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Extensions of the probabilistic ranking metrics of competing treatments in network meta-analysis to reflect clinically important relative differences on many outcomes.

Mavridis D, Porcher R, Nikolakopoulou A, Salanti G, Ravaud P.

Biom J. 2019 Oct 29. doi: 10.1002/bimj.201900026. [Epub ahead of print]


Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis.

Siontis GCM, Overtchouk P, Cahill TJ, Modine T, Prendergast B, Praz F, Pilgrim T, Petrinic T, Nikolakopoulou A, Salanti G, Søndergaard L, Verma S, Jüni P, Windecker S.

Eur Heart J. 2019 Oct 7;40(38):3143-3153. doi: 10.1093/eurheartj/ehz275.


Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis.

Huhn M, Nikolakopoulou A, Schneider-Thoma J, Krause M, Samara M, Peter N, Arndt T, Bäckers L, Rothe P, Cipriani A, Davis J, Salanti G, Leucht S.

Lancet. 2019 Sep 14;394(10202):939-951. doi: 10.1016/S0140-6736(19)31135-3. Epub 2019 Jul 11. Erratum in: Lancet. 2019 Sep 14;394(10202):918.


Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.

Nikolakopoulou AM, Montagne A, Kisler K, Dai Z, Wang Y, Huuskonen MT, Sagare AP, Lazic D, Sweeney MD, Kong P, Wang M, Owens NC, Lawson EJ, Xie X, Zhao Z, Zlokovic BV.

Nat Neurosci. 2019 Jul;22(7):1089-1098. doi: 10.1038/s41593-019-0434-z. Epub 2019 Jun 24.


Synthesizing existing evidence to design future trials: survey of methodologists from European institutions.

Nikolakopoulou A, Trelle S, Sutton AJ, Egger M, Salanti G.

Trials. 2019 Jun 7;20(1):334. doi: 10.1186/s13063-019-3449-6.


3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice.

Lazic D, Sagare AP, Nikolakopoulou AM, Griffin JH, Vassar R, Zlokovic BV.

J Exp Med. 2019 Feb 4;216(2):279-293. doi: 10.1084/jem.20181035. Epub 2019 Jan 15.


Client feedback in psychological therapy for children and adolescents with mental health problems.

Bergman H, Kornør H, Nikolakopoulou A, Hanssen-Bauer K, Soares-Weiser K, Tollefsen TK, Bjørndal A.

Cochrane Database Syst Rev. 2018 Aug 20;8:CD011729. doi: 10.1002/14651858.CD011729.pub2.


Planning a future randomized clinical trial based on a network of relevant past trials.

Salanti G, Nikolakopoulou A, Sutton AJ, Reichenbach S, Trelle S, Naci H, Egger M.

Trials. 2018 Jul 11;19(1):365. doi: 10.1186/s13063-018-2740-2.


How Many Patients With Schizophrenia Do Not Respond to Antipsychotic Drugs in the Short Term? An Analysis Based on Individual Patient Data From Randomized Controlled Trials.

Samara MT, Nikolakopoulou A, Salanti G, Leucht S.

Schizophr Bull. 2019 Apr 25;45(3):639-646. doi: 10.1093/schbul/sby095.


Documentation of a New Intracavitary Applicator for Transrectal Hyperthermia Designed for Prostate Cancer Cases: A Phantom Study.

Kouloulias V, Nikolakopoulou A, Karanasiou I, Antypas C, Armpilia C, Uzunoglou N.

J Med Phys. 2018 Apr-Jun;43(2):141-145. doi: 10.4103/jmp.JMP_67_17.


Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus.

Koeppen J, Nguyen AQ, Nikolakopoulou AM, Garcia M, Hanna S, Woodruff S, Figueroa Z, Obenaus A, Ethell IM.

J Neurosci. 2018 Jun 20;38(25):5710-5726. doi: 10.1523/JNEUROSCI.3618-17.2018. Epub 2018 May 23.


Estimating the contribution of studies in network meta-analysis: paths, flows and streams.

Papakonstantinou T, Nikolakopoulou A, Rücker G, Chaimani A, Schwarzer G, Egger M, Salanti G.

