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Items: 1 to 50 of 73

1.

Alpha-blockers as colorectal cancer chemopreventatives: findings from a case-control study, human cell cultures, and in vivo preclinical testing.

Suzuki N, Niikura R, Ihara S, Hikiba Y, Kinoshita H, Higashishima N, Hayakawa Y, Yamada A, Hirata Y, Nakata R, Okamoto M, Sano M, Kushiyama A, Ichinose M, Woods SL, Worthley D, Iwamoto Y, Koike K.

Cancer Prev Res (Phila). 2019 Jan 30. pii: canprevres.0288.2018. doi: 10.1158/1940-6207.CAPR-18-0288. [Epub ahead of print]

PMID:
30700439
2.

Automatic detection of erosions and ulcerations in wireless capsule endoscopy images based on a deep convolutional neural network.

Aoki T, Yamada A, Aoyama K, Saito H, Tsuboi A, Nakada A, Niikura R, Fujishiro M, Oka S, Ishihara S, Matsuda T, Tanaka S, Koike K, Tada T.

Gastrointest Endosc. 2019 Feb;89(2):357-363.e2. doi: 10.1016/j.gie.2018.10.027. Epub 2018 Oct 25.

PMID:
30670179
3.

Prediction of the Clinical Outcomes of Sigmoid Volvulus by Abdominal X-Ray: AXIS Classification System.

Ishibashi R, Niikura R, Obana N, Fukuda S, Tsuboi M, Aoki T, Yoshida S, Yamada A, Hirata Y, Koike K.

Gastroenterol Res Pract. 2018 Nov 15;2018:8493235. doi: 10.1155/2018/8493235. eCollection 2018.

4.

Speech Outcomes of 10-year-old Children after Early Palatoplasty Using Presurgical Orthodontics at 6 Months of Age.

Hanai U, Akamatsu T, Sakata N, Niikura R, Muramatsu H, Okawa T, Sakuma Y.

Tokai J Exp Clin Med. 2018 Dec 20;43(4):168-172.

5.

BHLHA15-positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice.

Hayakawa Y, Tsuboi M, Asfaha S, Kinoshita H, Niikura R, Konishi M, Hata M, Oya Y, Kim W, Middelhoff M, Hikiba Y, Higashijima N, Ihara S, Ushiku T, Fukayama M, Tailor Y, Hirata Y, Guha C, Yan KS, Koike K, Wang TC.

Gastroenterology. 2018 Nov 15. pii: S0016-5085(18)35272-7. doi: 10.1053/j.gastro.2018.11.024. [Epub ahead of print]

PMID:
30448068
6.

The Effects of Direct Oral Anticoagulants, Warfarin, Aspirin and Thienopyridine on the Performance of Immunochemical, Faecal, Occult Blood Tests.

Niikura R, Yamada A, Fujishiro M, Tanaka K, Matsuda K, Saito Y, Ohtsuka K, Oda I, Katada C, Kato M, Kida M, Kobayashi K, Hoteya S, Horimatsu T, Kodashima S, Matsuda T, Muto M, Yamamoto H, Ryozawa S, Iwakiri R, Kutsumi H, Miyata H, Kato M, Haruma K, Fujimoto K, Uemura N, Kaminishi M, Shinozaki T, Tajiri H, Koike K.

Digestion. 2018 Nov 8:1-10. doi: 10.1159/000494251. [Epub ahead of print]

PMID:
30408803
7.

Increased risk of non-AIDS-defining cancers in Asian HIV-infected patients: a long-term cohort study.

Nagata N, Nishijima T, Niikura R, Yokoyama T, Matsushita Y, Watanabe K, Teruya K, Kikuchi Y, Akiyama J, Yanase M, Uemura N, Oka S, Gatanaga H.

BMC Cancer. 2018 Nov 6;18(1):1066. doi: 10.1186/s12885-018-4963-8.

8.

Development and internal validation of a risk scoring system for gastrointestinal events requiring surgery in gastrointestinal lymphoma patients.

