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Supporting clinical decision making in advanced melanoma by preclinical testing in personalized immune-humanized xenograft mouse models.

Ny L, Rizzo LY, Belgrano V, Karlsson J, Jespersen H, Carstam L, Bagge RO, Nilsson LM, Nilsson JA.

Ann Oncol. 2020 Feb;31(2):266-273. doi: 10.1016/j.annonc.2019.11.002. Epub 2020 Jan 3.


Socioecological and biological associations of lower levels of physical activity in 8-year-old children: a 2-year prospective study.

Lahti A, Rosengren BE, Dencker M, Nilsson JÅ, Karlsson MK.

BMJ Open Sport Exerc Med. 2019 Nov 21;5(1):e000597. doi: 10.1136/bmjsem-2019-000597. eCollection 2019.


Incidence of Late-Diagnosed Hip Dislocation After Universal Clinical Screening in Sweden.

Wenger D, Düppe H, Nilsson JÅ, Tiderius CJ.

JAMA Netw Open. 2019 Nov 1;2(11):e1914779. doi: 10.1001/jamanetworkopen.2019.14779.


Endosomal signalling via exosome surface TGFβ-1.

Shelke GV, Yin Y, Jang SC, Lässer C, Wennmalm S, Hoffmann HJ, Li L, Gho YS, Nilsson JA, Lötvall J.

J Extracell Vesicles. 2019 Sep 20;8(1):1650458. doi: 10.1080/20013078.2019.1650458. eCollection 2019.


H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines.

Hofving T, Karlsson J, Nilsson O, Nilsson JA.

Nat Genet. 2019 Oct;51(10):1426-1427. doi: 10.1038/s41588-019-0490-z. No abstract available.


Malignancies in Giant Cell Arteritis: A Population-based Cohort Study.

Stamatis P, Turesson C, Willim M, Nilsson JÅ, Englund M, Mohammad AJ.

J Rheumatol. 2019 Jun 1. pii: jrheum.190236. doi: 10.3899/jrheum.190236. [Epub ahead of print]


Concomitant use of pembrolizumab and entinostat in adult patients with metastatic uveal melanoma (PEMDAC study): protocol for a multicenter phase II open label study.

Jespersen H, Olofsson Bagge R, Ullenhag G, Carneiro A, Helgadottir H, Ljuslinder I, Levin M, All-Eriksson C, Andersson B, Stierner U, Nilsson LM, Nilsson JA, Ny L.

BMC Cancer. 2019 May 2;19(1):415. doi: 10.1186/s12885-019-5623-3.


The fracture predictive ability of a musculoskeletal composite score in old men - data from the MrOs Sweden study.

Cronholm F, Rosengren BE, Nilsson JÅ, Ohlsson C, Mellström D, Ribom E, Karlsson MK.

BMC Geriatr. 2019 Mar 22;19(1):90. doi: 10.1186/s12877-019-1106-2.


Age-, gender- and family-related factors were the most important socio-ecological associations with physical activity in children with a mean age of eight years.

Lahti A, Rosengren BE, Nilsson JÅ, Peterson T, Karlsson MK.

Acta Paediatr. 2019 Mar 9. doi: 10.1111/apa.14776. [Epub ahead of print] No abstract available.


Clinical, genetic and experimental studies of the Brooke-Spiegler (CYLD) skin tumor syndrome.

Andersson MK, Kölby L, Nilsson JA, Stenman G.

J Plast Surg Hand Surg. 2019 Apr;53(2):71-75. doi: 10.1080/2000656X.2018.1547736. Epub 2019 Jan 24.


HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy-Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice.

Forsberg EMV, Lindberg MF, Jespersen H, Alsén S, Bagge RO, Donia M, Svane IM, Nilsson O, Ny L, Nilsson LM, Nilsson JA.

Cancer Res. 2019 Mar 1;79(5):899-904. doi: 10.1158/0008-5472.CAN-18-3158. Epub 2019 Jan 8.


Response and Toxicity of Repeated Isolated Limb Perfusion (re-ILP) for Patients With In-Transit Metastases of Malignant Melanoma.

Belgrano V, Pettersson J, Nilsson JA, Mattsson J, Katsarelias D, Olofsson Bagge R.

