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Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry.

Johno H, Yoshimura K, Mori Y, Kimura T, Niimi M, Yamada M, Tanigawa T, Fan J, Takeda S.

Metabolomics. 2018 Feb 27;14(4):38. doi: 10.1007/s11306-018-1334-z.


Graft Protective Effect of HMG-CoA Reductase Inhibitor Pravastatin in Murine Cardiac Allograft Transplantation.

Yin E, Hara M, Uchiyama M, Niimi M.

Transplant Proc. 2018 Nov;50(9):2804-2806. doi: 10.1016/j.transproceed.2018.05.029. Epub 2018 Jun 6.


More Hippocampal Weight and Cells in Cardiac Allograft Transplanted Mice.

Yin E, Uchiyama M, Jin X, Kawai K, Takao M, Niimi M.

Transplant Proc. 2018 Nov;50(9):2798-2803. doi: 10.1016/j.transproceed.2018.03.107. Epub 2018 Mar 21.


Administration of Thrombomodulin (CD141) Could Improve Cardiac Allograft Survival in Mice.

Yin E, Matsuyama S, Uchiyama M, Kawai K, Hara M, Imazuru T, Kono M, Niimi M.

Transplant Proc. 2018 Nov;50(9):2794-2797. doi: 10.1016/j.transproceed.2018.02.204. Epub 2018 Mar 19.


Seven Japanese Herbals Prolonged Cardiac Allograft Survival.

Yin E, Jin X, Uchiyama M, Zhang Q, Yanagisawa T, Inoue A, Guo Y, Hara M, Matsuyama S, Imazuru T, Kawamura M, Niimi M.

Transplant Proc. 2018 Nov;50(9):2789-2793. doi: 10.1016/j.transproceed.2018.04.015. Epub 2018 Apr 12.


FK506 Resistance of Saccharomyces cerevisiae Pdr5 and Candida albicans Cdr1 Involves Mutations in the Transmembrane Domains and Extracellular Loops.

Tanabe K, Bonus M, Tomiyama S, Miyoshi K, Nagi M, Niimi K, Chindamporn A, Gohlke H, Schmitt L, Cannon RD, Niimi M, Lamping E.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01146-18. doi: 10.1128/AAC.01146-18. Print 2019 Jan.


Treatment of atherosclerosis by traditional Chinese medicine: Questions and quandaries.

Wang C, Niimi M, Watanabe T, Wang Y, Liang J, Fan J.

Atherosclerosis. 2018 Oct;277:136-144. doi: 10.1016/j.atherosclerosis.2018.08.039. Epub 2018 Aug 30. Review.


The Effect of Repeated Botulinum Toxin A Therapy Combined with Intensive Rehabilitation on Lower Limb Spasticity in Post-Stroke Patients.

Hara T, Abo M, Hara H, Sasaki N, Yamada N, Niimi M, Shimamoto Y.

Toxins (Basel). 2018 Aug 31;10(9). pii: E349. doi: 10.3390/toxins10090349.


Administration of donor splenocytes via the respiratory tract generates CD8α+ regulatory dendritic cells and induces hyporesponsiveness to fully allogeneic cardiac grafts.

Iwami D, Aramaki O, Shinohara N, Niimi M, Shirasugi N.

Transpl Immunol. 2018 Oct;50:60-67. doi: 10.1016/j.trim.2018.07.001. Epub 2018 Jul 7.


Sleep during low-frequency repetitive transcranial magnetic stimulation is associated with functional improvement in upper limb hemiparesis after stroke.

Niimi M, Sasaki N, Kimura C, Hara T, Yamada N, Abo M.

Acta Neurol Belg. 2019 Jun;119(2):233-238. doi: 10.1007/s13760-018-0957-1. Epub 2018 Jun 7.


Graft protective effect and induction of CD4+Foxp3+ cell by Thrombomodulin on allograft arteriosclerosis in mice.

Yin E, Matsuyama S, Uchiyama M, Kawai K, Niimi M.

J Cardiothorac Surg. 2018 May 21;13(1):48. doi: 10.1186/s13019-018-0731-8.


Rikkunshito (TJ-43) Improved Reduction of Food Intake in a Murine Cardiac Transplantation Model.

Yin E, Uchiyama M, Niimi M.

Transplant Proc. 2018 Jan - Feb;50(1):283-292. doi: 10.1016/j.transproceed.2017.12.022.


Induction of Regulatory CD4+ Cells and Prolongation of Fully Major Histocompatibility Complex Mismatched Murine Cardiac Allograft by Shigyakusan.

Yin E, Uchiyama M, Niimi M.

Transplant Proc. 2018 Jan - Feb;50(1):274-282. doi: 10.1016/j.transproceed.2017.12.021.


