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Items: 1 to 50 of 388

1.

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

Dietrich DR, Aulock SV, Marquardt H, Blaauboer B, Dekant W, Kehrer J, Hengstler J, Collier A, Gori GB, Pelkonen O, Lang F, Nijkamp FP, Stemmer K, Li A, Savolainen K, Hayes AW, Gooderham N, Harvey A, Barile FA.

Toxicon. 2013 Dec 15;76:A1-A2. doi: 10.1016/j.toxicon.2013.10.020. Epub 2013 Oct 24. No abstract available.

PMID:
24512766
2.

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

Dietrich DR, von Aulock S, Marquardt H, Blaauboer B, Dekant W, Kehrer J, Hengstler J, Collier A, Gori GB, Pelkonen O, Lang F, Nijkamp FP, Stemmer K, Li A, Savolainen K, Hayes AW, Gooderham N, Harvey A, Barile FA.

Toxicon. 2013 Dec 15;76:A1-A2. No abstract available.

PMID:
24409469
3.

Open letter to the European Commission: scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science, and risk assessment principles.

Dietrich D, von Aulock S, Marquardt HW, Blaauboer BJ, Dekant W, Kehrer J, Hengstler JG, Collier AC, Gori GB, Pelkonen O, Lang F, Nijkamp FP, Stemmer K, Li A, Savolainen K, Hayes AW, Gooderham N, Harvey A.

Arch Toxicol. 2013 Sep;87(9):1739-41. doi: 10.1007/s00204-013-1117-2. Epub 2013 Aug 27. No abstract available.

PMID:
23979651
4.

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

Dietrich DR, von Aulock S, Marquardt H, Blaauboer B, Dekant W, Kehrer J, Hengstler J, Collier A, Batta Gori G, Pelkonen O, Lang F, Nijkamp FP, Stemmer K, Li A, Savolainen K, Wallace Hayes A, Gooderham N, Harvey A.

ALTEX. 2013;30(3):381-5. doi: 10.14573/altex.2013.3.381. No abstract available.

5.

Editorial.

Dietrich DR, von Aulock S, Marquardt H, Blaauboer B, Dekant W, Hengstler J, Collier A, Gori GB, Pelkonen O, Lang F, Nijkamp FP, Stemmer K, Li A, Savolainen K, Hayes AW, Gooderham N, Harvey A.

Regul Toxicol Pharmacol. 2013 Dec;67(3):317-20. doi: 10.1016/j.yrtph.2013.07.001. Epub 2013 Jul 9. No abstract available.

PMID:
23850959
6.

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

Dietrich DR, von Aulock S, Marquardt H, Blaauboer B, Dekant W, Kehrer J, Hengstler J, Collier A, Gori GB, Pelkonen OP, Lang F, Nijkamp FP, Stemmer K, Li A, Savolainen K, Hayes A, Gooderham N, Harvey A.

Toxicol In Vitro. 2013 Oct;27(7):2110-4. doi: 10.1016/j.tiv.2013.07.001. Epub 2013 Jul 9. No abstract available.

PMID:
23850741
7.

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

Dietrich DR, von Aulock S, Marquardt H, Blaauboer B, Dekant W, Kehrer J, Hengstler J, Collier A, Gori GB, Pelkonen O, Lang F, Nijkamp FP, Stemmer K, Li A, Savolainen K, Hayes AW, Gooderham N, Harvey A.

Food Chem Toxicol. 2013 Dec;62:A1-4. doi: 10.1016/j.fct.2013.07.005. Epub 2013 Jul 5. No abstract available.

PMID:
23835284
8.

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

Dietrich DR, Aulock Sv, Marquardt H, Blaauboer B, Dekant W, Kehrer J, Hengstler J, Collier A, Gori GB, Pelkonen O, Lang F, Barile FA, Nijkamp FP, Stemmer K, Li A, Savolainen K, Hayes AW, Gooderham N, Harvey A.

Chem Biol Interact. 2013 Sep 5;205(1):A1-5. doi: 10.1016/j.cbi.2013.07.001. Epub 2013 Jul 4. No abstract available.

PMID:
23832050
9.

Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation.

Thio M, Groot Kormelink T, Fischer MJ, Blokhuis BR, Nijkamp FP, Redegeld FA.

PLoS One. 2012;7(7):e40986. doi: 10.1371/journal.pone.0040986. Epub 2012 Jul 20.

10.

Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes.

van Eijl S, Mortaz E, Ferreira AF, Kuper F, Nijkamp FP, Folkerts G, Bloksma N.

