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Items: 1 to 50 of 456

1.

Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy".

Masters EA, Trombetta RP, de Mesy Bentley KL, Boyce BF, Gill AL, Gill SR, Nishitani K, Ishikawa M, Morita Y, Ito H, Bello-Irizarry SN, Ninomiya M, Brodell JD Jr, Lee CC, Hao SP, Oh I, Xie C, Awad HA, Daiss JL, Owen JR, Kates SL, Schwarz EM, Muthukrishnan G.

Bone Res. 2019 Jul 15;7:20. doi: 10.1038/s41413-019-0061-z. eCollection 2019. Review.

2.

Management of tooth extraction in a patient with ELANE gene mutation-induced cyclic neutropenia: A case report.

Aota K, Kani K, Yamanoi T, Momota Y, Ninomiya M, Yumoto H, Azuma M.

Medicine (Baltimore). 2019 Sep;98(39):e17372. doi: 10.1097/MD.0000000000017372.

3.

The Pathogenic Factors from Oral Streptococci for Systemic Diseases.

Yumoto H, Hirota K, Hirao K, Ninomiya M, Murakami K, Fujii H, Miyake Y.

Int J Mol Sci. 2019 Sep 15;20(18). pii: E4571. doi: 10.3390/ijms20184571. Review.

4.

The reduction of miR146b-5p in monocytes and T cells could contribute to the immunopathogenesis of hepatitis C virus infection.

Kondo Y, Kogure T, Ninomiya M, Fukuda R, Monma N, Ikeo K, Tanaka Y.

Sci Rep. 2019 Sep 16;9(1):13393. doi: 10.1038/s41598-019-49706-9.

5.

Comparative analysis of stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors with neuroprotective and anti-inflammatory activities.

Nagumo M, Ninomiya M, Oshima N, Itoh T, Tanaka K, Nishina A, Koketsu M.

Bioorg Med Chem Lett. 2019 Sep 1;29(17):2475-2479. doi: 10.1016/j.bmcl.2019.07.026. Epub 2019 Jul 18.

PMID:
31350127
6.

Comparison of hepatitis B virus genotypes B and C among chronically hepatitis B virus-infected patients who received nucleos(t)ide analogs: A multicenter retrospective study.

Inoue J, Akahane T, Nakayama H, Kimura O, Kobayashi T, Kisara N, Sato T, Morosawa T, Izuma M, Kakazu E, Ninomiya M, Iwata T, Takai S, Nakamura T, Sano A, Niitsuma H, Masamune A; THERME Study Group.

Hepatol Res. 2019 Jun 29. doi: 10.1111/hepr.13398. [Epub ahead of print]

PMID:
31254482
7.

Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.

Suematsu N, Ninomiya M, Sugiyama H, Udagawa T, Tanaka K, Koketsu M.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2243-2247. doi: 10.1016/j.bmcl.2019.06.038. Epub 2019 Jun 20.

PMID:
31253531
8.

Urinary adiponectin as a new diagnostic index for chronic kidney disease due to diabetic nephropathy.

Yamakado S, Cho H, Inada M, Morikawa M, Jiang YH, Saito K, Nakaishi K, Watabe S, Takagi H, Kaneda M, Nakatsuma A, Ninomiya M, Imachi H, Arai T, Yoshimoto T, Murao K, Chang JH, Chen SM, Shih YC, Zeng MJ, Ke LY, Chen CH, Yoshimura T, Miura T, Ito E.

BMJ Open Diabetes Res Care. 2019 May 30;7(1):e000661. doi: 10.1136/bmjdrc-2019-000661. eCollection 2019.

9.

Relationship of oral conditions to the incidence of infective endocarditis in periodontitis patients with valvular heart disease: a cross-sectional study.

Ninomiya M, Hashimoto M, Yamanouchi K, Fukumura Y, Nagata T, Naruishi K.

Clin Oral Investig. 2019 Jun 13. doi: 10.1007/s00784-019-02973-2. [Epub ahead of print]

PMID:
31197658
10.

Small Interfering RNA Screening for the Small GTPase Rab Proteins Identifies Rab5B as a Major Regulator of Hepatitis B Virus Production.

Inoue J, Ninomiya M, Umetsu T, Nakamura T, Kogure T, Kakazu E, Iwata T, Takai S, Sano A, Fukuda M, Watashi K, Isogawa M, Tanaka Y, Shimosegawa T, McNiven MA, Masamune A.

J Virol. 2019 Jul 17;93(15). pii: e00621-19. doi: 10.1128/JVI.00621-19. Print 2019 Aug 1.

PMID:
31118260
11.

