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Items: 24


Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer.

Korobeynikov V, Borakove M, Feng Y, Wuest WM, Koval AB, Nikonova AS, Serebriiskii I, Chernoff J, Borges VF, Golemis EA, Shagisultanova E.

Breast Cancer Res Treat. 2019 Jun 28. doi: 10.1007/s10549-019-05329-2. [Epub ahead of print]


Unexpected Activities in Regulating Ciliation Contribute to Off-target Effects of Targeted Drugs.

Kiseleva AA, Korobeynikov VA, Nikonova AS, Zhang P, Makhov P, Deneka AY, Einarson MB, Serebriiskii IG, Liu H, Peterson JR, Golemis EA.

Clin Cancer Res. 2019 Jul 1;25(13):4179-4193. doi: 10.1158/1078-0432.CCR-18-3535. Epub 2019 Mar 13.


Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD).

Nikonova AS, Deneka AY, Kiseleva AA, Korobeynikov V, Gaponova A, Serebriiskii IG, Kopp MC, Hensley HH, Seeger-Nukpezah TN, Somlo S, Proia DA, Golemis EA.

FASEB J. 2018 May;32(5):2735-2746. doi: 10.1096/fj.201700909R. Epub 2018 Jan 10.


Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.

Deneka AY, Haber L, Kopp MC, Gaponova AV, Nikonova AS, Golemis EA.

PLoS One. 2017 Apr 28;12(4):e0176747. doi: 10.1371/journal.pone.0176747. eCollection 2017.


Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin.

Gaponova AV, Deneka AY, Beck TN, Liu H, Andrianov G, Nikonova AS, Nicolas E, Einarson MB, Golemis EA, Serebriiskii IG.

Oncotarget. 2017 Mar 21;8(12):19156-19171. doi: 10.18632/oncotarget.13353.


Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis.

Kudinov AE, Deneka A, Nikonova AS, Beck TN, Ahn YH, Liu X, Martinez CF, Schultz FA, Reynolds S, Yang DH, Cai KQ, Yaghmour KM, Baker KA, Egleston BL, Nicolas E, Chikwem A, Andrianov G, Singh S, Borghaei H, Serebriiskii IG, Gibbons DL, Kurie JM, Golemis EA, Boumber Y.

Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6955-60. doi: 10.1073/pnas.1513616113. Epub 2016 Jun 6.


A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer.

Gaponova AV, Nikonova AS, Deneka A, Kopp MC, Kudinov AE, Skobeleva N, Khazak V, Ogawa LS, Cai KQ, Duncan KE, Duncan JS, Egleston BL, Proia DA, Boumber Y, Golemis EA.

Clin Cancer Res. 2016 Oct 15;22(20):5120-5129. doi: 10.1158/1078-0432.CCR-15-3068. Epub 2016 Jun 7.


Taking Snapshots of Ciliary Signaling.

Nikonova AS, Golemis EA.

Dev Cell. 2015 Nov 23;35(4):399-400. doi: 10.1016/j.devcel.2015.11.006.


Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease.

Nikonova AS, Deneka AY, Eckman L, Kopp MC, Hensley HH, Egleston BL, Golemis EA.

Front Oncol. 2015 Oct 16;5:228. doi: 10.3389/fonc.2015.00228. eCollection 2015.


The tumor suppressor FBW7 controls ciliary length.

Nikonova AS, Golemis EA.

EMBO J. 2015 Oct 1;34(19):2388-90. doi: 10.15252/embj.201592588. Epub 2015 Aug 12. No abstract available.


Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization.

Ramirez UD, Nikonova AS, Liu H, Pecherskaya A, Lawrence SH, Serebriiskii IG, Zhou Y, Robinson MK, Einarson MB, Golemis EA, Jaffe EK.

BMC Cancer. 2015 May 28;15:436. doi: 10.1186/s12885-015-1415-6.


The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease.

Seeger-Nukpezah T, Geynisman DM, Nikonova AS, Benzing T, Golemis EA.

Nat Rev Nephrol. 2015 Sep;11(9):515-34. doi: 10.1038/nrneph.2015.46. Epub 2015 Apr 14. Review.