Pulm Pharmacol Ther. 2011 Dec;24(6):682-9. doi: 10.1016/j.pupt.2011.07.001. Epub 2011 Jul 24.

PMID:
21820074
11.

A low vitamin A status increases the susceptibility to cigarette smoke-induced lung emphysema in C57BL/6J mice.

van Eijl S, Mortaz E, Versluis C, Nijkamp FP, Folkerts G, Bloksma N.

J Physiol Pharmacol. 2011 Apr;62(2):175-82.

12.

Respiratory sensitization: advances in assessing the risk of respiratory inflammation and irritation.

Vandebriel R, Callant Cransveld C, Crommelin D, Diamant Z, Glazenburg B, Joos G, Kuper F, Natsch A, Nijkamp F, Noteborn H, Pieters R, Roberts D, Roggen E, Rorije E, Seed M, Sewald K, van den Heuvel R, van Engelen J, Verstraelen S, van Loveren H.

Toxicol In Vitro. 2011 Oct;25(7):1251-8. doi: 10.1016/j.tiv.2011.04.027. Epub 2011 May 5. Review.

PMID:
21570460
13.

N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release.

Overbeek SA, Henricks PA, Srienc AI, Koelink PJ, de Kruijf P, Lim HD, Smit MJ, Zaman GJ, Garssen J, Nijkamp FP, Kraneveld AD, Folkerts G.

Eur J Pharmacol. 2011 Oct 15;668(3):428-34. doi: 10.1016/j.ejphar.2011.03.022. Epub 2011 Mar 31.

14.

A whey-based glutathione-enhancing diet decreases allergen-induced airway contraction in a guinea-pig model of asthma.

Kloek J, Mortaz E, Van Ark I, Bloksma N, Garssen J, Nijkamp FP, Folkerts G.

Br J Nutr. 2011 May;105(10):1465-70. doi: 10.1017/S0007114510005337. Epub 2011 Feb 8.

PMID:
21303576
15.

Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.

Braber S, Koelink PJ, Henricks PA, Jackson PL, Nijkamp FP, Garssen J, Kraneveld AD, Blalock JE, Folkerts G.

Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L255-65. doi: 10.1152/ajplung.00304.2010. Epub 2010 Nov 26.

16.

Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation.

Braber S, Henricks PA, Nijkamp FP, Kraneveld AD, Folkerts G.

Respir Res. 2010 Jul 22;11:99. doi: 10.1186/1465-9921-11-99.

17.

Ig-free light chains play a crucial role in murine mast cell-dependent colitis and are associated with human inflammatory bowel diseases.

Rijnierse A, Redegeld FA, Blokhuis BR, Van der Heijden MW, Te Velde AA, Pronk I, Hommes DW, Nijkamp FP, Koster AS, Kraneveld AD.

J Immunol. 2010 Jul 1;185(1):653-9. doi: 10.4049/jimmunol.0901129. Epub 2010 May 26.

18.

ATP and the pathogenesis of COPD.

Mortaz E, Folkerts G, Nijkamp FP, Henricks PA.

Eur J Pharmacol. 2010 Jul 25;638(1-3):1-4. doi: 10.1016/j.ejphar.2010.04.019. Epub 2010 Apr 24. Review.

PMID:
20423711
19.

Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs.

Kloek J, Mortaz E, van Ark I, Lilly CM, Nijkamp FP, Folkerts G.

J Physiol Pharmacol. 2010 Feb;61(1):67-72.

20.

New insights on the possible role of mast cells in aspirin-induced asthma.

Mortaz E, Engels F, Nijkamp FP, Redegeld FA.

Curr Mol Pharmacol. 2009 Jun;2(2):182-9. Review.

PMID:
20021457
21.

IL-8 production by macrophages is synergistically enhanced when cigarette smoke is combined with TNF-alpha.

Sarir H, Mortaz E, Janse WT, Givi ME, Nijkamp FP, Folkerts G.

Biochem Pharmacol. 2010 Mar 1;79(5):698-705. doi: 10.1016/j.bcp.2009.10.001. Epub 2009 Oct 27.

PMID:
19874800
22.

Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor.

Mortaz E, Adcock IM, Ito K, Kraneveld AD, Nijkamp FP, Folkerts G.

Eur Respir J. 2010 Nov;36(5):1143-54. doi: 10.1183/09031936.00062209. Epub 2009 Oct 19.

23.

Oral treatment with probiotics reduces allergic symptoms in ovalbumin-sensitized mice: a bacterial strain comparative study.