Version 3. F1000Res. 2018 May 18 [revised 2018 Jan 1];7:610. doi: 10.12688/f1000research.14770.3. eCollection 2018.


Living network meta-analysis compared with pairwise meta-analysis in comparative effectiveness research: empirical study.

Nikolakopoulou A, Mavridis D, Furukawa TA, Cipriani A, Tricco AC, Straus SE, Siontis GCM, Egger M, Salanti G.

BMJ. 2018 Feb 28;360:k585. doi: 10.1136/bmj.k585. Review.


Outcomes of non-invasive diagnostic modalities for the detection of coronary artery disease: network meta-analysis of diagnostic randomised controlled trials.

Siontis GC, Mavridis D, Greenwood JP, Coles B, Nikolakopoulou A, Jüni P, Salanti G, Windecker S.

BMJ. 2018 Feb 21;360:k504. doi: 10.1136/bmj.k504. Review.


Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.

Montagne A, Nikolakopoulou AM, Zhao Z, Sagare AP, Si G, Lazic D, Barnes SR, Daianu M, Ramanathan A, Go A, Lawson EJ, Wang Y, Mack WJ, Thompson PM, Schneider JA, Varkey J, Langen R, Mullins E, Jacobs RE, Zlokovic BV.

Nat Med. 2018 Mar;24(3):326-337. doi: 10.1038/nm.4482. Epub 2018 Feb 5.


Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis.

Krause M, Zhu Y, Huhn M, Schneider-Thoma J, Bighelli I, Nikolakopoulou A, Leucht S.

Eur Arch Psychiatry Clin Neurosci. 2018 Oct;268(7):625-639. doi: 10.1007/s00406-018-0869-3. Epub 2018 Jan 24. Review.


Comparative efficacy and acceptability of pharmacological treatments for post-traumatic stress disorder in adults: a network meta-analysis.

Cipriani A, Williams T, Nikolakopoulou A, Salanti G, Chaimani A, Ipser J, Cowen PJ, Geddes JR, Stein DJ.

Psychol Med. 2018 Sep;48(12):1975-1984. doi: 10.1017/S003329171700349X. Epub 2017 Dec 19.


A model for meta-analysis of correlated binary outcomes: The case of split-body interventions.

Efthimiou O, Mavridis D, Nikolakopoulou A, Rücker G, Trelle S, Egger M, Salanti G.

Stat Methods Med Res. 2019 Jul;28(7):1998-2014. doi: 10.1177/0962280217746436. Epub 2017 Dec 12.


Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea.

Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA.

PLoS Genet. 2017 Oct 23;13(10):e1007048. doi: 10.1371/journal.pgen.1007048. eCollection 2017 Oct.


Systematic review of interventions for treating or preventing antipsychotic-induced tardive dyskinesia.

Bergman H, Walker DM, Nikolakopoulou A, Soares-Weiser K, Adams CE.

Health Technol Assess. 2017 Aug;21(43):1-218. doi: 10.3310/hta21430. Review.


An investigation of the impact of using different methods for network meta-analysis: a protocol for an empirical evaluation.

Karahalios AE, Salanti G, Turner SL, Herbison GP, White IR, Veroniki AA, Nikolakopoulou A, Mckenzie JE.

Syst Rev. 2017 Jun 24;6(1):119. doi: 10.1186/s13643-017-0511-x.


Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling.

Nikolakopoulou AM, Zhao Z, Montagne A, Zlokovic BV.

PLoS One. 2017 Apr 25;12(4):e0176225. doi: 10.1371/journal.pone.0176225. eCollection 2017.


Erratum to: Characteristics and knowledge synthesis approach for 456 network meta-analyses: a scoping review.

Zarin W, Veroniki AA, Nincic V, Vafaei A, Reynen E, Motiwala SS, Antony J, Sullivan SM, Rios P, Daly C, Ewusie J, Petropoulou M, Nikolakopoulou A, Chaimani A, Salanti G, Straus SE, Tricco AC.

BMC Med. 2017 Mar 14;15(1):61. doi: 10.1186/s12916-017-0832-6. No abstract available.


Characteristics and knowledge synthesis approach for 456 network meta-analyses: a scoping review.