Aoki T, Yamada A, Takahashi M, Niikura R, Toyama K, Ushiku T, Kurokawa M, Momose T, Fukayama M, Koike K.

J Gastroenterol Hepatol. 2018 Aug 27. doi: 10.1111/jgh.14452. [Epub ahead of print]

PMID:
30151937
9.

Role of warfarin as a predictor of recurrent bleeding after negative small-bowel capsule endoscopy.

Niikura R, Yamada A, Hirata Y, Hayakawa Y, Suzuki H, Yamamoto S, Fujishiro M, Koike K.

Gastrointest Endosc. 2018 Sep;88(3):574-574.e2. doi: 10.1016/j.gie.2018.04.2344. No abstract available.

PMID:
30115312
10.

External validation of the NOBLADS score, a risk scoring system for severe acute lower gastrointestinal bleeding.

Aoki T, Yamada A, Nagata N, Niikura R, Hirata Y, Koike K.

PLoS One. 2018 Apr 26;13(4):e0196514. doi: 10.1371/journal.pone.0196514. eCollection 2018.

11.

A multicenter, randomized controlled trial comparing the identification rate of stigmata of recent hemorrhage and rebleeding rate between early and elective colonoscopy in outpatient-onset acute lower gastrointestinal bleeding: study protocol for a randomized controlled trial.

Niikura R, Nagata N, Yamada A, Doyama H, Shiratori Y, Nishida T, Kiyotoki S, Yada T, Fujita T, Sumiyoshi T, Hasatani K, Mikami T, Honda T, Mabe K, Hara K, Yamamoto K, Takeda M, Takata M, Tanaka M, Shinozaki T, Fujishiro M, Koike K.

Trials. 2018 Apr 3;19(1):214. doi: 10.1186/s13063-018-2558-y.

12.

Efficacy of Vonoprazan for Gastroesophageal Reflux Symptoms in Patients with Proton Pump Inhibitor-resistant Non-erosive Reflux Disease.

Niikura R, Yamada A, Hirata Y, Hayakawa Y, Takahashi A, Shinozaki T, Takeuchi Y, Fujishiro M, Koike K.

Intern Med. 2018 Sep 1;57(17):2443-2450. doi: 10.2169/internalmedicine.0492-17. Epub 2018 Mar 30.

13.

Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer.

Niikura R, Hayakawa Y, Hirata Y, Konishi M, Suzuki N, Ihara S, Yamada A, Ushiku T, Fujishiro M, Fukayama M, Koike K.

Cancer Prev Res (Phila). 2018 May;11(5):279-286. doi: 10.1158/1940-6207.CAPR-17-0276. Epub 2018 Feb 16.

PMID:
29453233
14.

Long-term proton pump inhibitor use is a risk factor of gastric cancer after treatment for Helicobacter pylori: a retrospective cohort analysis.

Niikura R, Hayakawa Y, Hirata Y, Yamada A, Fujishiro M, Koike K.

Gut. 2018 Oct;67(10):1908-1910. doi: 10.1136/gutjnl-2017-315710. Epub 2017 Dec 22. No abstract available.

PMID:
29273641
15.

Etiology and long-term rebleeding of endoscopic ulcerative lesions in the small bowel in patients with obscure gastrointestinal bleeding: A multicenter cohort study.

Aoki T, Yamada A, Hirata Y, Suzuki H, Nakada A, Niikura R, Seto M, Okamoto M, Koike K.

J Gastroenterol Hepatol. 2018 Jul;33(7):1327-1334. doi: 10.1111/jgh.14068. Epub 2018 Feb 27.

PMID:
29231993
16.

Colonoscopy reduces colorectal cancer mortality: A multicenter, long-term, colonoscopy-based cohort study.

Niikura R, Hirata Y, Suzuki N, Yamada A, Hayakawa Y, Suzuki H, Yamamoto S, Nakata R, Komatsu J, Okamoto M, Kodaira M, Shinozaki T, Fujishiro M, Watanabe T, Koike K.

