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Items: 48

1.

Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.

Robichaux JP, Elamin YY, Vijayan RSK, Nilsson MB, Hu L, He J, Zhang F, Pisegna M, Poteete A, Sun H, Li S, Chen T, Han H, Negrao MV, Ahnert JR, Diao L, Wang J, Le X, Meric-Bernstam F, Routbort M, Roeck B, Yang Z, Raymond VM, Lanman RB, Frampton GM, Miller VA, Schrock AB, Albacker LA, Wong KK, Cross JB, Heymach JV.

Cancer Cell. 2019 Oct 14;36(4):444-457.e7. doi: 10.1016/j.ccell.2019.09.001. Epub 2019 Oct 3.

PMID:
31588020
2.

Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC.

Le X, Puri S, Negrao MV, Nilsson MB, Robichaux J, Boyle T, Hicks JK, Lovinger KL, Roarty E, Rinsurongkawong W, Tang M, Sun H, Elamin Y, Lacerda LC, Lewis J, Roth JA, Swisher SG, Lee JJ, William WN Jr, Glisson BS, Zhang J, Papadimitrakopoulou VA, Gray JE, Heymach JV.

Clin Cancer Res. 2018 Dec 15;24(24):6195-6203. doi: 10.1158/1078-0432.CCR-18-1542. Epub 2018 Sep 18.

PMID:
30228210
3.

Peatland vegetation composition and phenology drive the seasonal trajectory of maximum gross primary production.

Peichl M, Gažovič M, Vermeij I, de Goede E, Sonnentag O, Limpens J, Nilsson MB.

Sci Rep. 2018 May 22;8(1):8012. doi: 10.1038/s41598-018-26147-4.

4.

Partitioning of the net CO2 exchange using an automated chamber system reveals plant phenology as key control of production and respiration fluxes in a boreal peatland.

Järveoja J, Nilsson MB, Gažovič M, Crill PM, Peichl M.

Glob Chang Biol. 2018 Aug;24(8):3436-3451. doi: 10.1111/gcb.14292. Epub 2018 May 24.

PMID:
29710420
5.

Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer.

Robichaux JP, Elamin YY, Tan Z, Carter BW, Zhang S, Liu S, Li S, Chen T, Poteete A, Estrada-Bernal A, Le AT, Truini A, Nilsson MB, Sun H, Roarty E, Goldberg SB, Brahmer JR, Altan M, Lu C, Papadimitrakopoulou V, Politi K, Doebele RC, Wong KK, Heymach JV.

Nat Med. 2018 May;24(5):638-646. doi: 10.1038/s41591-018-0007-9. Epub 2018 Apr 23.

6.

Mercury evasion from a boreal peatland shortens the timeline for recovery from legacy pollution.

Osterwalder S, Bishop K, Alewell C, Fritsche J, Laudon H, Åkerblom S, Nilsson MB.

Sci Rep. 2017 Nov 22;7(1):16022. doi: 10.1038/s41598-017-16141-7.

7.

Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers.

Nilsson MB, Sun H, Diao L, Tong P, Liu D, Li L, Fan Y, Poteete A, Lim SO, Howells K, Haddad V, Gomez D, Tran H, Pena GA, Sequist LV, Yang JC, Wang J, Kim ES, Herbst R, Lee JJ, Hong WK, Wistuba I, Hung MC, Sood AK, Heymach JV.

Sci Transl Med. 2017 Nov 8;9(415). pii: eaao4307. doi: 10.1126/scitranslmed.aao4307. Erratum in: Sci Transl Med. 2019 May 22;11(493):.

8.

The Sphagnome Project: enabling ecological and evolutionary insights through a genus-level sequencing project.