Relationship Between Frequency of Spontaneous Swallowing and Salivary Substance P Level in Patients with Acute Stroke.

Niimi M, Hashimoto G, Hara T, Yamada N, Abo M, Fujigasaki H, Ide T.

Dysphagia. 2018 Aug;33(4):414-418. doi: 10.1007/s00455-017-9867-2. Epub 2017 Nov 28.


Principles and Applications of Rabbit Models for Atherosclerosis Research.

Fan J, Chen Y, Yan H, Niimi M, Wang Y, Liang J.

J Atheroscler Thromb. 2018 Mar 1;25(3):213-220. doi: 10.5551/jat.RV17018. Epub 2017 Oct 19. Review.


Effects of botulinum toxin A therapy and multidisciplinary rehabilitation on lower limb spasticity classified by spastic muscle echo intensity in post-stroke patients.

Hara T, Abo M, Hara H, Kobayashi K, Shimamoto Y, Shibata Y, Sasaki N, Yamada N, Niimi M.

Int J Neurosci. 2018 May;128(5):412-420. doi: 10.1080/00207454.2017.1389927. Epub 2017 Oct 23.


Comparative studies of three cholesteryl ester transfer proteins and their interactions with known inhibitors.

Wang Z, Niimi M, Ding Q, Liu Z, Wang L, Zhang J, Xu J, Fan J.

PLoS One. 2017 Aug 2;12(8):e0180772. doi: 10.1371/journal.pone.0180772. eCollection 2017.


Yogurt Feeding Induced the Prolongation of Fully Major Histocompatibility Complex-Mismatched Murine Cardiac Graft Survival by Induction of CD4+Foxp3+ Cells.

Uchiyama M, Yin E, Yanagisawa T, Jin X, Hara M, Matsuyama S, Imazuru T, Uchida K, Kawamura M, Niimi M.

Transplant Proc. 2017 Jul - Aug;49(6):1477-1482. doi: 10.1016/j.transproceed.2017.03.092.


Improvement of higher brain dysfunction after brain injury by repetitive transcranial magnetic stimulation and intensive rehabilitation therapy: case report.

Hara T, Abo M, Sasaki N, Yamada N, Niimi M, Kenmoku M, Kawakami K, Saito R.

Neuroreport. 2017 Sep 6;28(13):800-807. doi: 10.1097/WNR.0000000000000830.


The Efficacy of High-Frequency Repetitive Transcranial Magnetic Stimulation for Improving Apathy in Chronic Stroke Patients.

Sasaki N, Hara T, Yamada N, Niimi M, Kakuda W, Abo M.

Eur Neurol. 2017;78(1-2):28-32. doi: 10.1159/000477440. Epub 2017 Jun 3.


Increased Hepatic Expression of Endothelial Lipase Inhibits Cholesterol Diet-Induced Hypercholesterolemia and Atherosclerosis in Transgenic Rabbits.

Wang C, Nishijima K, Kitajima S, Niimi M, Yan H, Chen Y, Ning B, Matsuhisa F, Liu E, Zhang J, Chen YE, Fan J.

Arterioscler Thromb Vasc Biol. 2017 Jul;37(7):1282-1289. doi: 10.1161/ATVBAHA.117.309139. Epub 2017 May 25.


Deficiency of Cholesteryl Ester Transfer Protein Protects Against Atherosclerosis in Rabbits.

Zhang J, Niimi M, Yang D, Liang J, Xu J, Kimura T, Mathew AV, Guo Y, Fan Y, Zhu T, Song J, Ackermann R, Koike Y, Schwendeman A, Lai L, Pennathur S, Garcia-Barrio M, Fan J, Chen YE.

Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1068-1075. doi: 10.1161/ATVBAHA.117.309114. Epub 2017 Apr 20.


Glutathione inhibits antibody and complement-mediated immunologic cell injury via multiple mechanisms.

Zhang Z, Zhang X, Fang X, Niimi M, Huang Y, Piao H, Gao S, Fan J, Yao J.

Redox Biol. 2017 Aug;12:571-581. doi: 10.1016/j.redox.2017.03.030. Epub 2017 Mar 31.


Fungicide Xylaria sp. BCC 1067 extract induces reactive oxygen species and activates multidrug resistance system in Saccharomyces cerevisiae.

Somboon P, Poonsawad A, Wattanachaisaereekul S, Jensen LT, Niimi M, Cheevadhanarak S, Soontorngun N.

Future Microbiol. 2017 Apr;12:417-440. doi: 10.2217/fmb-2016-0151. Epub 2017 Mar 31.


Role of Ectopic Gene Conversion in the Evolution of a Candida krusei Pleiotropic Drug Resistance Transporter Family.

Lamping E, Zhu JY, Niimi M, Cannon RD.

Genetics. 2017 Apr;205(4):1619-1639. doi: 10.1534/genetics.116.194811. Epub 2017 Feb 3.