PLoS One. 2017 Sep 28;12(9):e0185294. doi: 10.1371/journal.pone.0185294. eCollection 2017.

17.

Therapeutic endoscopy-related GI bleeding and thromboembolic events in patients using warfarin or direct oral anticoagulants: results from a large nationwide database analysis.

Nagata N, Yasunaga H, Matsui H, Fushimi K, Watanabe K, Akiyama J, Uemura N, Niikura R.

Gut. 2018 Oct;67(10):1805-1812. doi: 10.1136/gutjnl-2017-313999. Epub 2017 Sep 5.

18.

Proton pump inhibitor therapy did not increase the prevalence of small-bowel injury: A propensity-matched analysis.

Yamada A, Niikura R, Maki K, Nakamura M, Watabe H, Fujishiro M, Oka S, Fujimori S, Nakajima A, Ohmiya N, Matsumoto T, Tanaka S, Koike K, Sakamoto C.

PLoS One. 2017 Aug 3;12(8):e0182586. doi: 10.1371/journal.pone.0182586. eCollection 2017.

19.

Associations between drugs and small-bowel mucosal bleeding: Multicenter capsule-endoscopy study.

Niikura R, Yamada A, Maki K, Nakamura M, Watabe H, Fujishiro M, Oka S, Esaki M, Fujimori S, Nakajima A, Ohmiya N, Matsumoto T, Tanaka S, Koike K, Sakamoto C.

Dig Endosc. 2018 Jan;30(1):79-89. doi: 10.1111/den.12922. Epub 2017 Sep 4.

PMID:
28719079
20.

Diagnostic capability of colon capsule endoscopy for advanced colorectal cancer: A pilot study.

Ota Y, Yamada A, Kobayashi Y, Niikura R, Shimpoh T, Narita A, Yoshida S, Suzuki N, Watabe H, Hirata Y, Ishihara S, Sunami E, Watanabe T, Koike K.

Dig Endosc. 2017 Sep;29(6):695-701. doi: 10.1111/den.12862. Epub 2017 Apr 24.

PMID:
28295697
21.

Association between gastric cancer and the Kyoto classification of gastritis.

Shichijo S, Hirata Y, Niikura R, Hayakawa Y, Yamada A, Koike K.

J Gastroenterol Hepatol. 2017 Sep;32(9):1581-1586. doi: 10.1111/jgh.13764.

PMID:
28217843
22.

The incidence of post-colonoscopy colorectal cancer: a retrospective long-term cohort study using a colonoscopy database.

Nakada A, Niikura R, Yamada A, Yoshida S, Hirata Y, Koike K.

Int J Colorectal Dis. 2017 Jun;32(6):839-845. doi: 10.1007/s00384-017-2757-0. Epub 2017 Jan 14.

PMID:
28091843
23.

Current state of practice for colonic diverticular bleeding in 37 hospitals in Japan: A multicenter questionnaire study.

Niikura R, Nagata N, Doyama H, Ota R, Ishii N, Mabe K, Nishida T, Hikichi T, Sumiyama K, Nishikawa J, Uraoka T, Kiyotoki S, Fujishiro M, Koike K.

World J Gastrointest Endosc. 2016 Dec 16;8(20):785-794. doi: 10.4253/wjge.v8.i20.785.

24.

Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling.

Hayakawa Y, Sakitani K, Konishi M, Asfaha S, Niikura R, Tomita H, Renz BW, Tailor Y, Macchini M, Middelhoff M, Jiang Z, Tanaka T, Dubeykovskaya ZA, Kim W, Chen X, Urbanska AM, Nagar K, Westphalen CB, Quante M, Lin CS, Gershon MD, Hara A, Zhao CM, Chen D, Worthley DL, Koike K, Wang TC.

Cancer Cell. 2017 Jan 9;31(1):21-34. doi: 10.1016/j.ccell.2016.11.005. Epub 2016 Dec 15.

25.

Development and Validation of a Risk Scoring System for Severe Acute Lower Gastrointestinal Bleeding.