Ann Surg Oncol. 2019 Apr;26(4):1055-1062. doi: 10.1245/s10434-018-07143-4. Epub 2019 Jan 7.


Mass or pace? Seasonal energy management in wintering boreal passerines.

Broggi J, Nilsson JF, Koivula K, Hohtola E, Nilsson JÅ.

Oecologia. 2019 Feb;189(2):339-351. doi: 10.1007/s00442-018-04332-6. Epub 2019 Jan 7.


Age-dependent effects of predation risk on night-time hypothermia in two wintering passerine species.

Andreasson F, Nord A, Nilsson JÅ.

Oecologia. 2019 Feb;189(2):329-337. doi: 10.1007/s00442-018-04331-7. Epub 2019 Jan 3.


Immune function and blood parasite infections impact stopover ecology in passerine birds.

Hegemann A, Alcalde Abril P, Muheim R, Sjöberg S, Alerstam T, Nilsson JÅ, Hasselquist D.

Oecologia. 2018 Dec;188(4):1011-1024. doi: 10.1007/s00442-018-4291-3. Epub 2018 Nov 1.


Diet and ambient temperature interact to shape plasma fatty acid composition, basal metabolic rate and oxidative stress in great tits.

Andersson MN, Nilsson J, Nilsson JÅ, Isaksson C.

J Exp Biol. 2018 Dec 13;221(Pt 24). pii: jeb186759. doi: 10.1242/jeb.186759.


Mouse avatars take off as cancer models.

Nilsson JA, Olofsson Bagge R, Ny L.

Nature. 2018 Oct;562(7726):192. doi: 10.1038/d41586-018-06982-1. No abstract available.


Effects of interspecific coexistence on laying date and clutch size in two closely related species of hole-nesting birds.

Møller AP, Balbontín J, Dhondt AA, Remeš V, Adriaensen F, Biard C, Camprodon J, Cichoń M, Doligez B, Dubiec A, Eens M, Eeva T, Goodenough AE, Gosler AG, Gustafsson L, Heeb P, Hinsley SA, Jacob S, Juškaitis R, Laaksonen T, Leclercq B, Massa B, Mazgajski TD, Nager RG, Nilsson JÅ, Nilsson SG, Norte AC, Pinxten R, Robles H, Solonen T, Sorace A, van Noordwijk AJ, Lambrechts MM.

J Anim Ecol. 2018 Nov;87(6):1738-1748. doi: 10.1111/1365-2656.12896. Epub 2018 Sep 10.


A mimicked bacterial infection prolongs stopover duration in songbirds-but more pronounced in short- than long-distance migrants.

Hegemann A, Alcalde Abril P, Sjöberg S, Muheim R, Alerstam T, Nilsson JÅ, Hasselquist D.

J Anim Ecol. 2018 Nov;87(6):1698-1708. doi: 10.1111/1365-2656.12895. Epub 2018 Aug 28.


A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma.

Einarsdottir BO, Karlsson J, Söderberg EMV, Lindberg MF, Funck-Brentano E, Jespersen H, Brynjolfsson SF, Bagge RO, Carstam L, Scobie M, Koolmeister T, Wallner O, Stierner U, Berglund UW, Ny L, Nilsson LM, Larsson E, Helleday T, Nilsson JA.

Cell Death Dis. 2018 Jul 24;9(8):810. doi: 10.1038/s41419-018-0865-6.


Anti-Leukemic Properties of Histamine in Monocytic Leukemia: The Role of NOX2.

Kiffin R, Grauers Wiktorin H, Nilsson MS, Aurelius J, Aydin E, Lenox B, Nilsson JA, Ståhlberg A, Thorén FB, Hellstrand K, Martner A.

Front Oncol. 2018 Jun 18;8:218. doi: 10.3389/fonc.2018.00218. eCollection 2018.


Testing the heat dissipation limit theory in a breeding passerine.

Nilsson JÅ, Nord A.

Proc Biol Sci. 2018 May 16;285(1878). pii: 20180652. doi: 10.1098/rspb.2018.0652.


Smoking, body mass index, disease activity, and the risk of rapid radiographic progression in patients with early rheumatoid arthritis.

Rydell E, Forslind K, Nilsson JÅ, Jacobsson LTH, Turesson C.