Acute-onset Autoimmune Hepatitis in a Patient with Selective Immunoglobulin M Deficiency.

Sano A, Inoue J, Kakazu E, Ninomiya M, Iwata T, Morosawa T, Takai S, Nakamura T, Masamune A.

Intern Med. 2019 Aug 1;58(15):2185-2190. doi: 10.2169/internalmedicine.2607-18. Epub 2019 Apr 17.

12.

Branched chain amino acids are associated with the heterogeneity of the area of lipid droplets in hepatocytes of patients with non-alcoholic fatty liver disease.

Kakazu E, Sano A, Morosawa T, Inoue J, Ninomiya M, Iwata T, Nakamura T, Takai S, Sawada S, Katagiri H, Shimosegawa T, Masamune A.

Hepatol Res. 2019 Aug;49(8):860-871. doi: 10.1111/hepr.13346. Epub 2019 May 21.

PMID:
30972908
13.

Calcium Phosphate Spacers for the Local Delivery of Sitafloxacin and Rifampin to Treat Orthopedic Infections: Efficacy and Proof of Concept in a Mouse Model of Single-Stage Revision of Device-Associated Osteomyelitis.

Trombetta RP, Ninomiya MJ, El-Atawneh IM, Knapp EK, de Mesy Bentley KL, Dunman PM, Schwarz EM, Kates SL, Awad HA.

Pharmaceutics. 2019 Feb 22;11(2). pii: E94. doi: 10.3390/pharmaceutics11020094.

14.

Bezafibrate Improves GLOBE and UK-PBC Scores and Long-Term Outcomes in Patients With Primary Biliary Cholangitis.

Honda A, Tanaka A, Kaneko T, Komori A, Abe M, Inao M, Namisaki T, Hashimoto N, Kawata K, Takahashi A, Ninomiya M, Kang JH, Arakawa M, Yamagiwa S, Joshita S, Umemura T, Sato K, Kaneko A, Kikuchi K, Itakura J, Nomura T, Kakisaka K, Fujii H, Kawada N, Takikawa Y, Masaki T, Ohira H, Mochida S, Yoshiji H, Iimuro S, Matsuzaki Y, Takikawa H; Japan PBC Study Group.

Hepatology. 2019 Feb 8. doi: 10.1002/hep.30552. [Epub ahead of print]

PMID:
30737815
15.

Total Synthesis of Actinorhodin.

Ninomiya M, Ando Y, Kudo F, Ohmori K, Suzuki K.

Angew Chem Int Ed Engl. 2019 Mar 22;58(13):4264-4270. doi: 10.1002/anie.201814172. Epub 2019 Feb 27.

PMID:
30690838
16.

Sentulic acid isolated from Sandoricum koetjape Merr attenuates lipopolysaccharide and interferon gamma co-stimulated nitric oxide production in murine macrophage RAW264 cells.

Itoh T, Katsurayama K, Efdi M, Ninomiya M, Koketsu M.

Bioorg Med Chem Lett. 2018 Dec 1;28(22):3496-3501. doi: 10.1016/j.bmcl.2018.10.008. Epub 2018 Oct 9.

PMID:
30318438
17.

Tracking Anti-Staphylococcus aureus Antibodies Produced In Vivo and Ex Vivo during Foot Salvage Therapy for Diabetic Foot Infections Reveals Prognostic Insights and Evidence of Diversified Humoral Immunity.

Oh I, Muthukrishnan G, Ninomiya MJ, Brodell JD Jr, Smith BL, Lee CC, Gill SR, Beck CA, Schwarz EM, Daiss JL.

Infect Immun. 2018 Nov 20;86(12). pii: e00629-18. doi: 10.1128/IAI.00629-18. Print 2018 Dec.

18.

[Staged Hybrid Treatment for a Coronary Artery Pseudoaneurysm after Percutaneous Coronary Intervention;Report of a Case].

Arima D, Hisagi M, Nonaka T, Ninomiya M, Ohtsuka T.

Kyobu Geka. 2018 Sep;71(9):693-695. Japanese.

PMID:
30185745
19.

En Bloc Left Pulmonary Vein and Appendage Isolation in Thoracoscopic Surgery for Atrial Fibrillation.

Ohtsuka T, Nonaka T, Hisagi M, Ninomiya M.

Ann Thorac Surg. 2018 Nov;106(5):1340-1347. doi: 10.1016/j.athoracsur.2018.06.065. Epub 2018 Aug 14.

PMID:
30118710
20.

A Mass Filling the Right Atrium: Primary Cardiac Rhabdomyosarcoma.