Aoki T, Nagata N, Shimbo T, Niikura R, Sakurai T, Moriyasu S, Okubo H, Sekine K, Watanabe K, Yokoi C, Yanase M, Akiyama J, Mizokami M, Uemura N.

Clin Gastroenterol Hepatol. 2016 Nov;14(11):1562-1570.e2. doi: 10.1016/j.cgh.2016.05.042. Epub 2016 Jun 14.

PMID:
27311620
26.

Vonoprazan versus conventional proton pump inhibitor-based triple therapy as first-line treatment against Helicobacter pylori: A multicenter retrospective study in clinical practice.

Shichijo S, Hirata Y, Niikura R, Hayakawa Y, Yamada A, Mochizuki S, Matsuo K, Isomura Y, Seto M, Suzuki N, Suzuki H, Yamamoto S, Sugimoto T, Omae T, Okamoto M, Watabe H, Togo G, Takano N, Fukui K, Ito Y, Koike K.

J Dig Dis. 2016 Oct;17(10):670-675. doi: 10.1111/1751-2980.12398.

PMID:
27534444
27.

Safety of Regular-Dose Imatinib Therapy in Patients with Gastrointestinal Stromal Tumors Undergoing Dialysis.

Niikura R, Serizawa T, Yamada A, Yoshida S, Tanaka M, Hirata Y, Koike K.

Case Rep Gastroenterol. 2016 May 19;10(1):17-23. doi: 10.1159/000443267. eCollection 2016 Jan-Apr.

28.

Factors predicting adverse events associated with therapeutic colonoscopy for colorectal neoplasia: a retrospective nationwide study in Japan.

Niikura R, Yasunaga H, Yamada A, Matsui H, Fushimi K, Hirata Y, Koike K.

Gastrointest Endosc. 2016 Dec;84(6):971-982.e6. doi: 10.1016/j.gie.2016.05.013. Epub 2016 May 14.

PMID:
27189658
29.

Histologic intestinal metaplasia and endoscopic atrophy are predictors of gastric cancer development after Helicobacter pylori eradication.

Shichijo S, Hirata Y, Niikura R, Hayakawa Y, Yamada A, Ushiku T, Fukayama M, Koike K.

Gastrointest Endosc. 2016 Oct;84(4):618-24. doi: 10.1016/j.gie.2016.03.791. Epub 2016 Mar 16.

PMID:
26995689
30.

Acute Middle Gastrointestinal Bleeding Risk Associated with NSAIDs, Antithrombotic Drugs, and PPIs: A Multicenter Case-Control Study.

Nagata N, Niikura R, Yamada A, Sakurai T, Shimbo T, Kobayashi Y, Okamoto M, Mitsuno Y, Ogura K, Hirata Y, Fujimoto K, Akiyama J, Uemura N, Koike K.

PLoS One. 2016 Mar 15;11(3):e0151332. doi: 10.1371/journal.pone.0151332. eCollection 2016.

31.

Safety and Effectiveness of Early Colonoscopy in Management of Acute Lower Gastrointestinal Bleeding on the Basis of Propensity Score Matching Analysis.

Nagata N, Niikura R, Sakurai T, Shimbo T, Aoki T, Moriyasu S, Sekine K, Okubo H, Imbe K, Watanabe K, Yokoi C, Yanase M, Akiyama J, Uemura N.

Clin Gastroenterol Hepatol. 2016 Apr;14(4):558-64. doi: 10.1016/j.cgh.2015.10.011. Epub 2015 Oct 19.

PMID:
26492844
32.

New predictive model of rebleeding during follow-up of patents with obscure gastrointestinal bleeding: A multicenter cohort study.

Niikura R, Yamada A, Nagata N, Kobayashi Y, Okamoto M, Mitsuno Y, Ogura K, Yoshida S, Shimbo T, Hirata Y, Koike K.

J Gastroenterol Hepatol. 2016 Apr;31(4):752-60. doi: 10.1111/jgh.13201.

PMID:
26487158
33.