Arthritis Res Ther. 2018 May 2;20(1):82. doi: 10.1186/s13075-018-1575-2.


Long-term effects of daily physical education throughout compulsory school on duration of physical activity in young adulthood: an 11-year prospective controlled study.

Lahti A, Rosengren BE, Nilsson JÅ, Karlsson C, Karlsson MK.

BMJ Open Sport Exerc Med. 2018 Apr 10;4(1):e000360. doi: 10.1136/bmjsem-2018-000360. eCollection 2018.


The evolution of immunity in relation to colonization and migration.

O'Connor EA, Cornwallis CK, Hasselquist D, Nilsson JÅ, Westerdahl H.

Nat Ecol Evol. 2018 May;2(5):841-849. doi: 10.1038/s41559-018-0509-3. Epub 2018 Apr 9.


BET bromodomain inhibitors synergize with ATR inhibitors in melanoma.

Veppil Muralidharan S, Osk Einarsdottir B, Bhadury J, Lindberg MF, Wu J, Campeau E, Olofsson Bagge R, Stierner U, Ny L, Nilsson LM, Nilsson JA.

Cell Death Dis. 2017 Dec 14;8(12):e3177. doi: 10.1038/cddis.2017.557.


Pathogenesis and therapeutic targeting of aberrant MYC expression in haematological cancers.

Schick M, Habringer S, Nilsson JA, Keller U.

Br J Haematol. 2017 Dec;179(5):724-738. doi: 10.1111/bjh.14917. Epub 2017 Nov 24. Review.


The use of the nest for parental roosting and thermal consequences of the nest for nestlings and parents.

Nilsson JÅ, Nord A.

Behav Ecol Sociobiol. 2017;71(12):171. doi: 10.1007/s00265-017-2400-7. Epub 2017 Nov 7.


Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model.

Jespersen H, Lindberg MF, Donia M, Söderberg EMV, Andersen R, Keller U, Ny L, Svane IM, Nilsson LM, Nilsson JA.

Nat Commun. 2017 Sep 27;8(1):707. doi: 10.1038/s41467-017-00786-z.


Low physical activity is related to clustering of risk factors for fracture-a 2-year prospective study in children.

Stenevi Lundgren S, Rosengren BE, Dencker M, Nilsson JÅ, Karlsson C, Karlsson MK.

Osteoporos Int. 2017 Dec;28(12):3373-3378. doi: 10.1007/s00198-017-4203-0. Epub 2017 Sep 15.


BET bromodomain inhibitors synergize with ATR inhibitors in melanoma.

Muralidharan SV, Einarsdottir BO, Bhadury J, Lindberg MF, Wu J, Campeau E, Bagge RO, Stierner U, Ny L, Nilsson LM, Nilsson JA.

Cell Death Dis. 2017 Aug 10;8(8):e2982. doi: 10.1038/cddis.2017.383. Erratum in: Cell Death Dis. 2017 Dec 14;8(12 ):e3177.


Adaptive temperature regulation in the little bird in winter: predictions from a stochastic dynamic programming model.

Brodin A, Nilsson JÅ, Nord A.

Oecologia. 2017 Sep;185(1):43-54. doi: 10.1007/s00442-017-3923-3. Epub 2017 Aug 3.


Severe Infection in Antineutrophil Cytoplasmic Antibody-associated Vasculitis.

Mohammad AJ, Segelmark M, Smith R, Englund M, Nilsson JÅ, Westman K, Merkel PA, Jayne DRW.

J Rheumatol. 2017 Oct;44(10):1468-1475. doi: 10.3899/jrheum.160909. Epub 2017 Aug 1.


BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.

Lunavat TR, Cheng L, Einarsdottir BO, Olofsson Bagge R, Veppil Muralidharan S, Sharples RA, Lässer C, Gho YS, Hill AF, Nilsson JA, Lötvall J.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5930-E5939. doi: 10.1073/pnas.1705206114. Epub 2017 Jul 6.


Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.

Donia M, Harbst K, van Buuren M, Kvistborg P, Lindberg MF, Andersen R, Idorn M, Munir Ahmad S, Ellebæk E, Mueller A, Fagone P, Nicoletti F, Libra M, Lauss M, Hadrup SR, Schmidt H, Andersen MH, Thor Straten P, Nilsson JA, Schumacher TN, Seliger B, Jönsson G, Svane IM.

