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Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes.

Exner ND, Valenzuela JAC, Abou-El-Ardat K, Miletic H, Huszthy PC, Radehaus PM, Schröck E, Bjerkvig R, Kaderali L, Klink B, Nigro JM.

Oncotarget. 2019 Jun 4;10(38):3641-3653. doi: 10.18632/oncotarget.26950. eCollection 2019 Jun 4.


Single-ventricle reconstruction 2.0: A closer look at our understanding of care for infants undergoing the Norwood procedure.

Karamlou T, Meza JM, Najm HK, Nigro JJ, Hill KD.

J Thorac Cardiovasc Surg. 2019 Apr 17. pii: S0022-5223(19)30808-6. doi: 10.1016/j.jtcvs.2018.12.121. [Epub ahead of print] No abstract available.


Hepatic Vein Incorporation Into the Azygos System in Heterotaxy and Interrupted Inferior Vena Cava.

Montesa C, Karamlou T, Ratnayaka K, Pophal SG, Ryan J, Nigro JJ.

World J Pediatr Congenit Heart Surg. 2019 May;10(3):330-337. doi: 10.1177/2150135119842869.


Dead space fractions in neonates following first-stage palliation for hypoplastic left heart syndrome.

Anton-Martin P, Joshi R, Rao M, Pandurangi S, Wellnitz C, Kang P, Nigro JJ, Velez D, Willis BC.

Cardiol Young. 2019 Apr;29(4):481-487. doi: 10.1017/S1047951119000076. Epub 2019 Apr 17.


3D printing for congenital heart disease: a single site's initial three-yearexperience.

Ryan J, Plasencia J, Richardson R, Velez D, Nigro JJ, Pophal S, Frakes D.

3D Print Med. 2018 Nov 8;4(1):10. doi: 10.1186/s41205-018-0033-8.


Secreted and intracellular cytokines are complementary measures for human monocytes treated with Toll-like receptor agonists.

Song Y, Nigro J, Yu L, Congiu M, Skinner N, Thompson A, Visvanathan K.

J Immunol Methods. 2019 Jan;464:131-137. doi: 10.1016/j.jim.2018.11.003. Epub 2018 Nov 3.


Alternative methods for virtual heart transplant-Size matching for pediatric heart transplantation with and without donor medical images available.

Plasencia JD, Kamarianakis Y, Ryan JR, Karamlou T, Park SS, Nigro JJ, Frakes DH, Pophal SG, Lagerstrom CF, Velez DA, Zangwill SD.

Pediatr Transplant. 2018 Dec;22(8):e13290. doi: 10.1111/petr.13290. Epub 2018 Sep 24.


Pulmonary Dead Space Fraction and Extubation Success in Children After Cardiac Surgery.

Devor RL, Kang P, Wellnitz C, Nigro JJ, Velez DA, Willis BC.

Pediatr Crit Care Med. 2018 Apr;19(4):301-309. doi: 10.1097/PCC.0000000000001456.


Invited Commentary.

Karamlou T, Velez D, Nigro JJ.

Ann Thorac Surg. 2017 Nov;104(5):1629. doi: 10.1016/j.athoracsur.2017.04.034. No abstract available.


Encrypted prediction: A hacker's perspective.

Karamlou T, Velez DA, Nigro JJ.

J Thorac Cardiovasc Surg. 2017 Dec;154(6):2038-2040. doi: 10.1016/j.jtcvs.2017.08.112. Epub 2017 Sep 9. No abstract available.


An apology or absolution for cerebral near-infrared spectroscopy: Can we get on the same wavelength?

Rao R, Nigro JJ, Karamlou T.

J Thorac Cardiovasc Surg. 2017 Sep;154(3):1063-1064. doi: 10.1016/j.jtcvs.2017.04.023. Epub 2017 Apr 23. No abstract available.


Integration of Hybrid and Single Ventricle Rehabilitation Techniques to Treat a Neonate After Iatrogenic Mitral Injury.

Ashfaq A, Seckeler M, Pophal S, Rhee E, Ryan J, Rao R, Klewer S, Nigro JJ.

World J Pediatr Congenit Heart Surg. 2016 Jul;7(4):498-501. doi: 10.1177/2150135115604469. Epub 2016 Feb 10.


The role of CD44 in fetal and adult hematopoietic stem cell regulation.

Cao H, Heazlewood SY, Williams B, Cardozo D, Nigro J, Oteiza A, Nilsson SK.

Haematologica. 2016 Jan;101(1):26-37. doi: 10.3324/haematol.2015.135921. Epub 2015 Nov 6.


