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Items: 43


Activation of the DR3-TL1A Axis in Donor Mice Leads to Regulatory T Cell Expansion and Activation With Reduction in Graft-Versus-Host Disease.

Mavers M, Simonetta F, Nishikii H, Ribado JV, Maas-Bauer K, Alvarez M, Hirai T, Turkoz M, Baker J, Negrin RS.

Front Immunol. 2019 Jul 17;10:1624. doi: 10.3389/fimmu.2019.01624. eCollection 2019.


Notch Signaling in Nestin-Expressing Cells in the Bone Marrow Maintains Erythropoiesis via Macrophage Integrity.

Sakamoto T, Obara N, Nishikii H, Kato T, Cao-Sy L, Fujimura R, Yagita H, Sakata-Yanagimoto M, Takahashi S, Chiba S.

Stem Cells. 2019 Jul;37(7):924-936. doi: 10.1002/stem.3011. Epub 2019 Apr 15.


[Successful management of primary immune thrombocytopenia with romiplostim during open heart surgery in a hemodialysis patient].

Nishikii H, Kurita N, Kusakabe M, Yokoyama Y, Kato T, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S.

Rinsho Ketsueki. 2019;60(1):28-32. doi: 10.11406/rinketsu.60.28. Japanese.


Durable Leukemic Remission and Autologous Marrow Recovery with Random Chromosomal Abnormalities after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia.

Nishikii H, Kurita N, Shinagawa A, Sakamoto T, Kusakabe M, Yokoyama Y, Kato T, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Nakamura N, Chiba S.

Case Rep Hematol. 2019 Jan 3;2019:9710790. doi: 10.1155/2019/9710790. eCollection 2019.


Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis.

Cao-Sy L, Obara N, Sakamoto T, Kato T, Hattori K, Sakashita S, Nannya Y, Ogawa S, Harada H, Sakata-Yanagimoto M, Nishikii H, Chiba S.

Int J Hematol. 2019 Mar;109(3):309-318. doi: 10.1007/s12185-018-02576-9. Epub 2019 Jan 10.


[Blastic plasmacytoid dendritic cell neoplasm accompanied by chronic myelomonocytic leukemia successfully treated with azacitidine].

Sukegawa S, Sakata-Yanagimoto M, Matsuoka R, Momose H, Kiyoki Y, Noguchi M, Nakamura N, Watanabe R, Fujimoto M, Yokoyama Y, Nishikii H, Kato T, Kusakabe M, Kurita N, Obara N, Hasegawa Y, Chiba S.

Rinsho Ketsueki. 2018;59(12):2567-2573. doi: 10.11406/rinketsu.59.2567. Japanese.


The prognosis of disseminated intravascular coagulation associated with hematologic malignancy and its response to recombinant human thrombomodulin.

Kurita N, Sakamoto T, Kato T, Kusakabe M, Yokoyama Y, Nishikii H, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S.

Thromb Res. 2019 Jan;173:57-64. doi: 10.1016/j.thromres.2018.11.014. Epub 2018 Nov 16.


An Unprecedented Case of p190 BCR-ABL Chronic Myeloid Leukemia Diagnosed during Treatment for Multiple Myeloma: A Case Report and Review of the Literature.

Miki K, Obara N, Makishima K, Sakamoto T, Kusakabe M, Kato T, Kurita N, Nishikii H, Yokoyama Y, Sakata-Yanagimoto M, Hasegawa Y, Chiba S.

Case Rep Hematol. 2018 Oct 10;2018:7863943. doi: 10.1155/2018/7863943. eCollection 2018.


Genetic evidence implies that primary and relapsed tumors arise from common precursor cells in primary central nervous system lymphoma.

Hattori K, Sakata-Yanagimoto M, Kusakabe M, Nanmoku T, Suehara Y, Matsuoka R, Noguchi M, Yokoyama Y, Kato T, Kurita N, Nishikii H, Obara N, Takano S, Ishikawa E, Matsumura A, Muratani M, Hasegawa Y, Chiba S.

Cancer Sci. 2019 Jan;110(1):401-407. doi: 10.1111/cas.13848. Epub 2018 Nov 18.


High efficacy of eculizumab treatment for fulminant hemolytic anemia in primary cold agglutinin disease.

Makishima K, Obara N, Ishitsuka K, Sukegawa S, Suma S, Kiyoki Y, Baba N, Sakamoto T, Kato T, Kusakabe M, Nishikii H, Kurita N, Yokoyama Y, Sakata-Yanagimoto M, Hasegawa Y, Chiba S.