Kimura A, Tsuji M, Isogai T, Nagata K, Kato K, Hisagi M, Nonaka T, Ninomiya M, Kiriu T, Tanaka H, Tejima T.

Intern Med. 2018 Dec 15;57(24):3575-3580. doi: 10.2169/internalmedicine.0657-17. Epub 2018 Aug 10.

21.

Short-term outcomes of multicenter prospective cohort study of gastric endoscopic resection: 'Real-world evidence' in Japan.

Suzuki H, Takizawa K, Hirasawa T, Takeuchi Y, Ishido K, Hoteya S, Yano T, Tanaka S, Endo M, Nakagawa M, Toyonaga T, Doyama H, Hirasawa K, Matsuda M, Yamamoto H, Fujishiro M, Hashimoto S, Maeda Y, Oyama T, Takenaka R, Yamamoto Y, Naito Y, Michida T, Kobayashi N, Kawahara Y, Hirano M, Jin M, Hori S, Niwa Y, Hikichi T, Shimazu T, Ono H, Tanabe S, Kondo H, Iishi H, Ninomiya M; Ichiro Oda for J-WEB/EGC group.

Dig Endosc. 2019 Jan;31(1):30-39. doi: 10.1111/den.13246. Epub 2018 Sep 25.

PMID:
30058258
22.

Prognostic Significance of Preoperative Controlling Nutritional Status (CONUT) Score in Patients Undergoing Hepatic Resection for Hepatocellular Carcinoma: A Multi-institutional Study.

Harimoto N, Yoshizumi T, Inokuchi S, Itoh S, Adachi E, Ikeda Y, Uchiyama H, Utsunomiya T, Kajiyama K, Kimura K, Kishihara F, Sugimachi K, Tsujita E, Ninomiya M, Fukuzawa K, Maeda T, Shirabe K, Maehara Y.

Ann Surg Oncol. 2018 Oct;25(11):3316-3323. doi: 10.1245/s10434-018-6672-6. Epub 2018 Jul 26.

PMID:
30051372
23.

Synthesis and antimicrobial activity of β-carboline derivatives with N2-alkyl modifications.

Suzuki K, Nomura I, Ninomiya M, Tanaka K, Koketsu M.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2976-2978. doi: 10.1016/j.bmcl.2018.06.050. Epub 2018 Jul 6.

PMID:
30001916
24.

Staphylococcus aureus Evasion of Host Immunity in the Setting of Prosthetic Joint Infection: Biofilm and Beyond.

Ricciardi BF, Muthukrishnan G, Masters E, Ninomiya M, Lee CC, Schwarz EM.

Curr Rev Musculoskelet Med. 2018 Sep;11(3):389-400. doi: 10.1007/s12178-018-9501-4. Review.

25.

Development of apheresis techniques and equipment designed for patients weighing less than 10 kg.

Pratx LB, Gru I, Spotti M, Sánchez DD, Ninomiya M, Marcarián G, Ahmed N.

Transfus Apher Sci. 2018 Jun;57(3):331-336. doi: 10.1016/j.transci.2018.05.014. Epub 2018 May 10. Review.

PMID:
29945827
26.

Synthesis of coumarin derivatives and their cytoprotective effects on t-BHP-induced oxidative damage in HepG2 cells.

Ando T, Nagumo M, Ninomiya M, Tanaka K, Linhardt RJ, Koketsu M.

Bioorg Med Chem Lett. 2018 Aug 1;28(14):2422-2425. doi: 10.1016/j.bmcl.2018.06.018. Epub 2018 Jun 12.

PMID:
29914769
27.

Inhibitory effect of silibinin on hepatitis B virus entry.

Umetsu T, Inoue J, Kogure T, Kakazu E, Ninomiya M, Iwata T, Takai S, Nakamura T, Sano A, Shimosegawa T.

Biochem Biophys Rep. 2018 Mar 31;14:20-25. doi: 10.1016/j.bbrep.2018.03.003. eCollection 2018 Jul.

28.

Thoracoscopic stapler-and-loop technique for left atrial appendage closure in nonvalvular atrial fibrillation: Mid-term outcomes in 201 patients.

Ohtsuka T, Nonaka T, Hisagi M, Ninomiya M, Masukawa A, Ota T.

Heart Rhythm. 2018 Sep;15(9):1314-1320. doi: 10.1016/j.hrthm.2018.05.026. Epub 2018 May 24.

PMID:
29803851
29.

Phytol isolated from watermelon (Citrullus lanatus) sprouts induces cell death in human T-lymphoid cell line Jurkat cells via S-phase cell cycle arrest.