Continuous Intraoperative Neuromonitoring Study Using Pigs for the Prevention of Mechanical Recurrent Laryngeal Nerve Injury in Esophageal Surgery.

Deguchi T, Ikeda Y, Niimi M, Fukushima R, Kitajima M.

Surg Innov. 2017 Apr;24(2):115-121. doi: 10.1177/1553350617690304. Epub 2017 Jan 31.


Multi-institutional phase II study on the feasibility of liver resection following preoperative mFOLFOX6 therapy for resectable liver metastases from colorectal cancers.

Nagayama S, Hasegawa S, Hida K, Kawada K, Hatano E, Nakamura K, Seo S, Taura K, Yasuchika K, Matsuo T, Zaima M, Kanazawa A, Terajima H, Tada M, Adachi Y, Nishitai R, Manaka D, Yoshimura T, Doi K, Horimatsu T, Mitsuyoshi A, Yoshimura K, Niimi M, Matsumoto S, Sakai Y, Uemoto S.

Int J Clin Oncol. 2017 Apr;22(2):316-323. doi: 10.1007/s10147-016-1050-5. Epub 2016 Oct 17.


High-frequency rTMS on leg motor area in the early phase of stroke.

Sasaki N, Abo M, Hara T, Yamada N, Niimi M, Kakuda W.

Acta Neurol Belg. 2017 Mar;117(1):189-194. doi: 10.1007/s13760-016-0687-1. Epub 2016 Aug 9.


Comparison of Functional Outcome between Lacunar Infarction and Branch Atheromatous Disease in Lenticulostriate Artery Territory.

Niimi M, Abo M, Miyano S, Sasaki N, Hara T, Yamada N.

J Stroke Cerebrovasc Dis. 2016 Sep;25(9):2271-5. doi: 10.1016/j.jstrokecerebrovasdis.2016.05.015. Epub 2016 Jul 11.


Effects of botulinum toxin A therapy and multidisciplinary rehabilitation on upper and lower limb spasticity in post-stroke patients.

Hara T, Abo M, Hara H, Kobayashi K, Shimamoto Y, Samizo Y, Sasaki N, Yamada N, Niimi M.

Int J Neurosci. 2017 Jun;127(6):469-478. doi: 10.1080/00207454.2016.1196204. Epub 2016 Jun 27.


Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models.

Wang Z, Zhang J, Li H, Li J, Niimi M, Ding G, Chen H, Xu J, Zhang H, Xu Z, Dai Y, Gui T, Li S, Liu Z, Wu S, Cao M, Zhou L, Lu X, Wang J, Yang J, Fu Y, Yang D, Song J, Zhu T, Li S, Ning B, Wang Z, Koike T, Shiomi M, Liu E, Chen L, Fan J, Chen YE, Li Y.

Sci Rep. 2016 Jun 1;6:26942. doi: 10.1038/srep26942.


Identification and characterization of Candida utilis multidrug efflux transporter CuCdr1p.

Watanasrisin W, Iwatani S, Oura T, Tomita Y, Ikushima S, Chindamporn A, Niimi M, Niimi K, Lamping E, Cannon RD, Kajiwara S.

FEMS Yeast Res. 2016 Jun;16(4). pii: fow042. doi: 10.1093/femsyr/fow042. Epub 2016 May 1.


Suramin inhibits antibody binding to cell surface antigens and disrupts complement-mediated mesangial cell lysis.

Piao H, Chi Y, Zhang X, Zhang Z, Gao K, Niimi M, Kamiyama M, Zhang J, Takeda M, Yao J.

J Pharmacol Sci. 2016 Dec;132(4):224-234. doi: 10.1016/j.jphs.2016.03.011. Epub 2016 Mar 30.


Prevalence of Isolated Asymptomatic Deep Vein Thrombosis in Varicose Vein Patients with Superficial Thrombophlebitis: A Single Center Experience in Japan.

Shirasugi N, Horiguchi S, Shirato H, Kawakami T, Ono H, Yabuki S, Jojima K, Niimi M.

Ann Vasc Dis. 2016;9(1):2-7. doi: 10.3400/avd.oa.15-00124. Epub 2015 Dec 31.


Role of Brain-Derived Neurotrophic Factor in Beneficial Effects of Repetitive Transcranial Magnetic Stimulation for Upper Limb Hemiparesis after Stroke.

Niimi M, Hashimoto K, Kakuda W, Miyano S, Momosaki R, Ishima T, Abo M.

PLoS One. 2016 Mar 23;11(3):e0152241. doi: 10.1371/journal.pone.0152241. eCollection 2016.


Angiotensin II Destabilizes Coronary Plaques in Watanabe Heritable Hyperlipidemic Rabbits.