Ann Hematol. 2019 Apr;98(4):1031-1032. doi: 10.1007/s00277-018-3521-4. Epub 2018 Oct 15. No abstract available.


SINC-seq: correlation of transient gene expressions between nucleus and cytoplasm reflects single-cell physiology.

Abdelmoez MN, Iida K, Oguchi Y, Nishikii H, Yokokawa R, Kotera H, Uemura S, Santiago JG, Shintaku H.

Genome Biol. 2018 Jun 6;19(1):66. doi: 10.1186/s13059-018-1446-9.


Blastic plasmacytoid dendritic cell neoplasm arising from clonal hematopoiesis.

Suma S, Sakata-Yanagimoto M, Nguyen TB, Hattori K, Sato T, Noguchi M, Nannya Y, Ogawa S, Watanabe R, Fujimoto M, Nakamura N, Kusakabe M, Nishikii H, Kato T, Chiba S.

Int J Hematol. 2018 Oct;108(4):447-451. doi: 10.1007/s12185-018-2461-z. Epub 2018 Apr 28.


Liquid biopsy for the identification of intravascular large B-cell lymphoma.

Suehara Y, Sakata-Yanagimoto M, Hattori K, Nanmoku T, Itoh T, Kaji D, Yamamoto G, Abe Y, Narita K, Takeuchi M, Matsue K, Sato T, Noguchi M, Baba N, Sakamoto T, Kusakabe M, Kurita N, Kato T, Yokoyama Y, Nishikii H, Obara N, Hasegawa Y, Chiba S.

Haematologica. 2018 Jun;103(6):e241-e244. doi: 10.3324/haematol.2017.178830. Epub 2018 Feb 22. No abstract available.


Clinical significance of disease-specific MYD88 mutations in circulating DNA in primary central nervous system lymphoma.

Hattori K, Sakata-Yanagimoto M, Suehara Y, Yokoyama Y, Kato T, Kurita N, Nishikii H, Obara N, Takano S, Ishikawa E, Matsumura A, Hasegawa Y, Chiba S.

Cancer Sci. 2018 Jan;109(1):225-230. doi: 10.1111/cas.13450. Epub 2017 Dec 23.


The Road Map for Megakaryopoietic Lineage from Hematopoietic Stem/Progenitor Cells.

Nishikii H, Kurita N, Chiba S.

Stem Cells Transl Med. 2017 Aug;6(8):1661-1665. doi: 10.1002/sctm.16-0490. Epub 2017 Jul 6. Review.


Haploidentical transplantation using post-transplant high-dose cyclophosphamide for adult T-cell lymphoma after mogamulizumab treatment.

Kusakabe M, Kurita N, Nishikii H, Sato R, Yoshida C, Yokoyama Y, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S.

Rinsho Ketsueki. 2017;58(5):449-454. doi: 10.11406/rinketsu.58.449. Review. Japanese.


A PET Imaging Strategy to Visualize Activated T Cells in Acute Graft-versus-Host Disease Elicited by Allogenic Hematopoietic Cell Transplant.

Ronald JA, Kim BS, Gowrishankar G, Namavari M, Alam IS, D'Souza A, Nishikii H, Chuang HY, Ilovich O, Lin CF, Reeves R, Shuhendler A, Hoehne A, Chan CT, Baker J, Yaghoubi SS, VanBrocklin HF, Hawkins R, Franc BL, Jivan S, Slater JB, Verdin EF, Gao KT, Benjamin J, Negrin R, Gambhir SS.

Cancer Res. 2017 Jun 1;77(11):2893-2902. doi: 10.1158/0008-5472.CAN-16-2953.


Foxp3+ regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis.

Pierini A, Nishikii H, Baker J, Kimura T, Kwon HS, Pan Y, Chen Y, Alvarez M, Strober W, Velardi A, Shizuru JA, Wu JY, Chiba S, Negrin RS.

Nat Commun. 2017 May 9;8:15068. doi: 10.1038/ncomms15068.


DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.

Nishikii H, Kim BS, Yokoyama Y, Chen Y, Baker J, Pierini A, Alvarez M, Mavers M, Maas-Bauer K, Pan Y, Chiba S, Negrin RS.

Blood. 2016 Dec 15;128(24):2846-2858. Epub 2016 Oct 19.


Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán-Garrote AL, Bäuerlein CA, Brede C, Ribechini E, Fick A, Seher A, Polz J, Ottmüller KJ, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Müller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A.

