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Items: 1 to 50 of 568

1.

Clinical outcomes of 20 Japanese patients with insulinoma treated with diazoxide.

Niitsu Y, Minami I, Izumiyama H, Hashimoto K, Yoshimoto T, Satou F, Tsujino M, Ota K, Kudo A, Tanabe M, Yamada T, Ogawa Y.

Endocr J. 2019 Feb 28;66(2):149-155. doi: 10.1507/endocrj.EJ18-0353. Epub 2018 Nov 30.

2.

Staphylococcus aureus from atopic dermatitis skin accumulates in the lysosomes of keratinocytes with induction of IL-1α secretion via TLR9.

Moriwaki M, Iwamoto K, Niitsu Y, Matsushima A, Yanase Y, Hisatsune J, Sugai M, Hide M.

Allergy. 2019 Mar;74(3):560-571. doi: 10.1111/all.13622. Epub 2018 Nov 12.

PMID:
30269350
3.

[Complications and Proposed Preventive Measure of Holumium Laser Enucleation of the Prostate during the Initial Phase at Our Hospital].

Takeuchi Y, Sekido N, Sawada Y, Hashimoto H, Miyazaki K, Watanabe K, Watanabe S, Kinno K, Niitsu Y, Endo F.

Hinyokika Kiyo. 2018 May;64(5):207-212. doi: 10.14989/ActaUrolJap_64_5_207. Japanese.

4.

Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease.

Yamakawa T, Ohigashi H, Hashimoto D, Hayase E, Takahashi S, Miyazaki M, Minomi K, Onozawa M, Niitsu Y, Teshima T.

Blood. 2018 Mar 29;131(13):1476-1485. doi: 10.1182/blood-2017-04-779934. Epub 2018 Jan 23.

5.

Treatment of pulmonary fibrosis with siRNA against a collagen-specific chaperone HSP47 in vitamin A-coupled liposomes.

Otsuka M, Shiratori M, Chiba H, Kuronuma K, Sato Y, Niitsu Y, Takahashi H.

Exp Lung Res. 2017 Aug - Sep;43(6-7):271-282. doi: 10.1080/01902148.2017.1354946. Epub 2017 Oct 16.

PMID:
29035148
6.

Novel splice site mutation in GATA3 in a patient with HDR syndrome.

Matsuo K, Kobayashi A, Tanahashi Y, Maruyama S, Niitsu Y, Katsuta H, Furuya A, Suzuki S, Kawamura M, Azuma H.

Clin Pediatr Endocrinol. 2017;26(4):271-273. doi: 10.1297/cpe.26.271. Epub 2017 Sep 28. No abstract available.

7.

Staphylococcus aureus from atopic dermatitis skin alters cytokine production triggered by monocyte-derived Langerhans cell.

Iwamoto K, Moriwaki M, Niitsu Y, Saino M, Takahagi S, Hisatsune J, Sugai M, Hide M.

J Dermatol Sci. 2017 Dec;88(3):271-279. doi: 10.1016/j.jdermsci.2017.08.001. Epub 2017 Aug 5.

PMID:
28822698
8.

Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy.

Ota S, Nishimura M, Murakami Y, Birukawa NK, Yoneda A, Nishita H, Fujita R, Sato Y, Minomi K, Kajiwara K, Miyazaki M, Uchiumi M, Mikuni S, Tamura Y, Mizuguchi T, Imamura M, Meguro M, Kimura Y, Hirata K, Niitsu Y.

PLoS One. 2016 Dec 9;11(12):e0165747. doi: 10.1371/journal.pone.0165747. eCollection 2016.

9.

Panitumumab in combination with irinotecan plus S-1 (IRIS) as second-line therapy for metastatic colorectal cancer.

Takaoka T, Kimura T, Shimoyama R, Kawamoto S, Sakamoto K, Goda F, Miyamoto H, Negoro Y, Tsuji A, Yoshizaki K, Goji T, Kitamura S, Yano H, Okamoto K, Kimura M, Okahisa T, Muguruma N, Niitsu Y, Takayama T.

Cancer Chemother Pharmacol. 2016 Aug;78(2):397-403. doi: 10.1007/s00280-016-3096-5. Epub 2016 Jun 24.

PMID:
27342247
10.

Vitamin A and insulin are required for the maintenance of hepatic stellate cell quiescence.

Yoneda A, Sakai-Sawada K, Niitsu Y, Tamura Y.

