variable Selection for Nonparametric Learning with Power Series Kernels.

Matsui K, Kumagai W, Kanamori K, Nishikimi M, Kanamori T.

Neural Comput. 2019 Aug;31(8):1718-1750. doi: 10.1162/neco_a_01212. Epub 2019 Jul 1.

PMID:
31260393
2.

A Progressive Early Mobilization Program Is Significantly Associated With Clinical and Economic Improvement: A Single-Center Quality Comparison Study.

Liu K, Ogura T, Takahashi K, Nakamura M, Ohtake H, Fujiduka K, Abe E, Oosaki H, Miyazaki D, Suzuki H, Nishikimi M, Komatsu M, Lefor AK, Mato T.

Crit Care Med. 2019 Sep;47(9):e744-e752. doi: 10.1097/CCM.0000000000003850.

PMID:
31162197
3.

External validation of a risk classification at the emergency department of post-cardiac arrest syndrome patients undergoing targeted temperature management.

Nishikimi M, Ogura T, Nishida K, Takahashi K, Nakamura M, Matsui S, Matsuda N, Iwami T.

Resuscitation. 2019 Jul;140:135-141. doi: 10.1016/j.resuscitation.2019.05.028. Epub 2019 May 30.

PMID:
31153943
4.

Timing of administration of epinephrine predicts the responsiveness to epinephrine in norepinephrine-refractory septic shock: a retrospective study.

Kasugai D, Nishikimi M, Nishida K, Higashi M, Yamamoto T, Numaguchi A, Takahashi K, Matsui S, Matsuda N.

J Intensive Care. 2019 Apr 5;7:20. doi: 10.1186/s40560-019-0377-1. eCollection 2019.

5.

Challenges and Inconsistencies in Using Lysophosphatidic Acid as a Biomarker for Ovarian Cancer.

Yagi T, Shoaib M, Kuschner C, Nishikimi M, Becker LB, Lee AT, Kim J.

Cancers (Basel). 2019 Apr 11;11(4). pii: E520. doi: 10.3390/cancers11040520.

6.

The authors reply.

Nishikimi M, Numaguchi A, Takahashi K, Matsui S, Matsuda N.

Crit Care Med. 2018 Dec;46(12):e1225-e1226. doi: 10.1097/CCM.0000000000003452. No abstract available.

PMID:
30444825
7.

The authors reply.

Nishikimi M, Numaguchi A, Takahashi K, Matsui S, Matsuda N.

Crit Care Med. 2018 Oct;46(10):e1010-e1011. doi: 10.1097/CCM.0000000000003315. No abstract available.

PMID:
30216316
8.

Accuracy of the first interpretation of early brain CT images for predicting the prognosis of post-cardiac arrest syndrome patients at the emergency department.

Nishikimi M, Ogura T, Matsui K, Takahashi K, Fukaya K, Liu K, Morita H, Nakamura M, Matsui S, Matsuda N.

J Intensive Care. 2018 Apr 25;6:26. doi: 10.1186/s40560-018-0296-6. eCollection 2018.

9.

Differential effect of mild therapeutic hypothermia depending on the findings of hypoxic encephalopathy on early CT images in patients with post-cardiac arrest syndrome.

Nishikimi M, Ogura T, Nishida K, Takahashi K, Fukaya K, Liu K, Nakamura M, Matsui S, Matsuda N.

Resuscitation. 2018 Jul;128:11-15. doi: 10.1016/j.resuscitation.2018.04.029. Epub 2018 Apr 23.

PMID:
29698752
10.

Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial.

Nishikimi M, Numaguchi A, Takahashi K, Miyagawa Y, Matsui K, Higashi M, Makishi G, Matsui S, Matsuda N.

Crit Care Med. 2018 Jul;46(7):1099-1105. doi: 10.1097/CCM.0000000000003132.

11.

The safety of a novel early mobilization protocol conducted by ICU physicians: a prospective observational study.

Liu K, Ogura T, Takahashi K, Nakamura M, Ohtake H, Fujiduka K, Abe E, Oosaki H, Miyazaki D, Suzuki H, Nishikimi M, Lefor AK, Mato T.

J Intensive Care. 2018 Feb 20;6:10. doi: 10.1186/s40560-018-0281-0. eCollection 2018.

12.

A novel scoring system for predicting the neurologic prognosis prior to the initiation of induced hypothermia in cases of post-cardiac arrest syndrome: the CAST score.

Nishikimi M, Matsuda N, Matsui K, Takahashi K, Ejima T, Liu K, Ogura T, Higashi M, Umino H, Makishi G, Numaguchi A, Matsushima S, Tokuyama H, Nakamura M, Matsui S.

Scand J Trauma Resusc Emerg Med. 2017 May 10;25(1):49. doi: 10.1186/s13049-017-0392-y.