J Exp Med. 2016 Aug 22;213(9):1881-900. doi: 10.1084/jem.20151563. Epub 2016 Aug 15.


TNF-α priming enhances CD4+FoxP3+ regulatory T-cell suppressive function in murine GVHD prevention and treatment.

Pierini A, Strober W, Moffett C, Baker J, Nishikii H, Alvarez M, Pan Y, Schneidawind D, Meyer E, Negrin RS.

Blood. 2016 Aug 11;128(6):866-71. doi: 10.1182/blood-2016-04-711275. Epub 2016 Jun 30.


Regulatory T Cell Immunotherapy in Immune-Mediated Diseases.

Pierini A, Schneidawind D, Nishikii H, Negrin RS.

Curr Stem Cell Rep. 2015 Dec 1;1(4):177-186. Epub 2015 Sep 12.


Treatment with agonistic DR3 antibody results in expansion of donor Tregs and reduced graft-versus-host disease.

Kim BS, Nishikii H, Baker J, Pierini A, Schneidawind D, Pan Y, Beilhack A, Park CG, Negrin RS.

Blood. 2015 Jul 23;126(4):546-57. doi: 10.1182/blood-2015-04-637587. Epub 2015 Jun 10.


Donor Requirements for Regulatory T Cell Suppression of Murine Graft-versus-Host Disease.

Pierini A, Colonna L, Alvarez M, Schneidawind D, Nishikii H, Baker J, Pan Y, Florek M, Kim BS, Negrin RS.

J Immunol. 2015 Jul 1;195(1):347-55. doi: 10.4049/jimmunol.1402861. Epub 2015 May 20.


Engraftment of embryonic stem cells and differentiated progeny by host conditioning with total lymphoid irradiation and regulatory T cells.

Pan Y, Leveson-Gower DB, de Almeida PE, Pierini A, Baker J, Florek M, Nishikii H, Kim BS, Ke R, Wu JC, Negrin RS.

Cell Rep. 2015 Mar 24;10(11):1793-802.


Unipotent Megakaryopoietic Pathway Bridging Hematopoietic Stem Cells and Mature Megakaryocytes.

Nishikii H, Kanazawa Y, Umemoto T, Goltsev Y, Matsuzaki Y, Matsushita K, Yamato M, Nolan GP, Negrin R, Chiba S.

Stem Cells. 2015 Jul;33(7):2196-207. doi: 10.1002/stem.1985. Epub 2015 Apr 27.


Hes1 suppresses acute myeloid leukemia development through FLT3 repression.

Kato T, Sakata-Yanagimoto M, Nishikii H, Ueno M, Miyake Y, Yokoyama Y, Asabe Y, Kamada Y, Muto H, Obara N, Suzukawa K, Hasegawa Y, Kitabayashi I, Uchida K, Hirao A, Yagita H, Kageyama R, Chiba S.

Leukemia. 2015 Mar;29(3):576-85. doi: 10.1038/leu.2014.281. Epub 2014 Sep 19.


On-chip separation and analysis of RNA and DNA from single cells.

Shintaku H, Nishikii H, Marshall LA, Kotera H, Santiago JG.

Anal Chem. 2014 Feb 18;86(4):1953-7. doi: 10.1021/ac4040218. Epub 2014 Feb 5.


[Acute myeloid leukemia possibly originating from the same clone of testicular germ cell tumor].

Suyama T, Obara N, Kawai K, Yamada K, Kusakabe M, Kurita N, Nishikii H, Yokoyama Y, Suzukawa K, Hasegawa Y, Noguchi M, Chiba S.

Rinsho Ketsueki. 2013 Aug;54(8):764-8. Japanese.


Effectiveness and safety of rabbit anti-thymocyte globulin in Japanese patients with aplastic anemia.

Sakamoto T, Obara N, Kurita N, Sakata-Yanagimoto M, Nishikii H, Yokoyama Y, Suzukawa K, Hasegawa Y, Chiba S.

Int J Hematol. 2013 Sep;98(3):319-22. doi: 10.1007/s12185-013-1418-5. Epub 2013 Aug 21.


Perisurgical induction of eculizumab in a patient with paroxysmal nocturnal hemoglobinuria: its inhibition of surgery-triggered hemolysis and the consequence of subsequent discontinuation.

Kurita N, Obara N, Fukuda K, Nishikii H, Sato S, Inagawa S, Kurokawa T, Owada Y, Ninomiya H, Chiba S.