Exp Cell Res. 2016 Feb 1;341(1):8-17. doi: 10.1016/j.yexcr.2016.01.012. Epub 2016 Jan 23.

PMID:
26812497
11.

Efficacy and safety of sitagliptin for the treatment of diabetes mellitus complicated by chronic liver injury.

Asakawa M, Mitsui H, Akihisa M, Sekine T, Niitsu Y, Kobayashi A, Miyake A, Hashimoto N, Kawamura M, Ogawa Y.

Springerplus. 2015 Jul 15;4:346. doi: 10.1186/s40064-015-1135-z. eCollection 2015.

12.

A Case of Rathke's Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus.

Asakawa M, Chin R, Niitsu Y, Sekine T, Niwa A, Miyake A, Inoshita N, Kawamura M, Ogawa Y, Hirata Y.

Case Rep Endocrinol. 2014;2014:693294. doi: 10.1155/2014/693294. Epub 2014 Nov 6.

13.

Activated hepatic stellate cells are dependent on self-collagen, cleaved by membrane type 1 matrix metalloproteinase for their growth.

Birukawa NK, Murase K, Sato Y, Kosaka A, Yoneda A, Nishita H, Fujita R, Nishimura M, Ninomiya T, Kajiwara K, Miyazaki M, Nakashima Y, Ota S, Murakami Y, Tanaka Y, Minomi K, Tamura Y, Niitsu Y.

J Biol Chem. 2014 Jul 18;289(29):20209-21. doi: 10.1074/jbc.M113.544494. Epub 2014 May 27.

14.

Ministrokes in channelrhodopsin-2 transgenic mice reveal widespread deficits in motor output despite maintenance of cortical neuronal excitability.

Anenberg E, Arstikaitis P, Niitsu Y, Harrison TC, Boyd JD, Hilton BJ, Tetzlaff W, Murphy TH.

J Neurosci. 2014 Jan 22;34(4):1094-104. doi: 10.1523/JNEUROSCI.1442-13.2014.

15.

Treatment of pancreatic fibrosis with siRNA against a collagen-specific chaperone in vitamin A-coupled liposomes.

Ishiwatari H, Sato Y, Murase K, Yoneda A, Fujita R, Nishita H, Birukawa NK, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Ota S, Kimura Y, Hirata K, Kato J, Niitsu Y.

Gut. 2013 Sep;62(9):1328-39. doi: 10.1136/gutjnl-2011-301746. Epub 2012 Nov 20.

PMID:
23172890
16.

Efficacy and safety of micafungin as an empirical antifungal therapy for suspected fungal infection in neutropenic patients with hematological disorders.

Yoshida M, Tamura K, Imamura M, Niitsu Y, Sasaki T, Urabe A, Ohyashiki K, Naoe T, Kanamaru A, Tanimoto M, Masaoka T.

Ann Hematol. 2012 Mar;91(3):449-57. doi: 10.1007/s00277-011-1316-y. Epub 2011 Sep 6.

PMID:
21894476
17.

Selective blockade of P2Y12 receptors by prasugrel inhibits myocardial infarction induced by thrombotic coronary artery occlusion in rats.

Sugidachi A, Yamaguchi S, Jakubowski JA, Ohno K, Tomizawa A, Hashimoto M, Niitsu Y.

J Cardiovasc Pharmacol. 2011 Sep;58(3):329-34. doi: 10.1097/FJC.0b013e3182244a6f.

PMID:
21697729
18.

Chemoenzymatic synthesis of (2R,3R,4R)-dehydroxymethylepoxyquinomicin (DHMEQ), a new activator of antioxidant transcription factor Nrf2.

Niitsu Y, Hakamata M, Goto Y, Higashi T, Shoji M, Sugai T, Umezawa K.

Org Biomol Chem. 2011 Jun 21;9(12):4635-41. doi: 10.1039/c1ob05205e. Epub 2011 May 3.

PMID:
21541373
19.

Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke.

Honmou O, Houkin K, Matsunaga T, Niitsu Y, Ishiai S, Onodera R, Waxman SG, Kocsis JD.

Brain. 2011 Jun;134(Pt 6):1790-807. doi: 10.1093/brain/awr063. Epub 2011 Apr 14.

20.

Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps.

Takayama T, Nagashima H, Maeda M, Nojiri S, Hirayama M, Nakano Y, Takahashi Y, Sato Y, Sekikawa H, Mori M, Sonoda T, Kimura T, Kato J, Niitsu Y.

Clin Cancer Res. 2011 Jun 1;17(11):3803-11. doi: 10.1158/1078-0432.CCR-10-2395. Epub 2011 Mar 8.