Weston DJ, Turetsky MR, Johnson MG, Granath G, Lindo Z, Belyea LR, Rice SK, Hanson DT, Engelhardt KAM, Schmutz J, Dorrepaal E, Euskirchen ES, Stenøien HK, Szövényi P, Jackson M, Piatkowski BT, Muchero W, Norby RJ, Kostka JE, Glass JB, Rydin H, Limpens J, Tuittila ES, Ullrich KK, Carrell A, Benscoter BW, Chen JG, Oke TA, Nilsson MB, Ranjan P, Jacobson D, Lilleskov EA, Clymo RS, Shaw AJ.

New Phytol. 2018 Jan;217(1):16-25. doi: 10.1111/nph.14860. Epub 2017 Oct 27.

9.

Microbial mineralization of cellulose in frozen soils.

Segura JH, Nilsson MB, Haei M, Sparrman T, Mikkola JP, Gräsvik J, Schleucher J, Öquist MG.

Nat Commun. 2017 Oct 27;8(1):1154. doi: 10.1038/s41467-017-01230-y.

10.

Aquatic export of young dissolved and gaseous carbon from a pristine boreal fen: Implications for peat carbon stock stability.

Campeau A, Bishop KH, Billett MF, Garnett MH, Laudon H, Leach JA, Nilsson MB, Öquist MG, Wallin MB.

Glob Chang Biol. 2017 Dec;23(12):5523-5536. doi: 10.1111/gcb.13815. Epub 2017 Sep 1.

PMID:
28712133
11.

The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer.

Cascone T, Xu L, Lin HY, Liu W, Tran HT, Liu Y, Howells K, Haddad V, Hanrahan E, Nilsson MB, Cortez MA, Giri U, Kadara H, Saigal B, Park YY, Peng W, Lee JS, Ryan AJ, Jüergensmeier JM, Herbst RS, Wang J, Langley RR, Wistuba II, Lee JJ, Heymach JV.

Clin Cancer Res. 2017 Sep 15;23(18):5489-5501. doi: 10.1158/1078-0432.CCR-16-3216. Epub 2017 May 30.

12.

Terrestrial discharges mediate trophic shifts and enhance methylmercury accumulation in estuarine biota.

Jonsson S, Andersson A, Nilsson MB, Skyllberg U, Lundberg E, Schaefer JK, Åkerblom S, Björn E.

Sci Adv. 2017 Jan 27;3(1):e1601239. doi: 10.1126/sciadv.1601239. eCollection 2017 Jan.

13.

Long-term enhanced winter soil frost alters growing season CO2 fluxes through its impact on vegetation development in a boreal peatland.

Zhao J, Peichl M, Nilsson MB.

Glob Chang Biol. 2017 Aug;23(8):3139-3153. doi: 10.1111/gcb.13621. Epub 2017 Jan 31.

PMID:
28075520
14.

Including hydrological self-regulating processes in peatland models: Effects on peatmoss drought projections.

Nijp JJ, Metselaar K, Limpens J, Teutschbein C, Peichl M, Nilsson MB, Berendse F, van der Zee SEATM.

Sci Total Environ. 2017 Feb 15;580:1389-1400. doi: 10.1016/j.scitotenv.2016.12.104. Epub 2016 Dec 22.

PMID:
28012660
15.

Effects of Nutrient Loading and Mercury Chemical Speciation on the Formation and Degradation of Methylmercury in Estuarine Sediment.

Liem-Nguyen V, Jonsson S, Skyllberg U, Nilsson MB, Andersson A, Lundberg E, Björn E.

Environ Sci Technol. 2016 Jul 5;50(13):6983-90. doi: 10.1021/acs.est.6b01567. Epub 2016 Jun 20.

PMID:
27258391
16.

Gross primary production controls the subsequent winter CO2 exchange in a boreal peatland.

Zhao J, Peichl M, Öquist M, Nilsson MB.

Glob Chang Biol. 2016 Dec;22(12):4028-4037. doi: 10.1111/gcb.13308. Epub 2016 May 12. Review. Erratum in: Glob Chang Biol. 2017 May;23 (5):2140.

PMID:
27038205
17.