Zarin W, Veroniki AA, Nincic V, Vafaei A, Reynen E, Motiwala SS, Antony J, Sullivan SM, Rios P, Daly C, Ewusie J, Petropoulou M, Nikolakopoulou A, Chaimani A, Salanti G, Straus SE, Tricco AC.

BMC Med. 2017 Jan 5;15(1):3. doi: 10.1186/s12916-016-0764-6. Erratum in: BMC Med. 2017 Mar 14;15(1):61.


Bibliographic study showed improving statistical methodology of network meta-analyses published between 1999 and 2015.

Petropoulou M, Nikolakopoulou A, Veroniki AA, Rios P, Vafaei A, Zarin W, Giannatsi M, Sullivan S, Tricco AC, Chaimani A, Egger M, Salanti G.

J Clin Epidemiol. 2017 Feb;82:20-28. doi: 10.1016/j.jclinepi.2016.11.002. Epub 2016 Nov 15. Review.


Continuously updated network meta-analysis and statistical monitoring for timely decision-making.

Nikolakopoulou A, Mavridis D, Egger M, Salanti G.

Stat Methods Med Res. 2018 May;27(5):1312-1330. doi: 10.1177/0962280216659896. Epub 2016 Sep 1.


Presenilin 1 promotes trypsin-induced neuroprotection via the PAR2/ERK signaling pathway. Effects of presenilin 1 FAD mutations.

Nikolakopoulou AM, Georgakopoulos A, Robakis NK.

Neurobiol Aging. 2016 Jun;42:41-9. doi: 10.1016/j.neurobiolaging.2016.02.028. Epub 2016 Mar 4.


Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury.

Nikolakopoulou AM, Koeppen J, Garcia M, Leish J, Obenaus A, Ethell IM.

ASN Neuro. 2016 Feb 29;8(1):1-18. doi: 10.1177/1759091416630220. Print 2016 Jan-Feb.


Efficacy, Acceptability, and Tolerability of Antipsychotics in Treatment-Resistant Schizophrenia: A Network Meta-analysis.

Samara MT, Dold M, Gianatsi M, Nikolakopoulou A, Helfer B, Salanti G, Leucht S.

JAMA Psychiatry. 2016 Mar;73(3):199-210. doi: 10.1001/jamapsychiatry.2015.2955.


Endoscopic and Open Release Similarly Safe for the Treatment of Carpal Tunnel Syndrome. A Systematic Review and Meta-Analysis.

Vasiliadis HS, Nikolakopoulou A, Shrier I, Lunn MP, Brassington R, Scholten RJ, Salanti G.

PLoS One. 2015 Dec 16;10(12):e0143683. doi: 10.1371/journal.pone.0143683. eCollection 2015. Review.


Planning future studies based on the precision of network meta-analysis results.

Nikolakopoulou A, Mavridis D, Salanti G.

Stat Med. 2016 Mar 30;35(7):978-1000. doi: 10.1002/sim.6608. Epub 2015 Aug 6.


Using conditional power of network meta-analysis (NMA) to inform the design of future clinical trials.

Nikolakopoulou A, Mavridis D, Salanti G.

Biom J. 2014 Nov;56(6):973-90. doi: 10.1002/bimj.201300216. Epub 2014 Sep 16.


How to interpret meta-analysis models: fixed effect and random effects meta-analyses.

Nikolakopoulou A, Mavridis D, Salanti G.

Evid Based Ment Health. 2014 May;17(2):64. doi: 10.1136/eb-2014-101794.


Demystifying fixed and random effects meta-analysis.

Nikolakopoulou A, Mavridis D, Salanti G.

Evid Based Ment Health. 2014 May;17(2):53-7. doi: 10.1136/eb-2014-101795. Epub 2014 Apr 1. Erratum in: Evid Based Ment Health. 2014 Aug;17(3):89.


Characteristics of networks of interventions: a description of a database of 186 published networks.

Nikolakopoulou A, Chaimani A, Veroniki AA, Vasiliadis HS, Schmid CH, Salanti G.

PLoS One. 2014 Jan 22;9(1):e86754. doi: 10.1371/journal.pone.0086754. eCollection 2014.


Activated microglia enhance neurogenesis via trypsinogen secretion.