21.

Pure red cell aplasia associated with Good's syndrome accompanied by decreased stem cell factor production in the bone marrow.

Kuribayashi K, Fujimi A, Kobune M, Takimoto R, Kikuchi S, Iyama S, Kato J, Niitsu Y, Watanabe N.

Intern Med. 2010;49(5):377-82. Epub 2010 Mar 1.

22.

Phase II study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer.

Sato Y, Takayama T, Sagawa T, Takahashi Y, Ohnuma H, Okubo S, Shintani N, Tanaka S, Kida M, Sato Y, Ohta H, Miyanishi K, Sato T, Takimoto R, Kobune M, Yamaguchi K, Hirata K, Niitsu Y, Kato J.

Cancer Chemother Pharmacol. 2010 Sep;66(4):721-8. doi: 10.1007/s00280-009-1215-2. Epub 2009 Dec 30.

PMID:
20041328
23.

Apoptotic death of hematopoietic tumor cells through potentiated and sustained adhesion to fibronectin via VLA-4.

Saito Y, Owaki T, Matsunaga T, Saze M, Miura S, Maeda M, Eguchi M, Tanaka R, Taira J, Kodama H, Goto S, Niitsu Y, Terada H, Fukai F.

J Biol Chem. 2010 Mar 5;285(10):7006-15. doi: 10.1074/jbc.M109.027581. Epub 2009 Dec 10.

24.

Interleukin-2 gene transfer potentiates the alpha-galactosylceramide-stimulated antitumor effect by the induction of TRAIL in NKT and NK cells in mouse models of subcutaneous and metastatic carcinoma.

Nishihori Y, Kato K, Tanaka M, Okamoto T, Hagiwara S, Araki N, Kogawa K, Kuribayashi K, Nakamura K, Niitsu Y.

Cancer Biol Ther. 2009 Sep;8(18):1763-70.

PMID:
19901518
25.

Suppressive effect of sulindac on branch duct-intraductal papillary mucinous neoplasms.

Hayashi T, Ishiwatari H, Ihara H, Kawano Y, Takada K, Miyanishi K, Kobune M, Takimoto R, Sonoda T, Takayama T, Kato J, Niitsu Y.

J Gastroenterol. 2009;44(9):964-75. doi: 10.1007/s00535-009-0089-8. Epub 2009 Jun 18.

PMID:
19536452
26.

Effects of prasugrel, a novel P2Y(12) inhibitor, in rat models of cerebral and peripheral artery occlusive diseases.

Ogawa T, Hashimoto M, Niitsu Y, Jakubowski JA, Tani Y, Otsuguro K, Asai F, Sugidachi A.

Eur J Pharmacol. 2009 Jun 10;612(1-3):29-34. doi: 10.1016/j.ejphar.2009.03.073. Epub 2009 Apr 6.

PMID:
19356727
27.

Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells.

Kobune M, Takimoto R, Murase K, Iyama S, Sato T, Kikuchi S, Kawano Y, Miyanishi K, Sato Y, Niitsu Y, Kato J.

Cancer Sci. 2009 May;100(5):948-55. doi: 10.1111/j.1349-7006.2009.01111.x. Epub 2009 Feb 24.

28.

Discovery of R-142086 as a factor Xa (FXa) inhibitor: syntheses and structure-activity relationships of cinnamyl derivatives.

Noguchi T, Tanaka N, Nishimata T, Goto R, Hayakawa M, Sugidachi A, Ogawa T, Niitsu Y, Asai F, Ishizuka T, Fujimoto K.

Chem Pharm Bull (Tokyo). 2009 Jan;57(1):22-33.

29.

Successful treatment for gastro-intestinal bleeding of Osler-Weber-Rendu disease by argon plasma coagulation using double-balloon enteroscopy.

Sato Y, Takayama T, Takahari D, Sagawa T, Sato T, Abe S, Kogawa T, Nikaido T, Miyanishi K, Takahashi S, Kato J, Niitsu Y.

Endoscopy. 2008 Sep;40 Suppl 2:E228-9. doi: 10.1055/s-2007-966562. Epub 2008 Nov 7. No abstract available.

PMID:
18991211
30.

[Effective CDDP arterial infusion with DSM for liver metastasis of malignant melanoma complicating DIC due to intratumoral hemorrhage--a case report].

