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Items: 20


Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway.

Chen YH, Kratchmarov R, Lin WW, Rothman NJ, Yen B, Adams WC, Nish SA, Rathmell JC, Reiner SL.

Cell Rep. 2018 Jan 23;22(4):860-868. doi: 10.1016/j.celrep.2017.12.087. Epub 2018 Jan 28.


Correction: IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination.

Kratchmarov R, Nish SA, Lin WW, Adams WC, Chen YH, Yen B, Rothman NJ, Klein U, Reiner SL.

Immunohorizons. 2018 Jan 2;2(1):12-13. doi: 10.4049/immunohorizons.1700072. No abstract available.


IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination.

Kratchmarov R, Nish SA, Lin WW, Adams WC, Chen YH, Yen B, Rothman NJ, Klein U, Reiner SL.

Immunohorizons. 2017 Sep 1;1(7):156-161. doi: 10.4049/immunohorizons.1700012. Erratum in: Immunohorizons. 2018 Jan 2;2(1):12-13.


Lymphocyte Fate and Metabolism: A Clonal Balancing Act.

Nish SA, Lin WW, Reiner SL.

Trends Cell Biol. 2017 Dec;27(12):946-954. doi: 10.1016/j.tcb.2017.07.005. Epub 2017 Aug 14. Review.


Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal.

Adams WC, Chen YH, Kratchmarov R, Yen B, Nish SA, Lin WW, Rothman NJ, Luchsinger LL, Klein U, Busslinger M, Rathmell JC, Snoeck HW, Reiner SL.

Cell Rep. 2016 Dec 20;17(12):3142-3152. doi: 10.1016/j.celrep.2016.11.065.


CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions.

Nish SA, Zens KD, Kratchmarov R, Lin WW, Adams WC, Chen YH, Yen B, Rothman NJ, Bhandoola A, Xue HH, Farber DL, Reiner SL.

J Exp Med. 2017 Jan;214(1):39-47. doi: 10.1084/jem.20161046. Epub 2016 Dec 6.


CD8+ T Lymphocyte Self-Renewal during Effector Cell Determination.

Lin WW, Nish SA, Yen B, Chen YH, Adams WC, Kratchmarov R, Rothman NJ, Bhandoola A, Xue HH, Reiner SL.

Cell Rep. 2016 Nov 8;17(7):1773-1782. doi: 10.1016/j.celrep.2016.10.032.


Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses.

Lau CM, Nish SA, Yogev N, Waisman A, Reiner SL, Reizis B.

J Exp Med. 2016 Mar 7;213(3):415-31. doi: 10.1084/jem.20150642. Epub 2016 Feb 22.


Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation.

Lin WH, Adams WC, Nish SA, Chen YH, Yen B, Rothman NJ, Kratchmarov R, Okada T, Klein U, Reiner SL.

Cell Rep. 2015 Dec 15;13(10):2203-18. doi: 10.1016/j.celrep.2015.10.072. Epub 2015 Nov 25.


Cutting edge: CXCR4 is critical for CD8+ memory T cell homeostatic self-renewal but not rechallenge self-renewal.

Chaix J, Nish SA, Lin WH, Rothman NJ, Ding L, Wherry EJ, Reiner SL.

J Immunol. 2014 Aug 1;193(3):1013-6. doi: 10.4049/jimmunol.1400488. Epub 2014 Jun 27.


T cell-intrinsic role of IL-6 signaling in primary and memory responses.

Nish SA, Schenten D, Wunderlich FT, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J, Medzhitov R.

Elife. 2014 May 19;3:e01949. doi: 10.7554/eLife.01949.


Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells.

Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H, Medzhitov R.

Immunity. 2014 Jan 16;40(1):78-90. doi: 10.1016/j.immuni.2013.10.023. Erratum in: Immunity. 2014 May 15;40(5):814.


Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells.

Gao Y, Nish SA, Jiang R, Hou L, Licona-Limón P, Weinstein JS, Zhao H, Medzhitov R.

Immunity. 2013 Oct 17;39(4):722-32. doi: 10.1016/j.immuni.2013.08.028. Epub 2013 Sep 26.


MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice.

Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R.

Nat Commun. 2012;3:1120. doi: 10.1038/ncomms2113.


Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response.

Sokol CL, Chu NQ, Yu S, Nish SA, Laufer TM, Medzhitov R.

Nat Immunol. 2009 Jul;10(7):713-20. doi: 10.1038/ni.1738. Epub 2009 May 24.


Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity.

Hondowicz BD, Fields ML, Nish SA, Larkin J, Caton AJ, Erikson J.

J Autoimmun. 2008 Sep;31(2):98-109. doi: 10.1016/j.jaut.2008.04.022. Epub 2008 Jun 9.


CD4+ CD25+ regulatory T cells inhibit the maturation but not the initiation of an autoantibody response.

Fields ML, Hondowicz BD, Metzgar MH, Nish SA, Wharton GN, Picca CC, Caton AJ, Erikson J.

J Immunol. 2005 Oct 1;175(7):4255-64.


The influence of effector T cells and Fas ligand on lupus-associated B cells.

Fields ML, Nish SA, Hondowicz BD, Metzgar MH, Wharton GN, Caton AJ, Erikson J.

J Immunol. 2005 Jul 1;175(1):104-11.


The regulation and activation potential of autoreactive B cells.

Fields ML, Seo SJ, Nish SA, Tsai JH, Caton AJ, Erikson J.

Immunol Res. 2003;27(2-3):219-34. Review.


The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells.

Seo SJ, Fields ML, Buckler JL, Reed AJ, Mandik-Nayak L, Nish SA, Noelle RJ, Turka LA, Finkelman FD, Caton AJ, Erikson J.

Immunity. 2002 Apr;16(4):535-46.

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