Itoh T, Ono A, Kawaguchi K, Teraoka S, Harada M, Sumi K, Ando M, Tsukamasa Y, Ninomiya M, Koketsu M, Hashizume T.

Food Chem Toxicol. 2018 May;115:425-435. doi: 10.1016/j.fct.2018.03.033. Epub 2018 Mar 30.

PMID:
29608981
30.

An in silico-designed flavone derivative, 6-fluoro-4'-hydroxy-3',5'-dimetoxyflavone, has a greater anti-human cytomegalovirus effect than ganciclovir in infected cells.

Fujimoto KJ, Nema D, Ninomiya M, Koketsu M, Sadanari H, Takemoto M, Daikoku T, Murayama T.

Antiviral Res. 2018 Jun;154:10-16. doi: 10.1016/j.antiviral.2018.03.006. Epub 2018 Mar 17.

PMID:
29559264
31.

Ventricular Septal Perforation: A Rare but Life-Threatening Complication Associated with Takotsubo Syndrome.

Tsuji M, Isogai T, Okabe Y, Nishimura Y, Itagaki S, Enatsu K, Hisagi M, Nonaka T, Ninomiya M, Otsuka T, Tanaka H, Tejima T.

Intern Med. 2018 Jun 1;57(11):1605-1609. doi: 10.2169/internalmedicine.0014-17. Epub 2018 Feb 9.

32.

Chemical Constituents of Coreopsis lanceolata Stems and Their Antitermitic Activity Against the Subterranean Termite Coptotermes curvignathus.

Pardede A, Adfa M, Kusnanda AJ, Ninomiya M, Koketsu M.

J Econ Entomol. 2018 Apr 2;111(2):803-807. doi: 10.1093/jee/tox376.

PMID:
29385516
33.

The profiling of plasma free amino acids and the relationship between serum albumin and plasma-branched chain amino acids in chronic liver disease: a single-center retrospective study.

Sano A, Kakazu E, Morosawa T, Inoue J, Kogure T, Ninomiya M, Iwata T, Umetsu T, Nakamura T, Takai S, Shimosegawa T.

J Gastroenterol. 2018 Aug;53(8):978-988. doi: 10.1007/s00535-018-1435-5. Epub 2018 Jan 27.

PMID:
29380062
34.

Cellular Membrane Trafficking Machineries Used by the Hepatitis Viruses.

Inoue J, Ninomiya M, Shimosegawa T, McNiven MA.

Hepatology. 2018 Aug;68(2):751-762. doi: 10.1002/hep.29785. Review.

PMID:
29331069
35.

Acute-onset Autoimmune Hepatitis in a Young Woman with Type 1 Diabetes Mellitus.

Takai S, Inoue J, Kogure T, Kakazu E, Ninomiya M, Iwata T, Umetsu T, Nakamura T, Sano A, Shimosegawa T.

Intern Med. 2018 Jun 1;57(11):1591-1596. doi: 10.2169/internalmedicine.9728-17. Epub 2018 Jan 11.

36.

Iloneoside: a cytotoxic ditigloylated pregnane glycoside from the leaves of Gongronema latifolium Benth.

Gyebi GA, Adebayo JO, Olorundare OE, Pardede A, Ninomiya M, Saheed AO, Babatunde AS, Koketsu M.

Nat Prod Res. 2018 Dec;32(24):2882-2886. doi: 10.1080/14786419.2017.1385019. Epub 2017 Oct 16.

PMID:
29034743
37.

Comparative Antileukemic Activity of a Tetranorditerpene Isolated from Polyalthia longifolia Leaves and the Derivative against Human Leukemia HL-60 Cells.

Afolabi S, Olorundare O, Ninomiya M, Babatunde A, Mukhtar H, Koketsu M.

J Oleo Sci. 2017 Oct 1;66(10):1169-1174. doi: 10.5650/jos.ess17042. Epub 2017 Sep 15.

38.

Gastroesophageal Variceal Bleeding Successfully Controlled by Partial Splenic Embolization.

Kogure T, Inoue J, Kakazu E, Ninomiya M, Shimosegawa T.

Intern Med. 2017;56(11):1339-1343. doi: 10.2169/internalmedicine.56.8167. Epub 2017 Jun 1.

39.

5,7-Dihydroxyflavone Analogues May Regulate Lipopolysaccharide-Induced Inflammatory Responses by Suppressing IκBα-Linked Akt and ERK5 Phosphorylation in RAW 264.7 Macrophages.

Nishina A, Shimizu K, Koketsu M, Ninomiya M, Sato D, Suzuki T, Hayakawa S, Kimura H.

