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Items: 22


Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.

Wiersma M, Bussiere M, Halsall JA, Turan N, Slany R, Turner BM, Nightingale KP.

Epigenetics Chromatin. 2016 Nov 11;9:52. eCollection 2016.


Podcasting in the STEM disciplines: the implications of supplementary lecture recording and 'lecture flipping'.

Hadjianastasis M, Nightingale KP.

FEMS Microbiol Lett. 2016 Feb;363(4). pii: fnw006. doi: 10.1093/femsle/fnw006. Epub 2016 Jan 12. Review.


The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing.

Boudadi E, Stower H, Halsall JA, Rutledge CE, Leeb M, Wutz A, O'Neill LP, Nightingale KP, Turner BM.

Epigenetics Chromatin. 2013 May 1;6(1):11. doi: 10.1186/1756-8935-6-11.


Genes are often sheltered from the global histone hyperacetylation induced by HDAC inhibitors.

Halsall J, Gupta V, O'Neill LP, Turner BM, Nightingale KP.

PLoS One. 2012;7(3):e33453. doi: 10.1371/journal.pone.0033453. Epub 2012 Mar 30.


Elevated FOSB-expression; a potential marker of valproate sensitivity in AML.

Khanim FL, Bradbury CA, Arrazi J, Hayden RE, Rye A, Basu S, MacWhannell A, Sawers A, Griffiths M, Cook M, Freeman S, Nightingale KP, Grimwade D, Falciani F, Turner BM, Bunce CM, Craddock C.

Br J Haematol. 2009 Feb;144(3):332-41. doi: 10.1111/j.1365-2141.2008.07449.x. Epub 2008 Nov 22.


Directed evolution of a histone acetyltransferase--enhancing thermostability, whilst maintaining catalytic activity and substrate specificity.

Leemhuis H, Nightingale KP, Hollfelder F.

FEBS J. 2008 Nov;275(22):5635-47. doi: 10.1111/j.1742-4658.2008.06689.x.


The human histone acetyltransferase P/CAF is a promiscuous histone propionyltransferase.

Leemhuis H, Packman LC, Nightingale KP, Hollfelder F.

Chembiochem. 2008 Mar 3;9(4):499-503. doi: 10.1002/cbic.200700556. No abstract available.


Acetylation increases access of remodelling complexes to their nucleosome targets to enhance initiation of V(D)J recombination.

Nightingale KP, Baumann M, Eberharter A, Mamais A, Becker PB, Boyes J.

Nucleic Acids Res. 2007;35(18):6311-21. Epub 2007 Sep 18.


Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation.

Nightingale KP, Gendreizig S, White DA, Bradbury C, Hollfelder F, Turner BM.

J Biol Chem. 2007 Feb 16;282(7):4408-16. Epub 2006 Dec 13.


Histone modifications: signalling receptors and potential elements of a heritable epigenetic code.

Nightingale KP, O'Neill LP, Turner BM.

Curr Opin Genet Dev. 2006 Apr;16(2):125-36. Epub 2006 Feb 28. Review.


Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin.

Strohner R, Németh A, Nightingale KP, Grummt I, Becker PB, Längst G.

Mol Cell Biol. 2004 Feb;24(4):1791-8.


A critical epitope for substrate recognition by the nucleosome remodeling ATPase ISWI.

Clapier CR, Nightingale KP, Becker PB.

Nucleic Acids Res. 2002 Feb 1;30(3):649-55.


Critical role for the histone H4 N terminus in nucleosome remodeling by ISWI.

Clapier CR, Längst G, Corona DF, Becker PB, Nightingale KP.

Mol Cell Biol. 2001 Feb;21(3):875-83.


Two-step synergism between the progesterone receptor and the DNA-binding domain of nuclear factor 1 on MMTV minichromosomes.

Di Croce L, Koop R, Venditti P, Westphal HM, Nightingale KP, Corona DF, Becker PB, Beato M.

Mol Cell. 1999 Jul;4(1):45-54.


Global transcription regulators of eukaryotes.

Björklund S, Almouzni G, Davidson I, Nightingale KP, Weiss K.

Cell. 1999 Mar 19;96(6):759-67. No abstract available.


Structural and functional analysis of chromatin assembled from defined histones.

Nightingale KP, Becker PB.

Methods. 1998 Aug;15(4):343-53.


Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin.

Nightingale KP, Wellinger RE, Sogo JM, Becker PB.

EMBO J. 1998 May 15;17(10):2865-76.


The interaction of TFIIIA with specific RNA-DNA heteroduplexes.

Nightingale KP, Wolffe AP.

J Biol Chem. 1995 Sep 29;270(39):22665-8.


Light-activated cleavage of DNA by cobalt-bleomycin.

Nightingale KP, Fox KR.

Eur J Biochem. 1994 Feb 15;220(1):173-81.


DNA structure influences sequence specific cleavage by bleomycin.

Nightingale KP, Fox KR.

Nucleic Acids Res. 1993 Jun 11;21(11):2549-55.


Interaction of bleomycin with a bent DNA fragment.

Nightingale KP, Fox KR.

Biochem J. 1992 Jun 15;284 ( Pt 3):929-34.

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