A novel approach to neonatal management of tetralogy of Fallot, with pulmonary atresia, and multiple aortopulmonary collaterals.

Ryan JR, Moe TG, Richardson R, Frakes DH, Nigro JJ, Pophal S.

JACC Cardiovasc Imaging. 2015 Jan;8(1):103-104. doi: 10.1016/j.jcmg.2014.04.030. Epub 2014 Nov 12. No abstract available.


Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification.

Sheen CR, Kuss P, Narisawa S, Yadav MC, Nigro J, Wang W, Chhea TN, Sergienko EA, Kapoor K, Jackson MR, Hoylaerts MF, Pinkerton AB, O'Neill WC, Millán JL.

J Bone Miner Res. 2015 May;30(5):824-36. doi: 10.1002/jbmr.2420.


Design of non-aggregating variants of Aβ peptide.

Caine JM, Churches Q, Waddington L, Nigro J, Breheney K, Masters CL, Nuttall SD, Streltsov VA.

Biochem Biophys Res Commun. 2014 Oct 24;453(3):449-54. doi: 10.1016/j.bbrc.2014.09.102. Epub 2014 Oct 1.


Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.

Lai L, Leone TC, Keller MP, Martin OJ, Broman AT, Nigro J, Kapoor K, Koves TR, Stevens R, Ilkayeva OR, Vega RB, Attie AD, Muoio DM, Kelly DP.

Circ Heart Fail. 2014 Nov;7(6):1022-31. doi: 10.1161/CIRCHEARTFAILURE.114.001469. Epub 2014 Sep 18.


Retrograde cardioplegia for myocardial protection during arterial switch operation.

Nigro JJ, Velez DA.

Ann Thorac Surg. 2014 Jun;97(6):2233-4. doi: 10.1016/j.athoracsur.2013.10.102. No abstract available.


Clinicopathologic features of pediatric oligodendrogliomas: a series of 50 patients.

Rodriguez FJ, Tihan T, Lin D, McDonald W, Nigro J, Feuerstein B, Jackson S, Cohen K, Burger PC.

Am J Surg Pathol. 2014 Aug;38(8):1058-70. doi: 10.1097/PAS.0000000000000221.


Comparison of alternative nucleophiles for Sortase A-mediated bioconjugation and application in neuronal cell labelling.

Baer S, Nigro J, Madej MP, Nisbet RM, Suryadinata R, Coia G, Hong LP, Adams TE, Williams CC, Nuttall SD.

Org Biomol Chem. 2014 May 7;12(17):2675-85. doi: 10.1039/c3ob42325e.


Tumor versus stromal cells in culture--survival of the fittest?

Talasila KM, Brekka N, Mangseth K, Stieber D, Evensen L, Rosland GV, Torsvik A, Wagner M, Niclou SP, Mahesparan R, Vintermyr OK, Bjerkvig R, Nigro JM, Miletic H.

PLoS One. 2013 Dec 2;8(12):e81183. doi: 10.1371/journal.pone.0081183. eCollection 2013.


Vitamin D2-enriched button mushroom (Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic mice.

Bennett L, Kersaitis C, Macaulay SL, Münch G, Niedermayer G, Nigro J, Payne M, Sheean P, Vallotton P, Zabaras D, Bird M.

PLoS One. 2013 Oct 18;8(10):e76362. doi: 10.1371/journal.pone.0076362. eCollection 2013.


Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing.

Eisenreich S, Abou-El-Ardat K, Szafranski K, Campos Valenzuela JA, Rump A, Nigro JM, Bjerkvig R, Gerlach EM, Hackmann K, Schröck E, Krex D, Kaderali L, Schackert G, Platzer M, Klink B.

PLoS One. 2013 Sep 27;8(9):e76623. doi: 10.1371/journal.pone.0076623. eCollection 2013.


Sickle cell disease and complex congenital cardiac surgery: a case report and review of the pathophysiology and perioperative management.

Sanders DB, Smith BP, Sowell SR, Nguyen DH, Derby C, Eshun F, Nigro JJ.

Perfusion. 2014 Mar;29(2):153-8. doi: 10.1177/0267659113499599. Epub 2013 Jul 30. Review.


Total artificial heart in the pediatric patient with biventricular heart failure.

Park SS, Sanders DB, Smith BP, Ryan J, Plasencia J, Osborn MB, Wellnitz CM, Southard RN, Pierce CN, Arabia FA, Lane J, Frakes D, Velez DA, Pophal SG, Nigro JJ.

Perfusion. 2014 Jan;29(1):82-8. doi: 10.1177/0267659113496580. Epub 2013 Jul 18.