Evid Based Complement Alternat Med. 2017;2017:7898973. doi: 10.1155/2017/7898973. Epub 2017 Apr 30.

40.

Effects of Flavonoids and Triterpene Analogues from Leaves of Eleutherococcus sieboldianus (Makino) Koidz. 'Himeukogi' in 3T3-L1 Preadipocytes.

Nishina A, Itagaki M, Suzuki Y, Koketsu M, Ninomiya M, Sato D, Suzuki T, Hayakawa S, Kuroda M, Kimura H.

Molecules. 2017 Apr 22;22(4). pii: E671. doi: 10.3390/molecules22040671.

41.

[A Case of Malignant Obstruction of the Colon Due to Peritoneal Dissemination of Gastric Carcinoma Treated with Colon Stenting and Colectomy after Chemotherapy].

Kanazawa T, Ninomiya M, Choda Y, Ishida M, Miyake S, Satoh D, Tokumoto N, Harano M, Matsukawa H, Ojima Y, Idani H, Shiozaki S, Okajima M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):2389-2391. Japanese.

PMID:
28133331
42.

[A Case of Advanced Gastric Cancer with Para-Aortic Lymph Node Dissection after Neoadjuvant Chemotherapy].

Ogawa T, Choda Y, Ninomiya M, Nagai Y, Mimura N, Miyake S, Ishida M, Matsukawa H, Ojima Y, Idani H, Shiozaki S, Okajima M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):2205-2207. Japanese.

PMID:
28133270
43.

[A Long-Surviving Case of Unresectable Gall Bladder Carcinoma Treated with Gemcitabine-Based Chemotherapy].

Matsukawa H, Shiozaki S, Satoh D, Araki H, Mimura N, Ogawa T, Idani H, Ojima Y, Harano M, Kanazawa T, Choda Y, Sumitani D, Ishida M, Okajima M, Ninomiya M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):2089-2091. Japanese.

PMID:
28133231
44.

[Assessment of Endoscopic Resection and Partial Duodenectomy for Duodenal Mucosal Tumor].

Mimura N, Matsukawa H, Shiozaki S, Satoh D, Araki H, Ogawa T, Idani H, Ojima Y, Harano M, Kanazawa T, Choda Y, Sumitani D, Ishida M, Miyake S, Okajima M, Ninomiya M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):1430-1431. Japanese.

PMID:
28133013
45.

Long-term outcomes of laparoscopy-assisted distal gastrectomy with suprapancreatic nodal dissection for clinical stage I gastric cancer: a multicenter phase II trial (JCOG0703).

Hiki N, Katai H, Mizusawa J, Nakamura K, Nakamori M, Yoshikawa T, Kojima K, Imamoto H, Ninomiya M, Kitano S, Terashima M; Stomach Cancer Study Group of Japan Clinical Oncology Group.

Gastric Cancer. 2018 Jan;21(1):155-161. doi: 10.1007/s10120-016-0687-0. Epub 2017 Jan 16.

PMID:
28093654
46.

Identification of Genotype 2 HCV in Serotype-1 Hepatitis C Patients Unresponsive to Daclatasvir plus Asunaprevir Treatment.

Inoue J, Kanno A, Wakui Y, Miura M, Kobayashi T, Morosawa T, Kogure T, Kakazu E, Ninomiya M, Fujisaka Y, Umetsu T, Takai S, Nakamura T, Shimosegawa T.

Tohoku J Exp Med. 2017 Jan;241(1):21-28. doi: 10.1620/tjem.241.21.

47.

Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis.

de Mesy Bentley KL, Trombetta R, Nishitani K, Bello-Irizarry SN, Ninomiya M, Zhang L, Chung HL, McGrath JL, Daiss JL, Awad HA, Kates SL, Schwarz EM.

J Bone Miner Res. 2017 May;32(5):985-990. doi: 10.1002/jbmr.3055. Epub 2017 Jan 26.

48.

CoCl2 Decreases EC-SOD Expression through Histone Deacetylation in COS7 Cells.

Hattori S, Kamiya T, Hara H, Ninomiya M, Koketsu M, Adachi T.

Biol Pharm Bull. 2016;39(12):2036-2041.

49.

MiR-139-5p is associated with inflammatory regulation through c-FOS suppression, and contributes to the progression of primary biliary cholangitis.

Katsumi T, Ninomiya M, Nishina T, Mizuno K, Tomita K, Haga H, Okumoto K, Saito T, Shimosegawa T, Ueno Y.

Lab Invest. 2016 Nov;96(11):1165-1177. doi: 10.1038/labinvest.2016.95. Epub 2016 Sep 26.

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