13.

CAST: a new score for early prediction of neurological outcomes after cardiac arrest before therapeutic hypothermia with high accuracy.

Nishikimi M, Matsuda N, Matsui K, Takahashi K, Ejima T, Liu K, Ogura T, Higashi M, Umino H, Makishi G, Numaguchi A, Matsushima S, Tokuyama H, Nakamura M, Matsui S.

Intensive Care Med. 2016 Dec;42(12):2106-2107. doi: 10.1007/s00134-016-4492-3. Epub 2016 Aug 16. No abstract available.

14.

Axon guidance mechanisms for establishment of callosal connections.

Nishikimi M, Oishi K, Nakajima K.

Neural Plast. 2013;2013:149060. doi: 10.1155/2013/149060. Epub 2013 Feb 24. Review.

15.

In vivo role of aldehyde reductase.

Takahashi M, Miyata S, Fujii J, Inai Y, Ueyama S, Araki M, Soga T, Fujinawa R, Nishitani C, Ariki S, Shimizu T, Abe T, Ihara Y, Nishikimi M, Kozutsumi Y, Taniguchi N, Kuroki Y.

Biochim Biophys Acta. 2012 Nov;1820(11):1787-96. doi: 10.1016/j.bbagen.2012.07.003. Epub 2012 Jul 20.

PMID:
22820017
16.

Segregation and pathfinding of callosal axons through EphA3 signaling.

Nishikimi M, Oishi K, Tabata H, Torii K, Nakajima K.

J Neurosci. 2011 Nov 9;31(45):16251-60. doi: 10.1523/JNEUROSCI.3303-11.2011.

17.

Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice.

Furusawa H, Sato Y, Tanaka Y, Inai Y, Amano A, Iwama M, Kondo Y, Handa S, Murata A, Nishikimi M, Goto S, Maruyama N, Takahashi R, Ishigami A.

Biol Pharm Bull. 2008 Sep;31(9):1673-9.

18.

Combination of NADPH and copper ions generates proteinase K-resistant aggregates from recombinant prion protein.

Shiraishi N, Utsunomiya H, Nishikimi M.

J Biol Chem. 2006 Nov 17;281(46):34880-7. Epub 2006 Sep 21.

19.

Senescence marker protein 30 functions as gluconolactonase in L-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy.

Kondo Y, Inai Y, Sato Y, Handa S, Kubo S, Shimokado K, Goto S, Nishikimi M, Maruyama N, Ishigami A.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5723-8. Epub 2006 Apr 3.

20.

Enhanced oxidative stress by L-ascorbic acid within cells challenged by hydrogen peroxide.

Inai Y, Bi W, Shiraishi N, Nishikimi M.

J Nutr Sci Vitaminol (Tokyo). 2005 Dec;51(6):398-405.

PMID:
16521698
21.

Fragmentation and dimerization of copper-loaded prion protein by copper-catalysed oxidation.

Shiraishi N, Inai Y, Bi W, Nishikimi M.

Biochem J. 2005 Apr 1;387(Pt 1):247-55.

23.

Impaired ascorbic acid metabolism in streptozotocin-induced diabetic rats.

Kashiba M, Oka J, Ichikawa R, Kasahara E, Inayama T, Kageyama A, Kageyama H, Osaka T, Umegaki K, Matsumoto A, Ishikawa T, Nishikimi M, Inoue M, Inoue S.

Free Radic Biol Med. 2002 Nov 1;33(9):1221-30.

PMID:
12398930
24.

Increased degradation of oxidized proteins in yeast defective in 26 S proteasome assembly.

Inai Y, Nishikimi M.

Arch Biochem Biophys. 2002 Aug 15;404(2):279-84.

PMID:
12147266
25.
26.

Ascorbate-induced high-affinity binding of copper to cytosolic proteins.

Ohta Y, Shiraishi N, Inai Y, Lee IS, Iwahashi H, Nishikimi M.

Biochem Biophys Res Commun. 2001 Oct 5;287(4):888-94.

PMID:
11573948
27.

Impaired reductive regeneration of ascorbic acid in the Goto-Kakizaki diabetic rat.

Kashiba M, Oka J, Ichikawa R, Kageyama A, Inayama T, Kageyama H, Ishikawa T, Nishikimi M, Inoue M, Inoue S.

Biochem J. 2000 Oct 15;351 Pt 2:313-8.

28.

Copper-catalyzed autoxidations of GSH and L-ascorbic acid: mutual inhibition of the respective oxidations by their coexistence.

Ohta Y, Shiraishi N, Nishikawa T, Nishikimi M.

Biochim Biophys Acta. 2000 May 1;1474(3):378-82.

PMID:
10779690
29.

Copper-dependent formation of disulfide-linked dimer of S100B protein.

