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Items: 24

1.

Rapid and accurate structure-based therapeutic peptide design using GPU accelerated thermodynamic integration.

Garton M, Corbi-Verge C, Hu Y, Nim S, Tarasova N, Sherborne B, Kim PM.

Proteins. 2019 Mar;87(3):236-244. doi: 10.1002/prot.25644. Epub 2019 Jan 4.

PMID:
30520126
2.

Make azoles active again: chalcones as potent reversal agents of transporters-mediated resistance in Candida albicans.

Nim S, Baghel P, Tran-Nguyen VK, Peres B, Nguyen KA, Pietro AD, Falson P, Prasad R, Boumendjel A.

Future Med Chem. 2018 Sep 1;10(18):2177-2186. doi: 10.4155/fmc-2018-0081. Epub 2018 Jul 25.

PMID:
30043631
3.

Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB.

Garton M, Nim S, Stone TA, Wang KE, Deber CM, Kim PM.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1505-1510. doi: 10.1073/pnas.1711837115. Epub 2018 Jan 29.

4.

Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10.

Zhang W, Sartori MA, Makhnevych T, Federowicz KE, Dong X, Liu L, Nim S, Dong A, Yang J, Li Y, Haddad D, Ernst A, Heerding D, Tong Y, Moffat J, Sidhu SS.

J Mol Biol. 2017 Nov 10;429(22):3546-3560. doi: 10.1016/j.jmb.2017.05.025. Epub 2017 Jun 3.

PMID:
28587923
5.

Lathyrol and epoxylathyrol derivatives: Modulation of Cdr1p and Mdr1p drug-efflux transporters of Candida albicans in Saccharomyces cerevisiae model.

Mónico A, Nim S, Duarte N, Rawal MK, Prasad R, Di Pietro A, Ferreira MU.

Bioorg Med Chem. 2017 Jul 1;25(13):3278-3284. doi: 10.1016/j.bmc.2017.04.016. Epub 2017 Apr 16.

PMID:
28479022
6.

Evaluation of Jatrophane Esters from Euphorbia spp. as Modulators of Candida albicans Multidrug Transporters.

Esposito M, Nim S, Nothias LF, Gallard JF, Rawal MK, Costa J, Roussi F, Prasad R, Di Pietro A, Paolini J, Litaudon M.

J Nat Prod. 2017 Feb 24;80(2):479-487. doi: 10.1021/acs.jnatprod.6b00990. Epub 2017 Jan 20.

PMID:
28106996
7.

Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome.

Davey NE, Seo MH, Yadav VK, Jeon J, Nim S, Krystkowiak I, Blikstad C, Dong D, Markova N, Kim PM, Ivarsson Y.

FEBS J. 2017 Feb;284(3):485-498. doi: 10.1111/febs.13995. Epub 2017 Jan 18.

8.
9.

Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads.

Corbi-Verge C, Garton M, Nim S, Kim PM.

Annu Rev Pharmacol Toxicol. 2017 Jan 6;57:39-60. doi: 10.1146/annurev-pharmtox-010716-104805. Epub 2016 Sep 8. Review.

PMID:
27618737
10.

Atomic modelling and systematic mutagenesis identify residues in multiple drug binding sites that are essential for drug resistance in the major Candida transporter Cdr1.

Nim S, Lobato LG, Moreno A, Chaptal V, Rawal MK, Falson P, Prasad R.

Biochim Biophys Acta. 2016 Nov;1858(11):2858-2870. doi: 10.1016/j.bbamem.2016.08.011. Epub 2016 Aug 25.

11.

Protein engineering by highly parallel screening of computationally designed variants.

Sun MG, Seo MH, Nim S, Corbi-Verge C, Kim PM.

Sci Adv. 2016 Jul 20;2(7):e1600692. doi: 10.1126/sciadv.1600692. eCollection 2016 Jul.

12.

Overcoming Multidrug Resistance in Candida albicans: Macrocyclic Diterpenes from Euphorbia Species as Potent Inhibitors of Drug Efflux Pumps.

