Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 32

1.

SCO-267, a GPR40 Full Agonist, Improves Glycemic and Body Weight Control in Rat Models of Diabetes and Obesity.

Ueno H, Ito R, Abe SI, Ookawara M, Miyashita H, Ogino H, Miyamoto Y, Yoshihara T, Kobayashi A, Tsujihata Y, Takeuchi K, Watanabe M, Yamada Y, Maekawa T, Nishigaki N, Moritoh Y.

J Pharmacol Exp Ther. 2019 Aug;370(2):172-181. doi: 10.1124/jpet.118.255885. Epub 2019 Jun 10.

PMID:
31182471
2.

Endoscopic Ultrasonography-guided Fine-needle Aspiration Revealed Metastasis-induced Acute Pancreatitis in a Patient with Adrenocortical Carcinoma: A Case Report.

Mori T, Kondo H, Naitoh I, Koyama T, Takenaka Y, Komai H, Araki S, Kitagawa M, Nishigaki N, Tanaka Y, Itoh K, Hasegawa C, Kawai T, Hayashi K.

Intern Med. 2019 Jun 7. doi: 10.2169/internalmedicine.2450-18. [Epub ahead of print]

3.

Antihypertensive treatment for hypertensive patients with heart failure using real-world Japanese data: subanalysis of the Retrospective study of antihypertensives for lowering blood pressure (REAL) study.

Ohishi M, Yoshida T, Nishigaki N, Oh A, Shimasaki Y.

Clin Exp Hypertens. 2019 Mar 26:1-7. doi: 10.1080/10641963.2019.1590384. [Epub ahead of print]

PMID:
30912679
4.

Treatment patterns and adherence to antihypertensive combination therapies in Japan using a claims database.

Ishida T, Oh A, Hiroi S, Shimasaki Y, Nishigaki N, Tsuchihashi T.

Hypertens Res. 2019 Feb;42(2):249-256. doi: 10.1038/s41440-018-0127-0. Epub 2018 Nov 16.

PMID:
30443023
5.

Effects of mismatches distant from the target position on gene correction with a 5'-tailed duplex.

Suzuki T, Yanai Y, Nishigaki N, Nakatsu Y, Tsuzuki T, Kamiya H.

J Biosci Bioeng. 2018 May;125(5):619-623. doi: 10.1016/j.jbiosc.2017.12.017. Epub 2018 Feb 1.

PMID:
29361419
6.

Humoral Hypercalcemia of Malignancy with a Parathyroid Hormone-Related Peptide-Secreting Intrahepatic Cholangiocarcinoma Accompanied by a Gastric Cancer.

Takeda K, Kimura R, Nishigaki N, Sato S, Okamoto A, Watanabe K, Yasui S.

Case Rep Endocrinol. 2017;2017:7012520. doi: 10.1155/2017/7012520. Epub 2017 May 10.

7.

Persistent reflux symptoms cause anxiety, depression, and mental health and sleep disorders in gastroesophageal reflux disease patients.

Kimura Y, Kamiya T, Senoo K, Tsuchida K, Hirano A, Kojima H, Yamashita H, Yamakawa Y, Nishigaki N, Ozeki T, Endo M, Nakanishi K, Sando M, Inagaki Y, Shikano M, Mizoshita T, Kubota E, Tanida S, Kataoka H, Katsumi K, Joh T.

J Clin Biochem Nutr. 2016 Jul;59(1):71-7. doi: 10.3164/jcbn.16-9. Epub 2016 May 21.

8.

Cleavage of Target DNA Promotes Sequence Conversion with a Tailed Duplex.

Suzuki T, Imada T, Nishigaki N, Kobayashi M, Matsuoka I, Kamiya H.

Biol Pharm Bull. 2016;39(8):1392-5. doi: 10.1248/bpb.b16-00325.

9.

Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism.

Grimshaw CE, Jennings A, Kamran R, Ueno H, Nishigaki N, Kosaka T, Tani A, Sano H, Kinugawa Y, Koumura E, Shi L, Takeuchi K.

PLoS One. 2016 Jun 21;11(6):e0157509. doi: 10.1371/journal.pone.0157509. eCollection 2016.

10.

Insertion and Deletion Mismatches Distant from the Target Position Improve Gene Correction with a Tailed Duplex.

Kamiya H, Nishigaki N, Ikeda A, Yukawa S, Morita Y, Nakatsu Y, Tsuzuki T, Harashima H.

Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):379-88. doi: 10.1080/15257770.2016.1163384. Epub 2016 Jun 2.

11.

Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists.

Hasui T, Ohyabu N, Ohra T, Fuji K, Sugimoto T, Fujimoto J, Asano K, Oosawa M, Shiotani S, Nishigaki N, Kusumoto K, Matsui H, Mizukami A, Habuka N, Sogabe S, Endo S, Ono M, Siedem CS, Tang TP, Gauthier C, De Meese LA, Boyd SA, Fukumoto S.

Bioorg Med Chem. 2014 Oct 1;22(19):5428-45. doi: 10.1016/j.bmc.2014.07.038. Epub 2014 Aug 12.

PMID:
25187277
12.

Identification of benzoxazin-3-one derivatives as novel, potent, and selective nonsteroidal mineralocorticoid receptor antagonists.