Matsui Lee IS, Suzuki M, Hayashi N, Hu J, Van Eldik LJ, Titani K, Nishikimi M.

Arch Biochem Biophys. 2000 Feb 15;374(2):137-41.

PMID:
10666291
30.

The octapeptide repeat region of prion protein binds Cu(II) in the redox-inactive state.

Shiraishi N, Ohta Y, Nishikimi M.

Biochem Biophys Res Commun. 2000 Jan 7;267(1):398-402.

PMID:
10623631
31.
32.

Specific expression of alanine-glyoxylate aminotransferase 2 in the epithelial cells of Henle's loop.

Lee IS, Nishikimi M, Inoue M, Muragaki Y, Ooshima A.

Nephron. 1999;83(2):184-5. No abstract available.

PMID:
10516509
33.

Calcium-dependent interaction between the large myelin-associated glycoprotein and S100beta.

Kursula P, Tikkanen G, Lehto VP, Nishikimi M, Heape AM.

J Neurochem. 1999 Oct;73(4):1724-32.

34.

Basic study on gene therapy of human malignant glioma by use of the cationic multilamellar liposome-entrapped human interferon beta gene.

Yagi K, Ohishi N, Hamada A, Shamoto M, Ohbayashi M, Ishida N, Nagata A, Kanazawa S, Nishikimi M.

Hum Gene Ther. 1999 Aug 10;10(12):1975-82.

PMID:
10466631
35.

Molecular cloning and functional expression of rat liver glutathione-dependent dehydroascorbate reductase.

Ishikawa T, Casini AF, Nishikimi M.

J Biol Chem. 1998 Oct 30;273(44):28708-12.

36.

Suppression of copper-induced cellular damage by copper sequestration with S100b protein.

Shiraishi N, Nishikimi M.

Arch Biochem Biophys. 1998 Sep 15;357(2):225-30.

PMID:
9735162
37.
38.

Increased cellular resistance to oxidative stress by expression of cyanobacterium catalase-peroxidase in animal cells.

Ishikawa T, Ohta Y, Takeda T, Shigeoka S, Nishikimi M.

FEBS Lett. 1998 Apr 17;426(2):221-4.

39.

Occurrence of two missense mutations in Cu-ATPase of the macular mouse, a Menkes disease model.

Ohta Y, Shiraishi N, Nishikimi M.

Biochem Mol Biol Int. 1997 Nov;43(4):913-8.

PMID:
9385451
40.

Identification of S100b protein as copper-binding protein and its suppression of copper-induced cell damage.

Nishikawa T, Lee IS, Shiraishi N, Ishikawa T, Ohta Y, Nishikimi M.

J Biol Chem. 1997 Sep 12;272(37):23037-41.

41.

Expression of recombinant L-gulono-gamma-lactone oxidase.

Yagi K, Nishikimi M.

Methods Enzymol. 1997;279:24-9. Review. No abstract available.

PMID:
9211253
42.

Transgenic expression of L-gulono-gamma-lactone oxidase in medaka (Oryzias latipes), a teleost fish that lacks this enzyme necessary for L-ascorbic acid biosynthesis.

Toyohara H, Nakata T, Touhata K, Hashimoto H, Kinoshita M, Sakaguchi M, Nishikimi M, Yagi K, Wakamatsu Y, Ozato K.

Biochem Biophys Res Commun. 1996 Jun 25;223(3):650-3.

PMID:
8687450
43.

[Recent advance in the study of ascorbic acid biosynthesis].

Nishikimi M.

Seikagaku. 1996 May;68(5):377-80. Japanese. No abstract available.

PMID:
8727663
44.

Expression of human phospholipid hydroperoxide glutathione peroxidase gene for protection of host cells from lipid hydroperoxide-mediated injury.

Yagi K, Komura S, Kojima H, Sun Q, Nagata N, Ohishi N, Nishikimi M.

Biochem Biophys Res Commun. 1996 Feb 15;219(2):486-91.

PMID:
8605014
45.

Biochemistry and molecular biology of ascorbic acid biosynthesis.

Nishikimi M, Yagi K.

Subcell Biochem. 1996;25:17-39. Review. No abstract available.

PMID:
8821967
46.
47.
48.

Sequential deletion of DNA by use of remodeled pUC18 and pUC19 vectors.

Nishikimi M, Yagi K.

Biochem Mol Biol Int. 1993 Oct;31(2):359-63.

PMID:
8275024
49.

L-gulono-gamma-lactone oxidase is not induced in rats by xenobiotics stimulating L-ascorbic acid biosynthesis.

Horio F, Shibata T, Naito Y, Nishikimi M, Yagi K, Yoshida A.

J Nutr Sci Vitaminol (Tokyo). 1993 Feb;39(1):1-9.

PMID:
8509896
50.

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