Takada K, Kato J, Kawano Y, Takahashi S, Hayashi T, Ishiwatari H, Miyanishi K, Takimoto R, Kobune M, Sagawa T, Sato T, Sato Y, Yamashita T, Natori H, Niitsu Y.

Gan To Kagaku Ryoho. 2008 Oct;35(10):1803-5. Japanese.

PMID:
18931594
31.

[Cyclic thrombocytopenia complicated with Sjögren syndrome and the mechanism of periodic platelet count fluctuation].

Yamauchi N, Muramatsu H, Inomata H, Numata T, Nozawa E, Nishino M, Koyama R, Ihara K, Nishisato T, Hirayama M, Katsuki S, Matsunaga T, Niitsu Y.

Rinsho Ketsueki. 2008 Aug;49(8):658-63. Japanese.

PMID:
18800616
32.

[A case of hepatosplenic gammadelta T-cell lymphoma associated hemophagocytic syndrome].

Iyama S, Matsunaga T, Sato T, Sato Y, Sagawa T, Murase K, Kida M, Kobune M, Takimoto R, Kato J, Niitsu Y.

Gan To Kagaku Ryoho. 2008 Sep;35(9):1623-7. Japanese.

PMID:
18799926
33.

Treatment of hepatocellular carcinoma by AdAFPep/rep, AdAFPep/p53, and 5-fluorouracil in mice.

Sagawa T, Yamada Y, Takahashi M, Sato Y, Kobune M, Takimoto R, Fukaura J, Iyama S, Sato T, Miyanishi K, Matsunaga T, Takayama T, Kato J, Sasaki K, Hamada H, Niitsu Y.

Hepatology. 2008 Sep;48(3):828-40. doi: 10.1002/hep.22420.

PMID:
18756484
34.

Japanese epidemiological survey with consensus statement on Japanese guidelines for treatment of iron overload in bone marrow failure syndromes.

Suzuki T, Tomonaga M, Miyazaki Y, Nakao S, Ohyashiki K, Matsumura I, Kohgo Y, Niitsu Y, Kojima S, Ozawa K.

Int J Hematol. 2008 Jul;88(1):30-35. doi: 10.1007/s12185-008-0119-y. Epub 2008 Jun 27. Review.

35.

Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptor-interacting protein and inhibition of lysosomal cathepsin.

Sato T, Machida T, Takahashi S, Murase K, Kawano Y, Hayashi T, Iyama S, Takada K, Kuribayashi K, Sato Y, Kobune M, Takimoto R, Matsunaga T, Kato J, Niitsu Y.

J Immunol. 2008 Jul 1;181(1):197-207.

36.

Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells.

Kobune M, Kawano Y, Takahashi S, Takada K, Murase K, Iyama S, Sato T, Takimoto R, Niitsu Y, Kato J.

Exp Hematol. 2008 Sep;36(9):1121-31. doi: 10.1016/j.exphem.2008.04.007. Epub 2008 Jun 17.

PMID:
18562079
37.

Successful treatment of autoimmune pancreatitis complicated with autoimmune thrombocytopenia and interstitial pneumonia by prednisolone.

Murase K, Matsunaga T, Hayashi T, Ishiwatari H, Araki N, Iyama S, Sato T, Kobune M, Takimoto R, Miyanishi K, Miyazaki T, Ikeda H, Kato J, Niitsu Y.

Intern Med. 2008;47(11):1033-8. Epub 2008 Jun 2.

38.

[Undifferentiated pleomorphic sarcoma detected in the descending colon: report of a case].

Hagiwara S, Hirayama M, Takahashi T, Meguro T, Morita T, Horita S, Niitsu Y.

Nihon Shokakibyo Gakkai Zasshi. 2008 May;105(5):692-8. Review. Japanese.

PMID:
18460858
39.

Successful treatment of chronic myeloproliferative disease-unclassifiable (CMPD-U) with no chromosomal abnormalities by imatinib mesylate.

Iyama S, Matsunaga T, Sato T, Murase K, Araki N, Takimoto R, Kobune M, Sagawa T, Takayama T, Niitsu Y.

Intern Med. 2008;47(8):791-4. Epub 2008 Apr 16.

40.

Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone.

Sato Y, Murase K, Kato J, Kobune M, Sato T, Kawano Y, Takimoto R, Takada K, Miyanishi K, Matsunaga T, Takayama T, Niitsu Y.

Nat Biotechnol. 2008 Apr;26(4):431-42. doi: 10.1038/nbt1396. Epub 2008 Mar 30.

PMID:
18376398
41.