The failing Fontan: what's NEXT...?

Sanders DB, Sowell SR, Park SS, Derby C, Willis BC, Lane JE, Pierce CN, Arabia FA, Pophal SG, Nigro JJ.

Perfusion. 2014 Jan;29(1):89-93. doi: 10.1177/0267659113495913. Epub 2013 Jul 10.


Central amyloid-β-specific single chain variable fragment ameliorates Aβ aggregation and neurotoxicity.

Nisbet RM, Nigro J, Breheney K, Caine J, Hattarki MK, Nuttall SD.

Protein Eng Des Sel. 2013 Oct;26(10):571-80. doi: 10.1093/protein/gzt025. Epub 2013 Jun 13.


Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization.

Ryan TM, Caine J, Mertens HD, Kirby N, Nigro J, Breheney K, Waddington LJ, Streltsov VA, Curtain C, Masters CL, Roberts BR.

PeerJ. 2013 May 7;1:e73. doi: 10.7717/peerj.73. Print 2013.


A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

Klink B, Miletic H, Stieber D, Huszthy PC, Campos Valenzuela JA, Balss J, Wang J, Schubert M, Sakariassen PØ, Sundstrøm T, Torsvik A, Aarhus M, Mahesparan R, von Deimling A, Kaderali L, Niclou SP, Schröck E, Bjerkvig R, Nigro JM.

PLoS One. 2013;8(3):e59773. doi: 10.1371/journal.pone.0059773. Epub 2013 Mar 19. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/72a01ce5-b0ad-4cbd-ac77-0a81347a3940. Valenzuela, Jaime Alberto Campos [corrected to Campos Valenzuela, Jaime Alberto].


The role of extracorporeal life support in acute myocarditis: a bridge to recovery?

Sanders DB, Sowell SR, Willis B, Lane J, Pierce C, Pophal S, Arabia FA, Nigro JJ.

J Extra Corpor Technol. 2012 Dec;44(4):205-9.


EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis.

Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Stieber D, Keunen O, Brekka N, Moen I, Nigro JM, Vintermyr OK, Lund-Johansen M, Niclou S, Mørk SJ, Enger PO, Bjerkvig R, Miletic H.

Acta Neuropathol. 2013 May;125(5):683-98. doi: 10.1007/s00401-013-1101-1. Epub 2013 Feb 22.


Atrial septal hematoma after mitral valve and left coronary artery surgery in a child.

Naidu DP, Nigro J, Alboliras ET.

Pediatr Cardiol. 2013;34(8):2037-9. doi: 10.1007/s00246-012-0583-2. Epub 2012 Nov 24.


In vivo models of primary brain tumors: pitfalls and perspectives.

Huszthy PC, Daphu I, Niclou SP, Stieber D, Nigro JM, Sakariassen PØ, Miletic H, Thorsen F, Bjerkvig R.

Neuro Oncol. 2012 Aug;14(8):979-93. doi: 10.1093/neuonc/nos135. Epub 2012 Jun 7. Review.


Neonatal surgical reconstruction and peri-operative care for hypoplastic left heart syndrome: current strategies.

Fuller S, Ghanayem N, Chai P, Nigro J, Kleisli T, Tabbutt S.

Cardiol Young. 2011 Dec;21 Suppl 2:38-46. doi: 10.1017/S1047951111001569. Review.


Glycomic analyses of ovarian follicles during development and atresia.

Hatzirodos N, Nigro J, Irving-Rodgers HF, Vashi AV, Hummitzsch K, Caterson B, Sullivan TR, Rodgers RJ.

Matrix Biol. 2012 Jan;31(1):45-56. doi: 10.1016/j.matbio.2011.10.002. Epub 2011 Oct 19.


Impact of heparan sulfate chains and sulfur-mediated bonds on the mechanical properties of bovine lens capsule.

Dyksterhuis LB, White JF, Hickey M, Kirby N, Mudie S, Hawley A, Vashi A, Nigro J, Werkmeister JA, Ramshaw JA.

Biophys J. 2011 May 4;100(9):2077-83. doi: 10.1016/j.bpj.2011.03.020. Erratum in: Biophys J. 2011 Jun 8;100(11):2852. Dyksterhuis, L D [corrected to Dyksterhuis, L B].


NASA-modified precipitation products to improve USEPA nonpoint source water quality modeling for the Chesapeake Bay.

Nigro J, Toll D, Partington E, Ni-Meister W, Lee S, Gutierrez-Magness A, Engman T, Arsenault K.