Risk factors for adverse in-hospital outcomes in acute colonic diverticular hemorrhage.

Nagata N, Niikura R, Aoki T, Moriyasu S, Sakurai T, Shimbo T, Sekine K, Okubo H, Watanabe K, Yokoi C, Akiyama J, Yanase M, Mizokami M, Fujimoto K, Uemura N.

World J Gastroenterol. 2015 Oct 7;21(37):10697-703. doi: 10.3748/wjg.v21.i37.10697.

34.

Adverse Events during Bowel Preparation and Colonoscopy in Patients with Acute Lower Gastrointestinal Bleeding Compared with Elective Non-Gastrointestinal Bleeding.

Niikura R, Nagata N, Shimbo T, Sakurai T, Aoki T, Moriyasu S, Sekine K, Okubo H, Watanabe K, Yokoi C, Yamada A, Hirata Y, Koike K, Akiyama J, Uemura N.

PLoS One. 2015 Sep 14;10(9):e0138000. doi: 10.1371/journal.pone.0138000. eCollection 2015.

35.

Prevalence of Anal Human Papillomavirus Infection and Risk Factors among HIV-positive Patients in Tokyo, Japan.

Nagata N, Watanabe K, Nishijima T, Tadokoro K, Watanabe K, Shimbo T, Niikura R, Sekine K, Akiyama J, Teruya K, Gatanaga H, Kikuchi Y, Uemura N, Oka S.

PLoS One. 2015 Sep 14;10(9):e0137434. doi: 10.1371/journal.pone.0137434. eCollection 2015.

36.

Endoscopic management of colonic diverticular bleeding.

Yamada A, Niikura R, Yoshida S, Hirata Y, Koike K.

Dig Endosc. 2015 Nov;27(7):720-5. doi: 10.1111/den.12534. Epub 2015 Sep 8. Review.

PMID:
26258405
37.

Risk factors for small bowel angioectasia: The impact of visceral fat accumulation.

Yamada A, Niikura R, Kobayashi Y, Suzuki H, Yoshida S, Watabe H, Yamaji Y, Hirata Y, Koike K.

World J Gastroenterol. 2015 Jun 21;21(23):7242-7. doi: 10.3748/wjg.v21.i23.7242.

38.

Visceral fat accumulation affects risk of colonic diverticular hemorrhage.

Nagata N, Sakamoto K, Arai T, Niikura R, Shimbo T, Shinozaki M, Aoki T, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Yanase M, Akiyama J, Noda M, Uemura N.

Int J Colorectal Dis. 2015 Oct;30(10):1399-406. doi: 10.1007/s00384-015-2295-6. Epub 2015 Jun 24.

PMID:
26099321
39.

Effect of body mass index and intra-abdominal fat measured by computed tomography on the risk of bowel symptoms.

Nagata N, Sakamoto K, Arai T, Niikura R, Shimbo T, Shinozaki M, Ihana N, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Yanase M, Akiyama J, Uemura N, Noda M.

PLoS One. 2015 Apr 23;10(4):e0123993. doi: 10.1371/journal.pone.0123993. eCollection 2015.

40.

Role of urgent contrast-enhanced multidetector computed tomography for acute lower gastrointestinal bleeding in patients undergoing early colonoscopy.

Nagata N, Niikura R, Aoki T, Moriyasu S, Sakurai T, Shimbo T, Shinozaki M, Sekine K, Okubo H, Watanabe K, Yokoi C, Yanase M, Akiyama J, Uemura N.

J Gastroenterol. 2015 Dec;50(12):1162-72. doi: 10.1007/s00535-015-1069-9. Epub 2015 Mar 27.

PMID:
25812518
41.

Distribution of intestinal metaplasia as a predictor of gastric cancer development.

Shichijo S, Hirata Y, Sakitani K, Yamamoto S, Serizawa T, Niikura R, Watabe H, Yoshida S, Yamada A, Yamaji Y, Ushiku T, Fukayama M, Koike K.

