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Items: 11

1.

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.

Picaud S, Leonards K, Lambert JP, Dovey O, Wells C, Fedorov O, Monteiro O, Fujisawa T, Wang CY, Lingard H, Tallant C, Nikbin N, Guetzoyan L, Ingham R, Ley SV, Brennan P, Muller S, Samsonova A, Gingras AC, Schwaller J, Vassiliou G, Knapp S, Filippakopoulos P.

Sci Adv. 2016 Oct 12;2(10):e1600760. eCollection 2016 Oct.

2.

Continuous flow chemistry: a discovery tool for new chemical reactivity patterns.

Hartwig J, Metternich JB, Nikbin N, Kirschning A, Ley SV.

Org Biomol Chem. 2014 Jun 14;12(22):3611-5. doi: 10.1039/c4ob00662c. Epub 2014 Apr 25.

PMID:
24763674
3.

On the Brønsted acid-catalyzed homogeneous hydrolysis of furans.

Nikbin N, Caratzoulas S, Vlachos DG.

ChemSusChem. 2013 Nov;6(11):2066-8. doi: 10.1002/cssc.201300432. Epub 2013 Sep 4.

PMID:
24006230
4.

A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1.

Battilocchio C, Deadman BJ, Nikbin N, Kitching MO, Baxendale IR, Ley SV.

Chemistry. 2013 Jun 10;19(24):7917-30. doi: 10.1002/chem.201300696. Epub 2013 Apr 16.

PMID:
23592596
5.

A "catch-react-release" method for the flow synthesis of 2-aminopyrimidines and preparation of the Imatinib base.

Ingham RJ, Riva E, Nikbin N, Baxendale IR, Ley SV.

Org Lett. 2012 Aug 3;14(15):3920-3. doi: 10.1021/ol301673q. Epub 2012 Jul 19.

PMID:
22812401
6.

An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals.

Baumann M, Baxendale IR, Ley SV, Nikbin N.

Beilstein J Org Chem. 2011;7:442-95. doi: 10.3762/bjoc.7.57. Epub 2011 Apr 18.

7.

A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles.

Smith CJ, Nikbin N, Ley SV, Lange H, Baxendale IR.

Org Biomol Chem. 2011 Mar 21;9(6):1938-47. doi: 10.1039/c0ob00815j. Epub 2011 Jan 31.

PMID:
21283874
8.

Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent.

Smith CJ, Smith CD, Nikbin N, Ley SV, Baxendale IR.

Org Biomol Chem. 2011 Mar 21;9(6):1927-37. doi: 10.1039/c0ob00813c. Epub 2011 Jan 31.

PMID:
21283873
9.

The application of flow microreactors to the preparation of a family of casein kinase I inhibitors.

Venturoni F, Nikbin N, Ley SV, Baxendale IR.

Org Biomol Chem. 2010 Apr 21;8(8):1798-806. doi: 10.1039/b925327k.

PMID:
20449482
10.

Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions.

Baumann M, Baxendale IR, Ley SV, Nikbin N, Smith CD.

Org Biomol Chem. 2008 May 7;6(9):1587-93. doi: 10.1039/b801634h. Epub 2008 Mar 12.

PMID:
18421390
11.

A modular flow reactor for performing Curtius rearrangements as a continuous flow process.

Baumann M, Baxendale IR, Ley SV, Nikbin N, Smith CD, Tierney JP.

Org Biomol Chem. 2008 May 7;6(9):1577-86. doi: 10.1039/b801631n. Epub 2008 Mar 12.

PMID:
18421389

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