Detecting long-term metabolic shifts using isotopomers: CO2-driven suppression of photorespiration in C3 plants over the 20th century.

Ehlers I, Augusti A, Betson TR, Nilsson MB, Marshall JD, Schleucher J.

Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15585-90. doi: 10.1073/pnas.1504493112. Epub 2015 Dec 7.

18.

KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib.

Nilsson MB, Giri U, Gudikote J, Tang X, Lu W, Tran H, Fan Y, Koo A, Diao L, Tong P, Wang J, Herbst R, Johnson BE, Ryan A, Webster A, Rowe P, Wistuba II, Heymach JV.

Clin Cancer Res. 2016 Apr 15;22(8):1940-50. doi: 10.1158/1078-0432.CCR-15-1994. Epub 2015 Nov 17.

19.

Enhanced winter soil frost reduces methane emission during the subsequent growing season in a boreal peatland.

Zhao J, Peichl M, Nilsson MB.

Glob Chang Biol. 2016 Feb;22(2):750-62. doi: 10.1111/gcb.13119. Epub 2016 Jan 6.

PMID:
26452333
20.

Rain events decrease boreal peatland net CO2 uptake through reduced light availability.

Nijp JJ, Limpens J, Metselaar K, Peichl M, Nilsson MB, van der Zee SE, Berendse F.

Glob Chang Biol. 2015 Jun;21(6):2309-20. doi: 10.1111/gcb.12864. Epub 2015 Mar 6.

PMID:
25580711
21.

Differentiated availability of geochemical mercury pools controls methylmercury levels in estuarine sediment and biota.

Jonsson S, Skyllberg U, Nilsson MB, Lundberg E, Andersson A, Björn E.

Nat Commun. 2014 Aug 20;5:4624. doi: 10.1038/ncomms5624.

PMID:
25140406
22.

VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy.

Riquelme E, Suraokar M, Behrens C, Lin HY, Girard L, Nilsson MB, Simon G, Wang J, Coombes KR, Lee JJ, Hong WK, Heymach J, Minna JD, Wistuba II.

Clin Cancer Res. 2014 Jul 15;20(14):3849-61. doi: 10.1158/1078-0432.CCR-13-1916. Epub 2014 May 21.

23.

Temperature response of litter and soil organic matter decomposition is determined by chemical composition of organic material.

Erhagen B, Öquist M, Sparrman T, Haei M, Ilstedt U, Hedenström M, Schleucher J, Nilsson MB.

Glob Chang Biol. 2013 Dec;19(12):3858-71. doi: 10.1111/gcb.12342. Epub 2013 Oct 8.

PMID:
23907960
24.

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.

Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV.

Clin Cancer Res. 2013 Jan 1;19(1):279-90. doi: 10.1158/1078-0432.CCR-12-1558. Epub 2012 Oct 22.

25.

Mercury methylation rates for geochemically relevant Hg(II) species in sediments.

Jonsson S, Skyllberg U, Nilsson MB, Westlund PO, Shchukarev A, Lundberg E, Björn E.

Environ Sci Technol. 2012 Nov 6;46(21):11653-9. doi: 10.1021/es3015327. Epub 2012 Oct 25.

PMID:
23017152
26.

Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.

Byers LA, Wang J, Nilsson MB, Fujimoto J, Saintigny P, Yordy J, Giri U, Peyton M, Fan YH, Diao L, Masrorpour F, Shen L, Liu W, Duchemann B, Tumula P, Bhardwaj V, Welsh J, Weber S, Glisson BS, Kalhor N, Wistuba II, Girard L, Lippman SM, Mills GB, Coombes KR, Weinstein JN, Minna JD, Heymach JV.

Cancer Discov. 2012 Sep;2(9):798-811. doi: 10.1158/2159-8290.CD-12-0112. Epub 2012 Sep 6.

27.

Factors modulating cottongrass seedling growth stimulation to enhanced nitrogen and carbon dioxide: compensatory tradeoffs in leaf dynamics and allocation to meet potassium-limited growth.