Control of ciliation in embryogenesis.

Nikonova AS, Golemis EA.

Nat Cell Biol. 2015 Feb;17(2):109-11. doi: 10.1038/ncb3103.


Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice.

Smithline ZB, Nikonova AS, Hensley HH, Cai KQ, Egleston BL, Proia DA, Seeger-Nukpezah T, Golemis EA.

PLoS One. 2014 Dec 4;9(12):e114403. doi: 10.1371/journal.pone.0114403. eCollection 2014.


Nedd9 restrains renal cystogenesis in Pkd1-/- mice.

Nikonova AS, Plotnikova OV, Serzhanova V, Efimov A, Bogush I, Cai KQ, Hensley HH, Egleston BL, Klein-Szanto A, Seeger-Nukpezah T, Golemis EA.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12859-64. doi: 10.1073/pnas.1405362111. Epub 2014 Aug 19.


CAS proteins in health and disease: an update.

Nikonova AS, Gaponova AV, Kudinov AE, Golemis EA.

IUBMB Life. 2014 Jun;66(6):387-95. doi: 10.1002/iub.1282. Epub 2014 Jun 24. Review.


Quantification of excision repair cross-complementing group 1 and survival in p16-negative squamous cell head and neck cancers.

Mehra R, Zhu F, Yang DH, Cai KQ, Weaver J, Singh MK, Nikonova AS, Golemis EA, Flieder DB, Cooper HS, Lango M, Ridge JA, Burtness B.

Clin Cancer Res. 2013 Dec 1;19(23):6633-43. doi: 10.1158/1078-0432.CCR-13-0152. Epub 2013 Oct 2.


Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.

Seeger-Nukpezah T, Proia DA, Egleston BL, Nikonova AS, Kent T, Cai KQ, Hensley HH, Ying W, Chimmanamada D, Serebriiskii IG, Golemis EA.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12786-91. doi: 10.1073/pnas.1301904110. Epub 2013 Jul 15.


Aurora A kinase (AURKA) in normal and pathological cell division.

Nikonova AS, Astsaturov I, Serebriiskii IG, Dunbrack RL Jr, Golemis EA.

Cell Mol Life Sci. 2013 Feb;70(4):661-87. doi: 10.1007/s00018-012-1073-7. Epub 2012 Aug 3. Review.


Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis.

Plotnikova OV, Nikonova AS, Loskutov YV, Kozyulina PY, Pugacheva EN, Golemis EA.

Mol Biol Cell. 2012 Jul;23(14):2658-70. doi: 10.1091/mbc.E11-12-1056. Epub 2012 May 23.


[Recognition receptors of innate immunity (NLR, RLr, and CLR)].

Koval'chuk DV, Khoreva MV, Nikonova AS.

Zh Mikrobiol Epidemiol Immunobiol. 2011 Jan-Feb;(1):93-100. Review. Russian.


[Antimediatory therapy in the complex treatment of acute destructive pancreatitis].

Gorskiĭ VA, Koval'chuk LV, Agapov MA, Khoreva MV, Ovanesian ER, Nikonova AS, Grechenko VV.

Khirurgiia (Mosk). 2010;(3):54-61. Russian. No abstract available.


[Toll-like receptor-mediated functional activity of mononuclear cells in children with neutropenia].

Koval'chuk LV, Khoreva MV, Nikonova AS, Finogenova NA, Mamedova EA, Polovtseva TV, Fetisova LIa, Gracheva LA, Goldyreva NG.

Zh Mikrobiol Epidemiol Immunobiol. 2010 Mar-Apr;(2):64-8. Russian.


[Corrective effect of cyclooxygenase inhibitor on functional status of mononuclear cells expressing Toll-like receptors].

Koval'chuk LV, Khoreva MV, Nikonova AS, Grechenko VV, Agapov MA, Indarokov VA, Leonenko IV, Gorskiĭ VA, Gracheva LA.

Zh Mikrobiol Epidemiol Immunobiol. 2010 Jan-Feb;(1):45-50. Russian.


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