Blood Coagul Fibrinolysis. 2013 Sep;24(6):658-62. doi: 10.1097/MBC.0b013e328360d057.


Post-transplant gastric antral vascular ectasia after intra-venous busulfan regimen.

Fukuda K, Kurita N, Sakamoto T, Nishikii H, Okoshi Y, Sugano M, Chiba S.

Int J Hematol. 2013 Jul;98(1):135-8. doi: 10.1007/s12185-013-1342-8. Epub 2013 Apr 30.


MYC rearrangements are useful for predicting outcomes following rituximab and chemotherapy: multicenter analysis of Japanese patients with diffuse large B-cell lymphoma.

Kojima M, Nishikii H, Takizawa J, Aoki S, Noguchi M, Chiba S, Ando K, Nakamura N.

Leuk Lymphoma. 2013 Oct;54(10):2149-54. doi: 10.3109/10428194.2013.771398. Epub 2013 Mar 8.


Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis.

Kamada Y, Sakata-Yanagimoto M, Sanada M, Sato-Otsubo A, Enami T, Suzukawa K, Kurita N, Nishikii H, Yokoyama Y, Okoshi Y, Hasegawa Y, Ogawa S, Chiba S.

Int J Hematol. 2012 Oct;96(4):492-500. doi: 10.1007/s12185-012-1171-1. Epub 2012 Sep 13.


Early pathologic findings of bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation: a proposal from a case.

Nakamoto-Matsubara R, Nishikii H, Yamada K, Ito M, Hasegawa Y, Kurita N, Obara N, Okoshi Y, Suzukawa K, Yokoyama Y, Sakata-Yanagimoto M, Noguchi M, Chiba S.

Case Rep Hematol. 2012;2012:957612. doi: 10.1155/2012/957612. Epub 2012 Aug 22.


Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice.

Yoh K, Morito N, Ojima M, Shibuya K, Yamashita Y, Morishima Y, Ishii Y, Kusakabe M, Nishikii H, Fujita A, Matsunaga E, Okamura M, Hamada M, Suto A, Nakajima H, Shibuya A, Yamagata K, Takahashi S.

Eur J Immunol. 2012 Aug;42(8):1999-2009. doi: 10.1002/eji.201142250. Epub 2012 Jul 9.


Treatment outcome of adult Burkitt Lymphoma in Japanese patients with modified LMB protocol : a single center retrospective analysis.

Nishikii H, Nakamura N, Kondo Y, Okoshi Y, Suzukawa K, Hasegawa Y, Yokoyama Y, Sakata-Yanagimoto M, Enami T, Noguchi M, Chiba S.

J Clin Exp Hematop. 2011;51(2):109-14.


Human immunodeficiency virus-associated Burkitt's lymphoma in oral cavity of Japanese patient.

Goto M, Onizawa K, Yanagawa T, Yamagata K, Shinozuka K, Nishikii H, Koganemaru H, Chiba S, Bukawa H.

J Oral Maxillofac Surg. 2012 Aug;70(8):1885-90. doi: 10.1016/j.joms.2011.08.015. Epub 2011 Nov 10. No abstract available.


Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo.

Takizawa H, Nishimura S, Takayama N, Oda A, Nishikii H, Morita Y, Kakinuma S, Yamazaki S, Okamura S, Tamura N, Goto S, Sawaguchi A, Manabe I, Takatsu K, Nakauchi H, Takaki S, Eto K.

J Clin Invest. 2010 Jan;120(1):179-90. doi: 10.1172/JCI39503. Epub 2009 Dec 21.


Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells.

Nishikii H, Eto K, Tamura N, Hattori K, Heissig B, Kanaji T, Sawaguchi A, Goto S, Ware J, Nakauchi H.

J Exp Med. 2008 Aug 4;205(8):1917-27. doi: 10.1084/jem.20071482. Epub 2008 Jul 28.


Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors.

Takayama N, Nishikii H, Usui J, Tsukui H, Sawaguchi A, Hiroyama T, Eto K, Nakauchi H.

Blood. 2008 Jun 1;111(11):5298-306. doi: 10.1182/blood-2007-10-117622. Epub 2008 Apr 3.


The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.

Eto K, Nishikii H, Ogaeri T, Suetsugu S, Kamiya A, Kobayashi T, Yamazaki D, Oda A, Takenawa T, Nakauchi H.

Blood. 2007 Nov 15;110(10):3637-47. Epub 2007 Jul 30.

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