Hasui T, Matsunaga N, Ora T, Ohyabu N, Nishigaki N, Imura Y, Igata Y, Matsui H, Motoyaji T, Tanaka T, Habuka N, Sogabe S, Ono M, Siedem CS, Tang TP, Gauthier C, De Meese LA, Boyd SA, Fukumoto S.

J Med Chem. 2011 Dec 22;54(24):8616-31. doi: 10.1021/jm2011645. Epub 2011 Nov 29.

PMID:
22074142
13.

Antihypertensive, insulin-sensitising and renoprotective effects of a novel, potent and long-acting angiotensin II type 1 receptor blocker, azilsartan medoxomil, in rat and dog models.

Kusumoto K, Igata H, Ojima M, Tsuboi A, Imanishi M, Yamaguchi F, Sakamoto H, Kuroita T, Kawaguchi N, Nishigaki N, Nagaya H.

Eur J Pharmacol. 2011 Nov 1;669(1-3):84-93. doi: 10.1016/j.ejphar.2011.07.014. Epub 2011 Jul 28.

PMID:
21816148
14.

Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts.

Burger D, Montezano AC, Nishigaki N, He Y, Carter A, Touyz RM.

Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1898-907. doi: 10.1161/ATVBAHA.110.222703. Epub 2011 May 19.

PMID:
21597004
15.

Angiotensin II and the vascular phenotype in hypertension.

Savoia C, Burger D, Nishigaki N, Montezano A, Touyz RM.

Expert Rev Mol Med. 2011 Mar 30;13:e11. doi: 10.1017/S1462399411001815. Review.

PMID:
21450123
16.

New insights into molecular mechanisms of hypertension.

Burger D, Nishigaki N, Touyz RM.

Curr Opin Nephrol Hypertens. 2010 Mar;19(2):160-2. doi: 10.1097/MNH.0b013e32833680c4. No abstract available.

PMID:
20098323
17.

Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors.

Hasegawa M, Nishigaki N, Washio Y, Kano K, Harris PA, Sato H, Mori I, West RI, Shibahara M, Toyoda H, Wang L, Nolte RT, Veal JM, Cheung M.

J Med Chem. 2007 Sep 6;50(18):4453-70. Epub 2007 Aug 4.

PMID:
17676829
18.

A hexapentaene-extended quinocumulene cyclotrimerized to a tricyclobutabenzene derivative.

Kawase T, Minami Y, Nishigaki N, Okano S, Kurata H, Oda M.

Angew Chem Int Ed Engl. 2004 Dec 27;44(2):316-9. No abstract available.

PMID:
15614887
19.

Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes.

Matsuura K, Nagai T, Nishigaki N, Oyama T, Nishi J, Wada H, Sano M, Toko H, Akazawa H, Sato T, Nakaya H, Kasanuki H, Komuro I.

J Biol Chem. 2004 Mar 19;279(12):11384-91. Epub 2003 Dec 31. Erratum in: J Biol Chem. 2013 Dec 27;288(52):37366.

20.

Anilinopyrazole as selective CDK2 inhibitors: design, synthesis, biological evaluation, and X-ray crystallographic analysis.

Tang J, Shewchuk LM, Sato H, Hasegawa M, Washio Y, Nishigaki N.

Bioorg Med Chem Lett. 2003 Sep 15;13(18):2985-8.

PMID:
12941317
21.

The effect of high sugar intake on the development of periradicular lesions in rats with type 2 diabetes.

Iwama A, Nishigaki N, Nakamura K, Imaizumi I, Shibata N, Yamasaki M, Nakamura H, Kameyama Y, Kapila Y.

J Dent Res. 2003 Apr;82(4):322-5.

PMID:
12651940
22.
23.

Effect of methotrexate-induced neutropenia on pulpal inflammation in rats.

Nakamura K, Yamasaki M, Nishigaki N, Iwama A, Imaizumi I, Nakamura H, Kameyama Y.

J Endod. 2002 Apr;28(4):287-90.

PMID:
12043865
24.

Cytoskeletal regulation of the signal transduction of prostaglandin EP4 receptor.

Nishigaki N, Chang C, Ichikawa A, Negishi M.

Biochim Biophys Acta. 1998 Mar 6;1391(1):110-6.

PMID:
9518573
28.

The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and northern blot analysis.

Katsuyama M, Nishigaki N, Sugimoto Y, Morimoto K, Negishi M, Narumiya S, Ichikawa A.

FEBS Lett. 1995 Sep 25;372(2-3):151-6.

29.

Identification of prostaglandin E receptor 'EP2' cloned from mastocytoma cells EP4 subtype.

Nishigaki N, Negishi M, Honda A, Sugimoto Y, Namba T, Narumiya S, Ichikawa A.

FEBS Lett. 1995 May 15;364(3):339-41.

30.

Characterization of the prostaglandin E receptor expressed on a cultured mast cell line, BNu-2cl3.

Nishigaki N, Negishi M, Sugimoto Y, Namba T, Narumiya S, Ichikawa A.

Biochem Pharmacol. 1993 Sep 1;46(5):863-9.

PMID:
7690567

Supplemental Content

Loading ...
Support Center