Siegenthaler A, Buttler A, Grosvernier P, Gobat JM, Nilsson MB, Mitchell EA.

Oecologia. 2013 Feb;171(2):557-70. doi: 10.1007/s00442-012-2415-8. Epub 2012 Aug 19.

PMID:
22903550
28.

Glasshouse vs field experiments: do they yield ecologically similar results for assessing N impacts on peat mosses?

Limpens J, Granath G, Aerts R, Heijmans MM, Sheppard LJ, Bragazza L, Williams BL, Rydin H, Bubier J, Moore T, Rochefort L, Mitchell EA, Buttler A, van den Berg LJ, Gunnarsson U, Francez AJ, Gerdol R, Thormann M, Grosvernier P, Wiedermann MM, Nilsson MB, Hoosbeek MR, Bayley S, Nordbakken JF, Paulissen MP, Hotes S, Breeuwer A, Ilomets M, Tomassen HB, Leith I, Xu B.

New Phytol. 2012 Jul;195(2):408-18. doi: 10.1111/j.1469-8137.2012.04157.x. Epub 2012 Apr 26.

29.

Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy.

Yang F, Tang X, Riquelme E, Behrens C, Nilsson MB, Giri U, Varella-Garcia M, Byers LA, Lin HY, Wang J, Raso MG, Girard L, Coombes K, Lee JJ, Herbst RS, Minna JD, Heymach JV, Wistuba II.

Cancer Res. 2011 Aug 15;71(16):5512-21. doi: 10.1158/0008-5472.CAN-10-2614. Epub 2011 Jul 1.

30.

Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma.

Cascone T, Herynk MH, Xu L, Du Z, Kadara H, Nilsson MB, Oborn CJ, Park YY, Erez B, Jacoby JJ, Lee JS, Lin HY, Ciardiello F, Herbst RS, Langley RR, Heymach JV.

J Clin Invest. 2011 Apr;121(4):1313-28. doi: 10.1172/JCI42405. Epub 2011 Mar 23.

31.

Climatic modifiers of the response to nitrogen deposition in peat-forming Sphagnum mosses: a meta-analysis.

Limpens J, Granath G, Gunnarsson U, Aerts R, Bayley S, Bragazza L, Bubier J, Buttler A, van den Berg LJ, Francez AJ, Gerdol R, Grosvernier P, Heijmans MM, Hoosbeek MR, Hotes S, Ilomets M, Leith I, Mitchell EA, Moore T, Nilsson MB, Nordbakken JF, Rochefort L, Rydin H, Sheppard LJ, Thormann M, Wiedermann MM, Williams BL, Xu B.

New Phytol. 2011 Jul;191(2):496-507. doi: 10.1111/j.1469-8137.2011.03680.x. Epub 2011 Mar 22.

32.

Both catabolic and anabolic heterotrophic microbial activity proceed in frozen soils.

Drotz SH, Sparrman T, Nilsson MB, Schleucher J, Oquist MG.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21046-51. doi: 10.1073/pnas.1008885107. Epub 2010 Nov 15.

33.

Resource contrast in patterned peatlands increases along a climatic gradient.

Eppinga MB, Rietkerk M, Belyea LR, Nilsson MB, De Ruiter PC, Wassen MJ.

Ecology. 2010 Aug;91(8):2344-55.

PMID:
20836456
34.

Contrasting effects of wood ash application on microbial community structure, biomass and processes in drained forested peatlands.

Björk RG, Ernfors M, Sikström U, Nilsson MB, Andersson MX, Rütting T, Klemedtsson L.

FEMS Microbiol Ecol. 2010 Sep;73(3):550-62. doi: 10.1111/j.1574-6941.2010.00911.x. Epub 2010 May 14.

35.
36.

Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.

Nilsson MB, Zage PE, Zeng L, Xu L, Cascone T, Wu HK, Saigal B, Zweidler-McKay PA, Heymach JV.