J Environ Qual. 2010 Jul-Aug;39(4):1388-401.


The effect of bovine endosteum-derived particles on the proliferation of human mesenchymal stem cells.

Nigro J, White JF, Ramshaw JA, Haylock DN, Nilsson SK, Werkmeister JA.

Biomaterials. 2010 Jul;31(21):5689-99. doi: 10.1016/j.biomaterials.2010.03.054.


Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma.

Costa BM, Smith JS, Chen Y, Chen J, Phillips HS, Aldape KD, Zardo G, Nigro J, James CD, Fridlyand J, Reis RM, Costello JF.

Cancer Res. 2010 Jan 15;70(2):453-62. doi: 10.1158/0008-5472.CAN-09-2189. Epub 2010 Jan 12.


Nasal valve: anatomy and physiology.

Nigro CE, Nigro JF, Mion O, Mello JF Jr.

Braz J Otorhinolaryngol. 2009 Mar-Apr;75(2):305-10. Review.


Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines.

de la Motte C, Nigro J, Vasanji A, Rho H, Kessler S, Bandyopadhyay S, Danese S, Fiocchi C, Stern R.

Am J Pathol. 2009 Jun;174(6):2254-64. doi: 10.2353/ajpath.2009.080831. Epub 2009 May 14.


Regulation of heparan sulfate and chondroitin sulfate glycosaminoglycan biosynthesis by 4-fluoro-glucosamine in murine airway smooth muscle cells.

Nigro J, Wang A, Mukhopadhyay D, Lauer M, Midura RJ, Sackstein R, Hascall VC.

J Biol Chem. 2009 Jun 19;284(25):16832-9. doi: 10.1074/jbc.M109.002956. Epub 2009 Apr 3.


Prolonged use of dexmedetomidine in the paediatric cardiothoracic intensive care unit.

Bejian S, Valasek C, Nigro JJ, Cleveland DC, Willis BC.

Cardiol Young. 2009 Feb;19(1):98-104. doi: 10.1017/S1047951109003515. Epub 2009 Jan 20.


Surveys of rodent-borne disease in Thailand with a focus on scrub typhus assessment.

Lerdthusnee K, Nigro J, Monkanna T, Leepitakrat W, Leepitakrat S, Insuan S, Charoensongsermkit W, Khlaimanee N, Akkagraisee W, Chayapum K, Jones JW.

Integr Zool. 2008 Dec;3(4):267-73. doi: 10.1111/j.1749-4877.2008.00100.x.


Different application volumes of ethyl-cyanoacrylate tissue adhesive can change its antibacterial effects against ocular pathogens in vitro.

Romero IL, Paiato TP, Silva CB, Nigro JB, Malta S, Jenne Mimica LM, Soong HK, Hida RY.

Curr Eye Res. 2008 Oct;33(10):813-8. doi: 10.1080/02713680802437692.


Therapeutic options in hypertrophic cardiomyopathy: a pediatric perspective.

Rhee EK, Nigro JJ, Pophal SG.

Curr Treat Options Cardiovasc Med. 2008 Sep;10(5):433-41.


Meteorological, environmental remote sensing and neural network analysis of the epidemiology of malaria transmission in Thailand.

Kiang R, Adimi F, Soika V, Nigro J, Singhasivanon P, Sirichaisinthop J, Leemingsawat S, Apiwathnasorn C, Looareesuwan S.

Geospat Health. 2006 Nov;1(1):71-84.


The effect of PPAR ligands to modulate glucose metabolism alters the incorporation of metabolic precursors into proteoglycans synthesized by human vascular smooth muscle cells.

Nigro J, Potter-Perigo S, Ivey ME, de Dios ST, Evanko SP, Wight TN, Little PJ.

Arch Physiol Biochem. 2008 Jul;114(3):171-7. doi: 10.1080/13813450802181013 .


Phosphorylated troglitazone activates PPARgamma and inhibits vascular smooth muscle cell proliferation and proteoglycan synthesis.

Little PJ, Ballinger ML, Survase S, Osman N, Ogru E, Geytenbeek S, Bruemmer D, Nigro J.

J Cardiovasc Pharmacol. 2008 Mar;51(3):274-9. doi: 10.1097/FJC.0b013e3181626ce7.


Angiotensin II increases the expression of the transcription factor ETS-1 in mesangial cells.

Pearse DD, Tian RX, Nigro J, Iorgulescu JB, Puzis L, Jaimes EA.

Am J Physiol Renal Physiol. 2008 May;294(5):F1094-100. doi: 10.1152/ajprenal.00458.2007. Epub 2008 Mar 12.

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