J Gastroenterol Hepatol. 2015 Aug;30(8):1260-4. doi: 10.1111/jgh.12946.

PMID:
25777777
42.

Association between colonic diverticulosis and bowel symptoms: A case-control study of 1629 Asian patients.

Nagata N, Niikura R, Aoki T, Shimbo T, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Yanase M, Akiyama J, Uemura N.

J Gastroenterol Hepatol. 2015 Aug;30(8):1252-9. doi: 10.1111/jgh.12941.

PMID:
25777157
43.

Natural history of bleeding risk in colonic diverticulosis patients: a long-term colonoscopy-based cohort study.

Niikura R, Nagata N, Shimbo T, Aoki T, Yamada A, Hirata Y, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Mizokami M, Yanase M, Akiyama J, Koike K, Uemura N.

Aliment Pharmacol Ther. 2015 May;41(9):888-94. doi: 10.1111/apt.13148. Epub 2015 Feb 26.

44.

Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin.

Nagata N, Niikura R, Aoki T, Sakurai T, Moriyasu S, Shimbo T, Sekine K, Okubo H, Watanabe K, Yokoi C, Yanase M, Akiyama J, Uemura N.

J Gastroenterol. 2015 Nov;50(11):1079-86. doi: 10.1007/s00535-015-1055-2. Epub 2015 Feb 21.

PMID:
25700638
45.

Abdominal Fat Accumulation, as Measured by Computed Tomography, Increases the Risk of Ischemic Colitis: A Retrospective Case-Control Study.

Aoki T, Nagata N, Sakamoto K, Arai T, Niikura R, Shimbo T, Shinozaki M, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Mizokami M, Noda M, Uemura N.

Dig Dis Sci. 2015 Jul;60(7):2104-11. doi: 10.1007/s10620-015-3555-6. Epub 2015 Feb 4.

PMID:
25648643
46.

Impact of discontinuing non-steroidal antiinflammatory drugs on long-term recurrence in colonic diverticular bleeding.

Nagata N, Niikura R, Aoki T, Shimbo T, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Mizokami M, Uemura N.

World J Gastroenterol. 2015 Jan 28;21(4):1292-8. doi: 10.3748/wjg.v21.i4.1292.

47.

Latent inhibition in rats neonatally treated chronically with MK-801: differential effects on conditioned taste aversion and conditioned emotional response.

Niikura R, Nozawa T, Yamada K, Kato K, Ichitani Y.

Behav Brain Res. 2015 Apr 15;283:102-7. doi: 10.1016/j.bbr.2015.01.029. Epub 2015 Jan 25.

PMID:
25629943
48.

High-dose barium impaction therapy for the recurrence of colonic diverticular bleeding: a randomized controlled trial.

Nagata N, Niikura R, Shimbo T, Ishizuka N, Yamano K, Mizuguchi K, Akiyama J, Yanase M, Mizokami M, Uemura N.

Ann Surg. 2015 Feb;261(2):269-75. doi: 10.1097/SLA.0000000000000658. Erratum in: Ann Surg. 2016 Mar;263(3):e58.

PMID:
25569028
49.

Natural history of outpatient-onset ischemic colitis compared with other lower gastrointestinal bleeding: a long-term cohort study.

Nagata N, Niikura R, Aoki T, Shimbo T, Kishida Y, Sekine K, Tanaka S, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Mizokami M, Uemura N.

Int J Colorectal Dis. 2015 Feb;30(2):243-9. doi: 10.1007/s00384-014-2079-4. Epub 2014 Nov 30.

PMID:
25433819
50.

Visceral Abdominal Obesity Measured by Computed Tomography is Associated With Increased Risk of Colonic Diverticulosis.

Nagata N, Sakamoto K, Arai T, Niikura R, Shimbo T, Shinozaki M, Aoki T, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Noda M, Itoh T, Mizokami M, Uemura N.

J Clin Gastroenterol. 2015 Nov-Dec;49(10):816-22. doi: 10.1097/MCG.0000000000000267.

PMID:
25412157

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