Oncogene. 2010 May 20;29(20):2938-49. doi: 10.1038/onc.2010.60. Epub 2010 Mar 8.

PMID:
20208561
37.

Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells.

Xu L, Nilsson MB, Saintigny P, Cascone T, Herynk MH, Du Z, Nikolinakos PG, Yang Y, Prudkin L, Liu D, Lee JJ, Johnson FM, Wong KK, Girard L, Gazdar AF, Minna JD, Kurie JM, Wistuba II, Heymach JV.

Oncogene. 2010 May 6;29(18):2616-27. doi: 10.1038/onc.2010.16. Epub 2010 Feb 15.

38.

Depression of belowground respiration rates at simulated high moose population densities in boreal forests.

Persson IL, Nilsson MB, Pastor J, Eriksson T, Bergström R, Danell K.

Ecology. 2009 Oct;90(10):2724-33.

PMID:
19886482
39.

Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance.

Naumov GN, Nilsson MB, Cascone T, Briggs A, Straume O, Akslen LA, Lifshits E, Byers LA, Xu L, Wu HK, Jänne P, Kobayashi S, Halmos B, Tenen D, Tang XM, Engelman J, Yeap B, Folkman J, Johnson BE, Heymach JV.

Clin Cancer Res. 2009 May 15;15(10):3484-94. doi: 10.1158/1078-0432.CCR-08-2904. Epub 2009 May 15.

40.

Stress hormones regulate interleukin-6 expression by human ovarian carcinoma cells through a Src-dependent mechanism.

Nilsson MB, Armaiz-Pena G, Takahashi R, Lin YG, Trevino J, Li Y, Jennings N, Arevalo J, Lutgendorf SK, Gallick GE, Sanguino AM, Lopez-Berestein G, Cole SW, Sood AK.

J Biol Chem. 2007 Oct 12;282(41):29919-26. Epub 2007 Aug 23.

41.

Global change shifts vegetation and plant-parasite interactions in a boreal mire.

Wiedermann MM, Nordin A, Gunnarsson U, Nilsson MB, Ericson L.

Ecology. 2007 Feb;88(2):454-64. Erratum in: Ecology. 2007 Jul;88(7):1876.

PMID:
17479763
42.

Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine.

Nilsson MB, Langley RR, Fidler IJ.

Cancer Res. 2005 Dec 1;65(23):10794-800.

43.

Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.

Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, Gallick GE.

Cancer Res. 2005 Aug 15;65(16):7214-22.

44.

Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors.

Thaker PH, Yazici S, Nilsson MB, Yokoi K, Tsan RZ, He J, Kim SJ, Fidler IJ, Sood AK.

Clin Cancer Res. 2005 Jul 1;11(13):4923-33.

45.

Epidermal hyperplasia overlying human melanoma correlates with tumour depth and angiogenesis.

McCarty MF, Bielenberg DR, Nilsson MB, Gershenwald JE, Barnhill RL, Ahearne P, Bucana CD, Fidler IJ.

Melanoma Res. 2003 Aug;13(4):379-87.

PMID:
12883364
46.

Tissue-specific microvascular endothelial cell lines from H-2K(b)-tsA58 mice for studies of angiogenesis and metastasis.

Langley RR, Ramirez KM, Tsan RZ, Van Arsdall M, Nilsson MB, Fidler IJ.

Cancer Res. 2003 Jun 1;63(11):2971-6.

47.

[Letter: Further education in psychiatry].

Nordquist UB, Nilsson MB, Sullivan Y, Blomquist I.

Lakartidningen. 1975 Jun 11;72(24):2574. Swedish. No abstract available.

PMID:
1142882
48.

[Continued education in psychiatry].

Nordquist UB, Nilsson MB, Sullivan Y, Blomquist I.

Tidskr Sver Sjukskot. 1975 Feb 27;42(4):16. Swedish. No abstract available.

PMID:
1038243

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