A Phase I trial of arterial infusion chemotherapy with gemcitabine and 5-fluorouracil for unresectable advanced pancreatic cancer after vascular supply distribution via superselective embolization.

Miyanishi K, Ishiwatari H, Hayashi T, Takahashi M, Kawano Y, Takada K, Ihara H, Okuda T, Takanashi K, Takahashi S, Sato Y, Matsunaga T, Homma H, Kato J, Niitsu Y.

Jpn J Clin Oncol. 2008 Apr;38(4):268-74. doi: 10.1093/jjco/hyn015. Epub 2008 Mar 28.

PMID:
18375446
42.

Ex vivo large-scale generation of human red blood cells from cord blood CD34+ cells by co-culturing with macrophages.

Fujimi A, Matsunaga T, Kobune M, Kawano Y, Nagaya T, Tanaka I, Iyama S, Hayashi T, Sato T, Miyanishi K, Sagawa T, Sato Y, Takimoto R, Takayama T, Kato J, Gasa S, Sakai H, Tsuchida E, Ikebuchi K, Hamada H, Niitsu Y.

Int J Hematol. 2008 May;87(4):339-350. doi: 10.1007/s12185-008-0062-y.

PMID:
18369691
43.

[An advanced metastatic breast cancer patient successfully treated with combination therapy including docetaxel, doxorubicin and cyclophosphamide (TAC) as salvage therapy].

Sato Y, Takayama T, Sagawa T, Sato T, Okamoto K, Takahashi S, Abe S, Iyama S, Murase K, Kato J, Niitsu Y.

Gan To Kagaku Ryoho. 2008 Mar;35(3):471-3. Japanese.

PMID:
18347397
44.

[Anemia in patients with cancer].

Kobune M, Kato J, Niitsu Y.

Nihon Rinsho. 2008 Mar;66(3):524-9. Review. Japanese.

PMID:
18330028
45.

Case report of a focal nodular hyperplasia-like nodule present in cirrhotic liver.

Takahashi S, Miyanishi K, Takada K, Kawano Y, Sagawa T, Sato Y, Takimoto R, Takayama T, Kato J, Omatsu M, Hasegawa T, Kojiro M, Niitsu Y.

Hepatol Res. 2008 May;38(5):521-8. doi: 10.1111/j.1872-034X.2007.00294.x. Epub 2008 Jan 15.

PMID:
18201183
46.

Aberrant crypt foci as precursors of the dysplasia-carcinoma sequence in patients with ulcerative colitis.

Kukitsu T, Takayama T, Miyanishi K, Nobuoka A, Katsuki S, Sato Y, Takimoto R, Matsunaga T, Kato J, Sonoda T, Sakamaki S, Niitsu Y.

Clin Cancer Res. 2008 Jan 1;14(1):48-54. doi: 10.1158/1078-0432.CCR-07-1835.

47.

Repeat oral dosing of prasugrel, a novel P2Y12 receptor inhibitor, results in cumulative and potent antiplatelet and antithrombotic activity in several animal species.

Niitsu Y, Sugidachi A, Ogawa T, Jakubowski JA, Hashimoto M, Isobe T, Otsuguro K, Asai F.

Eur J Pharmacol. 2008 Jan 28;579(1-3):276-82. Epub 2007 Oct 11.

PMID:
17996866
48.

Combination therapy of an anticancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion-mediated drug resistance of acute myelogenous leukemia.

Matsunaga T, Fukai F, Miura S, Nakane Y, Owaki T, Kodama H, Tanaka M, Nagaya T, Takimoto R, Takayama T, Niitsu Y.

Leukemia. 2008 Feb;22(2):353-60. Epub 2007 Nov 1.

PMID:
17972943
49.

Adenoviral vector-mediated transfer of the Indian hedgehog gene modulates lymphomyelopoiesis in vivo.

Kobune M, Kato J, Kawano Y, Sasaki K, Uchida H, Takada K, Takahashi S, Takimoto R, Niitsu Y.

Stem Cells. 2008 Feb;26(2):534-42. Epub 2007 Oct 25.

50.

Long-term phlebotomy with low-iron diet therapy lowers risk of development of hepatocellular carcinoma from chronic hepatitis C.

Kato J, Miyanishi K, Kobune M, Nakamura T, Takada K, Takimoto R, Kawano Y, Takahashi S, Takahashi M, Sato Y, Takayama T, Niitsu Y.

J Gastroenterol. 2007 Oct;42(10):830-6. Epub 2007 Oct 15.

PMID:
17940836

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