Hougee S, Vriesema AJ, Wijering SC, Knippels LM, Folkerts G, Nijkamp FP, Knol J, Garssen J.

Int Arch Allergy Immunol. 2010;151(2):107-17. doi: 10.1159/000236000. Epub 2009 Sep 15.

24.

ATP in the pathogenesis of lung emphysema.

Mortaz E, Braber S, Nazary M, Givi ME, Nijkamp FP, Folkerts G.

Eur J Pharmacol. 2009 Oct 1;619(1-3):92-6. doi: 10.1016/j.ejphar.2009.07.022. Epub 2009 Aug 3.

PMID:
19654006
25.

Acute allergic skin response as a new tool to evaluate the allergenicity of whey hydrolysates in a mouse model of orally induced cow's milk allergy.

van Esch BC, Schouten B, Hofman GA, van Baalen T, Nijkamp FP, Knippels LM, Willemsen LE, Garssen J.

Pediatr Allergy Immunol. 2010 Jun;21(4 Pt 2):e780-6. doi: 10.1111/j.1399-3038.2009.00924.x. Epub 2009 Jun 26.

PMID:
19563464
26.

Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation.

Mortaz E, Lazar Z, Koenderman L, Kraneveld AD, Nijkamp FP, Folkerts G.

Respir Res. 2009 Jun 10;10:47. doi: 10.1186/1465-9921-10-47.

27.

Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages.

Sarir H, Mortaz E, Karimi K, Kraneveld AD, Rahman I, Caldenhoven E, Nijkamp FP, Folkerts G.

J Inflamm (Lond). 2009 May 1;6:12. doi: 10.1186/1476-9255-6-12.

28.

Effect of cigarette smoke extract on dendritic cells and their impact on T-cell proliferation.

Mortaz E, Kraneveld AD, Smit JJ, Kool M, Lambrecht BN, Kunkel SL, Lukacs NW, Nijkamp FP, Folkerts G.

PLoS One. 2009;4(3):e4946. doi: 10.1371/journal.pone.0004946. Epub 2009 Mar 18.

29.

Cigarette smoke suppresses in vitro allergic activation of mouse mast cells.

Mortaz E, Folkerts G, Engels F, Nijkamp FP, Redegeld FA.

Clin Exp Allergy. 2009 May;39(5):679-87. doi: 10.1111/j.1365-2222.2009.03209.x. Epub 2009 Mar 2.

PMID:
19260869
30.

Immunoglobulin-free light chains mediate antigen-specific responses of murine dorsal root ganglion neurons.

Rijnierse A, Kroese AB, Redegeld FA, Blokhuis BR, van der Heijden MW, Koster AS, Timmermans JP, Nijkamp FP, Kraneveld AD.

J Neuroimmunol. 2009 Mar 31;208(1-2):80-6. doi: 10.1016/j.jneuroim.2009.01.008. Epub 2009 Feb 15.

PMID:
19232443
31.

Atopic and non-atopic allergic disorders: current insights into the possible involvement of free immunoglobulin light chains.

Groot Kormelink T, Thio M, Blokhuis BR, Nijkamp FP, Redegeld FA.

Clin Exp Allergy. 2009 Jan;39(1):33-42. doi: 10.1111/j.1365-2222.2008.03135.x. Epub 2008 Nov 17.

PMID:
19040467
32.

Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke.

Mortaz E, Rad MV, Johnson M, Raats D, Nijkamp FP, Folkerts G.

J Mol Med (Berl). 2008 Sep;86(9):1045-56. doi: 10.1007/s00109-008-0360-0. Epub 2008 Jul 4.

33.

Induction of lung emphysema is prevented by L-arginine-threonine-arginine.

van Houwelingen AH, Weathington NM, Verweij V, Blalock JE, Nijkamp FP, Folkerts G.

FASEB J. 2008 Sep;22(9):3403-8. doi: 10.1096/fj.07-096230. Epub 2008 Jun 12.

34.

The guinea pig as an animal model for asthma.

Ricciardolo FL, Nijkamp F, De Rose V, Folkerts G.

Curr Drug Targets. 2008 Jun;9(6):452-65. Review.

PMID:
18537584
35.

Neuro-immune interactions in inflammatory bowel disease and irritable bowel syndrome: future therapeutic targets.

Kraneveld AD, Rijnierse A, Nijkamp FP, Garssen J.

Eur J Pharmacol. 2008 May 13;585(2-3):361-74. doi: 10.1016/j.ejphar.2008.02.095. Epub 2008 Mar 18. Review.

PMID:
18417115
36.

Mechanisms of allergy and asthma.