Cancer Res. 2017 Sep 1;77(17):4562-4566. doi: 10.1158/0008-5472.CAN-16-3172. Epub 2017 Jun 27.


Time trends in pediatric fracture incidence in Sweden during the period 1950-2006.

Lempesis V, Rosengren BE, Nilsson JÅ, Landin L, Tiderius CJ, Karlsson MK.

Acta Orthop. 2017 Aug;88(4):440-445. doi: 10.1080/17453674.2017.1334284. Epub 2017 May 31.


Severe Extraarticular Manifestations in a Community-based Cohort of Patients with Rheumatoid Arthritis: Risk Factors and Incidence in Relation to Treatment with Tumor Necrosis Factor Inhibitors.

Theander L, Nyhäll-Wåhlin BM, Nilsson JÅ, Willim M, Jacobsson LTH, Petersson IF, Turesson C.

J Rheumatol. 2017 Jul;44(7):981-987. doi: 10.3899/jrheum.161103. Epub 2017 May 1.


Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.

Gad H, Koolmeister T, Jemth AS, Eshtad S, Jacques SA, Ström CE, Svensson LM, Schultz N, Lundbäck T, Einarsdottir BO, Saleh A, Göktürk C, Baranczewski P, Svensson R, Berntsson RP, Gustafsson R, Strömberg K, Sanjiv K, Jacques-Cordonnier MC, Desroses M, Gustavsson AL, Olofsson R, Johansson F, Homan EJ, Loseva O, Bräutigam L, Johansson L, Höglund A, Hagenkort A, Pham T, Altun M, Gaugaz FZ, Vikingsson S, Evers B, Henriksson M, Vallin KSA, Wallner OA, Hammarström LGJ, Wiita E, Almlöf I, Kalderén C, Axelsson H, Djureinovic T, Carreras Puigvert J, Häggblad M, Jeppsson F, Martens U, Lundin C, Lundgren B, Granelli I, Jenmalm Jensen A, Artursson P, Nilsson JA, Stenmark P, Scobie M; Ulrika Warpman Berglund &Thomas Helleday.

Nature. 2017 Apr 26;544(7651):508. doi: 10.1038/nature22083. No abstract available.


Treatment with belimumab in systemic lupus erythematosus does not impair antibody response to 13-valent pneumococcal conjugate vaccine.

Nagel J, Saxne T, Geborek P, Bengtsson AA, Jacobsen S, Svaerke Joergensen C, Nilsson JÅ, Skattum L, Jönsen A, Kapetanovic MC.

Lupus. 2017 Sep;26(10):1072-1081. doi: 10.1177/0961203317695465. Epub 2017 Feb 26.


How does a physical activity programme in elementary school affect fracture risk? A prospective controlled intervention study in Malmo, Sweden.

Cöster ME, Fritz J, Nilsson JÅ, Karlsson C, Rosengren BE, Dencker M, Karlsson MK.

BMJ Open. 2017 Feb 23;7(2):e012513. doi: 10.1136/bmjopen-2016-012513.


Risk factors for low back pain and sciatica in elderly men-the MrOS Sweden study.

Kherad M, Rosengren BE, Hasserius R, Nilsson JÅ, Redlund-Johnell I, Ohlsson C, Mellström D, Lorentzon M, Ljunggren Ö, Karlsson MK.

Age Ageing. 2017 Jan 8;46(1):64-71. doi: 10.1093/ageing/afw152.


Predictors of work disability after start of anti-TNF therapy in a national cohort of Swedish patients with rheumatoid arthritis: does early anti-TNF therapy bring patients back to work?

Olofsson T, Petersson IF, Eriksson JK, Englund M, Nilsson JA, Geborek P, Jacobsson LTH, Askling J, Neovius M; ARTIS Study Group.

Ann Rheum Dis. 2017 Jul;76(7):1245-1252. doi: 10.1136/annrheumdis-2016-210239. Epub 2017 Jan 10.


Complement peptide C3a stimulates neural plasticity after experimental brain ischaemia.

Stokowska A, Atkins AL, Morán J, Pekny T, Bulmer L, Pascoe MC, Barnum SR, Wetsel RA, Nilsson JA, Dragunow M, Pekna M.