Nim S, Mónico A, Rawal MK, Duarte N, Prasad R, Di Pietro A, Ferreira MJ.

Planta Med. 2016 Aug;82(13):1180-5. doi: 10.1055/s-0042-106169. Epub 2016 May 4.

PMID:
27145238
13.

Pooled screening for antiproliferative inhibitors of protein-protein interactions.

Nim S, Jeon J, Corbi-Verge C, Seo MH, Ivarsson Y, Moffat J, Tarasova N, Kim PM.

Nat Chem Biol. 2016 Apr;12(4):275-81. doi: 10.1038/nchembio.2026. Epub 2016 Feb 22.

14.

Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis.

Joyal JS, Nim S, Zhu T, Sitaras N, Rivera JC, Shao Z, Sapieha P, Hamel D, Sanchez M, Zaniolo K, St-Louis M, Ouellette J, Montoya-Zavala M, Zabeida A, Picard E, Hardy P, Bhosle V, Varma DR, Gobeil F Jr, Beauséjour C, Boileau C, Klein W, Hollenberg M, Ribeiro-da-Silva A, Andelfinger G, Chemtob S.

Nat Med. 2014 Oct;20(10):1165-73. doi: 10.1038/nm.3669. Epub 2014 Sep 14.

PMID:
25216639
15.

A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening.

Jeon J, Nim S, Teyra J, Datti A, Wrana JL, Sidhu SS, Moffat J, Kim PM.

Genome Med. 2014 Jul 30;6(7):57. doi: 10.1186/s13073-014-0057-7. eCollection 2014.

17.

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes.

Ivarsson Y, Arnold R, McLaughlin M, Nim S, Joshi R, Ray D, Liu B, Teyra J, Pawson T, Moffat J, Li SS, Sidhu SS, Kim PM.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2542-7. doi: 10.1073/pnas.1312296111. Epub 2014 Feb 3.

18.

Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B sub-unit occurs independently of caveolae.

Lajoie P, Kojic LD, Nim S, Li L, Dennis JW, Nabi IR.

J Cell Mol Med. 2009 Sep;13(9B):3218-25. doi: 10.1111/j.1582-4934.2009.00732.x. Epub 2009 Mar 6.

19.

Early effects of spinal cord transection on skeletal muscle properties.

Kelley MD, Nim S, Rousseau G, Fowles JR, Murphy RJ.

Appl Physiol Nutr Metab. 2006 Aug;31(4):398-406.

PMID:
16900229
20.

Proangiogenic effects of protease-activated receptor 2 are tumor necrosis factor-alpha and consecutively Tie2 dependent.

Zhu T, Sennlaub F, Beauchamp MH, Fan L, Joyal JS, Checchin D, Nim S, Lachapelle P, Sirinyan M, Hou X, Bossolasco M, Rivard GE, Heveker N, Chemtob S.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):744-50. Epub 2006 Jan 26.

PMID:
16439712
21.

Apoptosis detected in the amygdala following myocardial infarction in the rat.

Wann BP, Boucher M, Kaloustian S, Nim S, Godbout R, Rousseau G.

Biol Psychiatry. 2006 Mar 1;59(5):430-3. Epub 2005 Oct 3.

PMID:
16202395
22.

Alterations of beta-adrenoceptor responsiveness in postischemic myocardium after 72 h of reperfusion.

Boucher M, Nim S, de Montigny C, Rousseau G.

Eur J Pharmacol. 2004 Jul 14;495(2-3):185-91.

PMID:
15249169
23.

A note on sandflies of Jammu area.

Kumar K, Rahman SJ, Nim S, Chirwatkar KR, Kalra NL.

J Commun Dis. 1983 Dec;15(4):287-9. No abstract available.

PMID:
6674330
24.

Mermithid nematodes in the Anopheles mosquitoes of Bastar district, Madhya Pradesh.

Chirwatkar KR, Nim S, Kulkarni SM.

J Commun Dis. 1983 Jun;15(2):146-8. No abstract available.

PMID:
6630986

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