Nauta AJ, Engels F, Knippels LM, Garssen J, Nijkamp FP, Redegeld FA.

Eur J Pharmacol. 2008 May 13;585(2-3):354-60. doi: 10.1016/j.ejphar.2008.02.094. Epub 2008 Mar 18. Review.

PMID:
18410921
37.

Cells, mediators and Toll-like receptors in COPD.

Sarir H, Henricks PA, van Houwelingen AH, Nijkamp FP, Folkerts G.

Eur J Pharmacol. 2008 May 13;585(2-3):346-53. doi: 10.1016/j.ejphar.2008.03.009. Epub 2008 Mar 18. Review.

PMID:
18410916
38.

New endogenous CXC chemokine ligands as potential targets in lung emphysema.

Folkerts G, Kraneveld AD, Nijkamp FP.

Trends Pharmacol Sci. 2008 Apr;29(4):181-5. doi: 10.1016/j.tips.2008.01.005. Epub 2008 Mar 18. Review.

PMID:
18353448
39.

Free immunoglobulin light chains: a novel target in the therapy of inflammatory diseases.

Thio M, Blokhuis BR, Nijkamp FP, Redegeld FA.

Trends Pharmacol Sci. 2008 Apr;29(4):170-4. doi: 10.1016/j.tips.2008.01.004. Epub 2008 Mar 18. Review.

PMID:
18353446
40.

Cigarette smoke stimulates the production of chemokines in mast cells.

Mortaz E, Redegeld FA, Sarir H, Karimi K, Raats D, Nijkamp FP, Folkerts G.

J Leukoc Biol. 2008 Mar;83(3):575-80. Epub 2007 Dec 21.

PMID:
18156185
41.

Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice.

Blasi F, Aliberti S, Allegra L, Piatti G, Tarsia P, Ossewaarde JM, Verweij V, Nijkamp FP, Folkerts G.

Respir Res. 2007 Nov 19;8:83.

42.

Bacille-Calmette-Guerin vaccination and the development of allergic disease in children: a randomized, prospective, single-blind study.

Steenhuis TJ, van Aalderen WM, Bloksma N, Nijkamp FP, van der Laag J, van Loveren H, Rijkers GT, Kuis W, Hoekstra MO.

Clin Exp Allergy. 2008 Jan;38(1):79-85. Epub 2007 Oct 23.

PMID:
17956585
43.

Dietary supplementation with specific oligosaccharide mixtures decreases parameters of allergic asthma in mice.

Vos AP, van Esch BC, Stahl B, M'Rabet L, Folkerts G, Nijkamp FP, Garssen J.

Int Immunopharmacol. 2007 Dec 5;7(12):1582-7. Epub 2007 Aug 17.

PMID:
17920536
44.

Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome.

Rijnierse A, Nijkamp FP, Kraneveld AD.

Pharmacol Ther. 2007 Nov;116(2):207-35. Epub 2007 Jul 18. Review.

PMID:
17719089
45.

Combination of fluticasone propionate and salmeterol potentiates the suppression of cigarette smoke-induced IL-8 production by macrophages.

Sarir H, Mortaz E, Karimi K, Johnson M, Nijkamp FP, Folkerts G.

Eur J Pharmacol. 2007 Sep 24;571(1):55-61. Epub 2007 Jun 5.

PMID:
17631879
46.

Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid.

Mortaz E, Redegeld FA, Dunsmore K, Odoms K, Wong HR, Nijkamp FP, Engels F.

Eur J Pharmacol. 2007 Apr 30;561(1-3):214-9. Epub 2007 Jan 20.

PMID:
17306251
47.

Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in mice.

van Houwelingen AH, Kaczynska K, Kraneveld AD, Kool M, Nijkamp FP, Redegeld FA.

Clin Exp Allergy. 2007 Feb;37(2):270-5.

PMID:
17250700
48.

Nitric oxide in asthma therapy.

Folkerts G, Nijkamp FP.

Curr Pharm Des. 2006;12(25):3221-32. Review.

PMID:
17020530
49.

Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA.

de Vries A, Engels F, Henricks PA, Leusink-Muis T, McGregor GP, Braun A, Groneberg DA, Dessing MC, Nijkamp FP, Fischer A.

Clin Exp Allergy. 2006 Sep;36(9):1192-200.

PMID:
16961720
50.

Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice.

Rijnierse A, van Zijl KM, Koster AS, Nijkamp FP, Kraneveld AD.

Eur J Pharmacol. 2006 Oct 24;548(1-3):150-7. Epub 2006 Jul 25.

PMID:
16949572

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