Brain. 2017 Feb;140(2):353-369. doi: 10.1093/brain/aww314. Epub 2016 Dec 12.


Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers.

Alaei-Mahabadi B, Bhadury J, Karlsson JW, Nilsson JA, Larsson E.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13768-13773. Epub 2016 Nov 16.


Validation and development of MTH1 inhibitors for treatment of cancer.

Warpman Berglund U, Sanjiv K, Gad H, Kalderén C, Koolmeister T, Pham T, Gokturk C, Jafari R, Maddalo G, Seashore-Ludlow B, Chernobrovkin A, Manoilov A, Pateras IS, Rasti A, Jemth AS, Almlöf I, Loseva O, Visnes T, Einarsdottir BO, Gaugaz FZ, Saleh A, Platzack B, Wallner OA, Vallin KS, Henriksson M, Wakchaure P, Borhade S, Herr P, Kallberg Y, Baranczewski P, Homan EJ, Wiita E, Nagpal V, Meijer T, Schipper N, Rudd SG, Bräutigam L, Lindqvist A, Filppula A, Lee TC, Artursson P, Nilsson JA, Gorgoulis VG, Lehtiö J, Zubarev RA, Scobie M, Helleday T.

Ann Oncol. 2016 Dec;27(12):2275-2283. doi: 10.1093/annonc/mdw429. Epub 2016 Nov 8.


Energy Reserves, Information Need and a Pinch of Personality Determine Decision-Making on Route in Partially Migratory Blue Tits.

Nilsson AL, Nilsson JÅ, Mettke-Hofmann C.

PLoS One. 2016 Oct 12;11(10):e0163213. doi: 10.1371/journal.pone.0163213. eCollection 2016.


The effect of clinical features and glucocorticoids on biopsy findings in giant cell arteritis.

Jakobsson K, Jacobsson L, Mohammad AJ, Nilsson JÅ, Warrington K, Matteson EL, Turesson C.

BMC Musculoskelet Disord. 2016 Aug 24;17(1):363. doi: 10.1186/s12891-016-1225-2.


Body Temperature Regulation in Hot Environments.

Nilsson JÅ, Molokwu MN, Olsson O.

PLoS One. 2016 Aug 22;11(8):e0161481. doi: 10.1371/journal.pone.0161481. eCollection 2016.


Interspecific variation in the relationship between clutch size, laying date and intensity of urbanization in four species of hole-nesting birds.

Vaugoyeau M, Adriaensen F, Artemyev A, Bańbura J, Barba E, Biard C, Blondel J, Bouslama Z, Bouvier JC, Camprodon J, Cecere F, Charmantier A, Charter M, Cichoń M, Cusimano C, Czeszczewik D, Demeyrier V, Doligez B, Doutrelant C, Dubiec A, Eens M, Eeva T, Faivre B, Ferns PN, Forsman JT, García-Del-Rey E, Goldshtein A, Goodenough AE, Gosler AG, Grégoire A, Gustafsson L, Harnist I, Hartley IR, Heeb P, Hinsley SA, Isenmann P, Jacob S, Juškaitis R, Korpimäki E, Krams I, Laaksonen T, Lambrechts MM, Leclercq B, Lehikoinen E, Loukola O, Lundberg A, Mainwaring MC, Mänd R, Massa B, Mazgajski TD, Merino S, Mitrus C, Mönkkönen M, Morin X, Nager RG, Nilsson JÅ, Nilsson SG, Norte AC, Orell M, Perret P, Perrins CM, Pimentel CS, Pinxten R, Richner H, Robles H, Rytkönen S, Senar JC, Seppänen JT, Pascoal da Silva L, Slagsvold T, Solonen T, Sorace A, Stenning MJ, Tryjanowski P, von Numers M, Walankiewicz W, Møller AP.

Ecol Evol. 2016 Jul 25;6(16):5907-20. doi: 10.1002/ece3.2335. eCollection 2016 Aug.


Brood size constrains the development of endothermy in blue tits.

Andreasson F, Nord A, Nilsson JÅ.

J Exp Biol. 2016 Jul 15;219(Pt 14):2212-9. doi: 10.1242/jeb.135350.

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