Li S, Wang YN, Niimi M, Ning B, Chen Y, Kang D, Wang Z, Yu Q, Waqar AB, Liu E, Zhang J, Shiomi M, Chen YE, Fan J.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):810-816. doi: 10.1161/ATVBAHA.115.306871. Epub 2016 Mar 17.


Identification and functional characterization of Penicillium marneffei pleiotropic drug resistance transporters ABC1 and ABC2.

Panapruksachat S, Iwatani S, Oura T, Vanittanakom N, Chindamporn A, Niimi K, Niimi M, Lamping E, Cannon RD, Kajiwara S.

Med Mycol. 2016 Jul 1;54(5):478-91. doi: 10.1093/mmy/myv117. Epub 2016 Jan 17.


ApoE knockout rabbits: A novel model for the study of human hyperlipidemia.

Niimi M, Yang D, Kitajima S, Ning B, Wang C, Li S, Liu E, Zhang J, Eugene Chen Y, Fan J.

Atherosclerosis. 2016 Feb;245:187-93. doi: 10.1016/j.atherosclerosis.2015.12.002. Epub 2015 Dec 9.


Food Restriction Prolongs Murine Cardiac Grafts.

Uchiyama M, Yin E, Jin X, Niimi M.

Transplant Proc. 2015 Oct;47(8):2528-32. doi: 10.1016/j.transproceed.2015.09.016.


Dietary cholesterol atherogenic changes in juvenile rabbits.

Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Itabe H, Yoshikawa T.

Biol Pharm Bull. 2015;38(5):785-8. doi: 10.1248/bpb.b14-00775.


Proton pump inhibitor after endoscopic resection for esophageal squamous cell cancer: multicenter prospective randomized controlled trial.

Kakushima N, Hori K, Ono H, Horimatsu T, Uedo N, Ohata K, Doyama H, Kaneko K, Oda I, Hikichi T, Kawahara Y, Niimi K, Takaki Y, Mizuno M, Yazumi S, Hosokawa A, Imagawa A, Niimi M, Yoshimura K, Muto M.

J Gastroenterol. 2016 Feb;51(2):104-11. doi: 10.1007/s00535-015-1085-9. Epub 2015 May 5.


Changes in oxalate and some mineral concentrations of Setaria sphacelata under cutting and uncutting conditions.

Rahman MM, Tateyama M, Niimi M, Abdullah RB, Khadijah WE, Kawamura O.

Pak J Biol Sci. 2014 Apr;17(4):586-9.


Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits.

Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, Shiomi M, Ye T, Dong S, Fan J.

J Appl Toxicol. 2015 Sep;35(9):1058-70. doi: 10.1002/jat.3103. Epub 2015 Jan 23.


Treadmill exercise induces murine cardiac allograft survival and generates regulatory T cell.

Uchiyama M, Jin X, Yin E, Shimokawa T, Niimi M.

Transpl Int. 2015 Mar;28(3):352-62. doi: 10.1111/tri.12491. Epub 2014 Dec 19.


Bisphenol A exposure enhances atherosclerosis in WHHL rabbits.

Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, Shiomi M, Ye T, Dong S, Fan J.

PLoS One. 2014 Oct 21;9(10):e110977. doi: 10.1371/journal.pone.0110977. eCollection 2014.


Drug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5.

Keniya MV, Holmes AR, Niimi M, Lamping E, Gillet JP, Gottesman MM, Cannon RD.

Mol Pharm. 2014 Oct 6;11(10):3452-62. doi: 10.1021/mp500230b. Epub 2014 Aug 22.


Fox smell abrogates the effect of herbal odor to prolong mouse cardiac allograft survival.

Jin X, Uchiyama M, Zhang Q, Niimi M.

J Cardiothorac Surg. 2014 May 9;9:82. doi: 10.1186/1749-8090-9-82.


Effect of 34 kinds of traditional Japanese herbal medicines on prolongation of cardiac allograft survival.

Jin X, Uchiyama M, Zhang Q, Harada T, Otsuka K, Shimokawa T, Niimi M.

Transplant Proc. 2014 May;46(4):1175-9. doi: 10.1016/j.transproceed.2014.01.007.


Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin.

Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Yasufuku R, Imaizumi A, Itabe H, Yoshikawa T.

PLoS One. 2014 May 8;9(5):e96929. doi: 10.1371/journal.pone.0096929. eCollection 2014.


Combination of paeoniae radix and cnidii rhizoma prolonged survival of fully mismatched cardiac allografts and generated regulatory cells in mice.

Jin X, Yu L, Uchiyama M, Yin E, Harada T, Otsuka K, Matsuyama S, Imazuru T, Shimokawa T, Niimi M.

Evid Based Complement Alternat Med. 2014;2014:841408. doi: 10.1155/2014/841408. Epub 2014 Mar 20.

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