Nikolakopoulou AM, Dutta R, Chen Z, Miller RH, Trapp BD.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8714-9. doi: 10.1073/pnas.1218856110. Epub 2013 May 6.


Interstitial nephritis and nephrogenic diabetes insipidus in a patient treated with pemetrexed.

Stavroulopoulos A, Nakopoulou L, Xydakis AM, Aresti V, Nikolakopoulou A, Klouvas G.

Ren Fail. 2010;32(8):1000-4. doi: 10.3109/0886022X.2010.501930.


Synaptic maturation of the Xenopus retinotectal system: effects of brain-derived neurotrophic factor on synapse ultrastructure.

Nikolakopoulou AM, Meynard MM, Marshak S, Cohen-Cory S.

J Comp Neurol. 2010 Apr 1;518(7):972-89. doi: 10.1002/cne.22258.


Netrin participates in the development of retinotectal synaptic connectivity by modulating axon arborization and synapse formation in the developing brain.

Manitt C, Nikolakopoulou AM, Almario DR, Nguyen SA, Cohen-Cory S.

J Neurosci. 2009 Sep 9;29(36):11065-77. doi: 10.1523/JNEUROSCI.0947-09.2009.


Combination of bisphosphonates and antiangiogenic factors induces osteonecrosis of the jaw more frequently than bisphosphonates alone.

Christodoulou C, Pervena A, Klouvas G, Galani E, Falagas ME, Tsakalos G, Visvikis A, Nikolakopoulou A, Acholos V, Karapanagiotidis G, Batziou E, Skarlos DV.

Oncology. 2009;76(3):209-11. doi: 10.1159/000201931. Epub 2009 Feb 12.


Communicating the diagnosis of multiple sclerosis: results of a survey among Greek neurologists.

Papathanasopoulos P, Messinis L, Lyros E, Nikolakopoulou A, Gourzoulidou E, Malefaki S.

J Neurol. 2008 Dec;255(12):1963-9. doi: 10.1007/s00415-008-0067-8. Epub 2008 Dec 20.


Response of malignant thymoma to erlotinib.

Christodoulou C, Murray S, Dahabreh J, Petraki K, Nikolakopoulou A, Mavri A, Skarlos D.

Ann Oncol. 2008 Jul;19(7):1361-2. doi: 10.1093/annonc/mdn388. Epub 2008 Jun 4. No abstract available.


Passive avoidance training is correlated with decreased cell proliferation in the chick hippocampus.

Nikolakopoulou AM, Dermon CR, Panagis L, Pavlidis M, Stewart MG.

Eur J Neurosci. 2006 Nov;24(9):2631-42.


Early post-hatching sex differences in cell proliferation and survival in the quail telencephalic ventricular zone and intermediate medial mesopallium.

Nikolakopoulou AM, Parpas A, Panagis L, Zikopoulos B, Dermon CR.

Brain Res Bull. 2006 Jun 30;70(2):107-16. Epub 2006 May 15.


Passive avoidance training decreases synapse density in the hippocampus of the domestic chick.

Nikolakopoulou AM, Davies HA, Stewart MG.

Eur J Neurosci. 2006 Feb;23(4):1054-62.


Disclosing the diagnosis of multiple sclerosis.

Papathanasopoulos PG, Nikolakopoulou A, Scolding NJ.

J Neurol. 2005 Nov;252(11):1307-9. Epub 2005 Nov 28.


BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo.

Hu B, Nikolakopoulou AM, Cohen-Cory S.

Development. 2005 Oct;132(19):4285-98. Epub 2005 Sep 1.


Fibrotic idiopathic interstitial pneumonia: the prognostic value of longitudinal functional trends.

Latsi PI, du Bois RM, Nicholson AG, Colby TV, Bisirtzoglou D, Nikolakopoulou A, Veeraraghavan S, Hansell DM, Wells AU.

Am J Respir Crit Care Med. 2003 Sep 1;168(5):531-7. Epub 2003 Jun 5.


Effect of exercise on motor evoked potentials elicited by transcranial magnetic stimulation in psychiatric patients.

Chroni E, Lekka NP, Tsoussis I, Nikolakopoulou A, Paschalis C, Beratis S.

J Clin Neurophysiol. 2002 Jun;19(3):240-4.


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